Dr. Ko is a dedicated physiologist and teacher who studies sodium and calcium transport in the kidney, especially as they pertain to kidney stone disease. His integrated approach to scholarship and investigation spans basic science and translational research, with a focus on understanding the molecular mechanisms of renal tubular transport of cations in humans. Using urinary exosomal analyses, small but discrete packages of transporter proteins extruded from the epithelial cell into the urinary space, and a variety of molecular and biochemical techniques he is able to characterize the complex regulation of sodium and calcium homeostasis. His current projects include an examination the molecular mechanisms underlying calcium kidney stone formation and determining the hormonal regulators of the sodium chloride co-transporter. Dr. Ko has been heavily involved for a number of years in medical education including pre-med, medical, resident and fellow trainees. He is a fellow of the Academy of Distinguished Medical Educators and the co-director of the Tissues, Cell and Organ Physiology Course at the Pritzker School of Medicine. Nationally, he serves as the director for the American Society of Nephrology’s Tutored Research and Education of Kidney Scholars (TREKS) program at the University of Chicago.