Sodium Chloride Symporters
"Sodium Chloride Symporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS.
| Descriptor ID |
D049992
|
| MeSH Number(s) |
D12.776.157.530.450.625.374
|
| Concept/Terms |
Sodium Chloride Symporters- Sodium Chloride Symporters
- Chloride Symporters, Sodium
- Symporters, Sodium Chloride
- Sodium-Chloride Transporter
- Sodium Chloride Transporter
- Transporter, Sodium-Chloride
- Sodium-Chloride Cotransporter
- Cotransporter, Sodium-Chloride
- Sodium Chloride Cotransporter
- Na-Cl-Symporters
- Na Cl Symporters
- Sodium Chloride Cotransporters
- Chloride Cotransporters, Sodium
- Cotransporters, Sodium Chloride
|
Below are MeSH descriptors whose meaning is more general than "Sodium Chloride Symporters".
Below are MeSH descriptors whose meaning is more specific than "Sodium Chloride Symporters".
This graph shows the total number of publications written about "Sodium Chloride Symporters" by people in this website by year, and whether "Sodium Chloride Symporters" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sodium Chloride Symporters" by people in Profiles.
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The IFN?-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension. Circ Res. 2022 05 13; 130(10):1550-1564.
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The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate. Biochem J. 2016 10 01; 473(19):3237-52.
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Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension. Hypertension. 2016 07; 68(1):167-74.
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Mechanisms of angiotensin II stimulation of NCC are time-dependent in mDCT15 cells. Am J Physiol Renal Physiol. 2015 Apr 01; 308(7):F720-7.
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Cation-chloride cotransporters: regulation, physiological significance, and role in pathogenesis of arterial hypertension. Biochemistry (Mosc). 2014 Dec; 79(13):1546-61.
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Aldosterone acutely stimulates NCC activity via a SPAK-mediated pathway. Am J Physiol Renal Physiol. 2013 Sep 01; 305(5):F645-52.
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A new model of the distal convoluted tubule. Am J Physiol Renal Physiol. 2012 Sep; 303(5):F700-10.
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Parathyroid hormone (PTH) regulates the sodium chloride cotransporter via Ras guanyl releasing protein 1 (Ras-GRP1) and extracellular signal-regulated kinase (ERK)1/2 mitogen-activated protein kinase (MAPK) pathway. Transl Res. 2011 Nov; 158(5):282-9.
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Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway. J Am Soc Nephrol. 2011 Sep; 22(9):1707-19.
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Molecular physiology of the thiazide-sensitive sodium-chloride cotransporter. Curr Opin Nephrol Hypertens. 2009 Sep; 18(5):421-7.