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Shin Tsunekawa

AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Asano S, Himeno T, Hayami T, Motegi M, Inoue R, Nakai-Shimoda H, Miura-Yura E, Morishita Y, Kondo M, Tsunekawa S, Kato Y, Kato K, Naruse K, Nakamura J, Kamiya H. Ranirestat Improved Nerve Conduction Velocities, Sensory Perception, and Intraepidermal Nerve Fiber Density in Rats with Overt Diabetic Polyneuropathy. J Diabetes Res. 2019; 2019:2756020. PMID: 31828158.
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    2. Araki K, Araki A, Honda D, Izumoto T, Hashizume A, Hijikata Y, Yamada S, Iguchi Y, Hara A, Ikumi K, Kawai K, Ishigaki S, Nakamichi Y, Tsunekawa S, Seino Y, Yamamoto A, Takayama Y, Hidaka S, Tominaga M, Ohara-Imaizumi M, Suzuki A, Ishiguro H, Enomoto A, Yoshida M, Arima H, Muramatsu SI, Sobue G, Katsuno M. TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets. J Clin Invest. 2019 Jul 29; 130:3578-3593. PMID: 31355778.
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    3. Miura-Yura E, Tsunekawa S, Naruse K, Nakamura N, Motegi M, Nakai-Shimoda H, Asano S, Kato M, Yamada Y, Izumoto-Akita T, Yamamoto A, Himeno T, Kondo M, Kato Y, Nakamura J, Kamiya H. Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin-induced diabetic mice. J Diabetes Investig. 2020 Jan; 11(1):28-38. PMID: 31144464.
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    4. Mohiuddin MS, Himeno T, Inoue R, Miura-Yura E, Yamada Y, Nakai-Shimoda H, Asano S, Kato M, Motegi M, Kondo M, Seino Y, Tsunekawa S, Kato Y, Suzuki A, Naruse K, Kato K, Nakamura J, Kamiya H. Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult. J Diabetes Res. 2019; 2019:9426014. PMID: 30918901.
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    5. Shibata Y, Himeno T, Kamiya T, Tani H, Nakayama T, Kojima C, Sugiura-Roth Y, Naito E, Kondo M, Tsunekawa S, Kato Y, Nakamura J, Kamiya H. Validity and reliability of a point-of-care nerve conduction device in diabetes patients. J Diabetes Investig. 2019 Sep; 10(5):1291-1298. PMID: 30659760.
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    6. Tsunekawa S, Kamiya H, Nakamura J. Different trends in causes of death in patients with diabetes between Japan and the USA. J Diabetes Investig. 2019 May; 10(3):571-573. PMID: 30341830.
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    7. Murase M, Seino Y, Maekawa R, Iida A, Hosokawa K, Hayami T, Tsunekawa S, Hamada Y, Yokoi N, Seino S, Hayashi Y, Arima H. Functional adenosine triphosphate-sensitive potassium channel is required in high-carbohydrate diet-induced increase in ß-cell mass. J Diabetes Investig. 2019 Mar; 10(2):238-250. PMID: 30084544.
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    8. Maekawa R, Ogata H, Murase M, Harada N, Suzuki K, Joo E, Sankoda A, Iida A, Izumoto T, Tsunekawa S, Hamada Y, Oiso Y, Inagaki N, Arima H, Hayashi Y, Seino Y. Glucose-dependent insulinotropic polypeptide is required for moderate high-fat diet- but not high-carbohydrate diet-induced weight gain. Am J Physiol Endocrinol Metab. 2018 06 01; 314(6):E572-E583. PMID: 29406782.
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    9. Maekawa R, Seino Y, Ogata H, Murase M, Iida A, Hosokawa K, Joo E, Harada N, Tsunekawa S, Hamada Y, Oiso Y, Inagaki N, Hayashi Y, Arima H. Chronic high-sucrose diet increases fibroblast growth factor 21 production and energy expenditure in mice. J Nutr Biochem. 2017 11; 49:71-79. PMID: 28886439.
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    10. Hosokawa K, Hamada Y, Fujiya A, Murase M, Maekawa R, Niwa Y, Izumoto T, Seino Y, Tsunekawa S, Arima H. S100B impairs glycolysis via enhanced poly(ADP-ribosyl)ation of glyceraldehyde-3-phosphate dehydrogenase in rodent muscle cells. Am J Physiol Endocrinol Metab. 2017 06 01; 312(6):E471-E481. PMID: 28174179.
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    11. Iida A, Seino Y, Fukami A, Maekawa R, Yabe D, Shimizu S, Kinoshita K, Takagi Y, Izumoto T, Ogata H, Ishikawa K, Ozaki N, Tsunekawa S, Hamada Y, Oiso Y, Arima H, Hayashi Y. Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin. Diabetologia. 2016 07; 59(7):1533-1541. PMID: 27053237.
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    12. Izumoto-Akita T, Tsunekawa S, Yamamoto A, Uenishi E, Ishikawa K, Ogata H, Iida A, Ikeniwa M, Hosokawa K, Niwa Y, Maekawa R, Yamauchi Y, Seino Y, Hamada Y, Hibi H, Arima H, Ueda M, Oiso Y. Secreted factors from dental pulp stem cells improve glucose intolerance in streptozotocin-induced diabetic mice by increasing pancreatic ß-cell function. BMJ Open Diabetes Res Care. 2015; 3(1):e000128. PMID: 26504525.
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    13. Ochiai H, Suga H, Yamada T, Sakakibara M, Kasai T, Ozone C, Ogawa K, Goto M, Banno R, Tsunekawa S, Sugimura Y, Arima H, Oiso Y. BMP4 and FGF strongly induce differentiation of mouse ES cells into oral ectoderm. Stem Cell Res. 2015 Sep; 15(2):290-8. PMID: 26209816.
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    14. Niwa Y, Ishikawa K, Ishigami M, Honda T, Achiwa K, Izumoto T, Maekawa R, Hosokawa K, Iida A, Seino Y, Hamada Y, Goto H, Oiso Y, Arima H, Tsunekawa S. Effect of hyperglycemia on hepatocellular carcinoma development in diabetes. Biochem Biophys Res Commun. 2015 Jul 31; 463(3):344-50. PMID: 26022129.
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    15. Seino Y, Ogata H, Maekawa R, Izumoto T, Iida A, Harada N, Miki T, Seino S, Inagaki N, Tsunekawa S, Oiso Y, Hamada Y. Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: Role of adenosine triphosphate-sensitive K(+) channels. J Diabetes Investig. 2015 Sep; 6(5):522-6. PMID: 26417408.
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    16. Kobayashi K, Imagama S, Tsunekawa S, Hosokawa K, Watanabe M, Ito Z, Ando K, Ishiguro N. Spinal metastasis from struma ovarii: case report and review of the literature. Asian Spine J. 2015 Apr; 9(2):281-5. PMID: 25901242.
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    17. Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y. Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity. PLoS One. 2015; 10(2):e0115350. PMID: 25658116.
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    18. Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y. KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state. J Endocrinol. 2014 Aug; 222(2):191-200. PMID: 24891433.
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    19. Kato J, Kamiya H, Himeno T, Shibata T, Kondo M, Okawa T, Fujiya A, Fukami A, Uenishi E, Seino Y, Tsunekawa S, Hamada Y, Naruse K, Oiso Y, Nakamura J. Mesenchymal stem cells ameliorate impaired wound healing through enhancing keratinocyte functions in diabetic foot ulcerations on the plantar skin of rats. J Diabetes Complications. 2014 Sep-Oct; 28(5):588-95. PMID: 25027388.
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    20. Ochiai H, Okazaki H, Ogata H, Suga H, Tsunekawa S, Oiso Y. [Case report; A case of fulminant type 1 diabetes associated with drug-induced hypersensitivity syndrome]. Nihon Naika Gakkai Zasshi. 2014 May 10; 103(5):1183-6. PMID: 25026790.
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    21. Okawa T, Kamiya H, Himeno T, Seino Y, Tsunekawa S, Hayashi Y, Harada N, Yamada Y, Inagaki N, Seino Y, Oiso Y, Nakamura J. Sensory and motor physiological functions are impaired in gastric inhibitory polypeptide receptor-deficient mice. J Diabetes Investig. 2014 Feb 12; 5(1):31-7. PMID: 24843734.
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    22. Fujiya A, Nagasaki H, Seino Y, Okawa T, Kato J, Fukami A, Himeno T, Uenishi E, Tsunekawa S, Kamiya H, Nakamura J, Oiso Y, Hamada Y. The role of S100B in the interaction between adipocytes and macrophages. Obesity (Silver Spring). 2014 Feb; 22(2):371-9. PMID: 23804363.
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    23. Okawa T, Tsunekawa S, Seino Y, Hamada Y, Oiso Y. Deceptive HbA1c in a patient with pure red cell aplasia. Lancet. 2013 Jul 27; 382(9889):366. PMID: 23890045.
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    24. Fukami A, Seino Y, Ozaki N, Yamamoto M, Sugiyama C, Sakamoto-Miura E, Himeno T, Takagishi Y, Tsunekawa S, Ali S, Drucker DJ, Murata Y, Seino Y, Oiso Y, Hayashi Y. Ectopic expression of GIP in pancreatic ß-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides. Diabetes. 2013 Feb; 62(2):510-8. PMID: 23099862.
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    25. Sakamoto E, Seino Y, Fukami A, Mizutani N, Tsunekawa S, Ishikawa K, Ogata H, Uenishi E, Kamiya H, Hamada Y, Sato H, Harada N, Toyoda Y, Miwa I, Nakamura J, Inagaki N, Oiso Y, Ozaki N. Ingestion of a moderate high-sucrose diet results in glucose intolerance with reduced liver glucokinase activity and impaired glucagon-like peptide-1 secretion. J Diabetes Investig. 2012 Oct 18; 3(5):432-40. PMID: 24843603.
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    26. Okawa T, Kamiya H, Himeno T, Kato J, Seino Y, Fujiya A, Kondo M, Tsunekawa S, Naruse K, Hamada Y, Ozaki N, Cheng Z, Kito T, Suzuki H, Ito S, Oiso Y, Nakamura J, Isobe K. Transplantation of neural crest-like cells derived from induced pluripotent stem cells improves diabetic polyneuropathy in mice. Cell Transplant. 2013; 22(10):1767-83. PMID: 23051637.
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    27. Demozay D, Tsunekawa S, Briaud I, Shah R, Rhodes CJ. Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet ß-cells. Diabetes. 2011 Nov; 60(11):2892-902. PMID: 21940781.
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    28. Tsunekawa S, Demozay D, Briaud I, McCuaig J, Accili D, Stein R, Rhodes CJ. FoxO feedback control of basal IRS-2 expression in pancreatic ß-cells is distinct from that in hepatocytes. Diabetes. 2011 Nov; 60(11):2883-91. PMID: 21933986.
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    29. Tsunekawa S, Arai J, Ishihara Y, Fujii Y. [MBL quality control survey of autoantibodies--25 years of activity and its achievement--mainly antinuclear antibodies]. Rinsho Byori. 2010 Feb; 58(2):131-8. PMID: 20229811.
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    30. Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh Y, Kaneko Y, Kimura T, Ariyoshi Y, Miura Y, Oiso Y, Niki I. Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies. J Endocrinol. 2007 Apr; 193(1):65-74. PMID: 17400804.
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    31. Yashima M, Tsunekawa S. Structures and the oxygen deficiency of tetragonal and monoclinic zirconium oxide nanoparticles. Acta Crystallogr B. 2006 Feb; 62(Pt 1):161-4. PMID: 16434804.
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    32. Tsunekawa S, Miura Y, Yamamoto N, Itoh Y, Ariyoshi Y, Senda T, Oiso Y, Niki I. Systemic administration of pituitary adenylate cyclase-activating polypeptide maintains beta-cell mass and retards onset of hyperglycaemia in beta-cell-specific calmodulin-overexpressing transgenic mice. Eur J Endocrinol. 2005 May; 152(5):805-11. PMID: 15879367.
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    33. Miura Y, Yamamoto N, Tsunekawa S, Taguchi S, Eguchi Y, Ozaki N, Oiso Y. Replacement of valsartan and candesartan by telmisartan in hypertensive patients with type 2 diabetes: metabolic and antiatherogenic consequences. Diabetes Care. 2005 Mar; 28(3):757-8. PMID: 15735228.
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    34. Veitenhansl M, Stegner K, Hierl FX, Dieterle C, Feldmeier H, Gutt B, Landgraf R, Garrow AP, Vileikyte L, Findlow A, Waterman C, Boulton AJ, Shankhdhar K, Shankhdhar L, Shankhdhar U, Petrova NL, Foster AV, Edmonds ME, Ferraresi R, Caravaggi C, De Giglio R, Cavaiani P, Pogliaghi I, Sommariva E, Katz IA, Harlan A, Miranda-Palma B, Prieto-Sanchez L, Armstrong DG, Bowker JH, Mizel MS, Cernea S, Wohlgelernter J, Kidron M, Modi P, Raz I, Arbit E, Nosek L, Kapitza C, Beckett P, Gelfand R, Goldberg M, Heise T, Testa MA, Turner RR, Hayes JF, Scranton RE, Simonson DC, Yang YW, Hsu YJ, Naujok O, Francini F, Jörns A, Tiedge M, Lenzen S, Abdel-Wahab YH, Marenah L, Orr DF, Shaw C, Flatt PR, Chokkalingam K, Mansell PI, Clausen P, Ekbom P, Damm P, Feldt-Rasmussen U, Nielsen B, Mathiesen ER, Feldt-Rasmussen B, Dewan S, Da Silva N, Ternan PM, Leong KS, Wilding JP, Asatiani N, Kurashvili R, Dundua M, Shelestova E, Pagava K, Ramazashvili M, Hod M, Smirnov S, Petersen JL, Justesen TI, Ringholm Nielsen L, Müller C, Højlund K, Wensaas A, Kase ET, Aas V, Rustan AC, Thoresen GH, Levin K, Beck-Nielsen H, Gaster M, Im SS, Kang SY, Kim SY, Ahn YH, Lihn AS, Schmoll D, Werner T, Kienitz A, Meyer M, Barthel A, Ailett F, Sutherland C, Walther R, Grempler R, Sasson S, Reich R, Tenenbaum T, Alpert E, Anfossi G, Russo I, Traversa M, Massucco P, Mattiello L, Doronzo G, Trovati M, Lally S, Tan CY, Owens D, Tomkin GH, Porchay I, Péan F, Bellili N, Betoulle D, Balkau B, Tichet J, Marre M, Fumeron F. 40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004. Diabetologia. 2004 Aug; 47(Suppl 1):A1-A464. PMID: 27770180.
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    35. Kawahata K, Misaki Y, Yamauchi M, Tsunekawa S, Setoguchi K, Miyazaki J, Yamamoto K. Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J Immunol. 2002 May 01; 168(9):4399-405. PMID: 11970982.
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    36. Kawahata K, Misaki Y, Yamauchi M, Tsunekawa S, Setoguchi K, Miyazaki J, Yamamoto K. Peripheral tolerance to a nuclear autoantigen: dendritic cells expressing a nuclear autoantigen lead to persistent anergic state of CD4+ autoreactive T cells after proliferation. J Immunol. 2002 Feb 01; 168(3):1103-12. PMID: 11801644.
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    37. Ikemoto M, Tsunekawa S, Awane M, Fukuda Y, Murayama H, Igarashi M, Nagata A, Kasai Y, Totani M. A useful ELISA system for human liver-type arginase, and its utility in diagnosis of liver diseases. Clin Biochem. 2001 Sep; 34(6):455-61. PMID: 11676974.
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    38. Ikemoto M, Tsunekawa S, Kasai Y, Tanaka K, Ueda K, Totani M. [Clinical significance of anti-liver-type arginase autoantibody in blood of recipients after partial liver transplantation]. Rinsho Byori. 2001 Jul; 49(7):651-6. PMID: 11519124.
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    39. Ikemoto M, Tsunekawa S, Toda Y, Totani M. Liver-type arginase is a highly sensitive marker for hepatocellular damage in rats. Clin Chem. 2001 May; 47(5):946-8. PMID: 11325904.
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    40. Kawahata K, Misaki Y, Komagata Y, Setoguchi K, Tsunekawa S, Yoshikawa Y, Miyazaki J, Yamamoto K. Altered expression level of a systemic nuclear autoantigen determines the fate of immune response to self. J Immunol. 1999 Jun 01; 162(11):6482-91. PMID: 10352263.
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    41. Kanazawa A, Tanaka A, Iwata S, Satoh S, Hatano E, Shinohara H, Kitai T, Tsunekawa S, Ikai I, Yamamoto M, Takahashi R, Chance B, Yamaoka Y. The beneficial effect of phosphocreatine accumulation in the creatine kinase transgenic mouse liver in endotoxin-induced hepatic cell death. J Surg Res. 1998 Dec; 80(2):229-35. PMID: 9878318.
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    42. Kitai T, Shinohara H, Hatano E, Sato S, Kanazawa A, Tsunekawa S, Yamamoto M, Yamaoka Y, Uemoto S, Inomata Y, Tanaka K, Tanaka A. Postoperative monitoring of the oxygenation state of the graft liver in cases with hepatopulmonary syndrome. Transplantation. 1996 Dec 15; 62(11):1676-8. PMID: 8970628.
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    43. Hatano E, Tanaka A, Iwata S, Satoh S, Kitai T, Tsunekawa S, Inomoto T, Shinohara H, Chance B, Yamaoka Y. Induction of endotoxin tolerance in transgenic mouse liver expressing creatine kinase. Hepatology. 1996 Sep; 24(3):663-9. PMID: 8781340.
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    44. Tanaka A, Morimoto T, Ozaki N, Ikai I, Yamamoto Y, Tsunekawa S, Kitai T, Yamaoka Y. Extension of surgical indication for advanced hepatocellular carcinoma: is it possible to prolong life span or improve quality of life? Hepatogastroenterology. 1996 Sep-Oct; 43(11):1172-81. PMID: 8908547.
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    45. Dignass AU, Tsunekawa S, Podolsky DK. Fibroblast growth factors modulate intestinal epithelial cell growth and migration. Gastroenterology. 1994 May; 106(5):1254-62. PMID: 7513666.
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    46. Ikemoto M, Ishida A, Tsunekawa S, Ozawa K, Kasai Y, Totani M, Ueda K. Enzyme immunoassay of liver-type arginase and its potential clinical application. Clin Chem. 1993 May; 39(5):794-9. PMID: 8387407.
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    47. Takano E, Ueda M, Tsunekawa S, Murakami T, Maki M, Hatanaka M, Murachi T. Molecular diversity of erythrocyte calpastatin. Biomed Biochim Acta. 1991; 50(4-6):517-21. PMID: 1801717.
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    48. Mukawa A, Kamitsuma Y, Tsunekawa S, Tanaka N. Report on a long-term trial of CYBEST Model 2 for prescreening for squamous cell carcinoma of the uterine cervix. Anal Cell Pathol. 1989 Aug; 1(4):225-33. PMID: 2487047.
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    49. Mukawa A, Tsunekawa S. [Automation of cytodiagnosis by image processing--CYBEST as an example]. Rinsho Byori. 1985 Feb; Spec No 61:3-15. PMID: 3999413.
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    50. Tanaka N, Ueno T, Ikeda H, Mukawa A, Ishikawa A, Konoike K, Shimaoka Y, Hosoi S, Okamoto Y, Tsunekawa S, Watanabe S. [Automation of cancer cytology utilizing the image analysis system: from fundamental research to practical use]. Rinsho Byori. 1982 Jun; 30(6):571-85. PMID: 7131826.
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    51. Tanaka N, Ueno T, Ikeda H, Watanabe S, Tsunekawa S, Hosoi S, Okamoto Y. [Automation of cytodiagnosis: present status and future prospect]. Rinsho Byori. 1980; Suppl:201-15. PMID: 7411959.
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