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Chung-I Wu

InstitutionUniversity of Chicago
DepartmentEcology and Evolution
AddressChicago IL 60637
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    Collapse Research 
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    R01GM063144     (WU, CHUNG-I)May 1, 2001 - Jun 30, 2010
    Transcriptional and genic basis of incipient speciation
    Role: Principal Investigator

    R01GM058686     (WU, CHUNG-I)Jan 1, 1999 - Jun 30, 2011
    MicroRNA evolution and species divergence in Drosophila
    Role: Principal Investigator

    K04HG000005     (WU, CHUNG-I)Sep 28, 1990 - Aug 31, 1995
    Role: Principal Investigator

    R01GM039902     (WU, CHUNG-I)Apr 1, 1988 - Mar 31, 1994
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hungate EA, Earley EJ, Boussy IA, Turissini DA, Ting CT, Moran JR, Wu ML, Wu CI, Jones CD. A locus in Drosophila sechellia affecting tolerance of a host plant toxin. Genetics. 2013 Nov; 195(3):1063-75. PMID: 24037270; PMCID: PMC3813837.
      Citations: 17     Fields:    Translation:Animals
    2. Zheng C, Miao X, Li Y, Huang Y, Ruan J, Ma X, Wang L, Wu CI, Cai J. Determination of genomic copy number alteration emphasizing a restriction site-based strategy of genome re-sequencing. Bioinformatics. 2013 Nov 15; 29(22):2813-21. PMID: 23962614.
      Citations: 2     Fields:    Translation:Humans
    3. Lu J, Shen Y, Carthew RW, Wang SM, Wu CI. Reply to evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nat Genet. 2010 Jan; 42(1):9-10. PMID: 25067898; PMCID: PMC4108203.
      Citations: 5     Fields:    
    4. Wu CI, Shen Y, Tang T. Evolution under canalization and the dual roles of microRNAs: a hypothesis. Genome Res. 2009 May; 19(5):734-43. PMID: 19411598; PMCID: PMC3647535.
      Citations: 87     Fields:    Translation:HumansAnimals
    5. Wu Q, Kim YC, Lu J, Xuan Z, Chen J, Zheng Y, Zhou T, Zhang MQ, Wu CI, Wang SM. Poly A- transcripts expressed in HeLa cells. PLoS One. 2008 Jul 30; 3(7):e2803. PMID: 18665230; PMCID: PMC2481391.
      Citations: 48     Fields:    Translation:HumansCells
    6. Lu J, Fu Y, Kumar S, Shen Y, Zeng K, Xu A, Carthew R, Wu CI. Adaptive evolution of newly emerged micro-RNA genes in Drosophila. Mol Biol Evol. 2008 May; 25(5):929-38. PMID: 18296702; PMCID: PMC3707409.
      Citations: 44     Fields:    Translation:Animals
    7. Lu J, Shen Y, Wu Q, Kumar S, He B, Shi S, Carthew RW, Wang SM, Wu CI. The birth and death of microRNA genes in Drosophila. Nat Genet. 2008 Mar; 40(3):351-5. PMID: 18278047.
      Citations: 148     Fields:    Translation:AnimalsCells
    8. Zeng K, Shi S, Wu CI. Compound tests for the detection of hitchhiking under positive selection. Mol Biol Evol. 2007 Aug; 24(8):1898-908. PMID: 17557886.
      Citations: 48     Fields:    
    9. Zeng K, Mano S, Shi S, Wu CI. Comparisons of site- and haplotype-frequency methods for detecting positive selection. Mol Biol Evol. 2007 Jul; 24(7):1562-74. PMID: 17449894.
      Citations: 30     Fields:    
    10. Shapiro JA, Huang W, Zhang C, Hubisz MJ, Lu J, Turissini DA, Fang S, Wang HY, Hudson RR, Nielsen R, Chen Z, Wu CI. Adaptive genic evolution in the Drosophila genomes. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2271-6. PMID: 17284599; PMCID: PMC1892965.
      Citations: 125     Fields:    Translation:Animals
    11. Zeng K, Fu YX, Shi S, Wu CI. Statistical tests for detecting positive selection by utilizing high-frequency variants. Genetics. 2006 Nov; 174(3):1431-9. PMID: 16951063; PMCID: PMC1667063.
      Citations: 143     Fields:    Translation:Animals
    12. Osada N, Kohn MH, Wu CI. Genomic inferences of the cis-regulatory nucleotide polymorphisms underlying gene expression differences between Drosophila melanogaster mating races. Mol Biol Evol. 2006 Aug; 23(8):1585-91. PMID: 16754642.
      Citations: 16     Fields:    Translation:AnimalsCells
    13. Greenberg AJ, Moran JR, Wu CI. Proper control of genetic background with precise allele substitution: a comment on Coyne and Elwyn. Evolution. 2006 Mar; 60(3):623-5; discussion 626-7. PMID: 16637506.
      Citations: 4     Fields:    Translation:HumansAnimals
    14. Lu J, Tang T, Tang H, Huang J, Shi S, Wu CI. The accumulation of deleterious mutations in rice genomes: a hypothesis on the cost of domestication. Trends Genet. 2006 Mar; 22(3):126-31. PMID: 16443304.
      Citations: 84     Fields:    Translation:Animals
    15. Greenberg AJ, Wu CI, SMBE Tri-National Young Investigators. Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005. Molecular genetics of natural populations. Mol Biol Evol. 2006 May; 23(5):883-6. PMID: 16361304.
      Citations:    Fields:    Translation:HumansAnimals
    16. Greenberg AJ, Moran JR, Fang S, Wu CI. Adaptive loss of an old duplicated gene during incipient speciation. Mol Biol Evol. 2006 Feb; 23(2):401-10. PMID: 16251509.
      Citations: 15     Fields:    Translation:Animals
    17. Tang H, Wu CI. A new method for estimating nonsynonymous substitutions and its applications to detecting positive selection. Mol Biol Evol. 2006 Feb; 23(2):372-9. PMID: 16237204.
      Citations: 13     Fields:    Translation:HumansAnimals
    18. Lee S, Bao J, Zhou G, Shapiro J, Xu J, Shi RZ, Lu X, Clark T, Johnson D, Kim YC, Wing C, Tseng C, Sun M, Lin W, Wang J, Yang H, Wang J, Du W, Wu CI, Zhang X, Wang SM. Detecting novel low-abundant transcripts in Drosophila. RNA. 2005 Jun; 11(6):939-46. PMID: 15923377; PMCID: PMC1370778.
      Citations: 19     Fields:    Translation:AnimalsCells
    19. Alipaz JA, Fang S, Osada N, Wu CI. Evolution of sexual isolation during secondary contact: genotypic versus phenotypic changes in laboratory populations. Am Nat. 2005 Apr; 165(4):420-8. PMID: 15791534.
      Citations: 4     Fields:    Translation:Animals
    20. Alipaz JA, Karr TL, Wu CI. Evolution of sexual isolation in laboratory populations: fitness differences between mating types and the associated hybrid incompatibilities. Am Nat. 2005 Apr; 165(4):429-38. PMID: 15791535.
      Citations: 4     Fields:    Translation:Animals
    21. Lu J, Wu CI. Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee. Proc Natl Acad Sci U S A. 2005 Mar 15; 102(11):4063-7. PMID: 15728731; PMCID: PMC554819.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    22. Osada N, Wu CI. Inferring the mode of speciation from genomic data: a study of the great apes. Genetics. 2005 Jan; 169(1):259-64. PMID: 15677748; PMCID: PMC1448895.
      Citations: 29     Fields:    Translation:HumansAnimals
    23. Sun S, Ting CT, Wu CI. The normal function of a speciation gene, Odysseus, and its hybrid sterility effect. Science. 2004 Jul 02; 305(5680):81-3. PMID: 15232104.
      Citations: 53     Fields:    Translation:Animals
    24. Tang H, Wyckoff GJ, Lu J, Wu CI. A universal evolutionary index for amino acid changes. Mol Biol Evol. 2004 Aug; 21(8):1548-56. PMID: 15140949.
      Citations: 18     Fields:    Translation:HumansAnimals
    25. Wu CI, Shi S, Zhang YP. A case for conservation. Nature. 2004 Mar 11; 428(6979):213-4. PMID: 15014510.
      Citations: 2     Fields:    Translation:Animals
    26. Wu CI, Ting CT. Genes and speciation. Nat Rev Genet. 2004 Feb; 5(2):114-22. PMID: 14735122.
      Citations: 163     Fields:    Translation:Animals
    27. Kohn MH, Fang S, Wu CI. Inference of positive and negative selection on the 5' regulatory regions of Drosophila genes. Mol Biol Evol. 2004 Feb; 21(2):374-83. PMID: 14660692.
      Citations: 31     Fields:    Translation:AnimalsCells
    28. Greenberg AJ, Moran JR, Coyne JA, Wu CI. Ecological adaptation during incipient speciation revealed by precise gene replacement. Science. 2003 Dec 05; 302(5651):1754-7. PMID: 14657496.
      Citations: 55     Fields:    Translation:Animals
    29. Lu J, Li WH, Wu CI. Comment on "Chromosomal speciation and molecular divergence-accelerated evolution in rearranged chromosomes". Science. 2003 Nov 07; 302(5647):988; author reply 988. PMID: 14605352.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    30. Wu CI, Xu EY. Sexual antagonism and X inactivation--the SAXI hypothesis. Trends Genet. 2003 May; 19(5):243-7. PMID: 12711214.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    31. Fang S, Takahashi A, Wu CI, Fang S, Takahashi A, Wu CI. A mutation in the promoter of desaturase 2 is correlated with sexual isolation between Drosophila behavioral races. Genetics. 2002 Oct; 162(2):781-4. PMID: 12399388; PMCID: PMC1462294.
      Citations: 28     Fields:    Translation:AnimalsCells
    32. Fay JC, Wyckoff GJ, Wu CI. Testing the neutral theory of molecular evolution with genomic data from Drosophila. Nature. 2002 Feb 28; 415(6875):1024-6. PMID: 11875569.
      Citations: 139     Fields:    Translation:Animals
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