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Last Name
Institution

Steven Levin

TitleClinical Assistant Professor
InstitutionUniversity of Chicago
DepartmentOrthopaedic Surg & Rehab Med
AddressChicago IL 60637
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Murphy GS, Szokol JW, Avram MJ, Greenberg SB, Shear TD, Vender JS, Levin SD, Koh JL, Parikh KN, Patel SS. Effect of ventilation on cerebral oxygenation in patients undergoing surgery in the beach chair position: a randomized controlled trial. Br J Anaesth. 2014 Oct; 113(4):618-27. PMID: 24860157.
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    2. Levin SD, Wellman DS, Liu C, Li Y, Ren Y, Shah NA, Zhang LQ. Biomechanical strain characteristics of soft tissue biceps tenodesis and bony tenodesis. J Orthop Sci. 2013 Sep; 18(5):699-704. PMID: 23892426.
      View in: PubMed
    3. Koh JL, Levin SD, Chehab EL, Murphy GS. Neer Award 2012: cerebral oxygenation in the beach chair position: a prospective study on the effect of general anesthesia compared with regional anesthesia and sedation. J Shoulder Elbow Surg. 2013 Oct; 22(10):1325-31. PMID: 23571083.
      View in: PubMed
    4. Song X, Zhu S, Shi P, Liu Y, Shi Y, Levin SD, Qian Y. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat Immunol. 2011 Oct 12; 12(12):1151-8. PMID: 21993849.
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    5. Wojno ED, Hosken N, Stumhofer JS, O'Hara AC, Mauldin E, Fang Q, Turka LA, Levin SD, Hunter CA. A role for IL-27 in limiting T regulatory cell populations. J Immunol. 2011 Jul 01; 187(1):266-73. PMID: 21622862.
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    6. Levin SD, Taft DW, Brandt CS, Bucher C, Howard ED, Chadwick EM, Johnston J, Hammond A, Bontadelli K, Ardourel D, Hebb L, Wolf A, Bukowski TR, Rixon MW, Kuijper JL, Ostrander CD, West JW, Bilsborough J, Fox B, Gao Z, Xu W, Ramsdell F, Blazar BR, Lewis KE. Vstm3 is a member of the CD28 family and an important modulator of T-cell function. Eur J Immunol. 2011 Apr; 41(4):902-15. PMID: 21416464.
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    7. Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK. Cutting edge: TIGIT has T cell-intrinsic inhibitory functions. J Immunol. 2011 Feb 01; 186(3):1338-42. PMID: 21199897.
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    8. Stumhofer JS, Tait ED, Quinn WJ, Hosken N, Spudy B, Goenka R, Fielding CA, O'Hara AC, Chen Y, Jones ML, Saris CJ, Rose-John S, Cua DJ, Jones SA, Elloso MM, Grötzinger J, Cancro MP, Levin SD, Hunter CA. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol. 2010 Dec; 11(12):1119-26. PMID: 21057510.
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    9. Khan N, Levin SD, Domont ZB, Wu YN, Ren Y, Zhang LQ. Strain effects of placing an arthroscopic portal through the subscapularis tendon. J Shoulder Elbow Surg. 2011 Jan; 20(1):33-8. PMID: 21051243.
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    10. Kemp KL, Levin SD, Stein PL. Lck regulates IL-10 expression in memory-like Th1 cells. Eur J Immunol. 2010 Nov; 40(11):3210-9. PMID: 21061443.
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    11. Wellman DS, McCoy BW, Levin SD, Knight BP. Shoulder arthroscopy in patients with a cardiac pacemaker or defibrillator: a case report and discussion of perioperative management. J Shoulder Elbow Surg. 2010 Dec; 19(8):1204-9. PMID: 20656525.
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    12. Kemp KL, Levin SD, Bryce PJ, Stein PL. Lck mediates Th2 differentiation through effects on T-bet and GATA-3. J Immunol. 2010 Apr 15; 184(8):4178-84. PMID: 20237292.
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    13. Mabry R, Lewis KE, Moore M, McKernan PA, Bukowski TR, Bontadelli K, Brender T, Okada S, Lum K, West J, Kuijper JL, Ardourel D, Franke S, Lockwood L, Vu T, Frank A, Appleby MW, Wolf A, Reardon B, Hamacher NB, Stevens B, Lewis P, Lewis KB, Gilbertson DG, Lantry M, Julien SH, Ostrander C, Chan C, Byrnes-Blake K, Brody J, Presnell S, Meengs B, Levin SD, Snavely M. Engineering of stable bispecific antibodies targeting IL-17A and IL-23. Protein Eng Des Sel. 2010 Mar; 23(3):115-27. PMID: 20022918.
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    14. Levin SD. IL-17 receptor signaling: ubiquitin gets in on the act. Sci Signal. 2009 Oct 13; 2(92):pe64. PMID: 19825826.
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    15. Brandt CS, Baratin M, Yi EC, Kennedy J, Gao Z, Fox B, Haldeman B, Ostrander CD, Kaifu T, Chabannon C, Moretta A, West R, Xu W, Vivier E, Levin SD. The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med. 2009 Jul 06; 206(7):1495-503. PMID: 19528259.
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    16. Yang S, Park HS, Flores S, Levin SD, Makhsous M, Lin F, Koh J, Nuber G, Zhang LQ. Biomechanical analysis of bursal-sided partial thickness rotator cuff tears. J Shoulder Elbow Surg. 2009 May-Jun; 18(3):379-85. PMID: 19269860.
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    17. Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, Harder B, Okada S, Ostrander CD, Kreindler JL, Aujla SJ, Reardon B, Moore M, Shea P, Schreckhise R, Bukowski TR, Presnell S, Guerra-Lewis P, Parrish-Novak J, Ellsworth JL, Jaspers S, Lewis KE, Appleby M, Kolls JK, Rixon M, West JW, Gao Z, Levin SD. Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol. 2007 Oct 15; 179(8):5462-73. PMID: 17911633.
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    18. Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, Haugen HS, Maurer M, Harder B, Johnston J, Bort S, Mudri S, Kuijper JL, Bukowski T, Shea P, Dong DL, Dasovich M, Grant FJ, Lockwood L, Levin SD, LeCiel C, Waggie K, Day H, Topouzis S, Kramer J, Kuestner R, Chen Z, Foster D, Parrish-Novak J, Gross JA. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol. 2004 Jul; 5(7):752-60. PMID: 15184896.
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    19. Yu XZ, Levin SD, Madrenas J, Anasetti C. Lck is required for activation-induced T cell death after TCR ligation with partial agonists. J Immunol. 2004 Feb 01; 172(3):1437-43. PMID: 14734719.
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    20. Sicinska E, Aifantis I, Le Cam L, Swat W, Borowski C, Yu Q, Ferrando AA, Levin SD, Geng Y, von Boehmer H, Sicinski P. Requirement for cyclin D3 in lymphocyte development and T cell leukemias. Cancer Cell. 2003 Dec; 4(6):451-61. PMID: 14706337.
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    21. Soller BR, Idwasi PO, Balaguer J, Levin S, Simsir SA, Vander Salm TJ, Collette H, Heard SO. Noninvasive, near infrared spectroscopic-measured muscle pH and PO2 indicate tissue perfusion for cardiac surgical patients undergoing cardiopulmonary bypass. Crit Care Med. 2003 Sep; 31(9):2324-31. PMID: 14501963.
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    22. Filipp D, Zhang J, Leung BL, Shaw A, Levin SD, Veillette A, Julius M. Regulation of Fyn through translocation of activated Lck into lipid rafts. J Exp Med. 2003 May 05; 197(9):1221-7. PMID: 12732664.
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    23. Huang J, Lo PF, Zal T, Gascoigne NR, Smith BA, Levin SD, Grey HM. CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9369-73. PMID: 12077322.
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    24. Isaksen DE, Baumann H, Zhou B, Nivollet S, Farr AG, Levin SD, Ziegler SF. Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction. J Immunol. 2002 Apr 01; 168(7):3288-94. PMID: 11907084.
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    25. Trobridge PA, Levin SD. Lck plays a critical role in Ca(2+) mobilization and CD28 costimulation in mature primary T cells. Eur J Immunol. 2001 Dec; 31(12):3567-79. PMID: 11745376.
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    26. Trobridge PA, Forbush KA, Levin SD. Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors. J Immunol. 2001 Jan 15; 166(2):809-18. PMID: 11145654.
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    27. Pandey A, Ozaki K, Baumann H, Levin SD, Puel A, Farr AG, Ziegler SF, Leonard WJ, Lodish HF. Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol. 2000 Jul; 1(1):59-64. PMID: 10881176.
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    28. Isaksen DE, Baumann H, Trobridge PA, Farr AG, Levin SD, Ziegler SF. Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction. J Immunol. 1999 Dec 01; 163(11):5971-7. PMID: 10570284.
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    29. Holdorf AD, Green JM, Levin SD, Denny MF, Straus DB, Link V, Changelian PS, Allen PM, Shaw AS. Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation. J Exp Med. 1999 Aug 02; 190(3):375-84. PMID: 10430626.
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    30. Levin SD, Koelling RM, Friend SL, Isaksen DE, Ziegler SF, Perlmutter RM, Farr AG. Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. J Immunol. 1999 Jan 15; 162(2):677-83. PMID: 9916685.
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    31. Alberola-Ila J, Levin SD, Barton G, Forbush K, Zon LI, Perlmutter RM. Analysis of the role of MKK-4/Sek-1 in T cell development and apoptosis. Int Immunol. 1998 Aug; 10(8):1077-82. PMID: 9723693.
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    32. Hashimoto K, Sohn SJ, Levin SD, Tada T, Perlmutter RM, Nakayama T. Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection. J Exp Med. 1996 Sep 01; 184(3):931-43. PMID: 9064353.
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    33. Ziegler SF, Levin SD, Johnson L, Copeland NG, Gilbert DJ, Jenkins NA, Baker E, Sutherland GR, Feldhaus AL, Ramsdell F. The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex. J Immunol. 1994 Feb 01; 152(3):1228-36. PMID: 8301128.
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    34. Anderson SJ, Levin SD, Perlmutter RM. Involvement of the protein tyrosine kinase p56lck in T cell signaling and thymocyte development. Adv Immunol. 1994; 56:151-78. PMID: 8073946.
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    35. Anderson SJ, Levin SD, Perlmutter RM. Protein tyrosine kinase p56lck controls allelic exclusion of T-cell receptor beta-chain genes. Nature. 1993 Oct 07; 365(6446):552-4. PMID: 8413611.
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    36. Levin SD, Abraham KM, Anderson SJ, Forbush KA, Perlmutter RM. The protein tyrosine kinase p56lck regulates thymocyte development independently of its interaction with CD4 and CD8 coreceptors [corrected]. J Exp Med. 1993 Jul 01; 178(1):245-55. PMID: 8391060.
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    37. Levin SD, Anderson SJ, Forbush KA, Perlmutter RM. A dominant-negative transgene defines a role for p56lck in thymopoiesis. EMBO J. 1993 Apr; 12(4):1671-80. PMID: 8385609.
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    38. Perlmutter RM, Levin SD, Appleby MW, Anderson SJ, Alberola-Ila J. Regulation of lymphocyte function by protein phosphorylation. Annu Rev Immunol. 1993; 11:451-99. PMID: 8476569.
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    39. Appleby MW, Gross JA, Cooke MP, Levin SD, Qian X, Perlmutter RM. Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell. 1992 Sep 04; 70(5):751-63. PMID: 1516132.
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    40. Hatakeyama M, Kono T, Kobayashi N, Kawahara A, Levin SD, Perlmutter RM, Taniguchi T. Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association. Science. 1991 Jun 14; 252(5012):1523-8. PMID: 2047859.
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    41. Abraham KM, Levin SD, Marth JD, Forbush KA, Perlmutter RM. Delayed thymocyte development induced by augmented expression of p56lck. J Exp Med. 1991 Jun 01; 173(6):1421-32. PMID: 1709675.
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    42. Abraham KM, Levin SD, Marth JD, Forbush KA, Perlmutter RM. Thymic tumorigenesis induced by overexpression of p56lck. Proc Natl Acad Sci U S A. 1991 May 01; 88(9):3977-81. PMID: 1708890.
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    43. Turner JM, Brodsky MH, Irving BA, Levin SD, Perlmutter RM, Littman DR. Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs. Cell. 1990 Mar 09; 60(5):755-65. PMID: 2107025.
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    44. Ziegler SF, Levin SD, Perlmutter RM. Transformation of NIH 3T3 fibroblasts by an activated form of p59hck. Mol Cell Biol. 1989 Jun; 9(6):2724-7. PMID: 2503711.
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    45. Grant FJ, Levin SD, Gilbert T, Kindsvogel W. Improved RNA sequencing method to determine immunoglobulin mRNA sequence. Nucleic Acids Res. 1987 Jul 10; 15(13):5496. PMID: 3601683.
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