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Steven Levin

TitleClinical Assistant Professor
InstitutionUniversity of Chicago
DepartmentOrthopaedic Surg & Rehab Med
AddressChicago IL 60637
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    R29AI042985     (LEVIN, STEVEN D)Apr 1, 1998 - Mar 31, 2003
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Murphy GS, Szokol JW, Avram MJ, Greenberg SB, Shear TD, Vender JS, Levin SD, Koh JL, Parikh KN, Patel SS. Effect of ventilation on cerebral oxygenation in patients undergoing surgery in the beach chair position: a randomized controlled trial. Br J Anaesth. 2014 Oct; 113(4):618-27. PMID: 24860157.
      Citations: 20     Fields:    Translation:Humans
    2. Levin SD, Wellman DS, Liu C, Li Y, Ren Y, Shah NA, Zhang LQ. Biomechanical strain characteristics of soft tissue biceps tenodesis and bony tenodesis. J Orthop Sci. 2013 Sep; 18(5):699-704. PMID: 23892426.
      Citations: 2     Fields:    Translation:Humans
    3. Koh JL, Levin SD, Chehab EL, Murphy GS. Neer Award 2012: cerebral oxygenation in the beach chair position: a prospective study on the effect of general anesthesia compared with regional anesthesia and sedation. J Shoulder Elbow Surg. 2013 Oct; 22(10):1325-31. PMID: 23571083.
      Citations: 22     Fields:    Translation:Humans
    4. Song X, Zhu S, Shi P, Liu Y, Shi Y, Levin SD, Qian Y. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat Immunol. 2011 Oct 12; 12(12):1151-8. PMID: 21993849.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    5. Wojno ED, Hosken N, Stumhofer JS, O'Hara AC, Mauldin E, Fang Q, Turka LA, Levin SD, Hunter CA. A role for IL-27 in limiting T regulatory cell populations. J Immunol. 2011 Jul 01; 187(1):266-73. PMID: 21622862; PMCID: PMC3119737.
      Citations: 46     Fields:    Translation:AnimalsCells
    6. Levin SD, Taft DW, Brandt CS, Bucher C, Howard ED, Chadwick EM, Johnston J, Hammond A, Bontadelli K, Ardourel D, Hebb L, Wolf A, Bukowski TR, Rixon MW, Kuijper JL, Ostrander CD, West JW, Bilsborough J, Fox B, Gao Z, Xu W, Ramsdell F, Blazar BR, Lewis KE. Vstm3 is a member of the CD28 family and an important modulator of T-cell function. Eur J Immunol. 2011 Apr; 41(4):902-15. PMID: 21416464; PMCID: PMC3733993.
      Citations: 153     Fields:    Translation:HumansAnimalsCells
    7. Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK. Cutting edge: TIGIT has T cell-intrinsic inhibitory functions. J Immunol. 2011 Feb 01; 186(3):1338-42. PMID: 21199897; PMCID: PMC3128994.
      Citations: 248     Fields:    Translation:AnimalsCells
    8. Stumhofer JS, Tait ED, Quinn WJ, Hosken N, Goenka R, Fielding CA, O'Hara AC, Chen Y, Jones ML, Saris CJ, Rose-John S, Cua DJ, Jones SA, Elloso MM, Cancro MP, Levin SD, Hunter CA, Spudy B, Grötzinger J. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol. 2010 Dec; 11(12):1119-26. PMID: 21057510; PMCID: PMC3059498.
      Citations: 91     Fields:    Translation:AnimalsCells
    9. Khan N, Levin SD, Domont ZB, Wu YN, Ren Y, Zhang LQ. Strain effects of placing an arthroscopic portal through the subscapularis tendon. J Shoulder Elbow Surg. 2011 Jan; 20(1):33-8. PMID: 21051243.
      Citations: 1     Fields:    Translation:Humans
    10. Kemp KL, Levin SD, Stein PL. Lck regulates IL-10 expression in memory-like Th1 cells. Eur J Immunol. 2010 Nov; 40(11):3210-9. PMID: 21061443; PMCID: PMC3517127.
      Citations: 7     Fields:    Translation:AnimalsCells
    11. Wellman DS, McCoy BW, Levin SD, Knight BP. Shoulder arthroscopy in patients with a cardiac pacemaker or defibrillator: a case report and discussion of perioperative management. J Shoulder Elbow Surg. 2010 Dec; 19(8):1204-9. PMID: 20656525.
      Citations: 1     Fields:    Translation:Humans
    12. Kemp KL, Levin SD, Bryce PJ, Stein PL. Lck mediates Th2 differentiation through effects on T-bet and GATA-3. J Immunol. 2010 Apr 15; 184(8):4178-84. PMID: 20237292; PMCID: PMC4889130.
      Citations: 19     Fields:    Translation:AnimalsCells
    13. Mabry R, Lewis KE, Moore M, McKernan PA, Bukowski TR, Bontadelli K, Brender T, Okada S, Lum K, West J, Kuijper JL, Ardourel D, Franke S, Lockwood L, Vu T, Frank A, Appleby MW, Wolf A, Reardon B, Hamacher NB, Stevens B, Lewis P, Lewis KB, Gilbertson DG, Lantry M, Julien SH, Ostrander C, Chan C, Byrnes-Blake K, Brody J, Presnell S, Meengs B, Levin SD, Snavely M. Engineering of stable bispecific antibodies targeting IL-17A and IL-23. Protein Eng Des Sel. 2010 Mar; 23(3):115-27. PMID: 20022918.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    14. Levin SD. IL-17 receptor signaling: ubiquitin gets in on the act. Sci Signal. 2009 Oct 13; 2(92):pe64. PMID: 19825826.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    15. Brandt CS, Baratin M, Yi EC, Kennedy J, Gao Z, Fox B, Haldeman B, Ostrander CD, Kaifu T, Chabannon C, Moretta A, West R, Xu W, Vivier E, Levin SD. The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med. 2009 Jul 06; 206(7):1495-503. PMID: 19528259; PMCID: PMC2715080.
      Citations: 329     Fields:    Translation:HumansAnimalsCells
    16. Yang S, Park HS, Flores S, Levin SD, Makhsous M, Lin F, Koh J, Nuber G, Zhang LQ. Biomechanical analysis of bursal-sided partial thickness rotator cuff tears. J Shoulder Elbow Surg. 2009 May-Jun; 18(3):379-85. PMID: 19269860.
      Citations: 15     Fields:    Translation:Humans
    17. Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, Harder B, Okada S, Ostrander CD, Kreindler JL, Aujla SJ, Reardon B, Moore M, Shea P, Schreckhise R, Bukowski TR, Presnell S, Guerra-Lewis P, Parrish-Novak J, Ellsworth JL, Jaspers S, Lewis KE, Appleby M, Kolls JK, Rixon M, West JW, Gao Z, Levin SD. Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol. 2007 Oct 15; 179(8):5462-73. PMID: 17911633; PMCID: PMC2849293.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    18. Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, Haugen HS, Maurer M, Harder B, Johnston J, Bort S, Mudri S, Kuijper JL, Bukowski T, Shea P, Dong DL, Dasovich M, Grant FJ, Lockwood L, Levin SD, LeCiel C, Waggie K, Day H, Topouzis S, Kramer J, Kuestner R, Chen Z, Foster D, Parrish-Novak J, Gross JA. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol. 2004 Jul; 5(7):752-60. PMID: 15184896.
      Citations: 296     Fields:    Translation:HumansAnimalsCells
    19. Yu XZ, Levin SD, Madrenas J, Anasetti C. Lck is required for activation-induced T cell death after TCR ligation with partial agonists. J Immunol. 2004 Feb 01; 172(3):1437-43. PMID: 14734719.
      Citations: 8     Fields:    Translation:AnimalsCells
    20. Sicinska E, Aifantis I, Le Cam L, Swat W, Borowski C, Yu Q, Ferrando AA, Levin SD, Geng Y, von Boehmer H, Sicinski P. Requirement for cyclin D3 in lymphocyte development and T cell leukemias. Cancer Cell. 2003 Dec; 4(6):451-61. PMID: 14706337.
      Citations: 160     Fields:    Translation:HumansAnimalsCells
    21. Soller BR, Idwasi PO, Balaguer J, Levin S, Simsir SA, Vander Salm TJ, Collette H, Heard SO. Noninvasive, near infrared spectroscopic-measured muscle pH and PO2 indicate tissue perfusion for cardiac surgical patients undergoing cardiopulmonary bypass. Crit Care Med. 2003 Sep; 31(9):2324-31. PMID: 14501963.
      Citations: 8     Fields:    Translation:Humans
    22. Filipp D, Zhang J, Leung BL, Shaw A, Levin SD, Veillette A, Julius M. Regulation of Fyn through translocation of activated Lck into lipid rafts. J Exp Med. 2003 May 05; 197(9):1221-7. PMID: 12732664; PMCID: PMC2193969.
      Citations: 46     Fields:    Translation:AnimalsCells
    23. Huang J, Lo PF, Zal T, Gascoigne NR, Smith BA, Levin SD, Grey HM. CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9369-73. PMID: 12077322; PMCID: PMC123147.
      Citations: 64     Fields:    Translation:AnimalsCells
    24. Isaksen DE, Baumann H, Zhou B, Nivollet S, Farr AG, Levin SD, Ziegler SF. Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction. J Immunol. 2002 Apr 01; 168(7):3288-94. PMID: 11907084.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    25. Trobridge PA, Levin SD. Lck plays a critical role in Ca(2+) mobilization and CD28 costimulation in mature primary T cells. Eur J Immunol. 2001 Dec; 31(12):3567-79. PMID: 11745376.
      Citations: 15     Fields:    Translation:AnimalsCells
    26. Trobridge PA, Forbush KA, Levin SD. Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors. J Immunol. 2001 Jan 15; 166(2):809-18. PMID: 11145654.
      Citations: 9     Fields:    Translation:AnimalsCells
    27. Pandey A, Ozaki K, Baumann H, Levin SD, Puel A, Farr AG, Ziegler SF, Leonard WJ, Lodish HF. Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol. 2000 Jul; 1(1):59-64. PMID: 10881176.
      Citations: 178     Fields:    Translation:Cells
    28. Isaksen DE, Baumann H, Trobridge PA, Farr AG, Levin SD, Ziegler SF. Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction. J Immunol. 1999 Dec 01; 163(11):5971-7. PMID: 10570284.
      Citations: 72     Fields:    Translation:Cells
    29. Holdorf AD, Green JM, Levin SD, Denny MF, Straus DB, Link V, Changelian PS, Allen PM, Shaw AS. Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation. J Exp Med. 1999 Aug 02; 190(3):375-84. PMID: 10430626; PMCID: PMC2195584.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    30. Levin SD, Koelling RM, Friend SL, Isaksen DE, Ziegler SF, Perlmutter RM, Farr AG. Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. J Immunol. 1999 Jan 15; 162(2):677-83. PMID: 9916685.
      Citations: 94     Fields:    Translation:AnimalsCells
    31. Alberola-Ila J, Levin SD, Barton G, Forbush K, Zon LI, Perlmutter RM. Analysis of the role of MKK-4/Sek-1 in T cell development and apoptosis. Int Immunol. 1998 Aug; 10(8):1077-82. PMID: 9723693.
      Citations: 1     Fields:    Translation:AnimalsCells
    32. Hashimoto K, Sohn SJ, Levin SD, Tada T, Perlmutter RM, Nakayama T. Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection. J Exp Med. 1996 Sep 01; 184(3):931-43. PMID: 9064353; PMCID: PMC2192768.
      Citations: 14     Fields:    Translation:AnimalsCells
    33. Ziegler SF, Levin SD, Johnson L, Copeland NG, Gilbert DJ, Jenkins NA, Baker E, Sutherland GR, Feldhaus AL, Ramsdell F. The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex. J Immunol. 1994 Feb 01; 152(3):1228-36. PMID: 8301128.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    34. Anderson SJ, Levin SD, Perlmutter RM. Involvement of the protein tyrosine kinase p56lck in T cell signaling and thymocyte development. Adv Immunol. 1994; 56:151-78. PMID: 8073946.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    35. Anderson SJ, Levin SD, Perlmutter RM. Protein tyrosine kinase p56lck controls allelic exclusion of T-cell receptor beta-chain genes. Nature. 1993 Oct 07; 365(6446):552-4. PMID: 8413611.
      Citations: 28     Fields:    Translation:AnimalsCells
    36. Levin SD, Abraham KM, Anderson SJ, Forbush KA, Perlmutter RM. The protein tyrosine kinase p56lck regulates thymocyte development independently of its interaction with CD4 and CD8 coreceptors [corrected]. J Exp Med. 1993 Jul 01; 178(1):245-55. PMID: 8391060; PMCID: PMC2191071.
      Citations: 9     Fields:    Translation:AnimalsCells
    37. Levin SD, Anderson SJ, Forbush KA, Perlmutter RM. A dominant-negative transgene defines a role for p56lck in thymopoiesis. EMBO J. 1993 Apr; 12(4):1671-80. PMID: 8385609; PMCID: PMC413381.
      Citations: 59     Fields:    Translation:AnimalsCells
    38. Perlmutter RM, Levin SD, Appleby MW, Anderson SJ, Alberola-Ila J. Regulation of lymphocyte function by protein phosphorylation. Annu Rev Immunol. 1993; 11:451-99. PMID: 8476569.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    39. Appleby MW, Gross JA, Cooke MP, Levin SD, Qian X, Perlmutter RM. Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell. 1992 Sep 04; 70(5):751-63. PMID: 1516132.
      Citations: 133     Fields:    Translation:AnimalsCells
    40. Hatakeyama M, Kono T, Kobayashi N, Kawahara A, Levin SD, Perlmutter RM, Taniguchi T. Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association. Science. 1991 Jun 14; 252(5012):1523-8. PMID: 2047859.
      Citations: 148     Fields:    Translation:HumansAnimalsCells
    41. Abraham KM, Levin SD, Marth JD, Forbush KA, Perlmutter RM. Delayed thymocyte development induced by augmented expression of p56lck. J Exp Med. 1991 Jun 01; 173(6):1421-32. PMID: 1709675; PMCID: PMC2190838.
      Citations: 23     Fields:    Translation:AnimalsCells
    42. Abraham KM, Levin SD, Marth JD, Forbush KA, Perlmutter RM. Thymic tumorigenesis induced by overexpression of p56lck. Proc Natl Acad Sci U S A. 1991 May 01; 88(9):3977-81. PMID: 1708890; PMCID: PMC51576.
      Citations: 48     Fields:    Translation:AnimalsCells
    43. Turner JM, Brodsky MH, Irving BA, Levin SD, Perlmutter RM, Littman DR. Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs. Cell. 1990 Mar 09; 60(5):755-65. PMID: 2107025.
      Citations: 188     Fields:    Translation:AnimalsCells
    44. Ziegler SF, Levin SD, Perlmutter RM. Transformation of NIH 3T3 fibroblasts by an activated form of p59hck. Mol Cell Biol. 1989 Jun; 9(6):2724-7. PMID: 2503711; PMCID: PMC362345.
      Citations: 15     Fields:    Translation:AnimalsCells
    45. Grant FJ, Levin SD, Gilbert T, Kindsvogel W. Improved RNA sequencing method to determine immunoglobulin mRNA sequence. Nucleic Acids Res. 1987 Jul 10; 15(13):5496. PMID: 3601683; PMCID: PMC305991.
      Citations:    Fields:    Translation:AnimalsCells
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