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Dorothy Hanck to Ion Channel Gating

This is a "connection" page, showing publications Dorothy Hanck has written about Ion Channel Gating.

 
Connection Strength
 
 
 
4.774
 
  1. Sheets MF, Chen T, Hanck DA. Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. Pflugers Arch. 2011 Jan; 461(1):91-7.
    View in: PubMed
    Score: 0.370
  2. Hanck DA, Nikitina E, McNulty MM, Fozzard HA, Lipkind GM, Sheets MF. Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circ Res. 2009 Aug 28; 105(5):492-9.
    View in: PubMed
    Score: 0.340
  3. Edgerton GB, Blumenthal KM, Hanck DA. Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5. Toxicon. 2008 Sep 01; 52(3):489-500.
    View in: PubMed
    Score: 0.315
  4. Bittner KC, Hanck DA. The relationship between single-channel and whole-cell conductance in the T-type Ca2+ channel CaV3.1. Biophys J. 2008 Jul; 95(2):931-41.
    View in: PubMed
    Score: 0.309
  5. Sheets MF, Hanck DA. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. J Physiol. 2007 Jul 01; 582(Pt 1):317-34.
    View in: PubMed
    Score: 0.291
  6. Hanck DA, Sheets MF. Site-3 toxins and cardiac sodium channels. Toxicon. 2007 Feb; 49(2):181-93.
    View in: PubMed
    Score: 0.279
  7. McNulty MM, Kyle JW, Lipkind GM, Hanck DA. An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels. Mol Pharmacol. 2006 Nov; 70(5):1514-23.
    View in: PubMed
    Score: 0.276
  8. Lam AD, Chikina MD, McNulty MM, Glaaser IW, Hanck DA. Role of Domain IV/S4 outermost arginines in gating of T-type calcium channels. Pflugers Arch. 2005 Nov; 451(2):349-61.
    View in: PubMed
    Score: 0.259
  9. Sheets MF, Hanck DA. Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation. J Physiol. 2005 Feb 15; 563(Pt 1):83-93.
    View in: PubMed
    Score: 0.246
  10. Puljung MC, Berthoud VM, Beyer EC, Hanck DA. Polyvalent cations constitute the voltage gating particle in human connexin37 hemichannels. J Gen Physiol. 2004 Nov; 124(5):587-603.
    View in: PubMed
    Score: 0.244
  11. Sheets MF, Kyle JW, Hanck DA. The role of the putative inactivation lid in sodium channel gating current immobilization. J Gen Physiol. 2000 May; 115(5):609-20.
    View in: PubMed
    Score: 0.179
  12. Hanck DA, Makielski JC, Sheets MF. Lidocaine alters activation gating of cardiac Na channels. Pflugers Arch. 2000 Apr; 439(6):814-21.
    View in: PubMed
    Score: 0.178
  13. Sheets MF, Hanck DA. Gating of skeletal and cardiac muscle sodium channels in mammalian cells. J Physiol. 1999 Jan 15; 514 ( Pt 2):425-36.
    View in: PubMed
    Score: 0.164
  14. Millonas MM, Hanck DA. Nonequilibrium response spectroscopy of voltage-sensitive ion channel gating. Biophys J. 1998 Jan; 74(1):210-29.
    View in: PubMed
    Score: 0.152
  15. Sheets MF, Kyle JW, Krueger S, Hanck DA. Optimization of a mammalian expression system for the measurement of sodium channel gating currents. Am J Physiol. 1996 Sep; 271(3 Pt 1):C1001-6.
    View in: PubMed
    Score: 0.139
  16. Hanck DA, Sheets MF. Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin. J Gen Physiol. 1995 Oct; 106(4):601-16.
    View in: PubMed
    Score: 0.130
  17. Sheets MF, Hanck DA. Voltage-dependent open-state inactivation of cardiac sodium channels: gating current studies with Anthopleurin-A toxin. J Gen Physiol. 1995 Oct; 106(4):617-40.
    View in: PubMed
    Score: 0.130
  18. Hanck DA, Makielski JC, Sheets MF. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J Gen Physiol. 1994 Jan; 103(1):19-43.
    View in: PubMed
    Score: 0.115
  19. Hanck DA, Sheets MF, Fozzard HA. Gating currents associated with Na channels in canine cardiac Purkinje cells. J Gen Physiol. 1990 Mar; 95(3):439-57.
    View in: PubMed
    Score: 0.088
  20. Sheets MF, Fozzard HA, Lipkind GM, Hanck DA. Sodium channel molecular conformations and antiarrhythmic drug affinity. Trends Cardiovasc Med. 2010 Jan; 20(1):16-21.
    View in: PubMed
    Score: 0.087
  21. McNulty MM, Edgerton GB, Shah RD, Hanck DA, Fozzard HA, Lipkind GM. Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. J Physiol. 2007 Jun 01; 581(Pt 2):741-55.
    View in: PubMed
    Score: 0.072
  22. Khan A, Kyle JW, Hanck DA, Lipkind GM, Fozzard HA. Isoform-dependent interaction of voltage-gated sodium channels with protons. J Physiol. 2006 Oct 15; 576(Pt 2):493-501.
    View in: PubMed
    Score: 0.069
  23. Freeze BS, McNulty MM, Hanck DA. State-dependent verapamil block of the cloned human Ca(v)3.1 T-type Ca(2+) channel. Mol Pharmacol. 2006 Aug; 70(2):718-26.
    View in: PubMed
    Score: 0.068
  24. Sheets MF, Hanck DA. Molecular action of lidocaine on the voltage sensors of sodium channels. J Gen Physiol. 2003 Feb; 121(2):163-75.
    View in: PubMed
    Score: 0.054
  25. Sheets MF, Hanck DA. The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels. Biophys J. 2002 Jun; 82(6):3048-55.
    View in: PubMed
    Score: 0.052
  26. Sheets MF, Kyle JW, Kallen RG, Hanck DA. The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophys J. 1999 Aug; 77(2):747-57.
    View in: PubMed
    Score: 0.042
  27. Richard Benzinger G, Tonkovich GS, Hanck DA. Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents. J Gen Physiol. 1999 Feb; 113(2):333-46.
    View in: PubMed
    Score: 0.041
  28. Hanck D. Heartthrobs. Science. 1998 Feb 13; 279(5353):1004.
    View in: PubMed
    Score: 0.038
  29. Kyle JW, Minogue PJ, Thomas BC, Domowicz DA, Berthoud VM, Hanck DA, Beyer EC. An intact connexin N-terminus is required for function but not gap junction formation. J Cell Sci. 2008 Aug 15; 121(Pt 16):2744-50.
    View in: PubMed
    Score: 0.020
  30. Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel. Biochemistry. 1996 Nov 12; 35(45):14157-64.
    View in: PubMed
    Score: 0.009
  31. Dias-Kadambi BL, Combs KA, Drum CL, Hanck DA, Blumenthal KM. The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B. J Biol Chem. 1996 Sep 27; 271(39):23828-35.
    View in: PubMed
    Score: 0.009
  32. Lipkind GM, Hanck DA, Fozzard HA. A structural motif for the voltage-gated potassium channel pore. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9215-9.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.