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Connection

Amittha Wickrema to Signal Transduction

This is a "connection" page, showing publications Amittha Wickrema has written about Signal Transduction.
Connection Strength

0.854
  1. Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks. Clin Cancer Res. 2019 09 15; 25(18):5638-5649.
    View in: PubMed
    Score: 0.313
  2. Regulation of myeloma cell growth through Akt/Gsk3/forkhead signaling pathway. Biochem Biophys Res Commun. 2002 Oct 04; 297(4):760-4.
    View in: PubMed
    Score: 0.098
  3. Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors. Biochem Biophys Res Commun. 2000 Aug 18; 275(1):16-9.
    View in: PubMed
    Score: 0.084
  4. Engagement of Gab1 and Gab2 in erythropoietin signaling. J Biol Chem. 1999 Aug 27; 274(35):24469-74.
    View in: PubMed
    Score: 0.079
  5. IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells. Blood. 2015 May 14; 125(20):3144-52.
    View in: PubMed
    Score: 0.058
  6. Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursors. J Biol Chem. 2013 Aug 16; 288(33):23814-22.
    View in: PubMed
    Score: 0.051
  7. Distinct functions of erythropoietin and stem cell factor are linked to activation of mTOR kinase signaling pathway in human erythroid progenitors. Cytokine. 2013 Jan; 61(1):329-35.
    View in: PubMed
    Score: 0.049
  8. Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells. Oncogene. 2002 Feb 28; 21(10):1556-62.
    View in: PubMed
    Score: 0.023
  9. Phosphatase inhibition promotes antiapoptotic but not proliferative signaling pathways in erythropoietin-dependent HCD57 cells. Blood. 2000 Sep 15; 96(6):2084-92.
    View in: PubMed
    Score: 0.021
  10. Defective expression of the SHP-1 phosphatase in polycythemia vera. Exp Hematol. 1999 Jul; 27(7):1124-32.
    View in: PubMed
    Score: 0.019
  11. Protein kinase B (c-Akt), phosphatidylinositol 3-kinase, and STAT5 are activated by erythropoietin (EPO) in HCD57 erythroid cells but are constitutively active in an EPO-independent, apoptosis-resistant subclone (HCD57-SREI cells). Blood. 1999 Jun 01; 93(11):3757-73.
    View in: PubMed
    Score: 0.019
  12. P. falciparum modulates erythroblast cell gene expression in signaling and erythrocyte production pathways. PLoS One. 2011 May 04; 6(5):e19307.
    View in: PubMed
    Score: 0.011
  13. Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase. Cancer Res. 2011 Feb 01; 71(3):955-63.
    View in: PubMed
    Score: 0.011
  14. Tumor necrosis factor-alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia. Blood. 2003 Jan 15; 101(2):524-31.
    View in: PubMed
    Score: 0.006
  15. Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis. J Biol Chem. 2002 Mar 08; 277(10):7726-35.
    View in: PubMed
    Score: 0.006
  16. CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors. Exp Hematol. 1999 Aug; 27(8):1315-21.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.