Le Shen to Tight Junctions
This is a "connection" page, showing publications Le Shen has written about Tight Junctions.
Connection Strength
4.015
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The role of molecular remodeling in differential regulation of tight junction permeability. Semin Cell Dev Biol. 2014 Dec; 36:204-12.
Score: 0.431
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Tight junctions on the move: molecular mechanisms for epithelial barrier regulation. Ann N Y Acad Sci. 2012 Jul; 1258:9-18.
Score: 0.369
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Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol. 2011; 73:283-309.
Score: 0.333
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The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. J Cell Biol. 2008 May 19; 181(4):683-95.
Score: 0.277
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Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J Cell Sci. 2006 May 15; 119(Pt 10):2095-106.
Score: 0.240
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Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. Am J Physiol Gastrointest Liver Physiol. 2006 Apr; 290(4):G577-82.
Score: 0.239
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Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis. Mol Biol Cell. 2005 Sep; 16(9):3919-36.
Score: 0.226
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Molecular mechanism of claudin-15 strand flexibility: A computational study. J Gen Physiol. 2022 12 05; 154(12).
Score: 0.189
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Idiopathic pulmonary fibrosis is associated with tight junction protein alterations. Biochim Biophys Acta Biomembr. 2020 05 01; 1862(5):183205.
Score: 0.156
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Computational Modeling of Claudin Structure and Function. Int J Mol Sci. 2020 Jan 23; 21(3).
Score: 0.156
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Cerebral Cavernous Malformation Proteins in Barrier Maintenance and Regulation. Int J Mol Sci. 2020 Jan 20; 21(2).
Score: 0.156
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Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice. Biochim Biophys Acta. 2016 Apr; 1860(4):765-74.
Score: 0.117
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Claudin-2-dependent paracellular channels are dynamically gated. Elife. 2015 Nov 14; 4:e09906.
Score: 0.116
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Microtubules are required for efficient epithelial tight junction homeostasis and restoration. Am J Physiol Cell Physiol. 2014 Aug 01; 307(3):C245-54.
Score: 0.106
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Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. Mol Biol Cell. 2013 Oct; 24(19):3056-68.
Score: 0.100
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TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 2013 Aug; 145(2):407-15.
Score: 0.098
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Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. J Cell Biol. 2011 May 02; 193(3):565-82.
Score: 0.085
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The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology. 2011 Apr; 140(4):1208-1218.e1-2.
Score: 0.083
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MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8237-41.
Score: 0.079
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Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J Cell Biol. 2010 Apr 05; 189(1):111-26.
Score: 0.079
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Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol Biol Cell. 2010 Apr 01; 21(7):1200-13.
Score: 0.078
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Mechanisms and functional implications of intestinal barrier defects. Dig Dis. 2009; 27(4):443-9.
Score: 0.077
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No static at all. Ann N Y Acad Sci. 2009 May; 1165:314-22.
Score: 0.074
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Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology. 2009 Feb; 136(2):551-63.
Score: 0.072
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IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance. Cell Host Microbe. 2017 Jun 14; 21(6):671-681.e4.
Score: 0.032
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Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. J Biol Chem. 2010 Apr 16; 285(16):12037-46.
Score: 0.020
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LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology. 2007 Jun; 132(7):2383-94.
Score: 0.016
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A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest. 2004 Mar; 84(3):282-91.
Score: 0.013