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Le Shen

Concepts (372)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tight Junctions
28
2022
153
3.750
Why?
Intestinal Mucosa
24
2020
825
2.440
Why?
Hemangioma, Cavernous, Central Nervous System
9
2022
259
1.820
Why?
Epithelium
8
2020
326
1.210
Why?
Epithelial Cells
13
2019
710
1.200
Why?
Occludin
16
2020
66
0.970
Why?
Endocytosis
8
2013
186
0.850
Why?
Membrane Proteins
16
2019
1276
0.830
Why?
Myosin-Light-Chain Kinase
11
2013
41
0.800
Why?
Claudins
8
2022
34
0.730
Why?
Zonula Occludens-1 Protein
12
2020
70
0.710
Why?
KRIT1 Protein
4
2022
62
0.700
Why?
Cell Membrane Permeability
5
2018
121
0.690
Why?
Myosin Type II
3
2018
50
0.630
Why?
rho-Associated Kinases
5
2018
162
0.620
Why?
Signal Transduction
13
2021
3586
0.590
Why?
Apoptosis
6
2021
1763
0.530
Why?
Colon
6
2025
541
0.520
Why?
Caco-2 Cells
13
2019
125
0.450
Why?
Actins
7
2018
473
0.410
Why?
Animals
43
2025
28945
0.410
Why?
Apoptosis Regulatory Proteins
5
2020
204
0.390
Why?
Tumor Necrosis Factor-alpha
8
2020
713
0.380
Why?
Phosphoproteins
8
2012
263
0.360
Why?
Mice
27
2025
12562
0.340
Why?
Paneth Cells
1
2020
10
0.330
Why?
Permeability
9
2015
144
0.320
Why?
Myosin Light Chains
5
2013
29
0.320
Why?
Stem Cell Niche
1
2020
24
0.320
Why?
Colitis
5
2019
262
0.320
Why?
Arginine
1
2020
144
0.320
Why?
Gastric Mucosa
1
2009
70
0.290
Why?
Adherens Junctions
1
2008
35
0.290
Why?
Intestine, Small
1
2020
310
0.280
Why?
Claudin-2
3
2017
10
0.280
Why?
Intestines
4
2020
431
0.270
Why?
Stem Cells
1
2020
394
0.270
Why?
Cadherins
1
2008
180
0.270
Why?
MicroRNAs
2
2022
592
0.260
Why?
Drug Resistance, Neoplasm
2
2021
647
0.260
Why?
Inflammatory Bowel Diseases
6
2025
647
0.260
Why?
Organoids
2
2022
78
0.260
Why?
Endothelium
2
2020
60
0.260
Why?
Transcriptome
2
2025
770
0.260
Why?
Caveolae
2
2007
6
0.250
Why?
Phosphorylation
7
2018
1157
0.250
Why?
Humans
41
2025
96127
0.240
Why?
Enterocolitis
1
2006
13
0.240
Why?
Mice, Inbred C57BL
12
2020
3490
0.240
Why?
Models, Biological
6
2020
1815
0.230
Why?
Protein-Arginine N-Methyltransferases
1
2025
22
0.220
Why?
Disease Models, Animal
9
2020
2551
0.220
Why?
Carcinoma, Adenoid Cystic
1
2025
43
0.220
Why?
Povidone-Iodine
1
2024
9
0.220
Why?
Microvilli
2
2018
44
0.220
Why?
Anti-Infective Agents, Local
1
2024
25
0.210
Why?
Colonic Pouches
1
2025
97
0.210
Why?
Proctocolectomy, Restorative
1
2025
115
0.210
Why?
Salivary Gland Neoplasms
1
2025
81
0.210
Why?
Recombinant Fusion Proteins
1
2005
564
0.200
Why?
Mice, Transgenic
10
2019
1645
0.200
Why?
Actin Cytoskeleton
5
2018
201
0.190
Why?
Dogs
5
2015
719
0.190
Why?
Circulating MicroRNA
1
2022
14
0.190
Why?
Cell Membrane
3
2018
696
0.180
Why?
Cell Line
8
2015
2533
0.180
Why?
Mebendazole
1
2021
8
0.180
Why?
Antinematodal Agents
1
2021
9
0.180
Why?
Sodium-Potassium-Chloride Symporters
2
2012
22
0.170
Why?
Claudin-1
4
2011
17
0.170
Why?
Brain
4
2020
2482
0.170
Why?
Eukaryotic Initiation Factor-4A
1
2020
3
0.170
Why?
Sterols
1
2020
19
0.170
Why?
5' Untranslated Regions
1
2020
54
0.170
Why?
Colitis, Ulcerative
2
2025
801
0.160
Why?
MAP Kinase Kinase Kinase 3
1
2020
13
0.160
Why?
Atrioventricular Node
1
2020
36
0.160
Why?
Hemangioma, Cavernous
1
2020
69
0.160
Why?
Plasma Cells
1
2020
88
0.160
Why?
Homeostasis
2
2020
467
0.150
Why?
rhoA GTP-Binding Protein
1
2020
88
0.150
Why?
Molecular Dynamics Simulation
2
2020
308
0.150
Why?
Caspase 3
1
2019
164
0.150
Why?
Autoantigens
1
2020
139
0.150
Why?
Sarcoplasmic Reticulum Calcium-Transporting ATPases
1
2019
30
0.150
Why?
Cisplatin
1
2021
611
0.150
Why?
Autoantibodies
1
2020
281
0.150
Why?
Mutant Proteins
1
2019
99
0.150
Why?
Calcium
3
2019
1205
0.140
Why?
Up-Regulation
3
2017
741
0.140
Why?
Central Nervous System Neoplasms
1
2019
99
0.140
Why?
Cholesterol
2
2014
370
0.140
Why?
Ion Channels
1
2020
260
0.140
Why?
Actomyosin
1
2018
47
0.140
Why?
Mice, Knockout
7
2019
2163
0.140
Why?
T-Box Domain Proteins
1
2019
128
0.140
Why?
Gastrointestinal Tract
1
2019
197
0.140
Why?
ATP-Binding Cassette Transporters
1
2018
142
0.140
Why?
Heart Rate
1
2020
519
0.130
Why?
Enterobacteriaceae Infections
1
2017
25
0.130
Why?
Idiopathic Pulmonary Fibrosis
1
2020
210
0.130
Why?
Interleukins
1
2017
134
0.130
Why?
Cytoskeleton
2
2008
200
0.120
Why?
Microtubules
2
2014
134
0.120
Why?
Diarrhea
1
2017
181
0.120
Why?
Gastrointestinal Microbiome
2
2020
590
0.120
Why?
Proto-Oncogene Proteins
1
2019
684
0.120
Why?
X-Ray Microtomography
1
2016
102
0.120
Why?
Mycobacterium tuberculosis
1
2018
208
0.120
Why?
Cell Line, Tumor
5
2025
2794
0.120
Why?
Cell Proliferation
3
2025
1761
0.120
Why?
Enterovirus B, Human
1
2015
9
0.110
Why?
CD55 Antigens
1
2015
21
0.110
Why?
Enterovirus Infections
1
2015
31
0.110
Why?
Protein Transport
4
2014
439
0.110
Why?
Disease Progression
1
2019
1568
0.110
Why?
Biological Transport
1
2015
412
0.110
Why?
Ovarian Neoplasms
1
2021
828
0.110
Why?
Sterol Regulatory Element Binding Protein 2
1
2014
5
0.110
Why?
Atrial Fibrillation
1
2019
392
0.110
Why?
Disease Susceptibility
1
2015
220
0.100
Why?
Protein Binding
6
2018
1561
0.100
Why?
Liver Diseases
1
2015
249
0.100
Why?
Dextran Sulfate
3
2019
70
0.100
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2013
19
0.100
Why?
Microscopy, Fluorescence
4
2010
444
0.100
Why?
Receptors, Tumor Necrosis Factor, Type I
1
2013
43
0.100
Why?
Ethanol
1
2015
270
0.100
Why?
Caveolin 1
2
2010
25
0.100
Why?
Capsaicin
1
2012
45
0.100
Why?
TRPV Cation Channels
1
2012
16
0.100
Why?
Casein Kinase II
1
2012
11
0.100
Why?
Chlorides
1
2012
108
0.090
Why?
Lymphatic Vessels
1
2013
70
0.090
Why?
Real-Time Polymerase Chain Reaction
3
2022
299
0.090
Why?
Endothelial Cells
3
2020
482
0.090
Why?
Bridged Bicyclo Compounds, Heterocyclic
3
2012
103
0.090
Why?
Xenograft Model Antitumor Assays
2
2025
535
0.090
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2012
111
0.090
Why?
Lung
2
2020
1382
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
3
2022
898
0.080
Why?
Protein Kinase C
2
2008
267
0.080
Why?
Wound Healing
2
2021
378
0.080
Why?
Protein Interaction Domains and Motifs
1
2011
91
0.080
Why?
Immunity, Innate
2
2017
464
0.080
Why?
Interferon-gamma
3
2008
467
0.080
Why?
Antineoplastic Agents
1
2021
2422
0.080
Why?
T-Lymphocyte Subsets
1
2012
290
0.080
Why?
Dynamin II
2
2011
15
0.080
Why?
Myosin Heavy Chains
2
2020
91
0.080
Why?
Interleukin-13
1
2010
42
0.080
Why?
Clathrin
1
2009
32
0.080
Why?
Tetradecanoylphorbol Acetate
1
2009
133
0.080
Why?
Wnt Signaling Pathway
1
2020
103
0.080
Why?
Binding Sites
3
2018
1167
0.070
Why?
cdc42 GTP-Binding Protein
1
2008
12
0.070
Why?
Microscopy, Electron
2
2022
510
0.070
Why?
Immunity, Mucosal
1
2009
72
0.070
Why?
Fluorescence Recovery After Photobleaching
1
2008
13
0.070
Why?
Immunohistochemistry
4
2015
1829
0.070
Why?
Sodium-Hydrogen Exchangers
1
2008
78
0.070
Why?
Diffusion
1
2008
95
0.070
Why?
Thiazolidines
2
2005
18
0.070
Why?
Case-Control Studies
2
2025
1958
0.070
Why?
Organ Specificity
1
2009
285
0.070
Why?
Intracellular Signaling Peptides and Proteins
3
2018
396
0.070
Why?
DNA Primers
2
2022
548
0.070
Why?
Multiprotein Complexes
1
2008
108
0.070
Why?
Cell Polarity
1
2008
119
0.070
Why?
Acute Disease
2
2020
872
0.070
Why?
Tumor Necrosis Factor Ligand Superfamily Member 14
1
2007
14
0.070
Why?
Thiazoles
2
2005
130
0.070
Why?
Bacterial Infections
1
2009
185
0.070
Why?
Serotonin
1
2008
219
0.070
Why?
Time Factors
4
2024
5585
0.070
Why?
Myocytes, Cardiac
2
2020
324
0.060
Why?
Female
8
2025
50063
0.060
Why?
Claudin-4
2
2020
8
0.060
Why?
Enzyme Induction
1
2006
87
0.060
Why?
Cells, Cultured
3
2019
2943
0.060
Why?
Chronic Disease
2
2020
983
0.060
Why?
RNA, Small Interfering
3
2014
567
0.060
Why?
Crohn Disease
2
2025
806
0.060
Why?
Cytokines
4
2017
872
0.060
Why?
Intestinal Absorption
1
2006
126
0.060
Why?
Clathrin-Coated Vesicles
1
2005
10
0.060
Why?
Porins
1
2005
24
0.060
Why?
Adhesins, Bacterial
1
2005
36
0.060
Why?
T-Lymphocytes
2
2018
1316
0.060
Why?
Lectins
1
2005
86
0.060
Why?
Genes, Reporter
1
2005
281
0.050
Why?
Ion Transport
2
2018
87
0.050
Why?
Drug Storage
1
2024
4
0.050
Why?
Ophthalmic Solutions
1
2024
14
0.050
Why?
Male
7
2025
45870
0.050
Why?
Computational Biology
1
2008
584
0.050
Why?
Eye Infections, Bacterial
1
2024
12
0.050
Why?
Triglycerides
2
2015
236
0.050
Why?
Drosophila
1
2008
539
0.050
Why?
Microbial Sensitivity Tests
1
2024
153
0.050
Why?
Colectomy
1
2025
192
0.050
Why?
Drosophila Proteins
1
2008
523
0.050
Why?
Pseudomonas aeruginosa
1
2005
202
0.050
Why?
Middle Aged
5
2025
28363
0.050
Why?
Computer Simulation
1
2008
1158
0.050
Why?
Cell Movement
2
2021
820
0.050
Why?
Single-Cell Analysis
1
2025
204
0.050
Why?
Freeze Fracturing
1
2022
12
0.050
Why?
Tissue Distribution
3
2010
297
0.050
Why?
Reproducibility of Results
2
2022
2883
0.050
Why?
Phenotype
2
2020
2579
0.050
Why?
Receptor Aggregation
1
2002
3
0.050
Why?
beta-Cyclodextrins
1
2002
10
0.050
Why?
Gene Knockdown Techniques
2
2013
257
0.050
Why?
Ligands
2
2019
478
0.050
Why?
Blotting, Western
2
2014
798
0.040
Why?
fas Receptor
1
2002
77
0.040
Why?
Tumor Stem Cell Assay
1
2021
41
0.040
Why?
Drug Discovery
1
2022
118
0.040
Why?
Solute Carrier Family 12, Member 2
2
2012
16
0.040
Why?
Drug Repositioning
1
2021
26
0.040
Why?
Green Fluorescent Proteins
2
2012
313
0.040
Why?
Cyclic N-Oxides
1
2020
33
0.040
Why?
Protein Structure, Tertiary
2
2013
750
0.040
Why?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1
2020
36
0.040
Why?
Bayes Theorem
1
2022
404
0.040
Why?
Young Adult
2
2025
7025
0.040
Why?
Cholecalciferol
1
2020
35
0.040
Why?
Adult
4
2025
28718
0.040
Why?
Vimentin
1
2020
49
0.040
Why?
Spin Labels
1
2020
107
0.040
Why?
Tight Junction Proteins
1
2020
14
0.040
Why?
Bacteria
1
2024
517
0.040
Why?
Tubulin
1
2020
61
0.040
Why?
Adaptor Proteins, Signal Transducing
1
2002
307
0.040
Why?
Alveolar Epithelial Cells
1
2020
18
0.040
Why?
Carrier Proteins
2
2019
684
0.040
Why?
Ribosomes
1
2020
122
0.040
Why?
Liver
2
2015
1238
0.040
Why?
CRISPR-Cas Systems
1
2020
98
0.040
Why?
Trinitrobenzenesulfonic Acid
1
2019
16
0.040
Why?
Connexin 43
1
2020
94
0.040
Why?
Astrocytes
1
2020
151
0.040
Why?
Metagenomics
1
2020
100
0.040
Why?
Mice, Nude
1
2021
842
0.040
Why?
Respiratory Mucosa
1
2020
90
0.040
Why?
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
1
2020
176
0.040
Why?
Gene Expression Profiling
1
2025
1534
0.040
Why?
DNA, Bacterial
1
2020
253
0.040
Why?
Cations, Divalent
1
2019
39
0.040
Why?
RNA, Ribosomal, 16S
1
2020
259
0.040
Why?
Potassium Channels, Voltage-Gated
1
2020
127
0.040
Why?
Gene Expression Regulation, Neoplastic
1
2025
1351
0.040
Why?
Cost-Benefit Analysis
1
2022
501
0.040
Why?
Toll-Like Receptor 4
1
2019
93
0.040
Why?
Gene Deletion
1
2020
358
0.040
Why?
Lipopolysaccharides
1
2020
305
0.040
Why?
Zonula Occludens-2 Protein
1
2018
11
0.040
Why?
High-Throughput Nucleotide Sequencing
1
2022
539
0.040
Why?
Biological Transport, Active
1
2018
105
0.040
Why?
Connexins
1
2020
206
0.040
Why?
Phosphothreonine
1
2018
4
0.040
Why?
Hemorrhage
1
2020
294
0.040
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2018
66
0.040
Why?
Feces
1
2020
360
0.040
Why?
Dynamins
1
2018
50
0.030
Why?
Dexamethasone
1
2019
351
0.030
Why?
Enzyme Activation
2
2010
692
0.030
Why?
HEK293 Cells
1
2020
706
0.030
Why?
Mutation
2
2020
4374
0.030
Why?
Citrobacter rodentium
1
2017
14
0.030
Why?
Iron
1
2018
179
0.030
Why?
Cytoplasm
1
2018
288
0.030
Why?
Protein Structure, Secondary
1
2018
342
0.030
Why?
Pilot Projects
1
2020
938
0.030
Why?
Protein Multimerization
1
2018
196
0.030
Why?
Microfilament Proteins
1
2018
214
0.030
Why?
Gene Regulatory Networks
1
2019
321
0.030
Why?
Caspases
2
2011
156
0.030
Why?
Crystallography, X-Ray
1
2018
527
0.030
Why?
Histological Techniques
1
2016
37
0.030
Why?
Cerebellum
1
2018
253
0.030
Why?
Iodine
1
2016
44
0.030
Why?
Inulin
1
2015
17
0.030
Why?
Sodium
1
2017
340
0.030
Why?
Aged
3
2020
20964
0.030
Why?
Recombinant Proteins
2
2010
1034
0.030
Why?
Water
1
2017
307
0.030
Why?
Organ Size
1
2016
379
0.030
Why?
Patch-Clamp Techniques
1
2015
402
0.030
Why?
Dynactin Complex
1
2014
2
0.030
Why?
Observer Variation
1
2016
626
0.030
Why?
Benzyl Compounds
1
2014
7
0.030
Why?
Nocodazole
1
2014
18
0.030
Why?
Dyneins
1
2014
14
0.030
Why?
Immunoblotting
1
2015
280
0.030
Why?
Madin Darby Canine Kidney Cells
1
2014
23
0.030
Why?
Risk Factors
1
2025
5960
0.030
Why?
Tubulin Modulators
1
2014
23
0.030
Why?
Fluorescent Antibody Technique
1
2015
326
0.030
Why?
Lymphocyte Activation
2
2009
810
0.030
Why?
Cholesterol, VLDL
1
2014
14
0.030
Why?
Brain Neoplasms
1
2020
855
0.030
Why?
Adenine
1
2014
92
0.030
Why?
Models, Molecular
1
2018
1375
0.030
Why?
Jejunum
1
2014
80
0.030
Why?
Golgi Apparatus
1
2014
117
0.030
Why?
B-Lymphocytes
1
2018
771
0.030
Why?
Biomarkers
1
2020
1933
0.030
Why?
Microtubule-Associated Proteins
1
2014
187
0.020
Why?
RNA Interference
1
2014
385
0.020
Why?
Colforsin
1
2012
75
0.020
Why?
Biotinylation
1
2012
42
0.020
Why?
Diterpenes
1
2012
24
0.020
Why?
Adoptive Transfer
1
2013
175
0.020
Why?
Acrylamides
1
2012
35
0.020
Why?
Sequence Deletion
1
2013
213
0.020
Why?
Electric Conductivity
1
2012
147
0.020
Why?
Cholesterol, LDL
1
2014
246
0.020
Why?
Weight Loss
1
2013
240
0.020
Why?
Contrast Media
1
2016
1096
0.020
Why?
Dopamine
1
2012
282
0.020
Why?
Retrospective Studies
1
2025
10286
0.020
Why?
Electrophysiology
1
2011
406
0.020
Why?
Luminescent Proteins
1
2011
145
0.020
Why?
MARVEL Domain Containing 2 Protein
1
2010
2
0.020
Why?
Microscopy, Immunoelectron
1
2010
29
0.020
Why?
Subcellular Fractions
1
2010
95
0.020
Why?
Tissue Culture Techniques
1
2010
82
0.020
Why?
Plasmids
1
2010
291
0.020
Why?
Sequence Homology, Amino Acid
1
2010
422
0.020
Why?
Egtazic Acid
1
2008
33
0.020
Why?
Dose-Response Relationship, Drug
1
2012
1973
0.020
Why?
Protein Kinase C-delta
1
2008
29
0.020
Why?
Carbazoles
1
2008
31
0.020
Why?
Protein Kinase C-alpha
1
2008
29
0.020
Why?
Mucous Membrane
1
2008
85
0.020
Why?
Major Histocompatibility Complex
1
2008
86
0.020
Why?
Microscopy, Electron, Transmission
1
2008
138
0.020
Why?
Microscopy, Confocal
1
2008
286
0.020
Why?
Lymphotoxin beta Receptor
1
2007
28
0.020
Why?
Cardiac Myosins
1
2007
19
0.020
Why?
Adolescent
1
2020
9896
0.020
Why?
Glucose
1
2009
701
0.020
Why?
Amino Acid Sequence
1
2010
2092
0.020
Why?
Base Sequence
1
2010
2344
0.020
Why?
Pyocyanine
1
2005
12
0.010
Why?
Molecular Sequence Data
1
2010
3041
0.010
Why?
CD4-Positive T-Lymphocytes
1
2008
488
0.010
Why?
Computer Systems
1
2005
79
0.010
Why?
Virulence
1
2005
279
0.010
Why?
Kidney
1
2009
1156
0.010
Why?
Phylogeny
1
2010
1275
0.010
Why?
Escherichia coli Infections
1
2004
36
0.010
Why?
RNA, Messenger
1
2010
2092
0.010
Why?
Severity of Illness Index
1
2008
1981
0.010
Why?
Nystatin
1
2002
2
0.010
Why?
Filipin
1
2002
2
0.010
Why?
Fas-Associated Death Domain Protein
1
2002
7
0.010
Why?
Cyclodextrins
1
2002
7
0.010
Why?
Ionophores
1
2002
14
0.010
Why?
Amino Acid Chloromethyl Ketones
1
2002
25
0.010
Why?
Caspase 8
1
2002
35
0.010
Why?
Caspase 9
1
2002
49
0.010
Why?
Aged, 80 and over
1
2013
7232
0.010
Why?
Caspase Inhibitors
1
2002
32
0.010
Why?
Membrane Microdomains
1
2002
54
0.010
Why?
Membrane Potentials
1
2002
442
0.010
Why?
Fluorescent Dyes
1
2002
262
0.010
Why?
Lymphocytes
1
2002
489
0.010
Why?
Mitochondria
1
2002
623
0.010
Why?
Anti-Bacterial Agents
1
2002
847
0.010
Why?
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