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Connection

Eric C. Beyer to Gap Junctions

This is a "connection" page, showing publications Eric C. Beyer has written about Gap Junctions.
Connection Strength

9.290
  1. Gap junction gene and protein families: Connexins, innexins, and pannexins. Biochim Biophys Acta Biomembr. 2018 Jan; 1860(1):5-8.
    View in: PubMed
    Score: 0.559
  2. Are these connexins compatible and does it matter? Channels (Austin). 2015; 9(2):63-4.
    View in: PubMed
    Score: 0.474
  3. Structural organization of intercellular channels II. Amino terminal domain of the connexins: sequence, functional roles, and structure. Biochim Biophys Acta. 2012 Aug; 1818(8):1823-30.
    View in: PubMed
    Score: 0.379
  4. Oxidative stress, lens gap junctions, and cataracts. Antioxid Redox Signal. 2009 Feb; 11(2):339-53.
    View in: PubMed
    Score: 0.314
  5. An intact connexin N-terminus is required for function but not gap junction formation. J Cell Sci. 2008 Aug 15; 121(Pt 16):2744-50.
    View in: PubMed
    Score: 0.303
  6. Cx30.2 can form heteromeric gap junction channels with other cardiac connexins. Biochem Biophys Res Commun. 2008 May 02; 369(2):388-94.
    View in: PubMed
    Score: 0.294
  7. N-terminal residues in Cx43 and Cx40 determine physiological properties of gap junction channels, but do not influence heteromeric assembly with each other or with Cx26. J Cell Sci. 2006 Jun 01; 119(Pt 11):2258-68.
    View in: PubMed
    Score: 0.261
  8. Connexin channels and hemichannels are modulated differently by charge reversal at residues forming the intracellular pocket. Biol Res. 2024 May 23; 57(1):31.
    View in: PubMed
    Score: 0.227
  9. Connexin43 and connexin26 form gap junctions, but not heteromeric channels in co-expressing cells. J Cell Sci. 2004 May 15; 117(Pt 12):2469-80.
    View in: PubMed
    Score: 0.226
  10. Pathways for degradation of connexins and gap junctions. Cardiovasc Res. 2004 May 01; 62(2):256-67.
    View in: PubMed
    Score: 0.226
  11. New developments in the gap junction field: report from the 2002 ASCB meeting. Cell Commun Adhes. 2003 Jan-Feb; 10(1):55-8.
    View in: PubMed
    Score: 0.206
  12. Gap junction synthesis and degradation as therapeutic targets. Curr Drug Targets. 2002 Dec; 3(6):409-16.
    View in: PubMed
    Score: 0.205
  13. Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice. Cells. 2022 09 07; 11(18).
    View in: PubMed
    Score: 0.202
  14. Connexin43 and connexin45 form heteromeric gap junction channels in which individual components determine permeability and regulation. Circ Res. 2002 May 31; 90(10):1100-7.
    View in: PubMed
    Score: 0.198
  15. Gap junction channels formed by coexpressed connexin40 and connexin43. Am J Physiol Heart Circ Physiol. 2001 Oct; 281(4):H1675-89.
    View in: PubMed
    Score: 0.189
  16. Heteromeric connexons formed by the lens connexins, connexin43 and connexin56. Eur J Cell Biol. 2001 Jan; 80(1):11-9.
    View in: PubMed
    Score: 0.179
  17. Heteromeric mixing of connexins: compatibility of partners and functional consequences. Cell Commun Adhes. 2001; 8(4-6):199-204.
    View in: PubMed
    Score: 0.179
  18. Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome. Int J Mol Sci. 2020 Nov 24; 21(23).
    View in: PubMed
    Score: 0.178
  19. Connexin and gap junction degradation. Methods. 2000 Feb; 20(2):180-7.
    View in: PubMed
    Score: 0.168
  20. The Connexin50D47A Mutant Causes Cataracts by Calcium Precipitation. Invest Ophthalmol Vis Sci. 2019 05 01; 60(6):2336-2346.
    View in: PubMed
    Score: 0.160
  21. Cultured chicken embryo lens cells resemble differentiating fiber cells in vivo and contain two kinetic pools of connexin56. Exp Eye Res. 1999 Apr; 68(4):475-84.
    View in: PubMed
    Score: 0.159
  22. Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes. Cardiovasc Res. 1998 Jun; 38(3):711-8.
    View in: PubMed
    Score: 0.150
  23. Degradation of connexin43 gap junctions involves both the proteasome and the lysosome. Exp Cell Res. 1997 Nov 01; 236(2):482-92.
    View in: PubMed
    Score: 0.144
  24. Evidence for heteromeric gap junction channels formed from rat connexin43 and human connexin37. Am J Physiol. 1997 10; 273(4):C1386-96.
    View in: PubMed
    Score: 0.143
  25. Connexin23 deletion does not affect lens transparency. Exp Eye Res. 2016 05; 146:283-288.
    View in: PubMed
    Score: 0.129
  26. The molecular basis of anisotropy: role of gap junctions. J Cardiovasc Electrophysiol. 1995 Jun; 6(6):498-510.
    View in: PubMed
    Score: 0.122
  27. Distinct behavior of connexin56 and connexin46 gap junctional channels can be predicted from the behavior of their hemi-gap-junctional channels. Biophys J. 1995 May; 68(5):1796-803.
    View in: PubMed
    Score: 0.121
  28. Cardiac intercellular communication: consequences of connexin distribution and diversity. Braz J Med Biol Res. 1995 Apr; 28(4):415-25.
    View in: PubMed
    Score: 0.120
  29. The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating. J Membr Biol. 2015 Feb; 248(1):145-55.
    View in: PubMed
    Score: 0.117
  30. Connexin40 abnormalities and atrial fibrillation in the human heart. J Mol Cell Cardiol. 2014 Nov; 76:159-68.
    View in: PubMed
    Score: 0.116
  31. Degradation of a connexin40 mutant linked to atrial fibrillation is accelerated. J Mol Cell Cardiol. 2014 Sep; 74:330-9.
    View in: PubMed
    Score: 0.114
  32. Characterization of the gap junction protein, connexin45. J Membr Biol. 1994 Apr; 139(1):31-40.
    View in: PubMed
    Score: 0.112
  33. Atrial fibrillation-associated connexin40 mutants make hemichannels and synergistically form gap junction channels with novel properties. FEBS Lett. 2014 Apr 17; 588(8):1458-64.
    View in: PubMed
    Score: 0.111
  34. Roles and regulation of lens epithelial cell connexins. FEBS Lett. 2014 Apr 17; 588(8):1297-303.
    View in: PubMed
    Score: 0.111
  35. Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Mol Biol Cell. 2012 Sep; 23(17):3299-311.
    View in: PubMed
    Score: 0.100
  36. Inducible coexpression of connexin37 or connexin40 with connexin43 selectively affects intercellular molecular transfer. J Membr Biol. 2012 Jun; 245(5-6):231-41.
    View in: PubMed
    Score: 0.099
  37. Atomic force microscopy of Connexin40 gap junction hemichannels reveals calcium-dependent three-dimensional molecular topography and open-closed conformations of both the extracellular and cytoplasmic faces. J Biol Chem. 2011 Jun 24; 286(25):22139-46.
    View in: PubMed
    Score: 0.092
  38. The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation. Mol Vis. 2009 Sep 14; 15:1881-5.
    View in: PubMed
    Score: 0.082
  39. A mutant connexin50 with enhanced hemichannel function leads to cell death. Invest Ophthalmol Vis Sci. 2009 Dec; 50(12):5837-45.
    View in: PubMed
    Score: 0.082
  40. Connexin40 and connexin43 determine gating properties of atrial gap junction channels. J Mol Cell Cardiol. 2010 Jan; 48(1):238-45.
    View in: PubMed
    Score: 0.080
  41. The N terminus of connexin37 contains an alpha-helix that is required for channel function. J Biol Chem. 2009 Jul 24; 284(30):20418-27.
    View in: PubMed
    Score: 0.080
  42. Cataracts are caused by alterations of a critical N-terminal positive charge in connexin50. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2549-56.
    View in: PubMed
    Score: 0.074
  43. A novel GJA8 mutation is associated with autosomal dominant lamellar pulverulent cataract: further evidence for gap junction dysfunction in human cataract. J Med Genet. 2006 Jan; 43(1):e2.
    View in: PubMed
    Score: 0.063
  44. Dynamic model for ventricular junctional conductance during the cardiac action potential. Am J Physiol Heart Circ Physiol. 2005 Mar; 288(3):H1113-23.
    View in: PubMed
    Score: 0.058
  45. Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis. Biochem Biophys Res Commun. 2004 Jul 09; 319(4):1144-51.
    View in: PubMed
    Score: 0.057
  46. Amino terminal glutamate residues confer spermine sensitivity and affect voltage gating and channel conductance of rat connexin40 gap junctions. J Physiol. 2004 Jun 15; 557(Pt 3):863-78.
    View in: PubMed
    Score: 0.056
  47. Plasma membrane channels formed by connexins: their regulation and functions. Physiol Rev. 2003 Oct; 83(4):1359-400.
    View in: PubMed
    Score: 0.054
  48. A carboxyl terminal domain of connexin43 is critical for gap junction plaque formation but not for homo- or hetero-oligomerization. Cell Commun Adhes. 2003 Jul-Dec; 10(4-6):323-8.
    View in: PubMed
    Score: 0.053
  49. Functional role of the carboxyl terminal domain of human connexin 50 in gap junctional channels. J Membr Biol. 2002 Mar 15; 186(2):101-12.
    View in: PubMed
    Score: 0.049
  50. Redistribution of connexin45 in gap junctions of connexin43-deficient hearts. Cardiovasc Res. 2002 Mar; 53(4):921-35.
    View in: PubMed
    Score: 0.049
  51. Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation. J Biol Chem. 2022 03; 298(3):101673.
    View in: PubMed
    Score: 0.048
  52. Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant. Biophys J. 2021 12 21; 120(24):5644-5656.
    View in: PubMed
    Score: 0.048
  53. Connexin46 mutations linked to congenital cataract show loss of gap junction channel function. Am J Physiol Cell Physiol. 2000 Sep; 279(3):C596-602.
    View in: PubMed
    Score: 0.044
  54. Functional expression and biophysical properties of polymorphic variants of the human gap junction protein connexin37. Biochem Biophys Res Commun. 2000 Jul 21; 274(1):216-24.
    View in: PubMed
    Score: 0.043
  55. Gap junctions in the chicken pineal gland. Brain Res. 2000 Apr 10; 861(2):257-70.
    View in: PubMed
    Score: 0.043
  56. Heterogeneous localization of connexin40 in the renal vasculature. Microvasc Res. 2000 Jan; 59(1):140-8.
    View in: PubMed
    Score: 0.042
  57. Co-expression of lens fiber connexins modifies hemi-gap-junctional channel behavior. Biophys J. 1999 Jan; 76(1 Pt 1):198-206.
    View in: PubMed
    Score: 0.039
  58. Cloning and functional expression of a novel gap junction channel from the retina of Danio aquipinnatus. Vis Neurosci. 1998 Nov-Dec; 15(6):1137-44.
    View in: PubMed
    Score: 0.039
  59. Differential expression of gap junction proteins in the canine sinus node. Circ Res. 1998 Mar 23; 82(5):604-12.
    View in: PubMed
    Score: 0.037
  60. Disparate effects of deficient expression of connexin43 on atrial and ventricular conduction: evidence for chamber-specific molecular determinants of conduction. Circulation. 1998 Feb 24; 97(7):686-91.
    View in: PubMed
    Score: 0.037
  61. Disruption of the lens circulation causes calcium accumulation and precipitates in connexin mutant mice. Am J Physiol Cell Physiol. 2018 04 01; 314(4):C492-C503.
    View in: PubMed
    Score: 0.036
  62. Physiological and Optical Alterations Precede the Appearance of Cataracts in Cx46fs380 Mice. Invest Ophthalmol Vis Sci. 2017 08 01; 58(10):4366–4374.
    View in: PubMed
    Score: 0.035
  63. The gap-junction protein connexin 56 is phosphorylated in the intracellular loop and the carboxy-terminal region. Eur J Biochem. 1997 Feb 15; 244(1):89-97.
    View in: PubMed
    Score: 0.034
  64. Selectivity of connexin-specific gap junctions does not correlate with channel conductance. Circ Res. 1995 Dec; 77(6):1156-65.
    View in: PubMed
    Score: 0.032
  65. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):11071-5.
    View in: PubMed
    Score: 0.031
  66. Unique conductance, gating, and selective permeability properties of gap junction channels formed by connexin40. Circ Res. 1995 Oct; 77(4):813-22.
    View in: PubMed
    Score: 0.031
  67. Gap junction protein phenotypes of the human heart and conduction system. J Cardiovasc Electrophysiol. 1995 Oct; 6(10 Pt 1):813-22.
    View in: PubMed
    Score: 0.031
  68. Transfected connexin45 alters gap junction permeability in cells expressing endogenous connexin43. J Cell Biol. 1995 Aug; 130(4):987-95.
    View in: PubMed
    Score: 0.031
  69. Structural and molecular determinants of intercellular coupling in cardiac myocytes. Microsc Res Tech. 1995 Aug 01; 31(5):357-63.
    View in: PubMed
    Score: 0.031
  70. Properties of gap junction channels formed of connexin 45 endogenously expressed in human hepatoma (SKHep1) cells. Am J Physiol. 1995 Feb; 268(2 Pt 1):C356-65.
    View in: PubMed
    Score: 0.030
  71. Connexin 43 and connexin 40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivo. Am J Physiol. 1995 Feb; 268(2 Pt 2):H729-39.
    View in: PubMed
    Score: 0.030
  72. Localization and distribution of gap junctions in normal and cardiomyopathic hamster heart. J Morphol. 1994 Nov; 222(2):203-13.
    View in: PubMed
    Score: 0.029
  73. Characterization of the gap junction protein connexin56 in the chicken lens by immunofluorescence and immunoblotting. Invest Ophthalmol Vis Sci. 1994 Nov; 35(12):4109-17.
    View in: PubMed
    Score: 0.029
  74. Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties. J Am Coll Cardiol. 1994 Oct; 24(4):1124-32.
    View in: PubMed
    Score: 0.029
  75. Selective dye and ionic permeability of gap junction channels formed by connexin45. Circ Res. 1994 Sep; 75(3):483-90.
    View in: PubMed
    Score: 0.029
  76. Bovine connexin44, a lens gap junction protein: molecular cloning, immunologic characterization, and functional expression. Invest Ophthalmol Vis Sci. 1994 Sep; 35(10):3747-58.
    View in: PubMed
    Score: 0.029
  77. Electrical properties of mammalian lens epithelial gap junction channels. Invest Ophthalmol Vis Sci. 1994 Aug; 35(9):3422-8.
    View in: PubMed
    Score: 0.029
  78. Gap junction protein connexin43 exacerbates lung vascular permeability. PLoS One. 2014; 9(6):e100931.
    View in: PubMed
    Score: 0.029
  79. Connexin37 forms high conductance gap junction channels with subconductance state activity and selective dye and ionic permeabilities. Biophys J. 1994 Jun; 66(6):1915-28.
    View in: PubMed
    Score: 0.028
  80. Differential expression of two gap junction proteins in corneal epithelium. Eur J Cell Biol. 1994 Jun; 64(1):95-100.
    View in: PubMed
    Score: 0.028
  81. Tissue-specific determinants of anisotropic conduction velocity in canine atrial and ventricular myocardium. Circ Res. 1994 Jun; 74(6):1065-70.
    View in: PubMed
    Score: 0.028
  82. c-Src kinase inhibition reduces arrhythmia inducibility and connexin43 dysregulation after myocardial infarction. J Am Coll Cardiol. 2014 Mar 11; 63(9):928-34.
    View in: PubMed
    Score: 0.028
  83. A connexin50 mutant, CX50fs, that causes cataracts is unstable, but is rescued by a proteasomal inhibitor. J Biol Chem. 2013 Jul 12; 288(28):20427-34.
    View in: PubMed
    Score: 0.026
  84. Cytoplasmic amino acids within the membrane interface region influence connexin oligomerization. J Membr Biol. 2012 Jun; 245(5-6):221-30.
    View in: PubMed
    Score: 0.025
  85. Different consequences of cataract-associated mutations at adjacent positions in the first extracellular boundary of connexin50. Am J Physiol Cell Physiol. 2011 May; 300(5):C1055-64.
    View in: PubMed
    Score: 0.022
  86. An aberrant sequence in a connexin46 mutant underlies congenital cataracts. J Biol Chem. 2005 Dec 09; 280(49):40788-95.
    View in: PubMed
    Score: 0.016
  87. Cardiac gap junction channels show quantitative differences in selectivity. Circ Res. 2002 Jul 26; 91(2):104-11.
    View in: PubMed
    Score: 0.013
  88. Heterotypic docking of Cx43 and Cx45 connexons blocks fast voltage gating of Cx43. Biophys J. 2001 Sep; 81(3):1406-18.
    View in: PubMed
    Score: 0.012
  89. Dephosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia. Circ Res. 2000 Oct 13; 87(8):656-62.
    View in: PubMed
    Score: 0.011
  90. Peptide inhibitors of intercellular communication. Am J Physiol Lung Cell Mol Physiol. 2000 Oct; 279(4):L619-22.
    View in: PubMed
    Score: 0.011
  91. Molecular mechanism underlying a Cx50-linked congenital cataract. Am J Physiol. 1999 06; 276(6):C1443-6.
    View in: PubMed
    Score: 0.010
  92. Effects of angiotensin II on expression of the gap junction channel protein connexin43 in neonatal rat ventricular myocytes. J Am Coll Cardiol. 1998 Sep; 32(3):800-7.
    View in: PubMed
    Score: 0.010
  93. Mechanisms for the coordination of intercellular calcium signaling in insulin-secreting cells. J Cell Sci. 1997 Feb; 110 ( Pt 4):497-504.
    View in: PubMed
    Score: 0.009
  94. Expression of zebrafish connexin43.4 in the notochord and tail bud of wild-type and mutant no tail embryos. Dev Biol. 1996 Aug 01; 177(2):449-62.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.