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Harriet De Wit

TitleProfessor
InstitutionUniversity of Chicago
DepartmentPsychiatry and Behavioral Neuroscience-Research
AddressChicago IL 60637
Email
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    Collapse Overview 
    Collapse overview
    The de Wit laboratory investigates the subjective, behavioral and physiological effects of drugs of abuse in healthy human volunteers. Some studies are designed to identify individual differences and risk factors for excessive use, and others to determine the effects of drugs on mood, psychomotor and cognitive performance, and brain activity. Another major interest is the study of conditioned drug effects, or cues, that influence future drug use.
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    Collapse Biography 
    Collapse education and training
    University of Calgary, Calgary CanadaBA1969Psychology
    Concordia University, Montreal CanadaPhD02/1981Experimental Psychology
    Collapse awards and honors
    1999Solvay Award for Outstanding Basic Psychopharmacological Research in Affective Disorders , American Psychological Association
    2009Marian W. Fischman Memorial Lectureship Award, College of Problems on Drug Dependence
    2016Distinguished Lecturer, Elizabeth Fitzgerald Sporar Endowment Distinguished Initiatives in Addiction, University of Texas
    2019Distinguished Achievement Award, European Behavioural Pharmacology Society
    2020Lifetime Achievement Award, Research Society on Alcoholism
    2020John F. Lemieux Medal for Distinguished Alumni, Concordia University, Montreal

    Collapse Research 
    Collapse research activities and funding
    R13DA061597     (DE WIT, HARRIET)Sep 1, 2024 - Aug 31, 2025
    NIH
    European Behavioral Pharmacology Society (EPBS) workshop on Novel Pharmacotherapies to Treat Substance Use Disorders: From Basic Science to Societal Implications
    Role: Principal Investigator
    T32DA043469     (HEDEKER, DONALD)Jul 1, 2017 - Jun 30, 2027
    NIH
    Integrative Training in the Neurobiology of Addictive Behaviors
    Role: Principal Investigator
    R21DA037642     (DE WIT, HARRIET)Apr 1, 2015 - Mar 31, 2018
    NIH
    Inhibitory Control and Drug Reward in Humans
    Role: Principal Investigator
    R21DA031796     (DE WIT, HARRIET)Feb 15, 2012 - Jan 31, 2016
    NIH
    Memory effects of stimulant drugs in humans
    Role: Principal Investigator
    R01DA032015     (DE WIT, HARRIET)Jul 15, 2011 - Apr 30, 2018
    NIH
    The genetic basis of impulsive behavior in humans
    Role: Principal Investigator
    R21DA026570     (DE WIT, HARRIET)Sep 30, 2009 - Aug 31, 2013
    NIH
    Is Ecstasy an Empathogen? Effects of MDMA on Social and Emotional Processing
    Role: Principal Investigator
    R21DA020773     (DE WIT, HARRIET)Jun 1, 2007 - Feb 28, 2009
    NIH
    Craving During Smoking Abstinence: Does it Abate or Incubate?
    Role: Principal Investigator
    R03AA013729     (DE WIT, HARRIET)Sep 15, 2002 - Aug 31, 2005
    NIH
    Nicotinic Involvement &Consumption of Alcohol in Humans
    Role: Principal Investigator
    R03DA012143     (DE WIT, HARRIET)Sep 30, 1999 - Sep 29, 2001
    NIH
    BLOCKADE OF METHAMPHETAMINE SUBJECTIVE EFFECTS IN HUMANS
    Role: Principal Investigator
    R01DA009133     (DE WIT, HARRIET)Apr 20, 1996 - Mar 31, 2012
    NIH
    Drug Abuse and Impulsivity: Human Laboratory Models
    Role: Principal Investigator
    R01DA006176     (DE WIT, HARRIET)Mar 1, 1990 - Feb 29, 1996
    NIH
    DRUGS OF ABUSE ON REGIONAL CEREBRAL METABOLISM AND MOOD
    Role: Principal Investigator
    R01DA005704     (ZACNY, JAMES P.)Sep 1, 1989 - Jun 30, 1996
    NIH
    BEHAVIORAL ECONOMICS OF DRUG CHOICE
    Role: Co-Principal Investigator
    R01DA003517     (DE WIT, HARRIET)May 1, 1984 - Jul 31, 2001
    NIH
    PHARMACOLOGIC STUDIES OF MARIJUANA &ALPHA THC IN HUMAN
    Role: Principal Investigator
    R01DA002812     (DE WIT, HARRIET)Jan 1, 1981 - Jan 31, 2025
    NIH
    Determinants of Drug Preference in Humans
    Role Description: The goal of the study is to identify individual differences in brain reward processes related to stimulant-induced euphoria.
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Martinez RL, Radošic N, Molla H, de Wit H, Lyubomirsky S. The empathogen 3,4-methylenedioxymethamphetamine, but not methamphetamine, increases feelings of global trust. J Psychopharmacol. 2025 Sep 16; 2698811251370999. PMID: 40958371.
      Citations:    Fields:    
    2. London ED, Groman SM, Leyton M, de Wit H. The mesocorticolimbic system in stimulant use disorder. Mol Psychiatry. 2025 Nov; 30(11):5486-5499. PMID: 40926091; PMCID: PMC12532603.
      Citations:    Fields:    Translation:HumansAnimals
    3. Rodriguez Santos LG, Molla H, Babaeianjelodar M, de Wit H, Yip SW. Connectome-based encoding of subjective drug responses to acute oral methamphetamine. Neuropsychopharmacology. 2025 Nov; 50(12):1787-1794. PMID: 40866561; PMCID: PMC12518554.
      Citations:    Fields:    Translation:Humans
    4. Gonzalez J, Tran V, Meredith J, Xu I, Penchala R, Vilar Ribo L, Courchesne-Krak NS, Zoleikhaeian D, 23andMe Research Team, McIntyre M, Fontanillas P, Kukar Bond K, Johnson EO, Jeffery A, MacKillop J, Marienfeld C, de Wit H, Palmer AA, Sanchez-Roige S. How it begins: Initial response to opioids strongly predicts self-reported opioid use disorder. medRxiv. 2025 Aug 05. PMID: 40166554; PMCID: PMC11957173.
      Citations:    
    5. Kirschner H, Molla HM, Nassar MR, de Wit H, Ullsperger M. Methamphetamine-induced adaptation of learning rate dynamics depend on baseline performance. Elife. 2025 Jul 21; 13. PMID: 40689876; PMCID: PMC12279372.
      Citations:    Fields:    Translation:Humans
    6. Hahn EC, Molla H, Cooper JA, DeBrosse J, de Wit H. Effects of methamphetamine on human effort task performance are unrelated to its subjective effects. Psychopharmacology (Berl). 2026 Jan; 243(1):199-209. PMID: 40627130; PMCID: PMC12881056.
      Citations:    Fields:    Translation:Humans
    7. Lyu Y, Corriveau A, Molla H, de Wit H, Rosenberg MD. Methamphetamine modulates functional connectivity signatures of sustained attention and arousal. bioRxiv. 2025 May 21. PMID: 40475570; PMCID: PMC12139791.
      Citations:    
    8. Courchesne-Krak NS, Chandrasekaran AR, Gonzalez J, Bianchi SB, Tran V, Johnson EO, Troiani V, Hettema JM, Stein MB, Coon H, Docherty AR, Berretini WH, MacKillop J, de Wit H, Marienfeld C, Palmer AA, Sanchez-Roige S. Prescription Opioid Medication Survey: A Tool to Collect Deep Phenotypic Data on the Multifactorial Pathways to Opioid Use Disorder in Clinical and Population-Based Cohorts. Complex Psychiatry. 2025 Jan-Dec; 11(1):72-93. PMID: 40621581; PMCID: PMC12226013.
      Citations:    
    9. Molla H, DeBrosse J, Keedy S, Lee R, de Wit H. Effects of methamphetamine on two measures of reward: Euphoria and neural activation to reward cues. Neuropsychopharmacology. 2025 Jul; 50(8):1298-1304. PMID: 40269142; PMCID: PMC12170867.
      Citations: 1     Fields:    Translation:Humans
    10. Kirschner H, Molla HM, Nassar MR, de Wit H, Ullsperger M. Methamphetamine-induced adaptation of learning rate dynamics depend on baseline performance. bioRxiv. 2025 Mar 20. PMID: 39026741; PMCID: PMC11257491.
      Citations:    
    11. de Wit H, Hahn E, Smadi S, Li T, Molla H. MDMA as well as amphetamine and alcohol increase feelings of social closeness in healthy adults. Sci Rep. 2024 12 28; 14(1):31312. PMID: 39732947; PMCID: PMC11682418.
      Citations:    Fields:    Translation:Humans
    12. Bernanke A, Hasley R, Sabetfakhri N, de Wit H, Smith BM, Wang L, Brenner LA, Hanlon C, Philip NS, Ajilore O, Herrold A, Aaronson A. Frontal Pole Neuromodulation for Impulsivity and Suicidality in Veterans With Mild Traumatic Brain Injury and Common Co-Occurring Mental Health Conditions: Protocol for a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2024 Dec 13; 13:e58206. PMID: 39671573; PMCID: PMC11681286.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    13. Haggarty C, Molla H, Glazer J, Tare I, Rains A, de Wit H, Lee R. Low-Dose LSD Alters Early and Late Event-Related Potentials to Emotional Faces. Psychedelic Med (New Rochelle). 2024 Dec; 2(4):210-220. PMID: 40051483; PMCID: PMC11658383.
      Citations:    
    14. Molla H, Novembre G, Bershad A, Handlin L, Perini I, de Wit H, Morrison I. MDMA modulates human sensorimotor cortical pathways during gentle touch. Imaging Neurosci (Camb). 2024; 2. PMID: 40800376; PMCID: PMC12290858.
      Citations:    
    15. Bershad AK, de Wit H. Social Homeostasis and Psychoactive Drugs: What Can We Learn From Opioid and Amphetamine Drug Challenge Studies in Humans? Biol Psychiatry. 2025 May 15; 97(10):982-988. PMID: 39277124.
      Citations:    Fields:    Translation:Humans
    16. Carlyle M, de Wit H, Leknes S. Impact of childhood adversity on acute subjective effects of stimulant and opioid drugs: Evidence from placebo-controlled studies in healthy volunteers. J Psychopharmacol. 2024 Nov; 38(11):986-997. PMID: 39118370; PMCID: PMC11528953.
      Citations: 1     Fields:    Translation:Humans
    17. de Wit H, Holze F, Preller KH. Psychedelics in Medicine: Can Evidence Keep Up With Enthusiasm? Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 May; 9(5):460-461. PMID: 38719373.
      Citations:    Fields:    Translation:Humans
    18. Haggarty CJ, Bershad AK, Kumar MK, Lee R, de Wit H. The 3,4-methylenedioxymethamphetamine enhances early visual processing for salient socio-emotional stimuli. Eur J Neurosci. 2024 Jun; 59(12):3224-3235. PMID: 38637983; PMCID: PMC11406194.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    19. Murray CH, Frohlich J, Haggarty CJ, Tare I, Lee R, de Wit H. Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine. Neuropsychopharmacology. 2024 Jun; 49(7):1120-1128. PMID: 38287172; PMCID: PMC11109226.
      Citations: 7     Fields:    Translation:Humans
    20. Bershad AK, Hsu DT, de Wit H. MDMA enhances positive affective responses to social feedback. J Psychopharmacol. 2024 03; 38(3):297-304. PMID: 38279662; PMCID: PMC11406195.
      Citations: 3     Fields:    Translation:Humans
    21. Murphy RJ, Muthukumaraswamy S, de Wit H. Microdosing Psychedelics: Current Evidence From Controlled Studies. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 May; 9(5):500-511. PMID: 38280630.
      Citations: 6     Fields:    Translation:Humans
    22. Aaronson AL, Smith B, Krese K, Barnhart M, Adamson M, de Wit H, Philip NS, Brenner LA, Bender-Pape T, Herrold AA. Impulsivity and Psychiatric Diagnoses as Mediators of Suicidal Ideation and Suicide Attempts Among Veterans With Traumatic Brain Injury. J Neuropsychiatry Clin Neurosci. 2024; 36(2):125-133. PMID: 38192217; PMCID: PMC11018458.
      Citations: 3     Fields:    Translation:Humans
    23. Haggarty CJ, Glazer JE, Nusslock R, Lee R, de Wit H. Lack of effect of methamphetamine on reward-related brain activity in healthy adults. Psychopharmacology (Berl). 2024 Jan; 241(1):181-193. PMID: 38141075.
      Citations: 2     Fields:    Translation:Humans
    24. Doss MK, Samaha J, Barrett FS, Griffiths RR, de Wit H, Gallo DA, Koen JD. Unique effects of sedatives, dissociatives, psychedelics, stimulants, and cannabinoids on episodic memory: A review and reanalysis of acute drug effects on recollection, familiarity, and metamemory. Psychol Rev. 2024 Mar; 131(2):523-562. PMID: 38095937.
      Citations: 11     Fields:    Translation:Humans
    25. Molla H, Lee R, Tare I, de Wit H. Greater subjective effects of a low dose of LSD in participants with depressed mood. Neuropsychopharmacology. 2024 Apr; 49(5):774-781. PMID: 38042914; PMCID: PMC10948752.
      Citations: 9     Fields:    Translation:Humans
    26. Molla H, Lee R, Lyubomirsky S, de Wit H. Drug-induced social connection: both MDMA and methamphetamine increase feelings of connectedness during controlled dyadic conversations. Sci Rep. 2023 09 22; 13(1):15846. PMID: 37740024; PMCID: PMC10516994.
      Citations: 13     Fields:    Translation:Humans
    27. Bershad AK, de Wit H. Social Psychopharmacology: Novel Approaches to Treat Deficits in Social Motivation in Schizophrenia. Schizophr Bull. 2023 09 07; 49(5):1161-1173. PMID: 37358825; PMCID: PMC10483474.
      Citations: 4     Fields:    Translation:Humans
    28. Han J, Keedy S, de Wit H. Stimulant-like subjective effects of alcohol are not related to resting-state connectivity in healthy men. Cereb Cortex. 2023 08 08; 33(16):9478-9488. PMID: 37339883; PMCID: PMC10656944.
      Citations: 2     Fields:    Translation:Humans
    29. Crane NA, Molla H, de Wit H. Methamphetamine alters nucleus accumbens neural activation to monetary loss in healthy young adults. Psychopharmacology (Berl). 2023 Sep; 240(9):1891-1900. PMID: 37530883; PMCID: PMC10572040.
      Citations: 4     Fields:    Translation:Humans
    30. Molla H, Keedy S, DeBrosse J, de Wit H. Methamphetamine enhances neural activation during anticipation of loss in the monetary incentive delay task. Cereb Cortex Commun. 2023; 4(3):tgad014. PMID: 37565072; PMCID: PMC10412021.
      Citations: 3     
    31. Doss MK, de Wit H, Gallo DA. The acute effects of psychoactive drugs on emotional episodic memory encoding, consolidation, and retrieval: A comprehensive review. Neurosci Biobehav Rev. 2023 07; 150:105188. PMID: 37085021; PMCID: PMC10247427.
      Citations: 10     Fields:    Translation:Humans
    32. Pabon E, de Wit H. Impaired inhibition after delta-9-tetrahydrocannabinol in women not related to circulating estradiol levels. Pharmacol Biochem Behav. 2023 04; 225:173547. PMID: 37004978; PMCID: PMC10957069.
      Citations: 1     Fields:    Translation:HumansAnimalsCTClinical Trials
    33. de Wit H. Progress and Puzzles in Psychedelic Therapy. Biol Psychiatry. 2023 02 01; 93(3):210. PMID: 36567083.
      Citations: 1     Fields:    
    34. Krishnan S, Bevins RA, de Wit H. Place conditioning in humans: opportunities for translational research. Psychopharmacology (Berl). 2023 Nov; 240(11):2221-2230. PMID: 36656336; PMCID: PMC10949408.
      Citations: 2     Fields:    Translation:HumansAnimals
    35. Glazer J, Murray CH, Nusslock R, Lee R, de Wit H. Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity. Neuropsychopharmacology. 2023 01; 48(2):418-426. PMID: 36284231; PMCID: PMC9751270.
      Citations: 21     Fields:    Translation:Humans
    36. Nunez C, Hoots JK, Schepers ST, Bower M, de Wit H, Wardle MC. Pharmacological investigations of effort-based decision-making in humans: Naltrexone and nicotine. PLoS One. 2022; 17(10):e0275027. PMID: 36197897; PMCID: PMC9534411.
      Citations: 3     Fields:    Translation:Humans
    37. Pabon E, Greenlund IM, Carter JR, de Wit H. Effects of alcohol on sleep and nocturnal heart rate: Relationships to intoxication and morning-after effects. Alcohol Clin Exp Res. 2022 10; 46(10):1875-1887. PMID: 35953878; PMCID: PMC9826048.
      Citations: 6     Fields:    Translation:Humans
    38. de Wit H, D'Souza DC. Psychedelics: Old trips, new destinations in psychopharmacology research. Psychopharmacology (Berl). 2022 Jun; 239(6):1643-1645. PMID: 35460341.
      Citations:    
    39. de Wit H, D'Souza DC. Correction to: Psychedelics: Old trips, new destinations in psychopharmacology research. Psychopharmacology (Berl). 2022 Jun; 239(6):1647. PMID: 35543715.
      Citations:    Fields:    
    40. Murray CH, Glazer JE, Lee R, Nusslock R, de Wit H. ?9-THC reduces reward-related brain activity in healthy adults. Psychopharmacology (Berl). 2022 Sep; 239(9):2829-2840. PMID: 35612654; PMCID: PMC10560585.
      Citations: 4     Fields:    Translation:Humans
    41. Pabon E, de Wit H. Effects of Oral Delta-9-Tetrahydrocannabinol in Women During the Follicular Phase of the Menstrual Cycle. Cannabis Cannabinoid Res. 2023 12; 8(6):1117-1125. PMID: 35593915; PMCID: PMC10714110.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    42. King A, Vena A, de Wit H, Grant JE, Cao D. Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily: A Randomized Clinical Trial. JAMA Netw Open. 2022 Mar 01; 5(3):e220951. PMID: 35244704; PMCID: PMC8897753.
      Citations: 11     Fields:    Translation:Humans
    43. Murray CH, Huang Z, Lee R, de Wit H. Adolescents are more sensitive than adults to acute behavioral and cognitive effects of THC. Neuropsychopharmacology. 2022 06; 47(7):1331-1338. PMID: 35110688; PMCID: PMC9117219.
      Citations: 18     Fields:    Translation:HumansAnimals
    44. Wardle MC, Pabon E, Webber HE, de Wit H. Delta-9-tetrahydrocannabinol reduces willingness to exert effort in women. Psychopharmacology (Berl). 2022 May; 239(5):1487-1497. PMID: 35102424; PMCID: PMC8803458.
      Citations: 4     Fields:    Translation:HumansAnimals
    45. de Wit H, Molla HM, Bershad A, Bremmer M, Lee R. Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study. Addict Biol. 2022 03; 27(2):e13143. PMID: 35106880; PMCID: PMC9731343.
      Citations: 28     Fields:    Translation:Humans
    46. Malina M, Keedy S, Weafer J, Van Hedger K, de Wit H. Effects of Methamphetamine on Within- and Between-Network Connectivity in Healthy Adults. Cereb Cortex Commun. 2021; 2(4):tgab063. PMID: 34859242; PMCID: PMC8633740.
      Citations: 2     
    47. Regan A, Margolis S, de Wit H, Lyubomirsky S. Does ±3,4-methylenedioxymethamphetamine (ecstasy) induce subjective feelings of social connection in humans? A multilevel meta-analysis. PLoS One. 2021; 16(10):e0258849. PMID: 34695117; PMCID: PMC8544845.
      Citations: 9     Fields:    Translation:Humans
    48. Pabon E, Rockwood F, Norman GJ, de Wit H. Acute effects of oral delta-9-tetrahydrocannabinol (THC) on autonomic cardiac activity and their relation to subjective and anxiogenic effects. Psychophysiology. 2022 02; 59(2):e13955. PMID: 34665890; PMCID: PMC8724445.
      Citations: 12     Fields:    Translation:Humans
    49. Murray CH, Tare I, Perry CM, Malina M, Lee R, de Wit H. Low doses of LSD reduce broadband oscillatory power and modulate event-related potentials in healthy adults. Psychopharmacology (Berl). 2022 Jun; 239(6):1735-1747. PMID: 34613430; PMCID: PMC9847217.
      Citations: 27     Fields:    Translation:Humans
    50. Di Ciano P, de Wit H, Mansouri E, Houle S, Boileau I, Le Foll B. The influence of conditioned stimuli on [11C]-(+)-PHNO PET binding in tobacco smokers after a one week abstinence. Sci Rep. 2021 06 03; 11(1):11667. PMID: 34083612; PMCID: PMC8175373.
      Citations: 1     Fields:    Translation:Humans
    51. Nutt DJ, de Wit H. Putting the MD back into MDMA. Nat Med. 2021 06; 27(6):950-951. PMID: 34031606.
      Citations:    Fields:    Translation:Humans
    52. de Wit H, Bershad AK, Grob C. Challenges in translational research: MDMA in the laboratory versus therapeutic settings. J Psychopharmacol. 2022 Mar; 36(3):252-257. PMID: 33944625.
      Citations: 7     Fields:    Translation:Humans
    53. Weafer J, Gorka SM, Dzemidzic M, Kareken DA, Phan KL, de Wit H. Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol. Neuropsychopharmacology. 2021 07; 46(8):1442-1450. PMID: 33947965; PMCID: PMC8208996.
      Citations: 6     Fields:    Translation:Humans
    54. de Wit H, Bershad AK, Hutchison W, Bremmer M. Can MDMA Change Sociopolitical Values? Insights From a Research Participant. Biol Psychiatry. 2021 06 01; 89(11):e61-e62. PMID: 33814127.
      Citations: 3     Fields:    
    55. Van Hedger K, Bershad AK, Madray R, de Wit H, Mayo LM. Effects of Acute Drug Administration on Emotion: A Review of Pharmacological MRI Studies. Curr Addict Rep. 2021 Jun; 8(2):181-193. PMID: 34631363; PMCID: PMC8494189.
      Citations: 2     
    56. Murray CH, Li J, Weafer J, de Wit H. Subjective responses predict d-amphetamine choice in healthy volunteers. Pharmacol Biochem Behav. 2021 05; 204:173158. PMID: 33675838; PMCID: PMC8018542.
      Citations: 4     Fields:    Translation:Humans
    57. Han J, Keedy S, Murray CH, Foxley S, de Wit H. Acute effects of alcohol on resting-state functional connectivity in healthy young men. Addict Behav. 2021 04; 115:106786. PMID: 33421747; PMCID: PMC8693384.
      Citations: 17     Fields:    Translation:Humans
    58. Pabon E, Crane NA, Radoman M, Weafer J, Langenecker SA, Phan KL, de Wit H. Neural activation during anticipation of monetary gain or loss does not associate with positive subjective response to alcohol in binge drinkers. Drug Alcohol Depend. 2021 01 01; 218:108432. PMID: 33250380; PMCID: PMC7750248.
      Citations: 1     Fields:    Translation:Humans
    59. Li J, Murray CH, Weafer J, de Wit H. Subjective Effects of Alcohol Predict Alcohol Choice in Social Drinkers. Alcohol Clin Exp Res. 2020 12; 44(12):2579-2587. PMID: 33201577; PMCID: PMC8076998.
      Citations: 4     Fields:    Translation:Humans
    60. Webber HE, Lopez-Gamundi P, Stamatovich SN, de Wit H, Wardle MC. Using pharmacological manipulations to study the role of dopamine in human reward functioning: A review of studies in healthy adults. Neurosci Biobehav Rev. 2021 01; 120:123-158. PMID: 33202256; PMCID: PMC7855845.
      Citations: 22     Fields:    Translation:HumansAnimals
    61. Radoman M, Crane NA, Gorka SM, Weafer J, Langenecker SA, de Wit H, Phan KL. Striatal activation to monetary reward is associated with alcohol reward sensitivity. Neuropsychopharmacology. 2021 01; 46(2):343-350. PMID: 32505126; PMCID: PMC7852684.
      Citations: 16     Fields:    Translation:Humans
    62. Adam KCS, Doss MK, Pabon E, Vogel EK, de Wit H. ?9-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial. Neuropsychopharmacology. 2020 10; 45(11):1807-1816. PMID: 32386395; PMCID: PMC7608353.
      Citations: 21     Fields:    Translation:Humans
    63. Murray CH, Weafer J, de Wit H. Stability of acute responses to drugs in humans across repeated testing: Findings with alcohol and amphetamine. Drug Alcohol Depend. 2020 07 01; 212:107989. PMID: 32386922; PMCID: PMC7354676.
      Citations: 4     Fields:    Translation:Humans
    64. Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Gordon S, Medland SE, Watson HJ, Bryois J, Hinney A, Mattheisen M, Ripke S, Yao S, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Estivill X, Farmer A, Favaro A, Fichter MM, Fischer K, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Kalsi G, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Lichtenstein P, Norring C, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Murray AD, Nurnberger JI, Preuss U, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson PKE, Nelson EC, Palmer AA, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose RJ, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Wade TD, Heath AC, Montgomery GW, Martin NG, Sullivan PF, Kaprio J, Breen G, Gelernter J, Edenberg HJ, Bulik CM, Agrawal A, Hübel C, Gaspar HA, Leppä VM, Giusti-Rodríguez P, Boehm I, Egberts K, Ehrlich S, Escaramís G, Esko T, Fernández-Aranda F, Föcker M, Guillaume S, Jiménez-Murcia S, Julià A, Kaminská D, Rabionet R, et al. Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addict Biol. 2021 01; 26(1):e12880. PMID: 32064741; PMCID: PMC7429266.
      Citations: 26     Fields:    Translation:Humans
    65. Pabon E, MacKillop J, Palmer AA, de Wit H. Multidimensional latent structure of risk-related phenotypes in healthy young adults. Exp Clin Psychopharmacol. 2020 Feb; 28(1):55-64. PMID: 30998058; PMCID: PMC7233128.
      Citations: 2     Fields:    Translation:Humans
    66. Van Hedger K, Bershad AK, Lee R, de Wit H. Effects of Intranasal Oxytocin on Stress-Induced Cigarette Craving in Daily Smokers. Nicotine Tob Res. 2020 01 27; 22(1):89-95. PMID: 30085292; PMCID: PMC7297012.
      Citations: 10     Fields:    Translation:Humans
    67. Bershad AK, Preller KH, Lee R, Keedy S, Wren-Jarvis J, Bremmer MP, de Wit H. Preliminary Report on the Effects of a Low Dose of LSD on Resting-State Amygdala Functional Connectivity. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 04; 5(4):461-467. PMID: 32033922; PMCID: PMC7150630.
      Citations: 43     Fields:    Translation:Humans
    68. Weafer J, Phan KL, de Wit H. Poor inhibitory control is associated with greater stimulation and less sedation following alcohol. Psychopharmacology (Berl). 2020 Mar; 237(3):825-832. PMID: 31832721; PMCID: PMC7039753.
      Citations: 7     Fields:    Translation:Humans
    69. Meyre D, Mohamed S, Gray JC, Weafer J, MacKillop J, de Wit H. Association between impulsivity traits and body mass index at the observational and genetic epidemiology level. Sci Rep. 2019 11 26; 9(1):17583. PMID: 31772290; PMCID: PMC6879509.
      Citations: 4     Fields:    Translation:Humans
    70. Langenecker SA, Kling LR, Crane NA, Gorka SM, Nusslock R, Damme KSF, Weafer J, de Wit H, Phan KL. Anticipation of monetary reward in amygdala, insula, caudate are predictors of pleasure sensitivity to d-Amphetamine administration. Drug Alcohol Depend. 2020 01 01; 206:107725. PMID: 31757518; PMCID: PMC6980714.
      Citations: 11     Fields:    Translation:Humans
    71. Doss MK, Weafer J, Gallo DA, de Wit H. ?9-Tetrahydrocannabinol During Encoding Impairs Perceptual Details yet Spares Context Effects on Episodic Memory. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 01; 5(1):110-118. PMID: 31668830; PMCID: PMC6954333.
      Citations: 7     Fields:    Translation:Humans
    72. Pabon E, de Wit H. Developing a phone-based measure of impairment after acute oral ?9-tetrahydrocannabinol. J Psychopharmacol. 2019 09; 33(9):1160-1169. PMID: 31407943; PMCID: PMC7303896.
      Citations: 7     Fields:    Translation:HumansAnimals
    73. de Wit H, Bershad AK. MDMA enhances pleasantness of affective touch. Neuropsychopharmacology. 2020 01; 45(1):217-239. PMID: 31391575; PMCID: PMC6879524.
      Citations: 6     Fields:    Translation:Humans
    74. Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong JS, Ip HF, van der Zee MD, Bartels M, Day FR, Fontanillas P, Elson SL, 23andMe Research Team, de Wit H, Davis LK, MacKillop J, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Paus T, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Gillespie NA, Derks EM, Vink JM, Pasman JA, Mägi R, Ramos-Quiroga JA, Ribases M, Munafò MR. Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability. Nat Neurosci. 2019 Jul; 22(7):1196. PMID: 31168101.
      Citations: 5     Fields:    
    75. Schepers ST, Arndt DL, Rogers RD, Hedeker D, de Wit H. Subjective responses to amphetamine in young adults with previous mood elevation experiences. Psychopharmacology (Berl). 2019 Nov; 236(11):3363-3370. PMID: 31209507; PMCID: PMC7053220.
      Citations: 4     Fields:    Translation:Humans
    76. Bershad AK, Schepers ST, Bremmer MP, Lee R, de Wit H. Acute Subjective and Behavioral Effects of Microdoses of Lysergic Acid Diethylamide in Healthy Human Volunteers. Biol Psychiatry. 2019 11 15; 86(10):792-800. PMID: 31331617; PMCID: PMC6814527.
      Citations: 75     Fields:    Translation:HumansAnimalsCTClinical Trials
    77. Van Hedger K, Kushner MJ, Lee R, de Wit H. Oxytocin Reduces Cigarette Consumption in Daily Smokers. Nicotine Tob Res. 2019 05 21; 21(6):799-804. PMID: 29701814; PMCID: PMC6784409.
      Citations: 11     Fields:    Translation:Humans
    78. Weafer J, Van Hedger K, Keedy SK, Nwaokolo N, de Wit H. Methamphetamine acutely alters frontostriatal resting state functional connectivity in healthy young adults. Addict Biol. 2020 05; 25(3):e12775. PMID: 31099141; PMCID: PMC6527344.
      Citations: 21     Fields:    Translation:Humans
    79. Cryan JF, de Wit H. The gut microbiome in psychopharmacology and psychiatry. Psychopharmacology (Berl). 2019 05; 236(5):1407-1409. PMID: 31172224.
      Citations: 4     Fields:    
    80. Bershad AK, Van Hedger K, McGlone F, Walker SC, de Wit H, Mayo LM. Effects of MDMA on attention to positive social cues and pleasantness of affective touch. Neuropsychopharmacology. 2019 09; 44(10):1698-1705. PMID: 31042696; PMCID: PMC6785008.
      Citations: 37     Fields:    Translation:Humans
    81. Weafer J, Crane NA, Gorka SM, Phan KL, de Wit H. Neural correlates of inhibition and reward are negatively associated. Neuroimage. 2019 08 01; 196:188-194. PMID: 30974242; PMCID: PMC6559844.
      Citations: 19     Fields:    Translation:Humans
    82. Gray JC, Sanchez-Roige S, de Wit H, MacKillop J, Palmer AA. Genomic basis of delayed reward discounting. Behav Processes. 2019 May; 162:157-161. PMID: 30876880; PMCID: PMC6980721.
      Citations: 5     Fields:    Translation:HumansAnimals
    83. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA, Abecasis GR. Publisher Correction: Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2019 Mar; 22(3):503. PMID: 30622366.
      Citations:    Fields:    
    84. Sanchez-Roige S, Fontanillas P, Elson SL, Gray JC, de Wit H, MacKillop J, Palmer AA. Genome-Wide Association Studies of Impulsive Personality Traits (BIS-11 and UPPS-P) and Drug Experimentation in up to 22,861 Adult Research Participants Identify Loci in the CACNA1I and CADM2 genes. J Neurosci. 2019 03 27; 39(13):2562-2572. PMID: 30718321; PMCID: PMC6435820.
      Citations: 78     Fields:    Translation:Humans
    85. Van Hedger K, Keedy SK, Schertz KE, Berman MG, de Wit H. Effects of methamphetamine on neural responses to visual stimuli. Psychopharmacology (Berl). 2019 Jun; 236(6):1741-1748. PMID: 30604184; PMCID: PMC6606378.
      Citations: 5     Fields:    Translation:Humans
    86. Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Murray AD, Nurnberger JI, Palotie A, Preuss U, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A, Gäbel W, Männistö S, Müller-Myhsok B, Räikkönen K, Nöthen MM. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nat Neurosci. 2018 12; 21(12):1656-1669. PMID: 30482948; PMCID: PMC6430207.
      Citations: 364     Fields:    Translation:Humans
    87. MacKillop J, Gray JC, Weafer J, Sanchez-Roige S, Palmer AA, de Wit H. Genetic influences on delayed reward discounting: A genome-wide prioritized subset approach. Exp Clin Psychopharmacol. 2019 Feb; 27(1):29-37. PMID: 30265060; PMCID: PMC6908809.
      Citations: 8     Fields:    Translation:Humans
    88. Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong JS, Ip HF, van der Zee MD, Bartels M, Day FR, Fontanillas P, Elson SL, 23andMe Research Team, de Wit H, Davis LK, MacKillop J, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Paus T, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Gillespie NA, Derks EM, Vink JM, Pasman JA, Mägi R, Ramos-Quiroga JA, Ribases M, Munafò MR. GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Nat Neurosci. 2018 09; 21(9):1161-1170. PMID: 30150663; PMCID: PMC6386176.
      Citations: 233     Fields:    Translation:Humans
    89. Doss MK, Weafer J, Ruiz NA, Gallo DA, De Wit H. Alcohol and pharmacologically similar sedatives impair encoding and facilitate consolidation of both recollection and familiarity in episodic memory. Cogn Neurosci. 2018 Jul - Oct; 9(3-4):89-99. PMID: 30044718; PMCID: PMC6309693.
      Citations: 7     Fields:    Translation:Humans
    90. Weafer J, Ross TJ, O'Connor S, Stein EA, de Wit H, Childs E. Striatal activity correlates with stimulant-like effects of alcohol in healthy volunteers. Neuropsychopharmacology. 2018 12; 43(13):2532-2538. PMID: 30093699; PMCID: PMC6224577.
      Citations: 14     Fields:    Translation:Humans
    91. Vena A, King A, Lee R, de Wit H. Intranasal Oxytocin Does Not Modulate Responses to Alcohol in Social Drinkers. Alcohol Clin Exp Res. 2018 09; 42(9):1725-1734. PMID: 29917245; PMCID: PMC6120762.
      Citations: 12     Fields:    Translation:Humans
    92. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA, Abecasis GR. Publisher Correction: Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2018 Jul; 21(7):1018. PMID: 29752479.
      Citations:    Fields:    
    93. de Wit H, Epstein DH, Preston KL. Does human language limit translatability of clinical and preclinical addiction research? Neuropsychopharmacology. 2018 09; 43(10):1985-1988. PMID: 29844475; PMCID: PMC6098131.
      Citations: 11     Fields:    Translation:HumansAnimals
    94. Doss MK, Weafer J, Gallo DA, de Wit H. ?9-Tetrahydrocannabinol at Retrieval Drives False Recollection of Neutral and Emotional Memories. Biol Psychiatry. 2018 11 15; 84(10):743-750. PMID: 29884456.
      Citations: 17     Fields:    Translation:Humans
    95. Bershad AK, Miller MA, Norman GJ, de Wit H. Effects of opioid- and non-opioid analgesics on responses to psychosocial stress in humans. Horm Behav. 2018 06; 102:41-47. PMID: 29673620; PMCID: PMC6004330.
      Citations: 20     Fields:    Translation:Humans
    96. Crane NA, Gorka SM, Weafer J, Langenecker SA, de Wit H, Phan KL. Neural activation to monetary reward is associated with amphetamine reward sensitivity. Neuropsychopharmacology. 2018 07; 43(8):1738-1744. PMID: 29581536; PMCID: PMC6006344.
      Citations: 13     Fields:    Translation:Humans
    97. de Wit H, Sayette M. Considering the context: social factors in responses to drugs in humans. Psychopharmacology (Berl). 2018 04; 235(4):935-945. PMID: 29470605; PMCID: PMC5871591.
      Citations: 23     Fields:    Translation:HumansAnimals
    98. Curran HV, Nutt D, de Wit H. Psychedelics and related drugs: therapeutic possibilities, mechanisms and regulation. Psychopharmacology (Berl). 2018 02; 235(2):373-375. PMID: 29445838.
      Citations: 11     Fields:    Translation:HumansAnimals
    99. Bershad AK, Ruiz NA, de Wit H. Effects of Buprenorphine on Responses to Emotional Stimuli in Individuals with a Range of Mood Symptomatology. Int J Neuropsychopharmacol. 2018 02 01; 21(2):120-127. PMID: 29025085; PMCID: PMC5793829.
      Citations: 8     Fields:    Translation:Humans
    100. Van Hedger K, Keedy SK, de Wit H, Mayo LM, Heilig M. Neural responses to cues paired with methamphetamine in healthy volunteers. Neuropsychopharmacology. 2018 07; 43(8):1732-1737. PMID: 29463908; PMCID: PMC6006246.
      Citations: 8     Fields:    Translation:Humans
    101. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA, Abecasis GR. Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2018 01; 21(1):16-18. PMID: 29230059; PMCID: PMC6984001.
      Citations: 69     Fields:    Translation:Humans
    102. Gray JC, MacKillop J, Weafer J, Hernandez KM, Gao J, Palmer AA, de Wit H. Genetic analysis of impulsive personality traits: Examination of a priori candidates and genome-wide variation. Psychiatry Res. 2018 01; 259:398-404. PMID: 29120849; PMCID: PMC5742029.
      Citations: 21     Fields:    Translation:Humans
    103. Crane NA, Gorka SM, Weafer J, Langenecker SA, de Wit H, Phan KL. Preliminary Evidence for Disrupted Nucleus Accumbens Reactivity and Connectivity to Reward in Binge Drinkers. Alcohol Alcohol. 2017 Nov 01; 52(6):647-654. PMID: 29016710; PMCID: PMC5860287.
      Citations: 15     Fields:    Translation:Humans
    104. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA. Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry. Addict Biol. 2019 01; 24(1):121-131. PMID: 29058377; PMCID: PMC6988186.
      Citations: 65     Fields:    Translation:HumansPHPublic Health
    105. Palmisano AN, Hudd EC, McQuade CM, de Wit H, Astur RS. The effects of nicotine on conditioning, extinction, and reinstatement in humans. Addict Behav. 2018 Feb; 77:51-58. PMID: 28957728.
      Citations: 5     Fields:    Translation:Humans
    106. Van Hedger K, Bershad AK, de Wit H. Pharmacological challenge studies with acute psychosocial stress. Psychoneuroendocrinology. 2017 Nov; 85:123-133. PMID: 28858691; PMCID: PMC5623124.
      Citations: 10     Fields:    Translation:Humans
    107. Doss MK, Weafer J, Gallo DA, de Wit H. MDMA Impairs Both the Encoding and Retrieval of Emotional Recollections. Neuropsychopharmacology. 2018 03; 43(4):791-800. PMID: 28825422; PMCID: PMC5809786.
      Citations: 22     Fields:    Translation:Humans
    108. Weafer J, Lyon N, Hedeker D, de Wit H. Sweet taste liking is associated with subjective response to amphetamine in women but not men. Psychopharmacology (Berl). 2017 Nov; 234(21):3185-3194. PMID: 28762072; PMCID: PMC5660927.
      Citations: 11     Fields:    Translation:HumansAnimals
    109. Bidwell LC, Gray JC, Weafer J, Palmer AA, de Wit H, MacKillop J. Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):458-466. PMID: 28512748; PMCID: PMC5690554.
      Citations: 16     Fields:    Translation:Humans
    110. Arndt DL, de Wit H. Cannabidiol Does Not Dampen Responses to Emotional Stimuli in Healthy Adults. Cannabis Cannabinoid Res. 2017; 2(1):105-113. PMID: 28861510; PMCID: PMC5569582.
      Citations: 25     Fields:    
    111. Childs E, Lutz JA, de Wit H. Dose-related effects of delta-9-THC on emotional responses to acute psychosocial stress. Drug Alcohol Depend. 2017 08 01; 177:136-144. PMID: 28599212; PMCID: PMC6349031.
      Citations: 59     Fields:    Translation:Humans
    112. Cryan JF, de Wit H. Special issue: recognizing the lifetime scientific contributions of Athina Markou. Psychopharmacology (Berl). 2017 05; 234(9-10):1311-1313. PMID: 28421256; PMCID: PMC5473252.
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    113. Bershad AK, Miller MA, de Wit H. MDMA does not alter responses to the Trier Social Stress Test in humans. Psychopharmacology (Berl). 2017 Jul; 234(14):2159-2166. PMID: 28432376; PMCID: PMC5984654.
      Citations: 6     Fields:    Translation:Humans
    114. Weafer J, Gorka SM, Hedeker D, Dzemidzic M, Kareken DA, Phan KL, de Wit H. Associations Between Behavioral and Neural Correlates of Inhibitory Control and Amphetamine Reward Sensitivity. Neuropsychopharmacology. 2017 Aug; 42(9):1905-1913. PMID: 28303900; PMCID: PMC5520786.
      Citations: 20     Fields:    Translation:Humans
    115. Childs E, Astur RS, de Wit H. Virtual reality conditioned place preference using monetary reward. Behav Brain Res. 2017 03 30; 322(Pt A):110-114. PMID: 28108321; PMCID: PMC5335910.
      Citations: 7     Fields:    Translation:Humans
    116. Miller MA, Bershad A, King AC, Lee R, de Wit H. Intranasal oxytocin dampens cue-elicited cigarette craving in daily smokers: a pilot study. Behav Pharmacol. 2016 12; 27(8):697-703. PMID: 27661192; PMCID: PMC5089916.
      Citations: 18     Fields:    Translation:Humans
    117. Shaham Y, de Wit H. Lost in Translation: CRF1 Receptor Antagonists and Addiction Treatment. Neuropsychopharmacology. 2016 11; 41(12):2795-2797. PMID: 27312404; PMCID: PMC5061894.
      Citations: 32     Fields:    Translation:Humans
    118. Childs E, de Wit H. Alcohol-induced place conditioning in moderate social drinkers. Addiction. 2016 12; 111(12):2157-2165. PMID: 27447940; PMCID: PMC5226878.
      Citations: 13     Fields:    Translation:Humans
    119. Bershad AK, Miller MA, Baggott MJ, de Wit H. The effects of MDMA on socio-emotional processing: Does MDMA differ from other stimulants? J Psychopharmacol. 2016 12; 30(12):1248-1258. PMID: 27562198; PMCID: PMC8753974.
      Citations: 54     Fields:    Translation:Humans
    120. Cavallo JS, Mayo LM, de Wit H. Acquisition of Conditioning between Methamphetamine and Cues in Healthy Humans. PLoS One. 2016; 11(8):e0161541. PMID: 27548681; PMCID: PMC4993385.
      Citations: 2     Fields:    Translation:Humans
    121. Francis SM, Kirkpatrick MG, de Wit H, Jacob S. Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration. Psychoneuroendocrinology. 2016 12; 74:92-100. PMID: 27592327.
      Citations: 23     Fields:    Translation:Humans
    122. MacKillop J, Weafer J, C Gray J, Oshri A, Palmer A, de Wit H. The latent structure of impulsivity: impulsive choice, impulsive action, and impulsive personality traits. Psychopharmacology (Berl). 2016 Sep; 233(18):3361-70. PMID: 27449350; PMCID: PMC5204128.
      Citations: 166     Fields:    Translation:Humans
    123. Childs E, Bershad AK, de Wit H. Effects of d-amphetamine upon psychosocial stress responses. J Psychopharmacol. 2016 07; 30(7):608-15. PMID: 27235381.
      Citations: 7     Fields:    Translation:Humans
    124. Cavallo JS, Ruiz NA, de Wit H. Extinction of Conditioned Responses to Methamphetamine-Associated Stimuli in Healthy Humans. Psychopharmacology (Berl). 2016 07; 233(13):2489-502. PMID: 27113223; PMCID: PMC4909474.
      Citations: 3     Fields:    Translation:HumansAnimals
    125. Steckler T, Curran HV, de Wit H, Howes O, Hoyer D, Lucki I, Miczek KA, Morrow AL, Price LH, Robbins TW. Editorial: Reporting guidelines for psychopharmacology. Psychopharmacology (Berl). 2016 Apr; 233(7):1131-4. PMID: 26915651.
      Citations: 2     Fields:    
    126. Mayo LM, de Wit H. Acquisition of Conditioned Responses to a Novel Alcohol-Paired Cue in Social Drinkers. J Stud Alcohol Drugs. 2016 Mar; 77(2):317-26. PMID: 26997190; PMCID: PMC4803664.
      Citations: 12     Fields:    Translation:Humans
    127. Bershad AK, Weafer JJ, Kirkpatrick MG, Wardle MC, Miller MA, de Wit H. Oxytocin receptor gene variation predicts subjective responses to MDMA. Soc Neurosci. 2016 12; 11(6):592-9. PMID: 26787430; PMCID: PMC4988944.
      Citations: 19     Fields:    Translation:Humans
    128. Smith CT, Weafer J, Cowan RL, Kessler RM, Palmer AA, de Wit H, Zald DH. Individual differences in timing of peak positive subjective responses to d-amphetamine: Relationship to pharmacokinetics and physiology. J Psychopharmacol. 2016 Apr; 30(4):330-43. PMID: 26880226; PMCID: PMC5049703.
      Citations: 7     Fields:    Translation:Humans
    129. Wardle MC, Bershad AK, de Wit H. Naltrexone alters the processing of social and emotional stimuli in healthy adults. Soc Neurosci. 2016 12; 11(6):579-91. PMID: 26710657; PMCID: PMC4958027.
      Citations: 21     Fields:    Translation:Humans
    130. Weafer J, Gallo DA, de Wit H. Acute Effects of Alcohol on Encoding and Consolidation of Memory for Emotional Stimuli. J Stud Alcohol Drugs. 2016 Jan; 77(1):86-94. PMID: 26751358; PMCID: PMC4711324.
      Citations: 14     Fields:    Translation:Humans
    131. Temple JL, Ziegler AM, Martin C, de Wit H. Subjective Responses to Caffeine Are Influenced by Caffeine Dose, Sex, and Pubertal Stage. J Caffeine Res. 2015 Dec 01; 5(4):167-175. PMID: 26649252; PMCID: PMC4663646.
      Citations: 14     
    132. Wardle MC, Marcus BA, de Wit H. A Preliminary Investigation of Individual Differences in Subjective Responses to D-Amphetamine, Alcohol, and Delta-9-Tetrahydrocannabinol Using a Within-Subjects Randomized Trial. PLoS One. 2015; 10(10):e0140501. PMID: 26513587; PMCID: PMC4626040.
      Citations: 14     Fields:    Translation:Humans
    133. de Wit H, Gorka SM, Phan KL. The Ups and Downs of 3,4-Methylenedioxymethamphetamine: Linking Subjective Effects to Spontaneous Brain Function. Biol Psychiatry. 2015 Oct 15; 78(8):519-21. PMID: 26386625.
      Citations: 1     Fields:    Translation:Humans
    134. Kirkpatrick MG, Goldenson NI, Kapadia N, Kahler CW, de Wit H, Swift RM, McGeary JE, Sussman S, Leventhal AM. Emotional traits predict individual differences in amphetamine-induced positive mood in healthy volunteers. Psychopharmacology (Berl). 2016 Jan; 233(1):89-97. PMID: 26429791; PMCID: PMC4703469.
      Citations: 7     Fields:    Translation:Humans
    135. VanderBroek L, Acker J, Palmer AA, de Wit H, MacKillop J. Interrelationships among parental family history of substance misuse, delay discounting, and personal substance use. Psychopharmacology (Berl). 2016 Jan; 233(1):39-48. PMID: 26395990; PMCID: PMC4830143.
      Citations: 32     Fields:    Translation:Humans
    136. de Wit HM, Engwerda EE, Tack CJ, de Galan BE. Insulin administered by needle-free jet injection corrects marked hyperglycaemia faster in overweight or obese patients with diabetes. Diabetes Obes Metab. 2015 Nov; 17(11):1093-9. PMID: 26259978.
      Citations: 9     Fields:    Translation:Humans
    137. Bershad AK, Seiden JA, de Wit H. Effects of buprenorphine on responses to social stimuli in healthy adults. Psychoneuroendocrinology. 2016 Jan; 63:43-9. PMID: 26409030; PMCID: PMC4695221.
      Citations: 26     Fields:    Translation:Humans
    138. de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Amin N, Gordon SD, Hansell NK, Hart AB, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abdellaoui A, Abecasis GR, Adkins DE, Agrawal A, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Smith GD, Davies G, de Wit H, Ding J, Engelhardt BE, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Mbarek H, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Nivard MG, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Generation Scotland, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Wilson JF, Bierut LJ, Hettema JM, Grabe HJ, Penninx BW, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, McGue M, Martin NG, Boomsma DI, van den Berg SM, Esko T, Seppälä I, Allik J, Eriksson JG, Lehtimäki T, Pulkki-Råback L, Räikkönen K, Keltikangas-Järvinen L, Terracciano A. Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behav Genet. 2016 Mar; 46(2):170-82. PMID: 26362575; PMCID: PMC4751159.
      Citations: 69     Fields:    Translation:Humans
    139. Miller MA, Bershad AK, de Wit H. Drug effects on responses to emotional facial expressions: recent findings. Behav Pharmacol. 2015 Sep; 26(6):571-9. PMID: 26226144; PMCID: PMC4905685.
      Citations: 11     Fields:    Translation:Humans
    140. Genetics of Personality Consortium, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Amin N, Gordon SD, Hansell NK, Hart AB, Huffman JE, Konte B, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abecasis GR, Adkins DE, Agrawal A, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Davey Smith G, Davies G, de Wit H, Ding J, Engelhardt BE, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Wilson JF, Bierut LJ, Hettema JM, Grabe HJ, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, McGue M, Penninx BW, Martin NG, Boomsma DI, van den Berg SM, Esko T, Seppälä I, Lahti J, Allik J, Eriksson JG, Lehtimäki T, Pulkki-Råback L, Räikkönen K, Keltikangas-Järvinen L, Terracciano A. Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA Psychiatry. 2015 Jul; 72(7):642-50. PMID: 25993607; PMCID: PMC4667957.
      Citations: 126     Fields:    Translation:Humans
    141. Kirkpatrick MG, Seiden JA, de Wit H, Bershad AK. Effects of acute doses of prosocial drugs methamphetamine and alcohol on plasma oxytocin levels. J Clin Psychopharmacol. 2015 Jun; 35(3):308-12. PMID: 25853370; PMCID: PMC4414800.
      Citations: 15     Fields:    Translation:Humans
    142. Weafer J, De Arcangelis J, de Wit H. Sex differences in behavioral impulsivity in at-risk and non-risk drinkers. Front Psychiatry. 2015; 6:72. PMID: 26029121; PMCID: PMC4429551.
      Citations: 11     
    143. Baggott MJ, Kirkpatrick MG, Bedi G, de Wit H. Intimate insight: MDMA changes how people talk about significant others. J Psychopharmacol. 2015 Jun; 29(6):669-77. PMID: 25922420; PMCID: PMC4698152.
      Citations: 32     Fields:    Translation:Humans
    144. Yarosh HL, Meda SA, de Wit H, Hart AB, Pearlson GD. Multivariate analysis of subjective responses to d-amphetamine in healthy volunteers finds novel genetic pathway associations. Psychopharmacology (Berl). 2015 Aug; 232(15):2781-94. PMID: 25843748; PMCID: PMC4504822.
      Citations: 5     Fields:    Translation:Humans
    145. Kirkpatrick M, Delton AW, Robertson TE, de Wit H. Prosocial effects of MDMA: A measure of generosity. J Psychopharmacol. 2015 Jun; 29(6):661-8. PMID: 25735993.
      Citations: 29     Fields:    Translation:Humans
    146. Ballard ME, Weafer J, Gallo DA, de Wit H. Effects of acute methamphetamine on emotional memory formation in humans: encoding vs consolidation. PLoS One. 2015; 10(2):e0117062. PMID: 25679982; PMCID: PMC4332474.
      Citations: 7     Fields:    Translation:Humans
    147. Mayo LM, de Wit H. Acquisition of responses to a methamphetamine-associated cue in healthy humans: self-report, behavioral, and psychophysiological measures. Neuropsychopharmacology. 2015 Jun; 40(7):1734-41. PMID: 25601231; PMCID: PMC4915257.
      Citations: 25     Fields:    Translation:Humans
    148. Tasali E, Leproult R, Stuhr KL, Doncheck E, de Wit H, Hillard CJ, Van Cauter E, Hanlon EC. Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. J Clin Endocrinol Metab. 2015 Jan; 100(1):220-6. PMID: 25368979; PMCID: PMC5399498.
      Citations: 44     Fields:    Translation:Humans
    149. Gorka SM, Fitzgerald DA, de Wit H, Phan KL. Cannabinoid modulation of amygdala subregion functional connectivity to social signals of threat. Int J Neuropsychopharmacol. 2014 Dec 28; 18(3). PMID: 25548107; PMCID: PMC4360235.
      Citations: 18     Fields:    Translation:Humans
    150. Bershad AK, Jaffe JH, Childs E, de Wit H. Opioid partial agonist buprenorphine dampens responses to psychosocial stress in humans. Psychoneuroendocrinology. 2015 Feb; 52:281-8. PMID: 25544740; PMCID: PMC4297554.
      Citations: 39     Fields:    Translation:Humans
    151. Kirkpatrick MG, de Wit H. MDMA: a social drug in a social context. Psychopharmacology (Berl). 2015 Mar; 232(6):1155-63. PMID: 25281223; PMCID: PMC4339498.
      Citations: 25     Fields:    Translation:Humans
    152. Gorka SM, Fitzgerald DA, de Wit H, Angstadt M, Phan KL. Opioid modulation of resting-state anterior cingulate cortex functional connectivity. J Psychopharmacol. 2014 Dec; 28(12):1115-24. PMID: 25237122; PMCID: PMC5613932.
      Citations: 17     Fields:    Translation:Humans
    153. Childs E, White TL, de Wit H. Personality traits modulate emotional and physiological responses to stress. Behav Pharmacol. 2014 Sep; 25(5-6):493-502. PMID: 25036730; PMCID: PMC4119514.
      Citations: 24     Fields:    Translation:Humans
    154. Weafer J, Burkhardt A, de Wit H. Sweet taste liking is associated with impulsive behaviors in humans. Front Behav Neurosci. 2014; 8:228. PMID: 24987343; PMCID: PMC4060557.
      Citations: 13     
    155. Wardle MC, Fitzgerald DA, Angstadt M, Rabinak CA, de Wit H, Phan KL. Effects of oxycodone on brain responses to emotional images. Psychopharmacology (Berl). 2014 Nov; 231(22):4403-15. PMID: 24800897; PMCID: PMC6720110.
      Citations: 9     Fields:    Translation:Humans
    156. Childs E, de Wit H. Regular exercise is associated with emotional resilience to acute stress in healthy adults. Front Physiol. 2014; 5:161. PMID: 24822048; PMCID: PMC4013452.
      Citations: 89     
    157. Kirkpatrick MG, Francis SM, Lee R, de Wit H, Jacob S. Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans. Psychoneuroendocrinology. 2014 Aug; 46:23-31. PMID: 24882155; PMCID: PMC4088952.
      Citations: 41     Fields:    Translation:Humans
    158. Wardle MC, de Wit H. MDMA alters emotional processing and facilitates positive social interaction. Psychopharmacology (Berl). 2014 Oct; 231(21):4219-29. PMID: 24728603; PMCID: PMC4194242.
      Citations: 47     Fields:    Translation:Humans
    159. Hart AB, Gamazon ER, Engelhardt BE, Sklar P, Hultman CM, Sullivan PF, Neale BM, Faraone SV, Psychiatric Genomics Consortium: ADHD Subgroup, de Wit H, Cox NJ, Palmer AA, Kähler AK. Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):5968-73. PMID: 24711425; PMCID: PMC4000861.
      Citations: 14     Fields:    Translation:Humans
    160. Bedi G, Cecchi GA, Slezak DF, Carrillo F, Sigman M, de Wit H. A window into the intoxicated mind? Speech as an index of psychoactive drug effects. Neuropsychopharmacology. 2014 Sep; 39(10):2340-8. PMID: 24694926; PMCID: PMC4138742.
      Citations: 42     Fields:    Translation:Humans
    161. Wardle MC, Kirkpatrick MG, de Wit H. 'Ecstasy' as a social drug: MDMA preferentially affects responses to emotional stimuli with social content. Soc Cogn Affect Neurosci. 2014 Aug; 9(8):1076-81. PMID: 24682132; PMCID: PMC4127030.
      Citations: 27     Fields:    Translation:Humans
    162. Kirkpatrick MG, Baggott MJ, Mendelson JE, Galloway GP, Liechti ME, de Wit H, Hysek CM. MDMA effects consistent across laboratories. Psychopharmacology (Berl). 2014 Oct; 231(19):3899-905. PMID: 24633447; PMCID: PMC4161650.
      Citations: 28     Fields:    Translation:Humans
    163. Clark DB, de Wit H, Iacono WG. ADHD, impulsivity and alcohol abuse: methods, results, and implications. Exp Clin Psychopharmacol. 2014 Apr; 22(2):141-3. PMID: 24611836; PMCID: PMC4141644.
      Citations:    Fields:    Translation:Humans
    164. de Wit H, Hoek JB. Farewell to Drs. Ivan Diamond and T.-K. Li. Alcohol Clin Exp Res. 2014 Jul; 38(7):1821. PMID: 24588447.
      Citations:    Fields:    Translation:Humans
    165. Weafer J, Gallo DA, de Wit H. Amphetamine fails to alter cued recollection of emotional images: study of encoding, retrieval, and state-dependency. PLoS One. 2014; 9(2):e90423. PMID: 24587355; PMCID: PMC3937372.
      Citations: 6     Fields:    Translation:Humans
    166. Gallo DA, de Wit H, Ballard ME. Amphetamine increases errors during episodic memory retrieval. J Clin Psychopharmacol. 2014 Feb; 34(1):85-92. PMID: 24135845; PMCID: PMC4244906.
      Citations: 17     Fields:    Translation:Humans
    167. Kirkpatrick MG, Lee R, Wardle MC, Jacob S, de Wit H. Effects of MDMA and Intranasal oxytocin on social and emotional processing. Neuropsychopharmacology. 2014 Jun; 39(7):1654-63. PMID: 24448644; PMCID: PMC4023138.
      Citations: 68     Fields:    Translation:Humans
    168. Frye CG, Wardle MC, Norman GJ, de Wit H. MDMA decreases the effects of simulated social rejection. Pharmacol Biochem Behav. 2014 Feb; 117:1-6. PMID: 24316346; PMCID: PMC3910346.
      Citations: 42     Fields:    Translation:Humans
    169. Weafer J, de Wit H. Sex differences in impulsive action and impulsive choice. Addict Behav. 2014 Nov; 39(11):1573-1579. PMID: 24286704; PMCID: PMC4012004.
      Citations: 98     Fields:    Translation:HumansAnimals
    170. Weafer J, Baggott MJ, de Wit H. Test-retest reliability of behavioral measures of impulsive choice, impulsive action, and inattention. Exp Clin Psychopharmacol. 2013 Dec; 21(6):475-81. PMID: 24099351; PMCID: PMC4266373.
      Citations: 96     Fields:    Translation:HumansCTClinical Trials
    171. Weafer J, de Wit H. Inattention, impulsive action, and subjective response to D-amphetamine. Drug Alcohol Depend. 2013 Nov 01; 133(1):127-33. PMID: 23790566; PMCID: PMC3786022.
      Citations: 23     Fields:    Translation:Humans
    172. Heinz AJ, de Wit H, Lilje TC, Kassel JD. The combined effects of alcohol, caffeine, and expectancies on subjective experience, impulsivity, and risk-taking. Exp Clin Psychopharmacol. 2013 Jun; 21(3):222-34. PMID: 23750693; PMCID: PMC4354945.
      Citations: 29     Fields:    Translation:Humans
    173. Kirkpatrick MG, de Wit H. In the company of others: social factors alter acute alcohol effects. Psychopharmacology (Berl). 2013 Nov; 230(2):215-26. PMID: 23712603; PMCID: PMC3800265.
      Citations: 48     Fields:    Translation:Humans
    174. Napier TC, Herrold AA, de Wit H. Using conditioned place preference to identify relapse prevention medications. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt A):2081-6. PMID: 23680702; PMCID: PMC3815959.
      Citations: 39     Fields:    Translation:HumansAnimalsPHPublic Health
    175. Baggott MJ, Childs E, Hart AB, de Bruin E, Palmer AA, Wilkinson JE, de Wit H. Psychopharmacology of theobromine in healthy volunteers. Psychopharmacology (Berl). 2013 Jul; 228(1):109-18. PMID: 23420115; PMCID: PMC3672386.
      Citations: 36     Fields:    Translation:Humans
    176. Mayo LM, Fraser D, Childs E, Momenan R, Hommer DW, de Wit H, Heilig M. Conditioned preference to a methamphetamine-associated contextual cue in humans. Neuropsychopharmacology. 2013 May; 38(6):921-9. PMID: 23416857; PMCID: PMC3629404.
      Citations: 26     Fields:    Translation:Humans
    177. Kirkpatrick MG, Johanson CE, de Wit H. Personality and the acute subjective effects of d-amphetamine in humans. J Psychopharmacol. 2013 Mar; 27(3):256-64. PMID: 23343596; PMCID: PMC4241296.
      Citations: 20     Fields:    Translation:Humans
    178. Wardle MC, de Wit H, Penton-Voak I, Lewis G, Munafò MR. Lack of association between COMT and working memory in a population-based cohort of healthy young adults. Neuropsychopharmacology. 2013 Jun; 38(7):1253-63. PMID: 23337869; PMCID: PMC3656369.
      Citations: 32     Fields:    Translation:Humans
    179. Zorrilla EP, Heilig M, de Wit H, Shaham Y. Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. Drug Alcohol Depend. 2013 Mar 01; 128(3):175-86. PMID: 23294766; PMCID: PMC3596012.
      Citations: 51     Fields:    Translation:HumansAnimals
    180. Wardle MC, Hart AB, Palmer AA, de Wit H. Does COMT genotype influence the effects of d-amphetamine on executive functioning? Genes Brain Behav. 2013 Feb; 12(1):13-20. PMID: 23231539; PMCID: PMC3553317.
      Citations: 16     Fields:    Translation:Humans
    181. Morean ME, de Wit H, King AC, Sofuoglu M, Rueger SY, O'Malley SS. The drug effects questionnaire: psychometric support across three drug types. Psychopharmacology (Berl). 2013 May; 227(1):177-92. PMID: 23271193; PMCID: PMC3624068.
      Citations: 162     Fields:    Translation:Humans
    182. Conrad M, Wardle M, King A, de Wit H. Relationship of self-reported and acute stress to smoking in emerging adult smokers. J Clin Psychol. 2013 Jul; 69(7):710-7. PMID: 23280768; PMCID: PMC4795009.
      Citations: 3     Fields:    Translation:Humans
    183. Ballard ME, Gallo DA, de Wit H. Pre-encoding administration of amphetamine or THC preferentially modulates emotional memory in humans. Psychopharmacology (Berl). 2013 Apr; 226(3):515-29. PMID: 23224510; PMCID: PMC3595317.
      Citations: 10     Fields:    Translation:Humans
    184. Heinz AJ, Lilje TC, Kassel JD, de Wit H. Quantifying reinforcement value and demand for psychoactive substances in humans. Curr Drug Abuse Rev. 2012 Dec; 5(4):257-72. PMID: 23062106; PMCID: PMC3566575.
      Citations: 30     Fields:    Translation:Humans
    185. Hart AB, Engelhardt BE, Wardle MC, Sokoloff G, Stephens M, de Wit H, Palmer AA. Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). PLoS One. 2012; 7(8):e42646. PMID: 22952603; PMCID: PMC3429486.
      Citations: 55     Fields:    Translation:Humans
    186. Dlugos A, Childs E, Stuhr KL, Hillard CJ, de Wit H. Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans. Neuropsychopharmacology. 2012 Oct; 37(11):2416-27. PMID: 22763622; PMCID: PMC3442338.
      Citations: 97     Fields:    Translation:Humans
    187. Wardle MC, Treadway MT, de Wit H. Caffeine increases psychomotor performance on the effort expenditure for rewards task. Pharmacol Biochem Behav. 2012 Oct; 102(4):526-31. PMID: 22750066; PMCID: PMC3578395.
      Citations: 10     Fields:    Translation:Humans
    188. Metrik J, Kahler CW, Reynolds B, McGeary JE, Monti PM, Haney M, de Wit H, Rohsenow DJ. Balanced placebo design with marijuana: pharmacological and expectancy effects on impulsivity and risk taking. Psychopharmacology (Berl). 2012 Oct; 223(4):489-99. PMID: 22588253; PMCID: PMC3829473.
      Citations: 71     Fields:    Translation:Humans
    189. Ballard ME, Bedi G, de Wit H. Effects of delta-9-tetrahydrocannabinol on evaluation of emotional images. J Psychopharmacol. 2012 Oct; 26(10):1289-98. PMID: 22585232; PMCID: PMC3664416.
      Citations: 22     Fields:    Translation:Humans
    190. de Wit H, Phillips TJ. Do initial responses to drugs predict future use or abuse? Neurosci Biobehav Rev. 2012 Jul; 36(6):1565-76. PMID: 22542906; PMCID: PMC3372699.
      Citations: 111     Fields:    Translation:HumansAnimals
    191. Yip SW, Doherty J, Wakeley J, Saunders K, Tzagarakis C, de Wit H, Goodwin GM, Rogers RD. Reduced subjective response to acute ethanol administration among young men with a broad bipolar phenotype. Neuropsychopharmacology. 2012 Jul; 37(8):1808-15. PMID: 22491350; PMCID: PMC3376329.
      Citations: 18     Fields:    Translation:Humans
    192. Childs E, Roche DJ, King AC, de Wit H. Varenicline potentiates alcohol-induced negative subjective responses and offsets impaired eye movements. Alcohol Clin Exp Res. 2012 May; 36(5):906-14. PMID: 22339626; PMCID: PMC3342420.
      Citations: 28     Fields:    Translation:Humans
    193. Hart AB, de Wit H, Palmer AA. Genetic factors modulating the response to stimulant drugs in humans. Curr Top Behav Neurosci. 2012; 12:537-77. PMID: 22261702; PMCID: PMC3388157.
      Citations: 15     Fields:    Translation:Humans
    194. Palmer AA, de Wit H. Translational genetic approaches to substance use disorders: bridging the gap between mice and humans. Hum Genet. 2012 Jun; 131(6):931-9. PMID: 22170288; PMCID: PMC3352994.
      Citations: 8     Fields:    Translation:HumansAnimals
    195. Rabinak CA, Sripada CS, Angstadt M, de Wit H, Phan KL. Cannabinoid modulation of subgenual anterior cingulate cortex activation during experience of negative affect. J Neural Transm (Vienna). 2012 Jun; 119(6):701-7. PMID: 22160489; PMCID: PMC4242592.
      Citations: 14     Fields:    Translation:Humans
    196. Childs E, de Wit H. Contextual conditioning enhances the psychostimulant and incentive properties of d-amphetamine in humans. Addict Biol. 2013 Nov; 18(6):985-92. PMID: 22129527; PMCID: PMC4242554.
      Citations: 27     Fields:    Translation:HumansAnimals
    197. Wardle MC, Treadway MT, Mayo LM, Zald DH, de Wit H. Amping up effort: effects of d-amphetamine on human effort-based decision-making. J Neurosci. 2011 Nov 16; 31(46):16597-602. PMID: 22090487; PMCID: PMC3234999.
      Citations: 131     Fields:    Translation:Humans
    198. de Wit H. Sex hormones: a new treatment for cocaine abuse? Neuropsychopharmacology. 2011 Oct; 36(11):2155-6. PMID: 21918518; PMCID: PMC3176577.
      Citations: 3     Fields:    Translation:Animals
    199. Wardle MC, de Wit H. Effects of amphetamine on reactivity to emotional stimuli. Psychopharmacology (Berl). 2012 Mar; 220(1):143-53. PMID: 21947316; PMCID: PMC3277682.
      Citations: 26     Fields:    Translation:Humans
    200. Wardle MC, Yang A, de Wit H. Effect of d-amphetamine on post-error slowing in healthy volunteers. Psychopharmacology (Berl). 2012 Mar; 220(1):109-15. PMID: 21894485; PMCID: PMC4241763.
      Citations: 13     Fields:    Translation:Humans
    201. Childs E, O'Connor S, de Wit H. Bidirectional interactions between acute psychosocial stress and acute intravenous alcohol in healthy men. Alcohol Clin Exp Res. 2011 Oct; 35(10):1794-803. PMID: 21762177; PMCID: PMC3183385.
      Citations: 29     Fields:    Translation:Humans
    202. Ballard ME, Gallo DA, de Wit H. Psychoactive drugs and false memory: comparison of dextroamphetamine and d-9-tetrahydrocannabinol on false recognition. Psychopharmacology (Berl). 2012 Jan; 219(1):15-24. PMID: 21647577; PMCID: PMC4244903.
      Citations: 15     Fields:    Translation:Humans
    203. Wignall ND, de Wit H. Effects of nicotine on attention and inhibitory control in healthy nonsmokers. Exp Clin Psychopharmacol. 2011 Jun; 19(3):183-91. PMID: 21480731; PMCID: PMC4266322.
      Citations: 32     Fields:    Translation:Humans
    204. King AC, de Wit H, McNamara PJ, Cao D. Rewarding, stimulant, and sedative alcohol responses and relationship to future binge drinking. Arch Gen Psychiatry. 2011 Apr; 68(4):389-99. PMID: 21464363; PMCID: PMC4633413.
      Citations: 267     Fields:    Translation:Humans
    205. Bedi G, Preston KL, Epstein DH, Heishman SJ, Marrone GF, Shaham Y, de Wit H. Incubation of cue-induced cigarette craving during abstinence in human smokers. Biol Psychiatry. 2011 Apr 01; 69(7):708-11. PMID: 20817135; PMCID: PMC3027849.
      Citations: 132     Fields:    Translation:Humans
    206. Wardle M, Cederbaum K, de Wit H. Quantifying talk: developing reliable measures of verbal productivity. Behav Res Methods. 2011 Mar; 43(1):168-78. PMID: 21287128; PMCID: PMC3049967.
      Citations: 11     Fields:    Translation:Humans
    207. Wardle MC, de Wit H, Munafò MR. Effect of social stress during acute nicotine abstinence. Psychopharmacology (Berl). 2011 Nov; 218(1):39-48. PMID: 21234550; PMCID: PMC3094594.
      Citations: 16     Fields:    Translation:Humans
    208. Ballard ME, de Wit H. Combined effects of acute, very-low-dose ethanol and delta(9)-tetrahydrocannabinol in healthy human volunteers. Pharmacol Biochem Behav. 2011 Feb; 97(4):627-31. PMID: 21110996; PMCID: PMC3018238.
      Citations: 30     Fields:    Translation:Humans
    209. Mahler SV, de Wit H. Cue-reactors: individual differences in cue-induced craving after food or smoking abstinence. PLoS One. 2010 Nov 10; 5(11):e15475. PMID: 21085667; PMCID: PMC2978100.
      Citations: 41     Fields:    Translation:HumansCTClinical Trials
    210. Bedi G, Hyman D, de Wit H. Is ecstasy an "empathogen"? Effects of ±3,4-methylenedioxymethamphetamine on prosocial feelings and identification of emotional states in others. Biol Psychiatry. 2010 Dec 15; 68(12):1134-40. PMID: 20947066; PMCID: PMC2997873.
      Citations: 107     Fields:    Translation:Humans
    211. Yang A, Childs E, Palmer AA, de Wit H. More on ADORA. Psychopharmacology (Berl). 2010 Dec; 212(4):699-700. PMID: 20802997; PMCID: PMC4243305.
      Citations: 2     Fields:    Translation:Humans
    212. Comer SD, Bickel WK, Yi R, de Wit H, Higgins ST, Wenger GR, Johanson CE, Kreek MJ. Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society. Behav Pharmacol. 2010 Jul; 21(4):251-77. PMID: 20664330; PMCID: PMC2913311.
      Citations: 12     Fields:    Translation:Humans
    213. Yang A, Palmer AA, de Wit H. Genetics of caffeine consumption and responses to caffeine. Psychopharmacology (Berl). 2010 Aug; 211(3):245-57. PMID: 20532872; PMCID: PMC4242593.
      Citations: 115     Fields:    Translation:HumansAnimals
    214. Vaughn LK, Denning G, Stuhr KL, de Wit H, Hill MN, Hillard CJ. Endocannabinoid signalling: has it got rhythm? Br J Pharmacol. 2010 Jun; 160(3):530-43. PMID: 20590563; PMCID: PMC2931554.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    215. Hamidovic A, Dlugos A, Palmer AA, de Wit H. Catechol-O-methyltransferase val158met genotype modulates sustained attention in both the drug-free state and in response to amphetamine. Psychiatr Genet. 2010 Jun; 20(3):85-92. PMID: 20414144; PMCID: PMC2875066.
      Citations: 28     Fields:    Translation:HumansCTClinical Trials
    216. Lejuez CW, Magidson JF, Mitchell SH, Sinha R, Stevens MC, de Wit H. Behavioral and biological indicators of impulsivity in the development of alcohol use, problems, and disorders. Alcohol Clin Exp Res. 2010 Aug; 34(8):1334-45. PMID: 20491733; PMCID: PMC3182265.
      Citations: 141     Fields:    Translation:HumansAnimals
    217. Hamidovic A, Childs E, Conrad M, King A, de Wit H. Stress-induced changes in mood and cortisol release predict mood effects of amphetamine. Drug Alcohol Depend. 2010 Jun 01; 109(1-3):175-80. PMID: 20176450; PMCID: PMC2875349.
      Citations: 17     Fields:    Translation:Humans
    218. Childs E, Van Dam NT, de Wit H. Effects of acute progesterone administration upon responses to acute psychosocial stress in men. Exp Clin Psychopharmacol. 2010 Feb; 18(1):78-86. PMID: 20158297; PMCID: PMC4351805.
      Citations: 22     Fields:    Translation:Humans
    219. Hamidovic A, Dlugos A, Palmer AA, de Wit H. Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of D-amphetamine: an exploratory pharmacogenetic study using healthy volunteers. Behav Genet. 2010 Mar; 40(2):255-61. PMID: 20091113; PMCID: PMC4454285.
      Citations: 17     Fields:    Translation:Humans
    220. Childs E, Dlugos A, De Wit H. Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase. Psychophysiology. 2010 May 01; 47(3):550-9. PMID: 20070572; PMCID: PMC4242596.
      Citations: 58     Fields:    Translation:Humans
    221. Porcu P, O'Buckley TK, Alward SE, Song SC, Grant KA, de Wit H, Leslie Morrow A. Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans. Alcohol Clin Exp Res. 2010 Mar 01; 34(3):432-42. PMID: 20028362; PMCID: PMC2858248.
      Citations: 42     Fields:    Translation:HumansAnimals
    222. Hamidovic A, Dlugos A, Skol A, Palmer AA, de Wit H. Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants. Exp Clin Psychopharmacol. 2009 Dec; 17(6):374-83. PMID: 19968402; PMCID: PMC2879583.
      Citations: 55     Fields:    Translation:Humans
    223. Dlugos AM, Hamidovic A, Hodgkinson CA, Goldman D, Palmer AA, de Wit H. More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine. Neuropsychopharmacology. 2010 Feb; 35(3):613-22. PMID: 19890266; PMCID: PMC2945903.
      Citations: 17     Fields:    Translation:Humans
    224. Dlugos AM, Hamidovic A, Palmer AA, de Wit H. Further evidence of association between amphetamine response and SLC6A2 gene variants. Psychopharmacology (Berl). 2009 Oct; 206(3):501-11. PMID: 19727679; PMCID: PMC4242585.
      Citations: 12     Fields:    Translation:Humans
    225. Bedi G, Phan KL, Angstadt M, de Wit H. Effects of MDMA on sociability and neural response to social threat and social reward. Psychopharmacology (Berl). 2009 Nov; 207(1):73-83. PMID: 19680634; PMCID: PMC3328967.
      Citations: 101     Fields:    Translation:Humans
    226. Dlugos AM, Palmer AA, de Wit H. Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans. J Neural Transm (Vienna). 2009 Oct; 116(10):1323-34. PMID: 19657584; PMCID: PMC3653168.
      Citations: 21     Fields:    Translation:Humans
    227. Zacny JP, de Wit H. The prescription opioid, oxycodone, does not alter behavioral measures of impulsivity in healthy volunteers. Pharmacol Biochem Behav. 2009 Nov; 94(1):108-13. PMID: 19660489; PMCID: PMC2753749.
      Citations: 26     Fields:    Translation:HumansPHPublic Health
    228. Metrik J, Rohsenow DJ, Monti PM, McGeary J, Cook TA, de Wit H, Haney M, Kahler CW. Effectiveness of a marijuana expectancy manipulation: Piloting the balanced-placebo design for marijuana. Exp Clin Psychopharmacol. 2009 Aug; 17(4):217-25. PMID: 19653787; PMCID: PMC2810847.
      Citations: 52     Fields:    Translation:Humans
    229. de Wit H, Shaham Y. Incentive motivation, conditioning, stress, and neuropsychiatric disorders: a tribute to Jane Stewart. Biol Psychiatry. 2009 May 15; 65(10):827-8. PMID: 19398047; PMCID: PMC2716031.
      Citations:    Fields:    
    230. Childs E, de Wit H. Amphetamine-induced place preference in humans. Biol Psychiatry. 2009 May 15; 65(10):900-4. PMID: 19111278; PMCID: PMC2693956.
      Citations: 54     Fields:    Translation:Humans
    231. Hamidovic A, de Wit H. Sleep deprivation increases cigarette smoking. Pharmacol Biochem Behav. 2009 Sep; 93(3):263-9. PMID: 19133287; PMCID: PMC2706278.
      Citations: 42     Fields:    Translation:Humans
    232. White TL, Lejuez CW, de Wit H. Test-retest characteristics of the Balloon Analogue Risk Task (BART). Exp Clin Psychopharmacol. 2008 Dec; 16(6):565-70. PMID: 19086777; PMCID: PMC4244869.
      Citations: 79     Fields:    Translation:Humans
    233. Childs E, de Wit H. Hormonal, cardiovascular, and subjective responses to acute stress in smokers. Psychopharmacology (Berl). 2009 Mar; 203(1):1-12. PMID: 18936915; PMCID: PMC2727744.
      Citations: 49     Fields:    Translation:Humans
    234. de Wit H. Impulsivity as a determinant and consequence of drug use: a review of underlying processes. Addict Biol. 2009 Jan; 14(1):22-31. PMID: 18855805; PMCID: PMC3640851.
      Citations: 653     Fields:    Translation:Humans
    235. Miczek KA, de Wit H. Challenges for translational psychopharmacology research--some basic principles. Psychopharmacology (Berl). 2008 Aug; 199(3):291-301. PMID: 18523737.
      Citations: 12     Fields:    Translation:HumansAnimals
    236. Acheson A, de Wit H. Bupropion improves attention but does not affect impulsive behavior in healthy young adults. Exp Clin Psychopharmacol. 2008 Apr; 16(2):113-23. PMID: 18489015; PMCID: PMC4270475.
      Citations: 54     Fields:    Translation:Humans
    237. Phan KL, Angstadt M, Golden J, Onyewuenyi I, Popovska A, de Wit H. Cannabinoid modulation of amygdala reactivity to social signals of threat in humans. J Neurosci. 2008 Mar 05; 28(10):2313-9. PMID: 18322078; PMCID: PMC2657360.
      Citations: 120     Fields:    Translation:Humans
    238. Childs E, Hohoff C, Xu K, Badner J, de Wit H, Deckert J. Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology. 2008 Nov; 33(12):2791-800. PMID: 18305461; PMCID: PMC2745641.
      Citations: 91     Fields:    Translation:Humans
    239. Hamidovic A, Kang UJ, de Wit H. Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers. J Clin Psychopharmacol. 2008 Feb; 28(1):45-51. PMID: 18204340.
      Citations: 61     Fields:    Translation:HumansCTClinical Trials
    240. Childs E, de Wit H. Enhanced mood and psychomotor performance by a caffeine-containing energy capsule in fatigued individuals. Exp Clin Psychopharmacol. 2008 Feb; 16(1):13-21. PMID: 18266548.
      Citations: 24     Fields:    Translation:Humans
    241. White TL, Lejuez CW, de Wit H. Personality and gender differences in effects of d-amphetamine on risk taking. Exp Clin Psychopharmacol. 2007 Dec; 15(6):599-609. PMID: 18179313.
      Citations: 30     Fields:    Translation:Humans
    242. Acheson A, Richards JB, de Wit H. Effects of sleep deprivation on impulsive behaviors in men and women. Physiol Behav. 2007 Aug 15; 91(5):579-87. PMID: 17477941.
      Citations: 86     Fields:    Translation:Humans
    243. Freitag C, Hohoff C, McDonald J, Cook EH, de Wit H, Dlugos A, Deckert J. Norepinephrine transporter gene variation modulates acute response to D-amphetamine. Biol Psychiatry. 2007 Jun 01; 61(11):1296-305. PMID: 17239355.
      Citations: 25     Fields:    Translation:Humans
    244. Hariri AR, Brown SM, Williamson DE, Flory JD, de Wit H, Manuck SB. Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activity. J Neurosci. 2006 Dec 20; 26(51):13213-7. PMID: 17182771; PMCID: PMC6675016.
      Citations: 239     Fields:    Translation:Humans
    245. King A, de Wit H, Riley RC, Cao D, Niaura R, Hatsukami D. Efficacy of naltrexone in smoking cessation: a preliminary study and an examination of sex differences. Nicotine Tob Res. 2006 Oct; 8(5):671-82. PMID: 17008194.
      Citations: 43     Fields:    Translation:Humans
    246. Lott DC, Kim SJ, Cook EH, de Wit H. Serotonin transporter genotype and acute subjective response to amphetamine. Am J Addict. 2006 Sep-Oct; 15(5):327-35. PMID: 16966188.
      Citations: 19     Fields:    Translation:HumansCells
    247. White TL, Grover VK, de Wit H. Cortisol effects of D-amphetamine relate to traits of fearlessness and aggression but not anxiety in healthy humans. Pharmacol Biochem Behav. 2006 Sep; 85(1):123-31. PMID: 16934318.
      Citations: 9     Fields:    Translation:Humans
    248. de Wit H, Vicini L, Childs E, Sayla MA, Terner J. Does stress reactivity or response to amphetamine predict smoking progression in young adults? A preliminary study. Pharmacol Biochem Behav. 2007 Feb; 86(2):312-9. PMID: 16919319.
      Citations: 8     Fields:    Translation:Humans
    249. Acheson A, Farrar AM, Patak M, Hausknecht KA, Kieres AK, Choi S, de Wit H, Richards JB. Nucleus accumbens lesions decrease sensitivity to rapid changes in the delay to reinforcement. Behav Brain Res. 2006 Oct 16; 173(2):217-28. PMID: 16884790; PMCID: PMC4083481.
      Citations: 36     Fields:    Translation:Animals
    250. de Wit H, Vicini L, Haig GM, Hunt T, Feltner D. Evaluation of the abuse potential of pagoclone, a partial GABAA agonist. J Clin Psychopharmacol. 2006 Jun; 26(3):268-73. PMID: 16702891.
      Citations: 2     Fields:    Translation:Humans
    251. White TL, Lott DC, de Wit H. Personality and the subjective effects of acute amphetamine in healthy volunteers. Neuropsychopharmacology. 2006 May; 31(5):1064-74. PMID: 16237380.
      Citations: 33     Fields:    Translation:Humans
    252. Acheson A, Reynolds B, Richards JB, de Wit H. Diazepam impairs behavioral inhibition but not delay discounting or risk taking in healthy adults. Exp Clin Psychopharmacol. 2006 May; 14(2):190-8. PMID: 16756423.
      Citations: 19     Fields:    Translation:Humans
    253. Veenstra-VanderWeele J, Qaadir A, Palmer AA, Cook EH, de Wit H. Association between the casein kinase 1 epsilon gene region and subjective response to D-amphetamine. Neuropsychopharmacology. 2006 May; 31(5):1056-63. PMID: 16237383.
      Citations: 39     Fields:    Translation:HumansAnimals
    254. Acheson A, Mahler SV, Chi H, de Wit H. Differential effects of nicotine on alcohol consumption in men and women. Psychopharmacology (Berl). 2006 May; 186(1):54-63. PMID: 16565827.
      Citations: 51     Fields:    Translation:Humans
    255. Childs E, de Wit H. Subjective, behavioral, and physiological effects of acute caffeine in light, nondependent caffeine users. Psychopharmacology (Berl). 2006 May; 185(4):514-23. PMID: 16541243.
      Citations: 72     Fields:    Translation:Humans
    256. Reynolds B, Richards JB, de Wit H. Acute-alcohol effects on the Experiential Discounting Task (EDT) and a question-based measure of delay discounting. Pharmacol Biochem Behav. 2006 Feb; 83(2):194-202. PMID: 16516954.
      Citations: 92     Fields:    Translation:Humans
    257. Terner JM, de Wit H. Menstrual cycle phase and responses to drugs of abuse in humans. Drug Alcohol Depend. 2006 Sep 01; 84(1):1-13. PMID: 16413143.
      Citations: 103     Fields:    Translation:Humans
    258. Ramchandani VA, O'connor S, Neumark Y, Zimmermann US, Morzorati SL, de Wit H. The alcohol clamp: applications, challenges, and new directions--an RSA 2004 symposium summary. Alcohol Clin Exp Res. 2006 Jan; 30(1):155-64. PMID: 16433744.
      Citations: 31     Fields:    Translation:HumansAnimals
    259. King A, Munisamy G, de Wit H, Lin S. Attenuated cortisol response to alcohol in heavy social drinkers. Int J Psychophysiol. 2006 Mar; 59(3):203-9. PMID: 16359745.
      Citations: 52     Fields:    Translation:Humans
    260. Hohoff C, McDonald JM, Baune BT, Cook EH, de Wit H, Deckert J. Interindividual variation in anxiety response to amphetamine: possible role for adenosine A2A receptor gene variants. Am J Med Genet B Neuropsychiatr Genet. 2005 Nov 05; 139B(1):42-4. PMID: 16118787.
      Citations: 27     Fields:    Translation:Humans
    261. Holdstock L, Penland SN, Morrow AL, de Wit H. Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women. Psychopharmacology (Berl). 2006 Jun; 186(3):442-50. PMID: 16240164.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    262. Alsene KM, Mahler SV, de Wit H. Effects of d-amphetamine and smoking abstinence on cue-induced cigarette craving. Exp Clin Psychopharmacol. 2005 Aug; 13(3):209-18. PMID: 16173884.
      Citations: 5     Fields:    Translation:HumansAnimalsCTClinical Trials
    263. Lott DC, Kim SJ, Cook EH, de Wit H. Dopamine transporter gene associated with diminished subjective response to amphetamine. Neuropsychopharmacology. 2005 Mar; 30(3):602-9. PMID: 15602501.
      Citations: 53     Fields:    Translation:HumansCellsCTClinical Trials
    264. Mahler SV, de Wit H. Effects of haloperidol on reactions to smoking cues in humans. Behav Pharmacol. 2005 Mar; 16(2):123-6. PMID: 15767848.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    265. Young EM, Mahler S, Chi H, de Wit H. Mecamylamine and ethanol preference in healthy volunteers. Alcohol Clin Exp Res. 2005 Jan; 29(1):58-65. PMID: 15654292.
      Citations: 30     Fields:    Translation:HumansCTClinical Trials
    266. Reynolds B, Richards JB, Dassinger M, de Wit H. Therapeutic doses of diazepam do not alter impulsive behavior in humans. Pharmacol Biochem Behav. 2004 Sep; 79(1):17-24. PMID: 15388279.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    267. Zernig G, De Wit H, Telser S, Nienhusmeier M, Wakonigg G, Sturm K, Berger I, Kemmler G, Saria A. Subjective effects of slow-release bupropion versus caffeine as determined in a quasi-naturalistic setting. Pharmacology. 2004 Apr; 70(4):206-15. PMID: 15001822.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    268. Fromme K, de Wit H, Hutchison KE, Ray L, Corbin WR, Cook TA, Wall TL, Goldman D. Biological and behavioral markers of alcohol sensitivity. Alcohol Clin Exp Res. 2004 Feb; 28(2):247-56. PMID: 15112932.
      Citations: 10     Fields:    Translation:HumansAnimals
    269. Kieres AK, Hausknecht KA, Farrar AM, Acheson A, de Wit H, Richards JB. Effects of morphine and naltrexone on impulsive decision making in rats. Psychopharmacology (Berl). 2004 Apr; 173(1-2):167-74. PMID: 14752586.
      Citations: 58     Fields:    Translation:Animals
    270. de Wit H, Richards JB. Dual determinants of drug use in humans: reward and impulsivity. Nebr Symp Motiv. 2004; 50:19-55. PMID: 15160637.
      Citations: 73     Fields:    Translation:Humans
    271. Farrar AM, Kieres AK, Hausknecht KA, de Wit H, Richards JB. Effects of reinforcer magnitude on an animal model of impulsive behavior. Behav Processes. 2003 Oct 31; 64(3):261-271. PMID: 14580697.
      Citations: 11     Fields:    
    272. de Wit H, Nikolayev L, Young E, Söderpalm AH. Effects of acute social stress on alcohol consumption in healthy subjects. Alcohol Clin Exp Res. 2003 Aug; 27(8):1270-7. PMID: 12966321.
      Citations: 50     Fields:    Translation:HumansCTClinical Trials
    273. Nikolayev L, de Wit H, Söderpalm A. Effects of stress on responses to methamphetamine in humans. Psychopharmacology (Berl). 2003 Nov; 170(2):188-99. PMID: 12845405.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    274. Alsene K, Sand P, de Wit H, Deckert J. Association between A2a receptor gene polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology. 2003 Sep; 28(9):1694-702. PMID: 12825092.
      Citations: 108     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    275. Chi H, de Wit H. Mecamylamine attenuates the subjective stimulant-like effects of alcohol in social drinkers. Alcohol Clin Exp Res. 2003 May; 27(5):780-6. PMID: 12766622.
      Citations: 50     Fields:    Translation:HumansCTClinical Trials
    276. McDonald J, Schleifer L, Richards JB, de Wit H. Effects of THC on behavioral measures of impulsivity in humans. Neuropsychopharmacology. 2003 Jul; 28(7):1356-65. PMID: 12784123.
      Citations: 164     Fields:    Translation:HumansCTClinical Trials
    277. Alsene KM, Li Y, Chaverneff F, de Wit H. Role of abstinence and visual cues on food and smoking craving. Behav Pharmacol. 2003 Mar; 14(2):145-51. PMID: 12658075.
      Citations: 7     Fields:    Translation:Humans
    278. Crean J, Richards JB, de Wit H. Effect of tryptophan depletion on impulsive behavior in men with or without a family history of alcoholism. Behav Brain Res. 2002 Nov 15; 136(2):349-57. PMID: 12429396.
      Citations: 63     Fields:    Translation:HumansCTClinical Trials
    279. de Wit H, Enggasser JL, Richards JB. Acute administration of d-amphetamine decreases impulsivity in healthy volunteers. Neuropsychopharmacology. 2002 Nov; 27(5):813-25. PMID: 12431855.
      Citations: 206     Fields:    Translation:HumansCTClinical Trials
    280. White TL, Justice AJ, de Wit H. Differential subjective effects of D-amphetamine by gender, hormone levels and menstrual cycle phase. Pharmacol Biochem Behav. 2002 Nov; 73(4):729-41. PMID: 12213517.
      Citations: 134     Fields:    Translation:HumansCTClinical Trials
    281. Shaham Y, Shalev U, Lu L, de Wit H, Stewart J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl). 2003 Jul; 168(1-2):3-20. PMID: 12402102.
      Citations: 796     Fields:    Translation:HumansAnimalsPHPublic Health
    282. Reynolds B, de Wit H, Richards J. Delay of gratification and delay discounting in rats. Behav Processes. 2002 Sep 30; 59(3):157. PMID: 12270518.
      Citations: 28     Fields:    
    283. Wachtel SR, Ortengren A, de Wit H. The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers. Drug Alcohol Depend. 2002 Sep 01; 68(1):23-33. PMID: 12167550.
      Citations: 32     Fields:    Translation:HumansCTClinical Trials
    284. de Wit H, Söderpalm AH. Effects of stress and alcohol on subjective state in humans. Alcohol Clin Exp Res. 2002 Jun; 26(6):818-26. PMID: 12068250.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    285. King AC, Houle T, de Wit H, Holdstock L, Schuster A. Biphasic alcohol response differs in heavy versus light drinkers. Alcohol Clin Exp Res. 2002 Jun; 26(6):827-35. PMID: 12068251.
      Citations: 136     Fields:    Translation:HumansCTClinical Trials
    286. Wachtel SR, ElSohly MA, Ross SA, Ambre J, de Wit H. Comparison of the subjective effects of Delta(9)-tetrahydrocannabinol and marijuana in humans. Psychopharmacology (Berl). 2002 Jun; 161(4):331-9. PMID: 12073159.
      Citations: 101     Fields:    Translation:HumansAnimalsCTClinical Trials
    287. Cousins MS, Roberts DC, de Wit H. GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings. Drug Alcohol Depend. 2002 Feb 01; 65(3):209-20. PMID: 11841892.
      Citations: 80     Fields:    Translation:HumansAnimals
    288. Schleifer LA, Justice AJ, de Wit H. Lack of effects of acute estradiol on mood in postmenopausal women. Pharmacol Biochem Behav. 2002 Jan-Feb; 71(1-2):71-7. PMID: 11812509.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    289. Uftring SJ, Wachtel SR, Chu D, McCandless C, Levin DN, de Wit H. An fMRI study of the effect of amphetamine on brain activity. Neuropsychopharmacology. 2001 Dec; 25(6):925-35. PMID: 11750185.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    290. Enggasser JL, de Wit H. Haloperidol reduces stimulant and reinforcing effects of ethanol in social drinkers. Alcohol Clin Exp Res. 2001 Oct; 25(10):1448-56. PMID: 11696664.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    291. de Wit H, Schmitt L, Purdy R, Hauger R. Effects of acute progesterone administration in healthy postmenopausal women and normally-cycling women. Psychoneuroendocrinology. 2001 Oct; 26(7):697-710. PMID: 11500251.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    292. Cousins MS, Stamat HM, de Wit H. Acute doses of d-amphetamine and bupropion increase cigarette smoking. Psychopharmacology (Berl). 2001 Sep; 157(3):243-53. PMID: 11605079.
      Citations: 49     Fields:    Translation:HumansCTClinical Trials
    293. Wachtel SR, de Wit H. Lack of effect of intravenous hydrocortisone on mood in humans: a preliminary study. Behav Pharmacol. 2001 Sep; 12(5):373-6. PMID: 11710752.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    294. Schuster A, de Wit H, Söderpalm AH. Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. Pharmacol Biochem Behav. 2001 Jul-Aug; 69(3-4):343-50. PMID: 11509190.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    295. Cousins MS, Stamat HM, de Wit H. Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking. Nicotine Tob Res. 2001 May; 3(2):123-9. PMID: 11403726.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    296. Holdstock L, de Wit H. Individual differences in responses to ethanol and d-amphetamine: a within-subject study. Alcohol Clin Exp Res. 2001 Apr; 25(4):540-8. PMID: 11329494.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    297. Wachtel SR, Charnot A, de Wit H. Acute hydrocortisone administration does not affect subjective responses to d-amphetamine in humans. Psychopharmacology (Berl). 2001 Jan; 153(3):380-8. PMID: 11271411.
      Citations: 5     Fields:    Translation:Humans
    298. de Wit H. Laboratory-based assessment of alcohol craving in social drinkers. Addiction. 2000 Aug; 95 Suppl 2:S165-9. PMID: 11002911.
      Citations: 25     Fields:    Translation:Humans
    299. de Wit H, Crean J, Richards JB. Effects of d-amphetamine and ethanol on a measure of behavioral inhibition in humans. Behav Neurosci. 2000 Aug; 114(4):830-7. PMID: 10959541.
      Citations: 115     Fields:    Translation:HumansCTClinical Trials
    300. Feola TW, de Wit H, Richards JB. Effects of d-amphetamine and alcohol on a measure of behavioral inhibition in rats. Behav Neurosci. 2000 Aug; 114(4):838-848. PMID: 10959542.
      Citations: 49     Fields:    Translation:Animals
    301. Holdstock L, de Wit H. Effects of ethanol at four phases of the menstrual cycle. Psychopharmacology (Berl). 2000 Jul; 150(4):374-82. PMID: 10958078.
      Citations: 31     Fields:    Translation:Humans
    302. Justice AJ, De Wit H. Acute effects of d-amphetamine during the early and late follicular phases of the menstrual cycle in women. Pharmacol Biochem Behav. 2000 Jul; 66(3):509-15. PMID: 10899363.
      Citations: 39     Fields:    Translation:HumansCTClinical Trials
    303. Holdstock L, King AC, de Wit H. Subjective and objective responses to ethanol in moderate/heavy and light social drinkers. Alcohol Clin Exp Res. 2000 Jun; 24(6):789-94. PMID: 10888066.
      Citations: 90     Fields:    Translation:Humans
    304. Wachtel SR, de Wit H. Naltrexone does not block the subjective effects of oral Delta(9)-tetrahydrocannabinol in humans. Drug Alcohol Depend. 2000 Jun 01; 59(3):251-60. PMID: 10812285.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    305. Crean JP, de Wit H, Richards JB. Reward discounting as a measure of impulsive behavior in a psychiatric outpatient population. Exp Clin Psychopharmacol. 2000 May; 8(2):155-62. PMID: 10843297.
      Citations: 54     Fields:    Translation:HumansCTClinical Trials
    306. Justice AJ, de Wit H. Acute effects of estradiol pretreatment on the response to d-amphetamine in women. Neuroendocrinology. 2000 Jan; 71(1):51-9. PMID: 10644899.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    307. Kirk JM, de Wit H. Individual differences in the priming effect of ethanol in social drinkers. J Stud Alcohol. 2000 Jan; 61(1):64-71. PMID: 10627098.
      Citations: 22     Fields:    Translation:Humans
    308. Rukstalis M, de Wit H. Effects of triazolam at three phases of the menstrual cycle. J Clin Psychopharmacol. 1999 Oct; 19(5):450-8. PMID: 10505587.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    309. de Wit H, Svenson J, York A. Non-specific effect of naltrexone on ethanol consumption in social drinkers. Psychopharmacology (Berl). 1999 Sep 01; 146(1):33-41. PMID: 10485962.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    310. Justice AJ, de Wit H. Acute effects of d-amphetamine during the follicular and luteal phases of the menstrual cycle in women. Psychopharmacology (Berl). 1999 Jul; 145(1):67-75. PMID: 10445374.
      Citations: 93     Fields:    Translation:Humans
    311. Wachtel SR, de Wit H. Subjective and behavioral effects of repeated d-amphetamine in humans. Behav Pharmacol. 1999 May; 10(3):271-81. PMID: 10780242.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    312. Holdstock L, de Wit H. Individual differences in subjective responses to ethanol and triazolam. Behav Pharmacol. 1999 May; 10(3):283-95. PMID: 10780243.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    313. Kirk JM, de Wit H. Responses to oral delta9-tetrahydrocannabinol in frequent and infrequent marijuana users. Pharmacol Biochem Behav. 1999 May; 63(1):137-42. PMID: 10340534.
      Citations: 36     Fields:    Translation:Humans
    314. Holdstock L, de Wit H. Ethanol impairs saccadic and smooth pursuit eye movements without producing self-reports of sedation. Alcohol Clin Exp Res. 1999 Apr; 23(4):664-72. PMID: 10235302.
      Citations: 10     Fields:    Translation:Humans
    315. Richards JB, Zhang L, Mitchell SH, de Wit H. Delay or probability discounting in a model of impulsive behavior: effect of alcohol. J Exp Anal Behav. 1999 Mar; 71(2):121-43. PMID: 10220927; PMCID: PMC1284697.
      Citations: 275     Fields:    Translation:HumansCTClinical Trials
    316. Holdstock L, de Wit H. Individual differences in the biphasic effects of ethanol. Alcohol Clin Exp Res. 1998 Dec; 22(9):1903-11. PMID: 9884132.
      Citations: 44     Fields:    Translation:HumansCTClinical Trials
    317. de Wit H. Individual differences in acute effects of drugs in humans: their relevance to risk for abuse. NIDA Res Monogr. 1998 Mar; 169:176-87. PMID: 9686416.
      Citations: 11     Fields:    Translation:HumansAnimals
    318. Kirk JM, Doty P, De Wit H. Effects of expectancies on subjective responses to oral delta9-tetrahydrocannabinol. Pharmacol Biochem Behav. 1998 Feb; 59(2):287-93. PMID: 9476972.
      Citations: 36     Fields:    Translation:HumansCTClinical Trials
    319. Cooper M, Metz J, de Wit H, Cook E, Lorenz J, Brown T. Interclass drug effects and changes in regional brain glucose metabolism. Psychopharmacol Bull. 1998; 34(2):229-32. PMID: 9641006.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    320. Doty P, Kirk JM, Cramblett MJ, de Wit H. Behavioral responses to ethanol in light and moderate social drinkers following naltrexone pretreatment. Drug Alcohol Depend. 1997 Aug 25; 47(2):109-16. PMID: 9298332.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    321. Richards JB, Mitchell SH, de Wit H, Seiden LS. Determination of discount functions in rats with an adjusting-amount procedure. J Exp Anal Behav. 1997 May; 67(3):353-66. PMID: 9163939; PMCID: PMC1284611.
      Citations: 164     Fields:    Translation:Animals
    322. de Wit H, Clark M, Brauer LH. Effects of d-amphetamine in grouped versus isolated humans. Pharmacol Biochem Behav. 1997 May-Jun; 57(1-2):333-40. PMID: 9164591.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    323. de Wit H, Rukstalis M. Acute effects of triazolam in women: relationships with progesterone, estradiol and allopregnanolone. Psychopharmacology (Berl). 1997 Mar; 130(1):69-78. PMID: 9089849.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    324. Zacny JP, Mitchell SH, Cramblett MJ, de Wit H. The effects of ethanol on the relative preference for cigarettes. Behav Pharmacol. 1997 Feb; 8(1):75-81. PMID: 9833003.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    325. Mitchell SH, Laurent CL, de Wit H. Interaction of expectancy and the pharmacological effects of d-amphetamine: subjective effects and self-administration. Psychopharmacology (Berl). 1996 Jun; 125(4):371-8. PMID: 8826542.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    326. Brauer LH, Johanson CE, Schuster CR, Rothman RB, de Wit H. Evaluation of phentermine and fenfluramine, alone and in combination, in normal, healthy volunteers. Neuropsychopharmacology. 1996 Apr; 14(4):233-41. PMID: 8924191.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    327. Brauer LH, Ambre J, De Wit H. Acute tolerance to subjective but not cardiovascular effects of d-amphetamine in normal, healthy men. J Clin Psychopharmacol. 1996 Feb; 16(1):72-6. PMID: 8834422.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    328. Brauer LH, de Wit H. Subjective responses to d-amphetamine alone and after pimozide pretreatment in normal, healthy volunteers. Biol Psychiatry. 1996 Jan 01; 39(1):26-32. PMID: 8719123.
      Citations: 34     Fields:    Translation:HumansCTClinical Trials
    329. Brauer LH, Rukstalis MR, de Wit H. Acute subjective responses to paroxetine in normal volunteers. Drug Alcohol Depend. 1995 Oct; 39(3):223-30. PMID: 8556971.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    330. Mitchell SH, de Wit H, Zacny JP. Caffeine withdrawal symptoms and self-administration following caffeine deprivation. Pharmacol Biochem Behav. 1995 Aug; 51(4):941-5. PMID: 7675881.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    331. Mitchell SH, de Wit H, Zacny JP. Effects of varying ethanol dose on cigarette consumption in healthy normal volunteers. Behav Pharmacol. 1995 Jun; 6(4):359-365. PMID: 11224344.
      Citations: 38     Fields:    
    332. Doty P, de Wit H. Effects of naltrexone pretreatment on the subjective and performance effects of ethanol in social drinkers. Behav Pharmacol. 1995 Jun; 6(4):386-394. PMID: 11224347.
      Citations: 5     Fields:    
    333. Doty P, de Wit H. Effect of setting on the reinforcing and subjective effects of ethanol in social drinkers. Psychopharmacology (Berl). 1995 Mar; 118(1):19-27. PMID: 7597118.
      Citations: 49     Fields:    Translation:HumansCTClinical Trials
    334. de Wit H, Bodker B. Personality and drug preferences in normal volunteers. Int J Addict. 1994 Oct; 29(12):1617-30. PMID: 7836023.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    335. de Wit H, Doty P. Preference for ethanol and diazepam in light and moderate social drinkers: a within-subjects study. Psychopharmacology (Berl). 1994 Aug; 115(4):529-38. PMID: 7871098.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    336. Doty P, Zacny JP, de Wit H. Effects of ondansetron pretreatment on acute responses to ethanol in social drinkers. Behav Pharmacol. 1994 Aug; 5(4 And 5):461-469. PMID: 11224298.
      Citations: 7     Fields:    
    337. Brauer LH, Buican B, de Wit H. Effects of caffeine deprivation on taste and mood. Behav Pharmacol. 1994 Apr; 5(2):111-118. PMID: 11224258.
      Citations: 2     Fields:    
    338. Mitchell SH, de Wit H, Zacny JP. Effects of varying the "openness" of an economy on responding for cigarettes. Behav Pharmacol. 1994 Apr; 5(2):159-166. PMID: 11224264.
      Citations: 7     Fields:    
    339. Chutuape MA, de Wit H. Relationship between subjective effects and drug preferences: ethanol and diazepam. Drug Alcohol Depend. 1994 Feb; 34(3):243-51. PMID: 8033763.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    340. Dohrn CS, Lichtor JL, Coalson DW, Uitvlugt A, de Wit H, Zacny JP. Reinforcing effects of extended inhalation of nitrous oxide in humans. Drug Alcohol Depend. 1993 Feb; 31(3):265-80. PMID: 8462415.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    341. de Wit H, Dudish S, Ambre J. Subjective and behavioral effects of diazepam depend on its rate of onset. Psychopharmacology (Berl). 1993; 112(2-3):324-30. PMID: 7871037.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    342. Cole-Harding S, de Wit H. Self-administration of pentobarbital in light and moderate alcohol drinkers. Pharmacol Biochem Behav. 1992 Oct; 43(2):563-9. PMID: 1438493.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    343. Zacny JP, Lichtor JL, de Wit H. Subjective, behavioral, and physiologic responses to intravenous dezocine in healthy volunteers. Anesth Analg. 1992 Apr; 74(4):523-30. PMID: 1348168.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    344. Dohrn CS, Lichtor JL, Finn RS, Uitvlugt A, Coalson DW, Rupani G, de Wit H, Zacny JP. Subjective and psychomotor effects of nitrous oxide in healthy volunteers. Behav Pharmacol. 1992 Feb; 3(1):19-30. PMID: 11224098.
      Citations: 6     Fields:    
    345. de Wit H, Metz J, Cooper M. Studying psychoactive drugs with positron emission tomography: relationships between mood and metabolic rate. NIDA Res Monogr. 1992; 124:117-34. PMID: 1470208.
      Citations:    Fields:    Translation:Humans
    346. Zacny JP, Lichtor JL, Zaragoza JG, de Wit H. Effects of fasting on responses to intravenous fentanyl in healthy volunteers. J Subst Abuse. 1992; 4(2):197-207. PMID: 1504643.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    347. Zacny JP, de Wit H. The effects of a restricted feeding regimen on cigarette smoking in humans. Addict Behav. 1992; 17(2):149-57. PMID: 1585842.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    348. Zacny JP, Bodker BK, de Wit H. Effects of setting on the subjective and behavioral effects of d-amphetamine in humans. Addict Behav. 1992; 17(1):27-33. PMID: 1595423.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    349. Zacny JP, Lichtor JL, Zaragoza JG, de Wit H. Subjective and behavioral responses to intravenous fentanyl in healthy volunteers. Psychopharmacology (Berl). 1992; 107(2-3):319-26. PMID: 1615132.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    350. De Wit H. Preference procedures for testing the abuse liability of drugs in humans. Br J Addict. 1991 Dec; 86(12):1579-86. PMID: 1786490.
      Citations: 4     Fields:    Translation:Humans
    351. de Wit H. Diazepam preference in males with and without an alcoholic first-degree relative. Alcohol Clin Exp Res. 1991 Aug; 15(4):593-600. PMID: 1928632.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    352. de Wit H, Metz J, Wagner N, Cooper M. Effects of diazepam on cerebral metabolism and mood in normal volunteers. Neuropsychopharmacology. 1991 Aug; 5(1):33-41. PMID: 1930609.
      Citations: 1     Fields:    Translation:Humans
    353. Zacny JP, de Wit H. Effects of food deprivation on subjective effects and self-administration of marijuana in humans. Psychol Rep. 1991 Jun; 68(3 Pt 2):1263-74. PMID: 1924625.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    354. de Wit H, Griffiths RR. Testing the abuse liability of anxiolytic and hypnotic drugs in humans. Drug Alcohol Depend. 1991 Jun; 28(1):83-111. PMID: 1679388.
      Citations: 44     Fields:    Translation:Humans
    355. de Wit H, Metz J, Wagner N, Cooper M. Behavioral and subjective effects of ethanol: relationship to cerebral metabolism using PET. Alcohol Clin Exp Res. 1990 Jun; 14(3):482-9. PMID: 2198826.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    356. McCracken SG, de Wit H, Uhlenhuth EH, Johanson CE. Preference for diazepam in anxious adults. J Clin Psychopharmacol. 1990 Jun; 10(3):190-6. PMID: 2198297.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    357. Zacny JP, de Wit H. Effects of a 24-hour fast on cigarette smoking in humans. Br J Addict. 1990 Apr; 85(4):555-60. PMID: 2346795.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    358. de Wit H, McCracken SG. Ethanol self-administration in males with and without an alcoholic first-degree relative. Alcohol Clin Exp Res. 1990 Feb; 14(1):63-70. PMID: 2178475.
      Citations: 28     Fields:    Translation:Humans
    359. de Wit H, Metz J, Cooper M. Effects of ethanol, diazepam and amphetamines on cerebral metabolic rate: PET studies using FDG. NIDA Res Monogr. 1990; 105:61-7. PMID: 1876142.
      Citations:    Fields:    Translation:Humans
    360. Zacny JP, de Wit H. Effects of food deprivation on subjective responses to d-amphetamine in humans. Pharmacol Biochem Behav. 1989 Dec; 34(4):791-5. PMID: 2623032.
      Citations: 2     Fields:    Translation:Humans
    361. de Wit H, Metz J, Cooper M. The effects of 0.8 g.kg ethanol on cerebral metabolism and mood in normal volunteers. NIDA Res Monogr. 1989; 95:450. PMID: 2641027.
      Citations:    Fields:    Translation:Humans
    362. de Wit H, Pierri J, Johanson CE. Assessing pentobarbital preference in normal volunteers using a cumulative dosing procedure. Psychopharmacology (Berl). 1989; 99(3):416-21. PMID: 2594908.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    363. Zacny JP, de Wit H. Effects of food deprivation on responses to marijuana in humans. Behav Pharmacol. 1989; 1(2):177-185. PMID: 11175401.
      Citations: 1     Fields:    
    364. de Wit H, McCracken SM, Uhlenhuth EH, Johanson CE. Diazepam preference in subjects seeking treatment for anxiety. NIDA Res Monogr. 1987; 76:248-54. PMID: 3125453.
      Citations:    Fields:    Translation:Humans
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