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Harriet De Wit

TitleProfessor
InstitutionUniversity of Chicago
DepartmentPsychiatry and Behavioral Neuroscience-Research
AddressChicago IL 60637
Email
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    Collapse Overview 
    Collapse overview
    The de Wit laboratory investigates the subjective, behavioral and physiological effects of drugs of abuse in healthy human volunteers. Some studies are designed to identify individual differences and risk factors for excessive use, and others to determine the effects of drugs on mood, psychomotor and cognitive performance, and brain activity. Another major interest is the study of conditioned drug effects, or cues, that influence future drug use.
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    Collapse Biography 
    Collapse education and training
    University of Calgary, Calgary CanadaBA1969Psychology
    Concordia University, Montreal CanadaPhD02/1981Experimental Psychology
    Collapse awards and honors
    1999Solvay Award for Outstanding Basic Psychopharmacological Research in Affective Disorders , American Psychological Association
    2009Marian W. Fischman Memorial Lectureship Award, College of Problems on Drug Dependence
    2016Distinguished Lecturer, Elizabeth Fitzgerald Sporar Endowment Distinguished Initiatives in Addiction, University of Texas
    2019Distinguished Achievement Award, European Behavioural Pharmacology Society
    2020Lifetime Achievement Award, Research Society on Alcoholism
    2020John F. Lemieux Medal for Distinguished Alumni, Concordia University, Montreal

    Collapse Research 
    Collapse research activities and funding
    T32DA043469     (HEDEKER, DONALD ;ZHUANG, XIAOXI)Jul 1, 2017 - Jun 30, 2027
    NIH
    Integrative Training in the Neurobiology of Addictive Behaviors
    Role: Principal Investigator

    R21DA037642     (DE WIT, HARRIET)Apr 1, 2015 - Mar 31, 2018
    NIH
    Inhibitory Control and Drug Reward in Humans
    Role: Principal Investigator

    R21DA031796     (DE WIT, HARRIET)Feb 15, 2012 - Jan 31, 2016
    NIH
    Memory effects of stimulant drugs in humans
    Role: Principal Investigator

    R01DA032015     (DE WIT, HARRIET)Jul 15, 2011 - Apr 30, 2018
    NIH
    The genetic basis of impulsive behavior in humans
    Role: Principal Investigator

    R21DA026570     (DE WIT, HARRIET)Sep 30, 2009 - Aug 31, 2013
    NIH
    Is Ecstasy an Empathogen? Effects of MDMA on Social and Emotional Processing
    Role: Principal Investigator

    R21DA020773     (DE WIT, HARRIET)Jun 1, 2007 - Feb 28, 2009
    NIH
    Craving During Smoking Abstinence: Does it Abate or Incubate?
    Role: Principal Investigator

    R03AA013729     (DE WIT, HARRIET)Sep 15, 2002 - Aug 31, 2005
    NIH
    Nicotinic Involvement &Consumption of Alcohol in Humans
    Role: Principal Investigator

    R03DA012143     (DE WIT, HARRIET)Sep 30, 1999 - Sep 29, 2001
    NIH
    BLOCKADE OF METHAMPHETAMINE SUBJECTIVE EFFECTS IN HUMANS
    Role: Principal Investigator

    R01DA009133     (DE WIT, HARRIET)Apr 20, 1996 - Mar 31, 2012
    NIH
    Drug Abuse and Impulsivity: Human Laboratory Models
    Role: Principal Investigator

    R01DA006176     (DE WIT, HARRIET)Mar 1, 1990 - Feb 29, 1996
    NIH
    DRUGS OF ABUSE ON REGIONAL CEREBRAL METABOLISM AND MOOD
    Role: Principal Investigator

    R01DA005704     (ZACNY, JAMES P.)Sep 1, 1989 - Jun 30, 1996
    NIH
    BEHAVIORAL ECONOMICS OF DRUG CHOICE
    Role: Co-Principal Investigator

    R01DA003517     (DE WIT, HARRIET)May 1, 1984 - Jul 31, 2001
    NIH
    PHARMACOLOGIC STUDIES OF MARIJUANA &ALPHA THC IN HUMAN
    Role: Principal Investigator

    R01DA002812     (DE WIT, HARRIET)Jan 1, 1981 - Jan 31, 2025
    NIH
    Determinants of Drug Preference in Humans
    Role Description: The goal of the study is to identify individual differences in brain reward processes related to stimulant-induced euphoria.
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Murray CH, Frohlich J, Haggarty CJ, Tare I, Lee R, de Wit H. Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine. Neuropsychopharmacology. 2024 Jan 29. PMID: 38287172.
      Citations:    Fields:    
    2. Bershad AK, Hsu DT, de Wit H. MDMA enhances positive affective responses to social feedback. J Psychopharmacol. 2024 Jan 27; 2698811231224153. PMID: 38279662.
      Citations:    Fields:    
    3. Murphy R, Muthukumaraswamy S, de Wit H. Microdosing psychedelics: Current evidence from controlled studies. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Jan 25. PMID: 38280630.
      Citations:    Fields:    
    4. Aaronson AL, Smith B, Krese K, Barnhart M, Adamson M, de Wit H, Philip NS, Brenner LA, Bender-Pape T, Herrold AA. Impulsivity and Psychiatric Diagnoses as Mediators of Suicidal Ideation and Suicide Attempts Among Veterans With Traumatic Brain Injury. J Neuropsychiatry Clin Neurosci. 2024 Jan 09; appineuropsych20230044. PMID: 38192217.
      Citations:    Fields:    
    5. Haggarty CJ, Glazer JE, Nusslock R, Lee R, de Wit H. Lack of effect of methamphetamine on reward-related brain activity in healthy adults. Psychopharmacology (Berl). 2024 Jan; 241(1):181-193. PMID: 38141075.
      Citations:    Fields:    Translation:Humans
    6. Doss MK, Samaha J, Barrett FS, Griffiths RR, de Wit H, Gallo DA, Koen JD. Unique effects of sedatives, dissociatives, psychedelics, stimulants, and cannabinoids on episodic memory: A review and reanalysis of acute drug effects on recollection, familiarity, and metamemory. Psychol Rev. 2023 Dec 14. PMID: 38095937.
      Citations:    Fields:    
    7. Molla H, Lee R, Tare I, de Wit H. Greater subjective effects of a low dose of LSD in participants with depressed mood. Neuropsychopharmacology. 2023 Dec 02. PMID: 38042914.
      Citations:    Fields:    
    8. Molla H, Lee R, Lyubomirsky S, de Wit H. Drug-induced social connection: both MDMA and methamphetamine increase feelings of connectedness during controlled dyadic conversations. Sci Rep. 2023 09 22; 13(1):15846. PMID: 37740024; PMCID: PMC10516994.
      Citations: 2     Fields:    Translation:Humans
    9. Bershad AK, de Wit H. Social Psychopharmacology: Novel Approaches to Treat Deficits in Social Motivation in Schizophrenia. Schizophr Bull. 2023 09 07; 49(5):1161-1173. PMID: 37358825; PMCID: PMC10483474.
      Citations:    Fields:    Translation:Humans
    10. Han J, Keedy S, de Wit H. Stimulant-like subjective effects of alcohol are not related to resting-state connectivity in healthy men. Cereb Cortex. 2023 08 08; 33(16):9478-9488. PMID: 37339883; PMCID: PMC10656944.
      Citations:    Fields:    Translation:Humans
    11. Crane NA, Molla H, de Wit H. Methamphetamine alters nucleus accumbens neural activation to monetary loss in healthy young adults. Psychopharmacology (Berl). 2023 Sep; 240(9):1891-1900. PMID: 37530883; PMCID: PMC10572040.
      Citations:    Fields:    Translation:Humans
    12. Molla H, Keedy S, DeBrosse J, de Wit H. Methamphetamine enhances neural activation during anticipation of loss in the monetary incentive delay task. Cereb Cortex Commun. 2023; 4(3):tgad014. PMID: 37565072; PMCID: PMC10412021.
      Citations:    
    13. Doss MK, de Wit H, Gallo DA. The acute effects of psychoactive drugs on emotional episodic memory encoding, consolidation, and retrieval: A comprehensive review. Neurosci Biobehav Rev. 2023 07; 150:105188. PMID: 37085021; PMCID: PMC10247427.
      Citations:    Fields:    Translation:Humans
    14. Pabon E, de Wit H. Impaired inhibition after delta-9-tetrahydrocannabinol in women not related to circulating estradiol levels. Pharmacol Biochem Behav. 2023 04; 225:173547. PMID: 37004978.
      Citations:    Fields:    Translation:HumansAnimalsCTClinical Trials
    15. de Wit H. Progress and Puzzles in Psychedelic Therapy. Biol Psychiatry. 2023 02 01; 93(3):210. PMID: 36567083.
      Citations:    Fields:    
    16. Krishnan S, Bevins RA, de Wit H. Place conditioning in humans: opportunities for translational research. Psychopharmacology (Berl). 2023 Nov; 240(11):2221-2230. PMID: 36656336.
      Citations:    Fields:    
    17. Glazer J, Murray CH, Nusslock R, Lee R, de Wit H. Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity. Neuropsychopharmacology. 2023 01; 48(2):418-426. PMID: 36284231; PMCID: PMC9751270.
      Citations: 6     Fields:    Translation:Humans
    18. Nunez C, Hoots JK, Schepers ST, Bower M, de Wit H, Wardle MC. Pharmacological investigations of effort-based decision-making in humans: Naltrexone and nicotine. PLoS One. 2022; 17(10):e0275027. PMID: 36197897; PMCID: PMC9534411.
      Citations:    Fields:    Translation:Humans
    19. Pabon E, Greenlund IM, Carter JR, de Wit H. Effects of alcohol on sleep and nocturnal heart rate: Relationships to intoxication and morning-after effects. Alcohol Clin Exp Res. 2022 10; 46(10):1875-1887. PMID: 35953878; PMCID: PMC9826048.
      Citations: 1     Fields:    Translation:Humans
    20. de Wit H, D'Souza DC. Psychedelics: Old trips, new destinations in psychopharmacology research. Psychopharmacology (Berl). 2022 Jun; 239(6):1643-1645. PMID: 35460341.
      Citations:    
    21. de Wit H, D'Souza DC. Correction to: Psychedelics: Old trips, new destinations in psychopharmacology research. Psychopharmacology (Berl). 2022 Jun; 239(6):1647. PMID: 35543715.
      Citations:    Fields:    
    22. Murray CH, Glazer JE, Lee R, Nusslock R, de Wit H. ?9-THC reduces reward-related brain activity in healthy adults. Psychopharmacology (Berl). 2022 Sep; 239(9):2829-2840. PMID: 35612654; PMCID: PMC10560585.
      Citations: 2     Fields:    Translation:Humans
    23. Pabon E, de Wit H. Effects of Oral Delta-9-Tetrahydrocannabinol in Women During the Follicular Phase of the Menstrual Cycle. Cannabis Cannabinoid Res. 2023 Dec; 8(6):1117-1125. PMID: 35593915; PMCID: PMC10714110.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    24. King A, Vena A, de Wit H, Grant JE, Cao D. Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily: A Randomized Clinical Trial. JAMA Netw Open. 2022 Mar 01; 5(3):e220951. PMID: 35244704; PMCID: PMC8897753.
      Citations: 3     Fields:    Translation:Humans
    25. Murray CH, Huang Z, Lee R, de Wit H. Adolescents are more sensitive than adults to acute behavioral and cognitive effects of THC. Neuropsychopharmacology. 2022 06; 47(7):1331-1338. PMID: 35110688; PMCID: PMC9117219.
      Citations: 8     Fields:    Translation:HumansAnimals
    26. Wardle MC, Pabon E, Webber HE, de Wit H. Delta-9-tetrahydrocannabinol reduces willingness to exert effort in women. Psychopharmacology (Berl). 2022 May; 239(5):1487-1497. PMID: 35102424; PMCID: PMC8803458.
      Citations: 2     Fields:    Translation:HumansAnimals
    27. de Wit H, Molla HM, Bershad A, Bremmer M, Lee R. Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study. Addict Biol. 2022 03; 27(2):e13143. PMID: 35106880.
      Citations: 11     Fields:    Translation:Humans
    28. Malina M, Keedy S, Weafer J, Van Hedger K, de Wit H. Effects of Methamphetamine on Within- and Between-Network Connectivity in Healthy Adults. Cereb Cortex Commun. 2021; 2(4):tgab063. PMID: 34859242; PMCID: PMC8633740.
      Citations: 1     
    29. Regan A, Margolis S, de Wit H, Lyubomirsky S. Does ±3,4-methylenedioxymethamphetamine (ecstasy) induce subjective feelings of social connection in humans? A multilevel meta-analysis. PLoS One. 2021; 16(10):e0258849. PMID: 34695117; PMCID: PMC8544845.
      Citations: 7     Fields:    Translation:Humans
    30. Pabon E, Rockwood F, Norman GJ, de Wit H. Acute effects of oral delta-9-tetrahydrocannabinol (THC) on autonomic cardiac activity and their relation to subjective and anxiogenic effects. Psychophysiology. 2022 02; 59(2):e13955. PMID: 34665890; PMCID: PMC8724445.
      Citations: 3     Fields:    Translation:Humans
    31. Murray CH, Tare I, Perry CM, Malina M, Lee R, de Wit H. Low doses of LSD reduce broadband oscillatory power and modulate event-related potentials in healthy adults. Psychopharmacology (Berl). 2022 Jun; 239(6):1735-1747. PMID: 34613430.
      Citations: 13     Fields:    Translation:Humans
    32. Di Ciano P, de Wit H, Mansouri E, Houle S, Boileau I, Le Foll B. The influence of conditioned stimuli on [11C]-(+)-PHNO PET binding in tobacco smokers after a one week abstinence. Sci Rep. 2021 06 03; 11(1):11667. PMID: 34083612; PMCID: PMC8175373.
      Citations: 1     Fields:    Translation:Humans
    33. de Wit H, Bershad AK, Grob C. Challenges in translational research: MDMA in the laboratory versus therapeutic settings. J Psychopharmacol. 2022 Mar; 36(3):252-257. PMID: 33944625.
      Citations: 5     Fields:    Translation:Humans
    34. Weafer J, Gorka SM, Dzemidzic M, Kareken DA, Phan KL, de Wit H. Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol. Neuropsychopharmacology. 2021 07; 46(8):1442-1450. PMID: 33947965; PMCID: PMC8208996.
      Citations: 5     Fields:    Translation:Humans
    35. de Wit H, Bershad AK, Hutchison W, Bremmer M. Can MDMA Change Sociopolitical Values? Insights From a Research Participant. Biol Psychiatry. 2021 06 01; 89(11):e61-e62. PMID: 33814127.
      Citations: 3     Fields:    Translation:Humans
    36. Van Hedger K, Bershad AK, Madray R, de Wit H, Mayo LM. Effects of Acute Drug Administration on Emotion: A Review of Pharmacological MRI Studies. Curr Addict Rep. 2021 Jun; 8(2):181-193. PMID: 34631363; PMCID: PMC8494189.
      Citations: 2     
    37. Murray CH, Li J, Weafer J, de Wit H. Subjective responses predict d-amphetamine choice in healthy volunteers. Pharmacol Biochem Behav. 2021 05; 204:173158. PMID: 33675838; PMCID: PMC8018542.
      Citations: 1     Fields:    Translation:Humans
    38. Han J, Keedy S, Murray CH, Foxley S, de Wit H. Acute effects of alcohol on resting-state functional connectivity in healthy young men. Addict Behav. 2021 04; 115:106786. PMID: 33421747; PMCID: PMC8693384.
      Citations: 9     Fields:    Translation:Humans
    39. Pabon E, Crane NA, Radoman M, Weafer J, Langenecker SA, Phan KL, de Wit H. Neural activation during anticipation of monetary gain or loss does not associate with positive subjective response to alcohol in binge drinkers. Drug Alcohol Depend. 2021 01 01; 218:108432. PMID: 33250380; PMCID: PMC7750248.
      Citations: 1     Fields:    Translation:Humans
    40. Li J, Murray CH, Weafer J, de Wit H. Subjective Effects of Alcohol Predict Alcohol Choice in Social Drinkers. Alcohol Clin Exp Res. 2020 12; 44(12):2579-2587. PMID: 33201577; PMCID: PMC8076998.
      Citations: 1     Fields:    Translation:Humans
    41. Webber HE, Lopez-Gamundi P, Stamatovich SN, de Wit H, Wardle MC. Using pharmacological manipulations to study the role of dopamine in human reward functioning: A review of studies in healthy adults. Neurosci Biobehav Rev. 2021 01; 120:123-158. PMID: 33202256; PMCID: PMC7855845.
      Citations: 11     Fields:    Translation:HumansAnimals
    42. Radoman M, Crane NA, Gorka SM, Weafer J, Langenecker SA, de Wit H, Phan KL. Striatal activation to monetary reward is associated with alcohol reward sensitivity. Neuropsychopharmacology. 2021 01; 46(2):343-350. PMID: 32505126; PMCID: PMC7852684.
      Citations: 12     Fields:    Translation:Humans
    43. Adam KCS, Doss MK, Pabon E, Vogel EK, de Wit H. ?9-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial. Neuropsychopharmacology. 2020 10; 45(11):1807-1816. PMID: 32386395; PMCID: PMC7608353.
      Citations: 10     Fields:    Translation:Humans
    44. Murray CH, Weafer J, de Wit H. Stability of acute responses to drugs in humans across repeated testing: Findings with alcohol and amphetamine. Drug Alcohol Depend. 2020 07 01; 212:107989. PMID: 32386922; PMCID: PMC7354676.
      Citations: 3     Fields:    Translation:Humans
    45. Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Gordon S, Medland SE, Watson HJ, Bryois J, Hinney A, Mattheisen M, Ripke S, Yao S, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Estivill X, Farmer A, Favaro A, Fichter MM, Fischer K, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Kalsi G, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Lichtenstein P, Norring C, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Murray AD, Nurnberger JI, Preuss U, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson PKE, Nelson EC, Palmer AA, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose RJ, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Wade TD, Heath AC, Montgomery GW, Martin NG, Sullivan PF, Kaprio J, Breen G, Gelernter J, Edenberg HJ, Bulik CM, Agrawal A, Hübel C, Gaspar HA, Leppä VM, Giusti-Rodríguez P, Boehm I, Egberts K, Ehrlich S, Escaramís G, Esko T, Fernández-Aranda F, Föcker M, Guillaume S, Jiménez-Murcia S, Julià A, Kaminská D, Rabionet R, et al. Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addict Biol. 2021 01; 26(1):e12880. PMID: 32064741; PMCID: PMC7429266.
      Citations: 21     Fields:    Translation:Humans
    46. Pabon E, MacKillop J, Palmer AA, de Wit H. Multidimensional latent structure of risk-related phenotypes in healthy young adults. Exp Clin Psychopharmacol. 2020 Feb; 28(1):55-64. PMID: 30998058; PMCID: PMC7233128.
      Citations: 2     Fields:    Translation:Humans
    47. Van Hedger K, Bershad AK, Lee R, de Wit H. Effects of Intranasal Oxytocin on Stress-Induced Cigarette Craving in Daily Smokers. Nicotine Tob Res. 2020 01 27; 22(1):89-95. PMID: 30085292; PMCID: PMC7297012.
      Citations: 8     Fields:    Translation:Humans
    48. Bershad AK, Preller KH, Lee R, Keedy S, Wren-Jarvis J, Bremmer MP, de Wit H. Preliminary Report on the Effects of a Low Dose of LSD on Resting-State Amygdala Functional Connectivity. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 04; 5(4):461-467. PMID: 32033922; PMCID: PMC7150630.
      Citations: 27     Fields:    Translation:Humans
    49. Weafer J, Phan KL, de Wit H. Poor inhibitory control is associated with greater stimulation and less sedation following alcohol. Psychopharmacology (Berl). 2020 Mar; 237(3):825-832. PMID: 31832721; PMCID: PMC7039753.
      Citations: 5     Fields:    Translation:Humans
    50. Meyre D, Mohamed S, Gray JC, Weafer J, MacKillop J, de Wit H. Association between impulsivity traits and body mass index at the observational and genetic epidemiology level. Sci Rep. 2019 11 26; 9(1):17583. PMID: 31772290; PMCID: PMC6879509.
      Citations: 3     Fields:    Translation:Humans
    51. Langenecker SA, Kling LR, Crane NA, Gorka SM, Nusslock R, Damme KSF, Weafer J, de Wit H, Phan KL. Anticipation of monetary reward in amygdala, insula, caudate are predictors of pleasure sensitivity to d-Amphetamine administration. Drug Alcohol Depend. 2020 01 01; 206:107725. PMID: 31757518; PMCID: PMC6980714.
      Citations: 7     Fields:    Translation:Humans
    52. Doss MK, Weafer J, Gallo DA, de Wit H. ?9-Tetrahydrocannabinol During Encoding Impairs Perceptual Details yet Spares Context Effects on Episodic Memory. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 01; 5(1):110-118. PMID: 31668830; PMCID: PMC6954333.
      Citations: 5     Fields:    Translation:Humans
    53. Pabon E, de Wit H. Developing a phone-based measure of impairment after acute oral ?9-tetrahydrocannabinol. J Psychopharmacol. 2019 09; 33(9):1160-1169. PMID: 31407943; PMCID: PMC7303896.
      Citations: 6     Fields:    Translation:HumansAnimals
    54. de Wit H, Bershad AK. MDMA enhances pleasantness of affective touch. Neuropsychopharmacology. 2020 01; 45(1):217-239. PMID: 31391575; PMCID: PMC6879524.
      Citations: 5     Fields:    Translation:Humans
    55. Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong JS, Ip HF, van der Zee MD, Bartels M, Day FR, Fontanillas P, Elson SL, 23andMe Research Team, de Wit H, Davis LK, MacKillop J, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Paus T, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Gillespie NA, Derks EM, Vink JM, Pasman JA, Mägi R, Ramos-Quiroga JA, Ribases M, Munafò MR. Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability. Nat Neurosci. 2019 Jul; 22(7):1196. PMID: 31168101.
      Citations: 4     Fields:    
    56. Schepers ST, Arndt DL, Rogers RD, Hedeker D, de Wit H. Subjective responses to amphetamine in young adults with previous mood elevation experiences. Psychopharmacology (Berl). 2019 Nov; 236(11):3363-3370. PMID: 31209507; PMCID: PMC7053220.
      Citations: 2     Fields:    Translation:Humans
    57. Bershad AK, Schepers ST, Bremmer MP, Lee R, de Wit H. Acute Subjective and Behavioral Effects of Microdoses of Lysergic Acid Diethylamide in Healthy Human Volunteers. Biol Psychiatry. 2019 11 15; 86(10):792-800. PMID: 31331617; PMCID: PMC6814527.
      Citations: 50     Fields:    Translation:HumansAnimalsCTClinical Trials
    58. Van Hedger K, Kushner MJ, Lee R, de Wit H. Oxytocin Reduces Cigarette Consumption in Daily Smokers. Nicotine Tob Res. 2019 05 21; 21(6):799-804. PMID: 29701814; PMCID: PMC6784409.
      Citations: 11     Fields:    Translation:Humans
    59. Weafer J, Van Hedger K, Keedy SK, Nwaokolo N, de Wit H. Methamphetamine acutely alters frontostriatal resting state functional connectivity in healthy young adults. Addict Biol. 2020 05; 25(3):e12775. PMID: 31099141; PMCID: PMC6527344.
      Citations: 10     Fields:    Translation:Humans
    60. Cryan JF, de Wit H. The gut microbiome in psychopharmacology and psychiatry. Psychopharmacology (Berl). 2019 05; 236(5):1407-1409. PMID: 31172224.
      Citations: 4     Fields:    
    61. Bershad AK, Van Hedger K, McGlone F, Walker SC, de Wit H, Mayo LM. Effects of MDMA on attention to positive social cues and pleasantness of affective touch. Neuropsychopharmacology. 2019 09; 44(10):1698-1705. PMID: 31042696; PMCID: PMC6785008.
      Citations: 24     Fields:    Translation:Humans
    62. Weafer J, Crane NA, Gorka SM, Phan KL, de Wit H. Neural correlates of inhibition and reward are negatively associated. Neuroimage. 2019 08 01; 196:188-194. PMID: 30974242; PMCID: PMC6559844.
      Citations: 14     Fields:    Translation:Humans
    63. Gray JC, Sanchez-Roige S, de Wit H, MacKillop J, Palmer AA. Genomic basis of delayed reward discounting. Behav Processes. 2019 May; 162:157-161. PMID: 30876880; PMCID: PMC6980721.
      Citations: 3     Fields:    Translation:HumansAnimals
    64. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA, Abecasis GR. Publisher Correction: Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2019 Mar; 22(3):503. PMID: 30622366.
      Citations:    Fields:    
    65. Sanchez-Roige S, Fontanillas P, Elson SL, Gray JC, de Wit H, MacKillop J, Palmer AA. Genome-Wide Association Studies of Impulsive Personality Traits (BIS-11 and UPPS-P) and Drug Experimentation in up to 22,861 Adult Research Participants Identify Loci in the CACNA1I and CADM2 genes. J Neurosci. 2019 03 27; 39(13):2562-2572. PMID: 30718321; PMCID: PMC6435820.
      Citations: 53     Fields:    Translation:Humans
    66. Van Hedger K, Keedy SK, Schertz KE, Berman MG, de Wit H. Effects of methamphetamine on neural responses to visual stimuli. Psychopharmacology (Berl). 2019 Jun; 236(6):1741-1748. PMID: 30604184; PMCID: PMC6606378.
      Citations: 5     Fields:    Translation:Humans
    67. Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Murray AD, Nurnberger JI, Palotie A, Preuss U, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A, Gäbel W, Männistö S, Müller-Myhsok B, Räikkönen K, Nöthen MM. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nat Neurosci. 2018 12; 21(12):1656-1669. PMID: 30482948; PMCID: PMC6430207.
      Citations: 268     Fields:    Translation:Humans
    68. MacKillop J, Gray JC, Weafer J, Sanchez-Roige S, Palmer AA, de Wit H. Genetic influences on delayed reward discounting: A genome-wide prioritized subset approach. Exp Clin Psychopharmacol. 2019 Feb; 27(1):29-37. PMID: 30265060; PMCID: PMC6908809.
      Citations: 5     Fields:    Translation:Humans
    69. Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong JS, Ip HF, van der Zee MD, Bartels M, Day FR, Fontanillas P, Elson SL, 23andMe Research Team, de Wit H, Davis LK, MacKillop J, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Paus T, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Gillespie NA, Derks EM, Vink JM, Pasman JA, Mägi R, Ramos-Quiroga JA, Ribases M, Munafò MR. GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Nat Neurosci. 2018 09; 21(9):1161-1170. PMID: 30150663; PMCID: PMC6386176.
      Citations: 184     Fields:    Translation:Humans
    70. Doss MK, Weafer J, Ruiz NA, Gallo DA, De Wit H. Alcohol and pharmacologically similar sedatives impair encoding and facilitate consolidation of both recollection and familiarity in episodic memory. Cogn Neurosci. 2018 Jul - Oct; 9(3-4):89-99. PMID: 30044718; PMCID: PMC6309693.
      Citations: 5     Fields:    Translation:Humans
    71. Weafer J, Ross TJ, O'Connor S, Stein EA, de Wit H, Childs E. Striatal activity correlates with stimulant-like effects of alcohol in healthy volunteers. Neuropsychopharmacology. 2018 12; 43(13):2532-2538. PMID: 30093699; PMCID: PMC6224577.
      Citations: 14     Fields:    Translation:Humans
    72. Vena A, King A, Lee R, de Wit H. Intranasal Oxytocin Does Not Modulate Responses to Alcohol in Social Drinkers. Alcohol Clin Exp Res. 2018 09; 42(9):1725-1734. PMID: 29917245; PMCID: PMC6120762.
      Citations: 8     Fields:    Translation:Humans
    73. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA, Abecasis GR. Publisher Correction: Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2018 Jul; 21(7):1018. PMID: 29752479.
      Citations:    Fields:    
    74. de Wit H, Epstein DH, Preston KL. Does human language limit translatability of clinical and preclinical addiction research? Neuropsychopharmacology. 2018 09; 43(10):1985-1988. PMID: 29844475; PMCID: PMC6098131.
      Citations: 8     Fields:    Translation:HumansAnimals
    75. Doss MK, Weafer J, Gallo DA, de Wit H. ?9-Tetrahydrocannabinol at Retrieval Drives False Recollection of Neutral and Emotional Memories. Biol Psychiatry. 2018 11 15; 84(10):743-750. PMID: 29884456.
      Citations: 13     Fields:    Translation:Humans
    76. Bershad AK, Miller MA, Norman GJ, de Wit H. Effects of opioid- and non-opioid analgesics on responses to psychosocial stress in humans. Horm Behav. 2018 06; 102:41-47. PMID: 29673620; PMCID: PMC6004330.
      Citations: 16     Fields:    Translation:Humans
    77. Crane NA, Gorka SM, Weafer J, Langenecker SA, de Wit H, Phan KL. Neural activation to monetary reward is associated with amphetamine reward sensitivity. Neuropsychopharmacology. 2018 07; 43(8):1738-1744. PMID: 29581536; PMCID: PMC6006344.
      Citations: 10     Fields:    Translation:Humans
    78. de Wit H, Sayette M. Considering the context: social factors in responses to drugs in humans. Psychopharmacology (Berl). 2018 04; 235(4):935-945. PMID: 29470605; PMCID: PMC5871591.
      Citations: 17     Fields:    Translation:HumansAnimals
    79. Curran HV, Nutt D, de Wit H. Psychedelics and related drugs: therapeutic possibilities, mechanisms and regulation. Psychopharmacology (Berl). 2018 02; 235(2):373-375. PMID: 29445838.
      Citations: 10     Fields:    Translation:HumansAnimals
    80. Bershad AK, Ruiz NA, de Wit H. Effects of Buprenorphine on Responses to Emotional Stimuli in Individuals with a Range of Mood Symptomatology. Int J Neuropsychopharmacol. 2018 02 01; 21(2):120-127. PMID: 29025085; PMCID: PMC5793829.
      Citations: 5     Fields:    Translation:Humans
    81. Van Hedger K, Keedy SK, de Wit H, Mayo LM, Heilig M. Neural responses to cues paired with methamphetamine in healthy volunteers. Neuropsychopharmacology. 2018 07; 43(8):1732-1737. PMID: 29463908; PMCID: PMC6006246.
      Citations: 6     Fields:    Translation:Humans
    82. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA, Abecasis GR. Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nat Neurosci. 2018 01; 21(1):16-18. PMID: 29230059; PMCID: PMC6984001.
      Citations: 52     Fields:    Translation:Humans
    83. Gray JC, MacKillop J, Weafer J, Hernandez KM, Gao J, Palmer AA, de Wit H. Genetic analysis of impulsive personality traits: Examination of a priori candidates and genome-wide variation. Psychiatry Res. 2018 01; 259:398-404. PMID: 29120849; PMCID: PMC5742029.
      Citations: 19     Fields:    Translation:Humans
    84. Crane NA, Gorka SM, Weafer J, Langenecker SA, de Wit H, Phan KL. Preliminary Evidence for Disrupted Nucleus Accumbens Reactivity and Connectivity to Reward in Binge Drinkers. Alcohol Alcohol. 2017 Nov 01; 52(6):647-654. PMID: 29016710; PMCID: PMC5860287.
      Citations: 12     Fields:    Translation:Humans
    85. Sanchez-Roige S, Fontanillas P, Elson SL, 23andMe Research Team, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA. Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry. Addict Biol. 2019 01; 24(1):121-131. PMID: 29058377; PMCID: PMC6988186.
      Citations: 54     Fields:    Translation:HumansPHPublic Health
    86. Palmisano AN, Hudd EC, McQuade CM, de Wit H, Astur RS. The effects of nicotine on conditioning, extinction, and reinstatement in humans. Addict Behav. 2018 Feb; 77:51-58. PMID: 28957728.
      Citations: 3     Fields:    Translation:Humans
    87. Van Hedger K, Bershad AK, de Wit H. Pharmacological challenge studies with acute psychosocial stress. Psychoneuroendocrinology. 2017 Nov; 85:123-133. PMID: 28858691; PMCID: PMC5623124.
      Citations: 9     Fields:    Translation:Humans
    88. Doss MK, Weafer J, Gallo DA, de Wit H. MDMA Impairs Both the Encoding and Retrieval of Emotional Recollections. Neuropsychopharmacology. 2018 03; 43(4):791-800. PMID: 28825422; PMCID: PMC5809786.
      Citations: 15     Fields:    Translation:Humans
    89. Weafer J, Lyon N, Hedeker D, de Wit H. Sweet taste liking is associated with subjective response to amphetamine in women but not men. Psychopharmacology (Berl). 2017 Nov; 234(21):3185-3194. PMID: 28762072; PMCID: PMC5660927.
      Citations: 9     Fields:    Translation:HumansAnimals
    90. Bidwell LC, Gray JC, Weafer J, Palmer AA, de Wit H, MacKillop J. Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):458-466. PMID: 28512748; PMCID: PMC5690554.
      Citations: 11     Fields:    Translation:Humans
    91. Arndt DL, de Wit H. Cannabidiol Does Not Dampen Responses to Emotional Stimuli in Healthy Adults. Cannabis Cannabinoid Res. 2017; 2(1):105-113. PMID: 28861510; PMCID: PMC5569582.
      Citations: 21     Fields:    
    92. Childs E, Lutz JA, de Wit H. Dose-related effects of delta-9-THC on emotional responses to acute psychosocial stress. Drug Alcohol Depend. 2017 08 01; 177:136-144. PMID: 28599212; PMCID: PMC6349031.
      Citations: 40     Fields:    Translation:Humans
    93. Cryan JF, de Wit H. Special issue: recognizing the lifetime scientific contributions of Athina Markou. Psychopharmacology (Berl). 2017 05; 234(9-10):1311-1313. PMID: 28421256; PMCID: PMC5473252.
      Citations:    Fields:    
    94. Bershad AK, Miller MA, de Wit H. MDMA does not alter responses to the Trier Social Stress Test in humans. Psychopharmacology (Berl). 2017 Jul; 234(14):2159-2166. PMID: 28432376; PMCID: PMC5984654.
      Citations: 6     Fields:    Translation:Humans
    95. Weafer J, Gorka SM, Hedeker D, Dzemidzic M, Kareken DA, Phan KL, de Wit H. Associations Between Behavioral and Neural Correlates of Inhibitory Control and Amphetamine Reward Sensitivity. Neuropsychopharmacology. 2017 Aug; 42(9):1905-1913. PMID: 28303900; PMCID: PMC5520786.
      Citations: 17     Fields:    Translation:Humans
    96. Childs E, Astur RS, de Wit H. Virtual reality conditioned place preference using monetary reward. Behav Brain Res. 2017 03 30; 322(Pt A):110-114. PMID: 28108321; PMCID: PMC5335910.
      Citations: 5     Fields:    Translation:Humans
    97. Miller MA, Bershad A, King AC, Lee R, de Wit H. Intranasal oxytocin dampens cue-elicited cigarette craving in daily smokers: a pilot study. Behav Pharmacol. 2016 12; 27(8):697-703. PMID: 27661192; PMCID: PMC5089916.
      Citations: 17     Fields:    Translation:Humans
    98. Shaham Y, de Wit H. Lost in Translation: CRF1 Receptor Antagonists and Addiction Treatment. Neuropsychopharmacology. 2016 11; 41(12):2795-2797. PMID: 27312404; PMCID: PMC5061894.
      Citations: 27     Fields:    Translation:Humans
    99. Childs E, de Wit H. Alcohol-induced place conditioning in moderate social drinkers. Addiction. 2016 12; 111(12):2157-2165. PMID: 27447940; PMCID: PMC5226878.
      Citations: 12     Fields:    Translation:Humans
    100. Bershad AK, Miller MA, Baggott MJ, de Wit H. The effects of MDMA on socio-emotional processing: Does MDMA differ from other stimulants? J Psychopharmacol. 2016 12; 30(12):1248-1258. PMID: 27562198; PMCID: PMC8753974.
      Citations: 40     Fields:    Translation:Humans
    101. Cavallo JS, Mayo LM, de Wit H. Acquisition of Conditioning between Methamphetamine and Cues in Healthy Humans. PLoS One. 2016; 11(8):e0161541. PMID: 27548681; PMCID: PMC4993385.
      Citations: 2     Fields:    Translation:Humans
    102. Francis SM, Kirkpatrick MG, de Wit H, Jacob S. Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration. Psychoneuroendocrinology. 2016 12; 74:92-100. PMID: 27592327.
      Citations: 17     Fields:    Translation:Humans
    103. MacKillop J, Weafer J, C Gray J, Oshri A, Palmer A, de Wit H. The latent structure of impulsivity: impulsive choice, impulsive action, and impulsive personality traits. Psychopharmacology (Berl). 2016 Sep; 233(18):3361-70. PMID: 27449350; PMCID: PMC5204128.
      Citations: 135     Fields:    Translation:Humans
    104. Childs E, Bershad AK, de Wit H. Effects of d-amphetamine upon psychosocial stress responses. J Psychopharmacol. 2016 07; 30(7):608-15. PMID: 27235381.
      Citations: 7     Fields:    Translation:Humans
    105. Cavallo JS, Ruiz NA, de Wit H. Extinction of Conditioned Responses to Methamphetamine-Associated Stimuli in Healthy Humans. Psychopharmacology (Berl). 2016 07; 233(13):2489-502. PMID: 27113223; PMCID: PMC4909474.
      Citations: 3     Fields:    Translation:HumansAnimals
    106. Steckler T, Curran HV, de Wit H, Howes O, Hoyer D, Lucki I, Miczek KA, Morrow AL, Price LH, Robbins TW. Editorial: Reporting guidelines for psychopharmacology. Psychopharmacology (Berl). 2016 Apr; 233(7):1131-4. PMID: 26915651.
      Citations: 2     Fields:    
    107. Mayo LM, de Wit H. Acquisition of Conditioned Responses to a Novel Alcohol-Paired Cue in Social Drinkers. J Stud Alcohol Drugs. 2016 Mar; 77(2):317-26. PMID: 26997190; PMCID: PMC4803664.
      Citations: 11     Fields:    Translation:Humans
    108. Bershad AK, Weafer JJ, Kirkpatrick MG, Wardle MC, Miller MA, de Wit H. Oxytocin receptor gene variation predicts subjective responses to MDMA. Soc Neurosci. 2016 12; 11(6):592-9. PMID: 26787430; PMCID: PMC4988944.
      Citations: 17     Fields:    Translation:Humans
    109. Smith CT, Weafer J, Cowan RL, Kessler RM, Palmer AA, de Wit H, Zald DH. Individual differences in timing of peak positive subjective responses to d-amphetamine: Relationship to pharmacokinetics and physiology. J Psychopharmacol. 2016 Apr; 30(4):330-43. PMID: 26880226; PMCID: PMC5049703.
      Citations: 6     Fields:    Translation:Humans
    110. Wardle MC, Bershad AK, de Wit H. Naltrexone alters the processing of social and emotional stimuli in healthy adults. Soc Neurosci. 2016 12; 11(6):579-91. PMID: 26710657; PMCID: PMC4958027.
      Citations: 18     Fields:    Translation:Humans
    111. Weafer J, Gallo DA, de Wit H. Acute Effects of Alcohol on Encoding and Consolidation of Memory for Emotional Stimuli. J Stud Alcohol Drugs. 2016 Jan; 77(1):86-94. PMID: 26751358; PMCID: PMC4711324.
      Citations: 12     Fields:    Translation:Humans
    112. Temple JL, Ziegler AM, Martin C, de Wit H. Subjective Responses to Caffeine Are Influenced by Caffeine Dose, Sex, and Pubertal Stage. J Caffeine Res. 2015 Dec 01; 5(4):167-175. PMID: 26649252; PMCID: PMC4663646.
      Citations: 9     
    113. Wardle MC, Marcus BA, de Wit H. A Preliminary Investigation of Individual Differences in Subjective Responses to D-Amphetamine, Alcohol, and Delta-9-Tetrahydrocannabinol Using a Within-Subjects Randomized Trial. PLoS One. 2015; 10(10):e0140501. PMID: 26513587; PMCID: PMC4626040.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    114. de Wit H, Gorka SM, Phan KL. The Ups and Downs of 3,4-Methylenedioxymethamphetamine: Linking Subjective Effects to Spontaneous Brain Function. Biol Psychiatry. 2015 Oct 15; 78(8):519-21. PMID: 26386625.
      Citations: 1     Fields:    Translation:Humans
    115. Kirkpatrick MG, Goldenson NI, Kapadia N, Kahler CW, de Wit H, Swift RM, McGeary JE, Sussman S, Leventhal AM. Emotional traits predict individual differences in amphetamine-induced positive mood in healthy volunteers. Psychopharmacology (Berl). 2016 Jan; 233(1):89-97. PMID: 26429791; PMCID: PMC4703469.
      Citations: 7     Fields:    Translation:Humans
    116. de Wit HM, Engwerda EE, Tack CJ, de Galan BE. Insulin administered by needle-free jet injection corrects marked hyperglycaemia faster in overweight or obese patients with diabetes. Diabetes Obes Metab. 2015 Nov; 17(11):1093-9. PMID: 26259978.
      Citations: 6     Fields:    Translation:Humans
    117. VanderBroek L, Acker J, Palmer AA, de Wit H, MacKillop J. Interrelationships among parental family history of substance misuse, delay discounting, and personal substance use. Psychopharmacology (Berl). 2016 Jan; 233(1):39-48. PMID: 26395990; PMCID: PMC4830143.
      Citations: 30     Fields:    Translation:Humans
    118. Bershad AK, Seiden JA, de Wit H. Effects of buprenorphine on responses to social stimuli in healthy adults. Psychoneuroendocrinology. 2016 Jan; 63:43-9. PMID: 26409030; PMCID: PMC4695221.
      Citations: 19     Fields:    Translation:Humans
    119. de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Amin N, Gordon SD, Hansell NK, Hart AB, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abdellaoui A, Abecasis GR, Adkins DE, Agrawal A, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Smith GD, Davies G, de Wit H, Ding J, Engelhardt BE, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Mbarek H, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Nivard MG, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Generation Scotland, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Wilson JF, Bierut LJ, Hettema JM, Grabe HJ, Penninx BW, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, McGue M, Martin NG, Boomsma DI, van den Berg SM, Esko T, Seppälä I, Allik J, Eriksson JG, Lehtimäki T, Pulkki-Råback L, Räikkönen K, Keltikangas-Järvinen L, Terracciano A. Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behav Genet. 2016 Mar; 46(2):170-82. PMID: 26362575; PMCID: PMC4751159.
      Citations: 56     Fields:    Translation:Humans
    120. Miller MA, Bershad AK, de Wit H. Drug effects on responses to emotional facial expressions: recent findings. Behav Pharmacol. 2015 Sep; 26(6):571-9. PMID: 26226144; PMCID: PMC4905685.
      Citations: 11     Fields:    Translation:Humans
    121. Genetics of Personality Consortium, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Amin N, Gordon SD, Hansell NK, Hart AB, Huffman JE, Konte B, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abecasis GR, Adkins DE, Agrawal A, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Davey Smith G, Davies G, de Wit H, Ding J, Engelhardt BE, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Wilson JF, Bierut LJ, Hettema JM, Grabe HJ, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, McGue M, Penninx BW, Martin NG, Boomsma DI, van den Berg SM, Esko T, Seppälä I, Lahti J, Allik J, Eriksson JG, Lehtimäki T, Pulkki-Råback L, Räikkönen K, Keltikangas-Järvinen L, Terracciano A. Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA Psychiatry. 2015 Jul; 72(7):642-50. PMID: 25993607; PMCID: PMC4667957.
      Citations: 110     Fields:    Translation:Humans
    122. Kirkpatrick MG, Seiden JA, de Wit H, Bershad AK. Effects of acute doses of prosocial drugs methamphetamine and alcohol on plasma oxytocin levels. J Clin Psychopharmacol. 2015 Jun; 35(3):308-12. PMID: 25853370; PMCID: PMC4414800.
      Citations: 13     Fields:    Translation:Humans
    123. Weafer J, De Arcangelis J, de Wit H. Sex differences in behavioral impulsivity in at-risk and non-risk drinkers. Front Psychiatry. 2015; 6:72. PMID: 26029121; PMCID: PMC4429551.
      Citations: 10     
    124. Baggott MJ, Kirkpatrick MG, Bedi G, de Wit H. Intimate insight: MDMA changes how people talk about significant others. J Psychopharmacol. 2015 Jun; 29(6):669-77. PMID: 25922420; PMCID: PMC4698152.
      Citations: 22     Fields:    Translation:Humans
    125. Yarosh HL, Meda SA, de Wit H, Hart AB, Pearlson GD. Multivariate analysis of subjective responses to d-amphetamine in healthy volunteers finds novel genetic pathway associations. Psychopharmacology (Berl). 2015 Aug; 232(15):2781-94. PMID: 25843748; PMCID: PMC4504822.
      Citations: 5     Fields:    Translation:Humans
    126. Kirkpatrick M, Delton AW, Robertson TE, de Wit H. Prosocial effects of MDMA: A measure of generosity. J Psychopharmacol. 2015 Jun; 29(6):661-8. PMID: 25735993.
      Citations: 21     Fields:    Translation:Humans
    127. Ballard ME, Weafer J, Gallo DA, de Wit H. Effects of acute methamphetamine on emotional memory formation in humans: encoding vs consolidation. PLoS One. 2015; 10(2):e0117062. PMID: 25679982; PMCID: PMC4332474.
      Citations: 5     Fields:    Translation:Humans
    128. Mayo LM, de Wit H. Acquisition of responses to a methamphetamine-associated cue in healthy humans: self-report, behavioral, and psychophysiological measures. Neuropsychopharmacology. 2015 Jun; 40(7):1734-41. PMID: 25601231; PMCID: PMC4915257.
      Citations: 24     Fields:    Translation:Humans
    129. Tasali E, Leproult R, Stuhr KL, Doncheck E, de Wit H, Hillard CJ, Van Cauter E, Hanlon EC. Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. J Clin Endocrinol Metab. 2015 Jan; 100(1):220-6. PMID: 25368979; PMCID: PMC5399498.
      Citations: 36     Fields:    Translation:Humans
    130. Gorka SM, Fitzgerald DA, de Wit H, Phan KL. Cannabinoid modulation of amygdala subregion functional connectivity to social signals of threat. Int J Neuropsychopharmacol. 2014 Dec 28; 18(3). PMID: 25548107; PMCID: PMC4360235.
      Citations: 17     Fields:    Translation:Humans
    131. Bershad AK, Jaffe JH, Childs E, de Wit H. Opioid partial agonist buprenorphine dampens responses to psychosocial stress in humans. Psychoneuroendocrinology. 2015 Feb; 52:281-8. PMID: 25544740; PMCID: PMC4297554.
      Citations: 32     Fields:    Translation:Humans
    132. Kirkpatrick MG, de Wit H. MDMA: a social drug in a social context. Psychopharmacology (Berl). 2015 Mar; 232(6):1155-63. PMID: 25281223; PMCID: PMC4339498.
      Citations: 18     Fields:    Translation:Humans
    133. Gorka SM, Fitzgerald DA, de Wit H, Angstadt M, Phan KL. Opioid modulation of resting-state anterior cingulate cortex functional connectivity. J Psychopharmacol. 2014 Dec; 28(12):1115-24. PMID: 25237122; PMCID: PMC5613932.
      Citations: 11     Fields:    Translation:Humans
    134. Childs E, White TL, de Wit H. Personality traits modulate emotional and physiological responses to stress. Behav Pharmacol. 2014 Sep; 25(5-6):493-502. PMID: 25036730; PMCID: PMC4119514.
      Citations: 20     Fields:    Translation:Humans
    135. Weafer J, Burkhardt A, de Wit H. Sweet taste liking is associated with impulsive behaviors in humans. Front Behav Neurosci. 2014; 8:228. PMID: 24987343; PMCID: PMC4060557.
      Citations: 9     
    136. Wardle MC, Fitzgerald DA, Angstadt M, Rabinak CA, de Wit H, Phan KL. Effects of oxycodone on brain responses to emotional images. Psychopharmacology (Berl). 2014 Nov; 231(22):4403-15. PMID: 24800897; PMCID: PMC6720110.
      Citations: 8     Fields:    Translation:Humans
    137. Childs E, de Wit H. Regular exercise is associated with emotional resilience to acute stress in healthy adults. Front Physiol. 2014; 5:161. PMID: 24822048; PMCID: PMC4013452.
      Citations: 58     
    138. Kirkpatrick MG, Francis SM, Lee R, de Wit H, Jacob S. Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans. Psychoneuroendocrinology. 2014 Aug; 46:23-31. PMID: 24882155; PMCID: PMC4088952.
      Citations: 28     Fields:    Translation:Humans
    139. Wardle MC, de Wit H. MDMA alters emotional processing and facilitates positive social interaction. Psychopharmacology (Berl). 2014 Oct; 231(21):4219-29. PMID: 24728603; PMCID: PMC4194242.
      Citations: 35     Fields:    Translation:Humans
    140. Hart AB, Gamazon ER, Engelhardt BE, Sklar P, Hultman CM, Sullivan PF, Neale BM, Faraone SV, Psychiatric Genomics Consortium: ADHD Subgroup, de Wit H, Cox NJ, Palmer AA, Kähler AK. Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):5968-73. PMID: 24711425; PMCID: PMC4000861.
      Citations: 14     Fields:    Translation:Humans
    141. Bedi G, Cecchi GA, Slezak DF, Carrillo F, Sigman M, de Wit H. A window into the intoxicated mind? Speech as an index of psychoactive drug effects. Neuropsychopharmacology. 2014 Sep; 39(10):2340-8. PMID: 24694926; PMCID: PMC4138742.
      Citations: 33     Fields:    Translation:Humans
    142. Wardle MC, Kirkpatrick MG, de Wit H. 'Ecstasy' as a social drug: MDMA preferentially affects responses to emotional stimuli with social content. Soc Cogn Affect Neurosci. 2014 Aug; 9(8):1076-81. PMID: 24682132; PMCID: PMC4127030.
      Citations: 24     Fields:    Translation:Humans
    143. Kirkpatrick MG, Baggott MJ, Mendelson JE, Galloway GP, Liechti ME, de Wit H, Hysek CM. MDMA effects consistent across laboratories. Psychopharmacology (Berl). 2014 Oct; 231(19):3899-905. PMID: 24633447; PMCID: PMC4161650.
      Citations: 26     Fields:    Translation:Humans
    144. Clark DB, de Wit H, Iacono WG. ADHD, impulsivity and alcohol abuse: methods, results, and implications. Exp Clin Psychopharmacol. 2014 Apr; 22(2):141-3. PMID: 24611836; PMCID: PMC4141644.
      Citations:    Fields:    Translation:Humans
    145. de Wit H, Hoek JB. Farewell to Drs. Ivan Diamond and T.-K. Li. Alcohol Clin Exp Res. 2014 Jul; 38(7):1821. PMID: 24588447.
      Citations:    Fields:    Translation:Humans
    146. Weafer J, Gallo DA, de Wit H. Amphetamine fails to alter cued recollection of emotional images: study of encoding, retrieval, and state-dependency. PLoS One. 2014; 9(2):e90423. PMID: 24587355; PMCID: PMC3937372.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    147. Gallo DA, de Wit H, Ballard ME. Amphetamine increases errors during episodic memory retrieval. J Clin Psychopharmacol. 2014 Feb; 34(1):85-92. PMID: 24135845; PMCID: PMC4244906.
      Citations: 16     Fields:    Translation:Humans
    148. Kirkpatrick MG, Lee R, Wardle MC, Jacob S, de Wit H. Effects of MDMA and Intranasal oxytocin on social and emotional processing. Neuropsychopharmacology. 2014 Jun; 39(7):1654-63. PMID: 24448644; PMCID: PMC4023138.
      Citations: 53     Fields:    Translation:Humans
    149. Frye CG, Wardle MC, Norman GJ, de Wit H. MDMA decreases the effects of simulated social rejection. Pharmacol Biochem Behav. 2014 Feb; 117:1-6. PMID: 24316346; PMCID: PMC3910346.
      Citations: 36     Fields:    Translation:Humans
    150. Weafer J, de Wit H. Sex differences in impulsive action and impulsive choice. Addict Behav. 2014 Nov; 39(11):1573-1579. PMID: 24286704; PMCID: PMC4012004.
      Citations: 80     Fields:    Translation:HumansAnimals
    151. Weafer J, Baggott MJ, de Wit H. Test-retest reliability of behavioral measures of impulsive choice, impulsive action, and inattention. Exp Clin Psychopharmacol. 2013 Dec; 21(6):475-81. PMID: 24099351; PMCID: PMC4266373.
      Citations: 78     Fields:    Translation:HumansCTClinical Trials
    152. Weafer J, de Wit H. Inattention, impulsive action, and subjective response to D-amphetamine. Drug Alcohol Depend. 2013 Nov 01; 133(1):127-33. PMID: 23790566; PMCID: PMC3786022.
      Citations: 22     Fields:    Translation:Humans
    153. Heinz AJ, de Wit H, Lilje TC, Kassel JD. The combined effects of alcohol, caffeine, and expectancies on subjective experience, impulsivity, and risk-taking. Exp Clin Psychopharmacol. 2013 Jun; 21(3):222-34. PMID: 23750693; PMCID: PMC4354945.
      Citations: 26     Fields:    Translation:Humans
    154. Kirkpatrick MG, de Wit H. In the company of others: social factors alter acute alcohol effects. Psychopharmacology (Berl). 2013 Nov; 230(2):215-26. PMID: 23712603; PMCID: PMC3800265.
      Citations: 40     Fields:    Translation:Humans
    155. Napier TC, Herrold AA, de Wit H. Using conditioned place preference to identify relapse prevention medications. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt A):2081-6. PMID: 23680702; PMCID: PMC3815959.
      Citations: 34     Fields:    Translation:HumansAnimalsPHPublic Health
    156. Baggott MJ, Childs E, Hart AB, de Bruin E, Palmer AA, Wilkinson JE, de Wit H. Psychopharmacology of theobromine in healthy volunteers. Psychopharmacology (Berl). 2013 Jul; 228(1):109-18. PMID: 23420115; PMCID: PMC3672386.
      Citations: 26     Fields:    Translation:Humans
    157. Mayo LM, Fraser D, Childs E, Momenan R, Hommer DW, de Wit H, Heilig M. Conditioned preference to a methamphetamine-associated contextual cue in humans. Neuropsychopharmacology. 2013 May; 38(6):921-9. PMID: 23416857; PMCID: PMC3629404.
      Citations: 24     Fields:    Translation:Humans
    158. Kirkpatrick MG, Johanson CE, de Wit H. Personality and the acute subjective effects of d-amphetamine in humans. J Psychopharmacol. 2013 Mar; 27(3):256-64. PMID: 23343596; PMCID: PMC4241296.
      Citations: 18     Fields:    Translation:Humans
    159. Wardle MC, de Wit H, Penton-Voak I, Lewis G, Munafò MR. Lack of association between COMT and working memory in a population-based cohort of healthy young adults. Neuropsychopharmacology. 2013 Jun; 38(7):1253-63. PMID: 23337869; PMCID: PMC3656369.
      Citations: 31     Fields:    Translation:Humans
    160. Zorrilla EP, Heilig M, de Wit H, Shaham Y. Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. Drug Alcohol Depend. 2013 Mar 01; 128(3):175-86. PMID: 23294766; PMCID: PMC3596012.
      Citations: 48     Fields:    Translation:HumansAnimals
    161. Wardle MC, Hart AB, Palmer AA, de Wit H. Does COMT genotype influence the effects of d-amphetamine on executive functioning? Genes Brain Behav. 2013 Feb; 12(1):13-20. PMID: 23231539; PMCID: PMC3553317.
      Citations: 15     Fields:    Translation:Humans
    162. Morean ME, de Wit H, King AC, Sofuoglu M, Rueger SY, O'Malley SS. The drug effects questionnaire: psychometric support across three drug types. Psychopharmacology (Berl). 2013 May; 227(1):177-92. PMID: 23271193; PMCID: PMC3624068.
      Citations: 121     Fields:    Translation:Humans
    163. Conrad M, Wardle M, King A, de Wit H. Relationship of self-reported and acute stress to smoking in emerging adult smokers. J Clin Psychol. 2013 Jul; 69(7):710-7. PMID: 23280768; PMCID: PMC4795009.
      Citations: 3     Fields:    Translation:Humans
    164. Ballard ME, Gallo DA, de Wit H. Pre-encoding administration of amphetamine or THC preferentially modulates emotional memory in humans. Psychopharmacology (Berl). 2013 Apr; 226(3):515-29. PMID: 23224510; PMCID: PMC3595317.
      Citations: 10     Fields:    Translation:Humans
    165. Heinz AJ, Lilje TC, Kassel JD, de Wit H. Quantifying reinforcement value and demand for psychoactive substances in humans. Curr Drug Abuse Rev. 2012 Dec; 5(4):257-72. PMID: 23062106; PMCID: PMC3566575.
      Citations: 28     Fields:    Translation:Humans
    166. Hart AB, Engelhardt BE, Wardle MC, Sokoloff G, Stephens M, de Wit H, Palmer AA. Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). PLoS One. 2012; 7(8):e42646. PMID: 22952603; PMCID: PMC3429486.
      Citations: 54     Fields:    Translation:Humans
    167. Dlugos A, Childs E, Stuhr KL, Hillard CJ, de Wit H. Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans. Neuropsychopharmacology. 2012 Oct; 37(11):2416-27. PMID: 22763622; PMCID: PMC3442338.
      Citations: 78     Fields:    Translation:Humans
    168. Wardle MC, Treadway MT, de Wit H. Caffeine increases psychomotor performance on the effort expenditure for rewards task. Pharmacol Biochem Behav. 2012 Oct; 102(4):526-31. PMID: 22750066; PMCID: PMC3578395.
      Citations: 9     Fields:    Translation:Humans
    169. Metrik J, Kahler CW, Reynolds B, McGeary JE, Monti PM, Haney M, de Wit H, Rohsenow DJ. Balanced placebo design with marijuana: pharmacological and expectancy effects on impulsivity and risk taking. Psychopharmacology (Berl). 2012 Oct; 223(4):489-99. PMID: 22588253; PMCID: PMC3829473.
      Citations: 66     Fields:    Translation:Humans
    170. Ballard ME, Bedi G, de Wit H. Effects of delta-9-tetrahydrocannabinol on evaluation of emotional images. J Psychopharmacol. 2012 Oct; 26(10):1289-98. PMID: 22585232; PMCID: PMC3664416.
      Citations: 19     Fields:    Translation:Humans
    171. de Wit H, Phillips TJ. Do initial responses to drugs predict future use or abuse? Neurosci Biobehav Rev. 2012 Jul; 36(6):1565-76. PMID: 22542906; PMCID: PMC3372699.
      Citations: 101     Fields:    Translation:HumansAnimals
    172. Yip SW, Doherty J, Wakeley J, Saunders K, Tzagarakis C, de Wit H, Goodwin GM, Rogers RD. Reduced subjective response to acute ethanol administration among young men with a broad bipolar phenotype. Neuropsychopharmacology. 2012 Jul; 37(8):1808-15. PMID: 22491350; PMCID: PMC3376329.
      Citations: 18     Fields:    Translation:Humans
    173. Childs E, Roche DJ, King AC, de Wit H. Varenicline potentiates alcohol-induced negative subjective responses and offsets impaired eye movements. Alcohol Clin Exp Res. 2012 May; 36(5):906-14. PMID: 22339626; PMCID: PMC3342420.
      Citations: 26     Fields:    Translation:Humans
    174. Hart AB, de Wit H, Palmer AA. Genetic factors modulating the response to stimulant drugs in humans. Curr Top Behav Neurosci. 2012; 12:537-77. PMID: 22261702; PMCID: PMC3388157.
      Citations: 14     Fields:    Translation:Humans
    175. Palmer AA, de Wit H. Translational genetic approaches to substance use disorders: bridging the gap between mice and humans. Hum Genet. 2012 Jun; 131(6):931-9. PMID: 22170288; PMCID: PMC3352994.
      Citations: 7     Fields:    Translation:HumansAnimals
    176. Rabinak CA, Sripada CS, Angstadt M, de Wit H, Phan KL. Cannabinoid modulation of subgenual anterior cingulate cortex activation during experience of negative affect. J Neural Transm (Vienna). 2012 Jun; 119(6):701-7. PMID: 22160489; PMCID: PMC4242592.
      Citations: 14     Fields:    Translation:Humans
    177. Childs E, de Wit H. Contextual conditioning enhances the psychostimulant and incentive properties of d-amphetamine in humans. Addict Biol. 2013 Nov; 18(6):985-92. PMID: 22129527; PMCID: PMC4242554.
      Citations: 24     Fields:    Translation:HumansAnimals
    178. Wardle MC, Treadway MT, Mayo LM, Zald DH, de Wit H. Amping up effort: effects of d-amphetamine on human effort-based decision-making. J Neurosci. 2011 Nov 16; 31(46):16597-602. PMID: 22090487; PMCID: PMC3234999.
      Citations: 115     Fields:    Translation:Humans
    179. de Wit H. Sex hormones: a new treatment for cocaine abuse? Neuropsychopharmacology. 2011 Oct; 36(11):2155-6. PMID: 21918518; PMCID: PMC3176577.
      Citations: 3     Fields:    Translation:Animals
    180. Wardle MC, de Wit H. Effects of amphetamine on reactivity to emotional stimuli. Psychopharmacology (Berl). 2012 Mar; 220(1):143-53. PMID: 21947316; PMCID: PMC3277682.
      Citations: 25     Fields:    Translation:Humans
    181. Wardle MC, Yang A, de Wit H. Effect of d-amphetamine on post-error slowing in healthy volunteers. Psychopharmacology (Berl). 2012 Mar; 220(1):109-15. PMID: 21894485; PMCID: PMC4241763.
      Citations: 12     Fields:    Translation:Humans
    182. Childs E, O'Connor S, de Wit H. Bidirectional interactions between acute psychosocial stress and acute intravenous alcohol in healthy men. Alcohol Clin Exp Res. 2011 Oct; 35(10):1794-803. PMID: 21762177; PMCID: PMC3183385.
      Citations: 30     Fields:    Translation:Humans
    183. Ballard ME, Gallo DA, de Wit H. Psychoactive drugs and false memory: comparison of dextroamphetamine and d-9-tetrahydrocannabinol on false recognition. Psychopharmacology (Berl). 2012 Jan; 219(1):15-24. PMID: 21647577; PMCID: PMC4244903.
      Citations: 15     Fields:    Translation:Humans
    184. Wignall ND, de Wit H. Effects of nicotine on attention and inhibitory control in healthy nonsmokers. Exp Clin Psychopharmacol. 2011 Jun; 19(3):183-91. PMID: 21480731; PMCID: PMC4266322.
      Citations: 30     Fields:    Translation:Humans
    185. King AC, de Wit H, McNamara PJ, Cao D. Rewarding, stimulant, and sedative alcohol responses and relationship to future binge drinking. Arch Gen Psychiatry. 2011 Apr; 68(4):389-99. PMID: 21464363; PMCID: PMC4633413.
      Citations: 238     Fields:    Translation:Humans
    186. Bedi G, Preston KL, Epstein DH, Heishman SJ, Marrone GF, Shaham Y, de Wit H. Incubation of cue-induced cigarette craving during abstinence in human smokers. Biol Psychiatry. 2011 Apr 01; 69(7):708-11. PMID: 20817135; PMCID: PMC3027849.
      Citations: 118     Fields:    Translation:Humans
    187. Wardle M, Cederbaum K, de Wit H. Quantifying talk: developing reliable measures of verbal productivity. Behav Res Methods. 2011 Mar; 43(1):168-78. PMID: 21287128; PMCID: PMC3049967.
      Citations: 7     Fields:    Translation:Humans
    188. Wardle MC, de Wit H, Munafò MR. Effect of social stress during acute nicotine abstinence. Psychopharmacology (Berl). 2011 Nov; 218(1):39-48. PMID: 21234550; PMCID: PMC3094594.
      Citations: 16     Fields:    Translation:Humans
    189. Ballard ME, de Wit H. Combined effects of acute, very-low-dose ethanol and delta(9)-tetrahydrocannabinol in healthy human volunteers. Pharmacol Biochem Behav. 2011 Feb; 97(4):627-31. PMID: 21110996; PMCID: PMC3018238.
      Citations: 25     Fields:    Translation:Humans
    190. Mahler SV, de Wit H. Cue-reactors: individual differences in cue-induced craving after food or smoking abstinence. PLoS One. 2010 Nov 10; 5(11):e15475. PMID: 21085667; PMCID: PMC2978100.
      Citations: 39     Fields:    Translation:HumansCTClinical Trials
    191. Bedi G, Hyman D, de Wit H. Is ecstasy an "empathogen"? Effects of ±3,4-methylenedioxymethamphetamine on prosocial feelings and identification of emotional states in others. Biol Psychiatry. 2010 Dec 15; 68(12):1134-40. PMID: 20947066; PMCID: PMC2997873.
      Citations: 88     Fields:    Translation:Humans
    192. Yang A, Childs E, Palmer AA, de Wit H. More on ADORA. Psychopharmacology (Berl). 2010 Dec; 212(4):699-700. PMID: 20802997; PMCID: PMC4243305.
      Citations: 2     Fields:    Translation:Humans
    193. Comer SD, Bickel WK, Yi R, de Wit H, Higgins ST, Wenger GR, Johanson CE, Kreek MJ. Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society. Behav Pharmacol. 2010 Jul; 21(4):251-77. PMID: 20664330; PMCID: PMC2913311.
      Citations: 12     Fields:    Translation:Humans
    194. Yang A, Palmer AA, de Wit H. Genetics of caffeine consumption and responses to caffeine. Psychopharmacology (Berl). 2010 Aug; 211(3):245-57. PMID: 20532872; PMCID: PMC4242593.
      Citations: 83     Fields:    Translation:HumansAnimals
    195. Vaughn LK, Denning G, Stuhr KL, de Wit H, Hill MN, Hillard CJ. Endocannabinoid signalling: has it got rhythm? Br J Pharmacol. 2010 Jun; 160(3):530-43. PMID: 20590563; PMCID: PMC2931554.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    196. Hamidovic A, Dlugos A, Palmer AA, de Wit H. Catechol-O-methyltransferase val158met genotype modulates sustained attention in both the drug-free state and in response to amphetamine. Psychiatr Genet. 2010 Jun; 20(3):85-92. PMID: 20414144; PMCID: PMC2875066.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    197. Lejuez CW, Magidson JF, Mitchell SH, Sinha R, Stevens MC, de Wit H. Behavioral and biological indicators of impulsivity in the development of alcohol use, problems, and disorders. Alcohol Clin Exp Res. 2010 Aug; 34(8):1334-45. PMID: 20491733; PMCID: PMC3182265.
      Citations: 133     Fields:    Translation:HumansAnimals
    198. Hamidovic A, Childs E, Conrad M, King A, de Wit H. Stress-induced changes in mood and cortisol release predict mood effects of amphetamine. Drug Alcohol Depend. 2010 Jun 01; 109(1-3):175-80. PMID: 20176450; PMCID: PMC2875349.
      Citations: 16     Fields:    Translation:Humans
    199. Childs E, Van Dam NT, de Wit H. Effects of acute progesterone administration upon responses to acute psychosocial stress in men. Exp Clin Psychopharmacol. 2010 Feb; 18(1):78-86. PMID: 20158297; PMCID: PMC4351805.
      Citations: 20     Fields:    Translation:Humans
    200. Hamidovic A, Dlugos A, Palmer AA, de Wit H. Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of D-amphetamine: an exploratory pharmacogenetic study using healthy volunteers. Behav Genet. 2010 Mar; 40(2):255-61. PMID: 20091113; PMCID: PMC4454285.
      Citations: 16     Fields:    Translation:Humans
    201. Childs E, Dlugos A, De Wit H. Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase. Psychophysiology. 2010 May 01; 47(3):550-9. PMID: 20070572; PMCID: PMC4242596.
      Citations: 49     Fields:    Translation:Humans
    202. Porcu P, O'Buckley TK, Alward SE, Song SC, Grant KA, de Wit H, Leslie Morrow A. Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans. Alcohol Clin Exp Res. 2010 Mar 01; 34(3):432-42. PMID: 20028362; PMCID: PMC2858248.
      Citations: 41     Fields:    Translation:HumansAnimals
    203. Hamidovic A, Dlugos A, Skol A, Palmer AA, de Wit H. Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants. Exp Clin Psychopharmacol. 2009 Dec; 17(6):374-83. PMID: 19968402; PMCID: PMC2879583.
      Citations: 53     Fields:    Translation:Humans
    204. Dlugos AM, Hamidovic A, Hodgkinson CA, Goldman D, Palmer AA, de Wit H. More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine. Neuropsychopharmacology. 2010 Feb; 35(3):613-22. PMID: 19890266; PMCID: PMC2945903.
      Citations: 17     Fields:    Translation:Humans
    205. Dlugos AM, Hamidovic A, Palmer AA, de Wit H. Further evidence of association between amphetamine response and SLC6A2 gene variants. Psychopharmacology (Berl). 2009 Oct; 206(3):501-11. PMID: 19727679; PMCID: PMC4242585.
      Citations: 12     Fields:    Translation:Humans
    206. Bedi G, Phan KL, Angstadt M, de Wit H. Effects of MDMA on sociability and neural response to social threat and social reward. Psychopharmacology (Berl). 2009 Nov; 207(1):73-83. PMID: 19680634; PMCID: PMC3328967.
      Citations: 84     Fields:    Translation:Humans
    207. Dlugos AM, Palmer AA, de Wit H. Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans. J Neural Transm (Vienna). 2009 Oct; 116(10):1323-34. PMID: 19657584; PMCID: PMC3653168.
      Citations: 21     Fields:    Translation:Humans
    208. Zacny JP, de Wit H. The prescription opioid, oxycodone, does not alter behavioral measures of impulsivity in healthy volunteers. Pharmacol Biochem Behav. 2009 Nov; 94(1):108-13. PMID: 19660489; PMCID: PMC2753749.
      Citations: 23     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    209. Metrik J, Rohsenow DJ, Monti PM, McGeary J, Cook TA, de Wit H, Haney M, Kahler CW. Effectiveness of a marijuana expectancy manipulation: Piloting the balanced-placebo design for marijuana. Exp Clin Psychopharmacol. 2009 Aug; 17(4):217-25. PMID: 19653787; PMCID: PMC2810847.
      Citations: 45     Fields:    Translation:Humans
    210. de Wit H, Shaham Y. Incentive motivation, conditioning, stress, and neuropsychiatric disorders: a tribute to Jane Stewart. Biol Psychiatry. 2009 May 15; 65(10):827-8. PMID: 19398047; PMCID: PMC2716031.
      Citations:    Fields:    
    211. Childs E, de Wit H. Amphetamine-induced place preference in humans. Biol Psychiatry. 2009 May 15; 65(10):900-4. PMID: 19111278; PMCID: PMC2693956.
      Citations: 50     Fields:    Translation:Humans
    212. Hamidovic A, de Wit H. Sleep deprivation increases cigarette smoking. Pharmacol Biochem Behav. 2009 Sep; 93(3):263-9. PMID: 19133287; PMCID: PMC2706278.
      Citations: 30     Fields:    Translation:Humans
    213. White TL, Lejuez CW, de Wit H. Test-retest characteristics of the Balloon Analogue Risk Task (BART). Exp Clin Psychopharmacol. 2008 Dec; 16(6):565-70. PMID: 19086777; PMCID: PMC4244869.
      Citations: 64     Fields:    Translation:Humans
    214. Childs E, de Wit H. Hormonal, cardiovascular, and subjective responses to acute stress in smokers. Psychopharmacology (Berl). 2009 Mar; 203(1):1-12. PMID: 18936915; PMCID: PMC2727744.
      Citations: 47     Fields:    Translation:Humans
    215. de Wit H. Impulsivity as a determinant and consequence of drug use: a review of underlying processes. Addict Biol. 2009 Jan; 14(1):22-31. PMID: 18855805; PMCID: PMC3640851.
      Citations: 593     Fields:    Translation:Humans
    216. Miczek KA, de Wit H. Challenges for translational psychopharmacology research--some basic principles. Psychopharmacology (Berl). 2008 Aug; 199(3):291-301. PMID: 18523737.
      Citations: 10     Fields:    Translation:HumansAnimals
    217. Acheson A, de Wit H. Bupropion improves attention but does not affect impulsive behavior in healthy young adults. Exp Clin Psychopharmacol. 2008 Apr; 16(2):113-23. PMID: 18489015; PMCID: PMC4270475.
      Citations: 49     Fields:    Translation:HumansCTClinical Trials
    218. Phan KL, Angstadt M, Golden J, Onyewuenyi I, Popovska A, de Wit H. Cannabinoid modulation of amygdala reactivity to social signals of threat in humans. J Neurosci. 2008 Mar 05; 28(10):2313-9. PMID: 18322078; PMCID: PMC2657360.
      Citations: 114     Fields:    Translation:Humans
    219. Childs E, Hohoff C, Xu K, Badner J, de Wit H, Deckert J. Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology. 2008 Nov; 33(12):2791-800. PMID: 18305461; PMCID: PMC2745641.
      Citations: 76     Fields:    Translation:Humans
    220. Hamidovic A, Kang UJ, de Wit H. Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers. J Clin Psychopharmacol. 2008 Feb; 28(1):45-51. PMID: 18204340.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    221. Childs E, de Wit H. Enhanced mood and psychomotor performance by a caffeine-containing energy capsule in fatigued individuals. Exp Clin Psychopharmacol. 2008 Feb; 16(1):13-21. PMID: 18266548.
      Citations: 23     Fields:    Translation:Humans
    222. White TL, Lejuez CW, de Wit H. Personality and gender differences in effects of d-amphetamine on risk taking. Exp Clin Psychopharmacol. 2007 Dec; 15(6):599-609. PMID: 18179313.
      Citations: 29     Fields:    Translation:Humans
    223. Acheson A, Richards JB, de Wit H. Effects of sleep deprivation on impulsive behaviors in men and women. Physiol Behav. 2007 Aug 15; 91(5):579-87. PMID: 17477941.
      Citations: 71     Fields:    Translation:Humans
    224. Freitag C, Hohoff C, McDonald J, Cook EH, de Wit H, Dlugos A, Deckert J. Norepinephrine transporter gene variation modulates acute response to D-amphetamine. Biol Psychiatry. 2007 Jun 01; 61(11):1296-305. PMID: 17239355.
      Citations: 25     Fields:    Translation:Humans
    225. Hariri AR, Brown SM, Williamson DE, Flory JD, de Wit H, Manuck SB. Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activity. J Neurosci. 2006 Dec 20; 26(51):13213-7. PMID: 17182771; PMCID: PMC6675016.
      Citations: 222     Fields:    Translation:Humans
    226. King A, de Wit H, Riley RC, Cao D, Niaura R, Hatsukami D. Efficacy of naltrexone in smoking cessation: a preliminary study and an examination of sex differences. Nicotine Tob Res. 2006 Oct; 8(5):671-82. PMID: 17008194.
      Citations: 44     Fields:    Translation:Humans
    227. Lott DC, Kim SJ, Cook EH, de Wit H. Serotonin transporter genotype and acute subjective response to amphetamine. Am J Addict. 2006 Sep-Oct; 15(5):327-35. PMID: 16966188.
      Citations: 19     Fields:    Translation:HumansCells
    228. White TL, Grover VK, de Wit H. Cortisol effects of D-amphetamine relate to traits of fearlessness and aggression but not anxiety in healthy humans. Pharmacol Biochem Behav. 2006 Sep; 85(1):123-31. PMID: 16934318.
      Citations: 9     Fields:    Translation:Humans
    229. de Wit H, Vicini L, Childs E, Sayla MA, Terner J. Does stress reactivity or response to amphetamine predict smoking progression in young adults? A preliminary study. Pharmacol Biochem Behav. 2007 Feb; 86(2):312-9. PMID: 16919319.
      Citations: 8     Fields:    Translation:Humans
    230. Acheson A, Farrar AM, Patak M, Hausknecht KA, Kieres AK, Choi S, de Wit H, Richards JB. Nucleus accumbens lesions decrease sensitivity to rapid changes in the delay to reinforcement. Behav Brain Res. 2006 Oct 16; 173(2):217-28. PMID: 16884790; PMCID: PMC4083481.
      Citations: 33     Fields:    Translation:Animals
    231. de Wit H, Vicini L, Haig GM, Hunt T, Feltner D. Evaluation of the abuse potential of pagoclone, a partial GABAA agonist. J Clin Psychopharmacol. 2006 Jun; 26(3):268-73. PMID: 16702891.
      Citations:    Fields:    Translation:Humans
    232. White TL, Lott DC, de Wit H. Personality and the subjective effects of acute amphetamine in healthy volunteers. Neuropsychopharmacology. 2006 May; 31(5):1064-74. PMID: 16237380.
      Citations: 31     Fields:    Translation:Humans
    233. Acheson A, Reynolds B, Richards JB, de Wit H. Diazepam impairs behavioral inhibition but not delay discounting or risk taking in healthy adults. Exp Clin Psychopharmacol. 2006 May; 14(2):190-8. PMID: 16756423.
      Citations: 18     Fields:    Translation:Humans
    234. Veenstra-VanderWeele J, Qaadir A, Palmer AA, Cook EH, de Wit H. Association between the casein kinase 1 epsilon gene region and subjective response to D-amphetamine. Neuropsychopharmacology. 2006 May; 31(5):1056-63. PMID: 16237383.
      Citations: 38     Fields:    Translation:HumansAnimals
    235. Acheson A, Mahler SV, Chi H, de Wit H. Differential effects of nicotine on alcohol consumption in men and women. Psychopharmacology (Berl). 2006 May; 186(1):54-63. PMID: 16565827.
      Citations: 48     Fields:    Translation:Humans
    236. Childs E, de Wit H. Subjective, behavioral, and physiological effects of acute caffeine in light, nondependent caffeine users. Psychopharmacology (Berl). 2006 May; 185(4):514-23. PMID: 16541243.
      Citations: 63     Fields:    Translation:Humans
    237. Reynolds B, Richards JB, de Wit H. Acute-alcohol effects on the Experiential Discounting Task (EDT) and a question-based measure of delay discounting. Pharmacol Biochem Behav. 2006 Feb; 83(2):194-202. PMID: 16516954.
      Citations: 88     Fields:    Translation:Humans
    238. Terner JM, de Wit H. Menstrual cycle phase and responses to drugs of abuse in humans. Drug Alcohol Depend. 2006 Sep 01; 84(1):1-13. PMID: 16413143.
      Citations: 96     Fields:    Translation:Humans
    239. Ramchandani VA, O'connor S, Neumark Y, Zimmermann US, Morzorati SL, de Wit H. The alcohol clamp: applications, challenges, and new directions--an RSA 2004 symposium summary. Alcohol Clin Exp Res. 2006 Jan; 30(1):155-64. PMID: 16433744.
      Citations: 27     Fields:    Translation:HumansAnimals
    240. King A, Munisamy G, de Wit H, Lin S. Attenuated cortisol response to alcohol in heavy social drinkers. Int J Psychophysiol. 2006 Mar; 59(3):203-9. PMID: 16359745.
      Citations: 49     Fields:    Translation:Humans
    241. Hohoff C, McDonald JM, Baune BT, Cook EH, de Wit H, Deckert J. Interindividual variation in anxiety response to amphetamine: possible role for adenosine A2A receptor gene variants. Am J Med Genet B Neuropsychiatr Genet. 2005 Nov 05; 139B(1):42-4. PMID: 16118787.
      Citations: 25     Fields:    Translation:Humans
    242. Holdstock L, Penland SN, Morrow AL, de Wit H. Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women. Psychopharmacology (Berl). 2006 Jun; 186(3):442-50. PMID: 16240164.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    243. Alsene KM, Mahler SV, de Wit H. Effects of d-amphetamine and smoking abstinence on cue-induced cigarette craving. Exp Clin Psychopharmacol. 2005 Aug; 13(3):209-18. PMID: 16173884.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    244. Lott DC, Kim SJ, Cook EH, de Wit H. Dopamine transporter gene associated with diminished subjective response to amphetamine. Neuropsychopharmacology. 2005 Mar; 30(3):602-9. PMID: 15602501.
      Citations: 51     Fields:    Translation:HumansCellsCTClinical Trials
    245. Mahler SV, de Wit H. Effects of haloperidol on reactions to smoking cues in humans. Behav Pharmacol. 2005 Mar; 16(2):123-6. PMID: 15767848.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    246. Young EM, Mahler S, Chi H, de Wit H. Mecamylamine and ethanol preference in healthy volunteers. Alcohol Clin Exp Res. 2005 Jan; 29(1):58-65. PMID: 15654292.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    247. Reynolds B, Richards JB, Dassinger M, de Wit H. Therapeutic doses of diazepam do not alter impulsive behavior in humans. Pharmacol Biochem Behav. 2004 Sep; 79(1):17-24. PMID: 15388279.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    248. Zernig G, De Wit H, Telser S, Nienhusmeier M, Wakonigg G, Sturm K, Berger I, Kemmler G, Saria A. Subjective effects of slow-release bupropion versus caffeine as determined in a quasi-naturalistic setting. Pharmacology. 2004 Apr; 70(4):206-15. PMID: 15001822.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    249. Fromme K, de Wit H, Hutchison KE, Ray L, Corbin WR, Cook TA, Wall TL, Goldman D. Biological and behavioral markers of alcohol sensitivity. Alcohol Clin Exp Res. 2004 Feb; 28(2):247-56. PMID: 15112932.
      Citations: 9     Fields:    Translation:HumansAnimals
    250. Kieres AK, Hausknecht KA, Farrar AM, Acheson A, de Wit H, Richards JB. Effects of morphine and naltrexone on impulsive decision making in rats. Psychopharmacology (Berl). 2004 Apr; 173(1-2):167-74. PMID: 14752586.
      Citations: 56     Fields:    Translation:Animals
    251. de Wit H, Richards JB. Dual determinants of drug use in humans: reward and impulsivity. Nebr Symp Motiv. 2004; 50:19-55. PMID: 15160637.
      Citations: 68     Fields:    Translation:Humans
    252. Farrar AM, Kieres AK, Hausknecht KA, de Wit H, Richards JB. Effects of reinforcer magnitude on an animal model of impulsive behavior. Behav Processes. 2003 Oct 31; 64(3):261-271. PMID: 14580697.
      Citations: 11     Fields:    
    253. de Wit H, Nikolayev L, Young E, Söderpalm AH. Effects of acute social stress on alcohol consumption in healthy subjects. Alcohol Clin Exp Res. 2003 Aug; 27(8):1270-7. PMID: 12966321.
      Citations: 48     Fields:    Translation:HumansCTClinical Trials
    254. Nikolayev L, de Wit H, Söderpalm A. Effects of stress on responses to methamphetamine in humans. Psychopharmacology (Berl). 2003 Nov; 170(2):188-99. PMID: 12845405.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    255. Alsene K, Sand P, de Wit H, Deckert J. Association between A2a receptor gene polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology. 2003 Sep; 28(9):1694-702. PMID: 12825092.
      Citations: 100     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    256. Chi H, de Wit H. Mecamylamine attenuates the subjective stimulant-like effects of alcohol in social drinkers. Alcohol Clin Exp Res. 2003 May; 27(5):780-6. PMID: 12766622.
      Citations: 50     Fields:    Translation:HumansCTClinical Trials
    257. McDonald J, Schleifer L, Richards JB, de Wit H. Effects of THC on behavioral measures of impulsivity in humans. Neuropsychopharmacology. 2003 Jul; 28(7):1356-65. PMID: 12784123.
      Citations: 150     Fields:    Translation:HumansCTClinical Trials
    258. Alsene KM, Li Y, Chaverneff F, de Wit H. Role of abstinence and visual cues on food and smoking craving. Behav Pharmacol. 2003 Mar; 14(2):145-51. PMID: 12658075.
      Citations: 7     Fields:    Translation:Humans
    259. Crean J, Richards JB, de Wit H, Crean J, Richards JB, de Wit H. Effect of tryptophan depletion on impulsive behavior in men with or without a family history of alcoholism. Behav Brain Res. 2002 Nov 15; 136(2):349-57. PMID: 12429396.
      Citations: 60     Fields:    Translation:HumansCTClinical Trials
    260. White TL, Justice AJ, de Wit H. Differential subjective effects of D-amphetamine by gender, hormone levels and menstrual cycle phase. Pharmacol Biochem Behav. 2002 Nov; 73(4):729-41. PMID: 12213517.
      Citations: 124     Fields:    Translation:HumansCTClinical Trials
    261. de Wit H, Enggasser JL, Richards JB, de Wit H, Enggasser JL, Richards JB. Acute administration of d-amphetamine decreases impulsivity in healthy volunteers. Neuropsychopharmacology. 2002 Nov; 27(5):813-25. PMID: 12431855.
      Citations: 193     Fields:    Translation:HumansCTClinical Trials
    262. Shaham Y, Shalev U, Lu L, de Wit H, Stewart J, Shaham Y, Shalev U, Lu L, de Wit H, Stewart J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl). 2003 Jul; 168(1-2):3-20. PMID: 12402102.
      Citations: 750     Fields:    Translation:HumansAnimalsPHPublic Health
    263. Reynolds B, de Wit H, Richards J, Reynolds B, de Wit H, Richards J. Delay of gratification and delay discounting in rats. Behav Processes. 2002 Sep 30; 59(3):157. PMID: 12270518.
      Citations: 26     Fields:    
    264. Wachtel SR, Ortengren A, de Wit H. The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers. Drug Alcohol Depend. 2002 Sep 01; 68(1):23-33. PMID: 12167550.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    265. King AC, Houle T, de Wit H, Holdstock L, Schuster A, King AC, Houle T, de Wit H, Holdstock L, Schuster A. Biphasic alcohol response differs in heavy versus light drinkers. Alcohol Clin Exp Res. 2002 Jun; 26(6):827-35. PMID: 12068251.
      Citations: 127     Fields:    Translation:HumansCTClinical Trials
    266. de Wit H, de Wit H. Effects of stress and alcohol on subjective state in humans. Alcohol Clin Exp Res. 2002 Jun; 26(6):818-26. PMID: 12068250.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    267. Wachtel SR, ElSohly MA, Ross SA, Ambre J, de Wit H, Wachtel SR, ElSohly MA, Ross SA, Ambre J, de Wit H. Comparison of the subjective effects of Delta(9)-tetrahydrocannabinol and marijuana in humans. Psychopharmacology (Berl). 2002 Jun; 161(4):331-9. PMID: 12073159.
      Citations: 86     Fields:    Translation:HumansAnimalsCTClinical Trials
    268. Cousins MS, Roberts DC, de Wit H, Cousins MS, Roberts DC, de Wit H. GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings. Drug Alcohol Depend. 2002 Feb 01; 65(3):209-20. PMID: 11841892.
      Citations: 76     Fields:    Translation:HumansAnimals
    269. Schleifer LA, Justice AJ, de Wit H. Lack of effects of acute estradiol on mood in postmenopausal women. Pharmacol Biochem Behav. 2002 Jan-Feb; 71(1-2):71-7. PMID: 11812509.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    270. Uftring SJ, Wachtel SR, Chu D, McCandless C, Levin DN, de Wit H. An fMRI study of the effect of amphetamine on brain activity. Neuropsychopharmacology. 2001 Dec; 25(6):925-35. PMID: 11750185.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    271. Enggasser JL, de Wit H. Haloperidol reduces stimulant and reinforcing effects of ethanol in social drinkers. Alcohol Clin Exp Res. 2001 Oct; 25(10):1448-56. PMID: 11696664.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    272. de Wit H, Schmitt L, Purdy R, Hauger R, de Wit H, Schmitt L, Purdy R, Hauger R. Effects of acute progesterone administration in healthy postmenopausal women and normally-cycling women. Psychoneuroendocrinology. 2001 Oct; 26(7):697-710. PMID: 11500251.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    273. Cousins MS, Stamat HM, de Wit H. Acute doses of d-amphetamine and bupropion increase cigarette smoking. Psychopharmacology (Berl). 2001 Sep; 157(3):243-53. PMID: 11605079.
      Citations: 47     Fields:    Translation:HumansCTClinical Trials
    274. Wachtel SR, de Wit H. Lack of effect of intravenous hydrocortisone on mood in humans: a preliminary study. Behav Pharmacol. 2001 Sep; 12(5):373-6. PMID: 11710752.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    275. Schuster A, de Wit H, Schuster A, de Wit H. Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. Pharmacol Biochem Behav. 2001 Jul-Aug; 69(3-4):343-50. PMID: 11509190.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    276. Cousins MS, Stamat HM, de Wit H, Cousins MS, Stamat HM, de Wit H. Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking. Nicotine Tob Res. 2001 May; 3(2):123-9. PMID: 11403726.
      Citations: 24     Fields:    Translation:HumansCTClinical Trials
    277. Holdstock L, de Wit H. Individual differences in responses to ethanol and d-amphetamine: a within-subject study. Alcohol Clin Exp Res. 2001 Apr; 25(4):540-8. PMID: 11329494.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    278. Wachtel SR, Charnot A, de Wit H. Acute hydrocortisone administration does not affect subjective responses to d-amphetamine in humans. Psychopharmacology (Berl). 2001 Jan; 153(3):380-8. PMID: 11271411.
      Citations: 5     Fields:    Translation:Humans
    279. de Wit H. Laboratory-based assessment of alcohol craving in social drinkers. Addiction. 2000 Aug; 95 Suppl 2:S165-9. PMID: 11002911.
      Citations: 25     Fields:    Translation:Humans
    280. de Wit H, Crean J, Richards JB. Effects of d-amphetamine and ethanol on a measure of behavioral inhibition in humans. Behav Neurosci. 2000 Aug; 114(4):830-7. PMID: 10959541.
      Citations: 110     Fields:    Translation:HumansCTClinical Trials
    281. Feola TW, de Wit H, Richards JB. Effects of d-amphetamine and alcohol on a measure of behavioral inhibition in rats. Behav Neurosci. 2000 Aug; 114(4):838-848. PMID: 10959542.
      Citations: 49     Fields:    Translation:Animals
    282. Holdstock L, de Wit H. Effects of ethanol at four phases of the menstrual cycle. Psychopharmacology (Berl). 2000 Jul; 150(4):374-82. PMID: 10958078.
      Citations: 30     Fields:    Translation:Humans
    283. Justice AJ, De Wit H. Acute effects of d-amphetamine during the early and late follicular phases of the menstrual cycle in women. Pharmacol Biochem Behav. 2000 Jul; 66(3):509-15. PMID: 10899363.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    284. Holdstock L, King AC, de Wit H. Subjective and objective responses to ethanol in moderate/heavy and light social drinkers. Alcohol Clin Exp Res. 2000 Jun; 24(6):789-94. PMID: 10888066.
      Citations: 81     Fields:    Translation:Humans
    285. Wachtel SR, de Wit H. Naltrexone does not block the subjective effects of oral Delta(9)-tetrahydrocannabinol in humans. Drug Alcohol Depend. 2000 Jun 01; 59(3):251-60. PMID: 10812285.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    286. Crean JP, de Wit H, Richards JB. Reward discounting as a measure of impulsive behavior in a psychiatric outpatient population. Exp Clin Psychopharmacol. 2000 May; 8(2):155-62. PMID: 10843297.
      Citations: 52     Fields:    Translation:HumansCTClinical Trials
    287. Justice AJ, de Wit H. Acute effects of estradiol pretreatment on the response to d-amphetamine in women. Neuroendocrinology. 2000 Jan; 71(1):51-9. PMID: 10644899.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    288. Kirk JM, de Wit H. Individual differences in the priming effect of ethanol in social drinkers. J Stud Alcohol. 2000 Jan; 61(1):64-71. PMID: 10627098.
      Citations: 19     Fields:    Translation:Humans
    289. Rukstalis M, de Wit H. Effects of triazolam at three phases of the menstrual cycle. J Clin Psychopharmacol. 1999 Oct; 19(5):450-8. PMID: 10505587.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    290. de Wit H, Svenson J, York A. Non-specific effect of naltrexone on ethanol consumption in social drinkers. Psychopharmacology (Berl). 1999 Sep 01; 146(1):33-41. PMID: 10485962.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    291. Justice AJ, de Wit H. Acute effects of d-amphetamine during the follicular and luteal phases of the menstrual cycle in women. Psychopharmacology (Berl). 1999 Jul; 145(1):67-75. PMID: 10445374.
      Citations: 88     Fields:    Translation:Humans
    292. Wachtel SR, de Wit H. Subjective and behavioral effects of repeated d-amphetamine in humans. Behav Pharmacol. 1999 May; 10(3):271-81. PMID: 10780242.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    293. Holdstock L, de Wit H. Individual differences in subjective responses to ethanol and triazolam. Behav Pharmacol. 1999 May; 10(3):283-95. PMID: 10780243.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    294. Kirk JM, de Wit H. Responses to oral delta9-tetrahydrocannabinol in frequent and infrequent marijuana users. Pharmacol Biochem Behav. 1999 May; 63(1):137-42. PMID: 10340534.
      Citations: 35     Fields:    Translation:Humans
    295. Holdstock L, de Wit H. Ethanol impairs saccadic and smooth pursuit eye movements without producing self-reports of sedation. Alcohol Clin Exp Res. 1999 Apr; 23(4):664-72. PMID: 10235302.
      Citations: 9     Fields:    Translation:Humans
    296. Richards JB, Zhang L, Mitchell SH, de Wit H. Delay or probability discounting in a model of impulsive behavior: effect of alcohol. J Exp Anal Behav. 1999 Mar; 71(2):121-43. PMID: 10220927; PMCID: PMC1284697.
      Citations: 257     Fields:    Translation:HumansCTClinical Trials
    297. Holdstock L, de Wit H. Individual differences in the biphasic effects of ethanol. Alcohol Clin Exp Res. 1998 Dec; 22(9):1903-11. PMID: 9884132.
      Citations: 44     Fields:    Translation:HumansCTClinical Trials
    298. de Wit H. Individual differences in acute effects of drugs in humans: their relevance to risk for abuse. NIDA Res Monogr. 1998 Mar; 169:176-87. PMID: 9686416.
      Citations: 9     Fields:    Translation:HumansAnimals
    299. Kirk JM, Doty P, De Wit H. Effects of expectancies on subjective responses to oral delta9-tetrahydrocannabinol. Pharmacol Biochem Behav. 1998 Feb; 59(2):287-93. PMID: 9476972.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    300. Cooper M, Metz J, de Wit H, Cook E, Lorenz J, Brown T. Interclass drug effects and changes in regional brain glucose metabolism. Psychopharmacol Bull. 1998; 34(2):229-32. PMID: 9641006.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    301. Doty P, Kirk JM, Cramblett MJ, de Wit H. Behavioral responses to ethanol in light and moderate social drinkers following naltrexone pretreatment. Drug Alcohol Depend. 1997 Aug 25; 47(2):109-16. PMID: 9298332.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    302. de Wit H, Clark M, Brauer LH. Effects of d-amphetamine in grouped versus isolated humans. Pharmacol Biochem Behav. 1997 May-Jun; 57(1-2):333-40. PMID: 9164591.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    303. Richards JB, Mitchell SH, de Wit H, Seiden LS. Determination of discount functions in rats with an adjusting-amount procedure. J Exp Anal Behav. 1997 May; 67(3):353-66. PMID: 9163939; PMCID: PMC1284611.
      Citations: 157     Fields:    Translation:Animals
    304. de Wit H, Rukstalis M. Acute effects of triazolam in women: relationships with progesterone, estradiol and allopregnanolone. Psychopharmacology (Berl). 1997 Mar; 130(1):69-78. PMID: 9089849.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    305. Zacny JP, Mitchell SH, Cramblett MJ, de Wit H. The effects of ethanol on the relative preference for cigarettes. Behav Pharmacol. 1997 Feb; 8(1):75-81. PMID: 9833003.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    306. Mitchell SH, Laurent CL, de Wit H. Interaction of expectancy and the pharmacological effects of d-amphetamine: subjective effects and self-administration. Psychopharmacology (Berl). 1996 Jun; 125(4):371-8. PMID: 8826542.
      Citations: 30     Fields:    Translation:HumansCTClinical Trials
    307. Brauer LH, Johanson CE, Schuster CR, Rothman RB, de Wit H. Evaluation of phentermine and fenfluramine, alone and in combination, in normal, healthy volunteers. Neuropsychopharmacology. 1996 Apr; 14(4):233-41. PMID: 8924191.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    308. Brauer LH, Ambre J, De Wit H. Acute tolerance to subjective but not cardiovascular effects of d-amphetamine in normal, healthy men. J Clin Psychopharmacol. 1996 Feb; 16(1):72-6. PMID: 8834422.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    309. Brauer LH, de Wit H. Subjective responses to d-amphetamine alone and after pimozide pretreatment in normal, healthy volunteers. Biol Psychiatry. 1996 Jan 01; 39(1):26-32. PMID: 8719123.
      Citations: 34     Fields:    Translation:HumansCTClinical Trials
    310. Brauer LH, Rukstalis MR, de Wit H. Acute subjective responses to paroxetine in normal volunteers. Drug Alcohol Depend. 1995 Oct; 39(3):223-30. PMID: 8556971.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    311. Mitchell SH, de Wit H, Zacny JP. Caffeine withdrawal symptoms and self-administration following caffeine deprivation. Pharmacol Biochem Behav. 1995 Aug; 51(4):941-5. PMID: 7675881.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    312. Mitchell SH, de Wit H, Zacny JP. Effects of varying ethanol dose on cigarette consumption in healthy normal volunteers. Behav Pharmacol. 1995 Jun; 6(4):359-365. PMID: 11224344.
      Citations: 36     Fields:    
    313. Doty P, de Wit H. Effects of naltrexone pretreatment on the subjective and performance effects of ethanol in social drinkers. Behav Pharmacol. 1995 Jun; 6(4):386-394. PMID: 11224347.
      Citations: 5     Fields:    
    314. Doty P, de Wit H. Effect of setting on the reinforcing and subjective effects of ethanol in social drinkers. Psychopharmacology (Berl). 1995 Mar; 118(1):19-27. PMID: 7597118.
      Citations: 41     Fields:    Translation:HumansCTClinical Trials
    315. de Wit H, Bodker B. Personality and drug preferences in normal volunteers. Int J Addict. 1994 Oct; 29(12):1617-30. PMID: 7836023.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    316. de Wit H, Doty P. Preference for ethanol and diazepam in light and moderate social drinkers: a within-subjects study. Psychopharmacology (Berl). 1994 Aug; 115(4):529-38. PMID: 7871098.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    317. Doty P, Zacny JP, de Wit H. Effects of ondansetron pretreatment on acute responses to ethanol in social drinkers. Behav Pharmacol. 1994 Aug; 5(4 And 5):461-469. PMID: 11224298.
      Citations: 6     Fields:    
    318. Brauer LH, Buican B, de Wit H. Effects of caffeine deprivation on taste and mood. Behav Pharmacol. 1994 Apr; 5(2):111-118. PMID: 11224258.
      Citations: 2     Fields:    
    319. Mitchell SH, de Wit H, Zacny JP. Effects of varying the "openness" of an economy on responding for cigarettes. Behav Pharmacol. 1994 Apr; 5(2):159-166. PMID: 11224264.
      Citations: 6     Fields:    
    320. Chutuape MA, de Wit H. Relationship between subjective effects and drug preferences: ethanol and diazepam. Drug Alcohol Depend. 1994 Feb; 34(3):243-51. PMID: 8033763.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    321. Dohrn CS, Lichtor JL, Coalson DW, Uitvlugt A, de Wit H, Zacny JP. Reinforcing effects of extended inhalation of nitrous oxide in humans. Drug Alcohol Depend. 1993 Feb; 31(3):265-80. PMID: 8462415.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    322. de Wit H, Dudish S, Ambre J. Subjective and behavioral effects of diazepam depend on its rate of onset. Psychopharmacology (Berl). 1993; 112(2-3):324-30. PMID: 7871037.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    323. Cole-Harding S, de Wit H. Self-administration of pentobarbital in light and moderate alcohol drinkers. Pharmacol Biochem Behav. 1992 Oct; 43(2):563-9. PMID: 1438493.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    324. Zacny JP, Lichtor JL, de Wit H. Subjective, behavioral, and physiologic responses to intravenous dezocine in healthy volunteers. Anesth Analg. 1992 Apr; 74(4):523-30. PMID: 1348168.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    325. Dohrn CS, Lichtor JL, Finn RS, Uitvlugt A, Coalson DW, Rupani G, de Wit H, Zacny JP. Subjective and psychomotor effects of nitrous oxide in healthy volunteers. Behav Pharmacol. 1992 Feb; 3(1):19-30. PMID: 11224098.
      Citations: 6     Fields:    
    326. de Wit H, Metz J, Cooper M. Studying psychoactive drugs with positron emission tomography: relationships between mood and metabolic rate. NIDA Res Monogr. 1992; 124:117-34. PMID: 1470208.
      Citations:    Fields:    Translation:Humans
    327. Zacny JP, Lichtor JL, Zaragoza JG, de Wit H. Effects of fasting on responses to intravenous fentanyl in healthy volunteers. J Subst Abuse. 1992; 4(2):197-207. PMID: 1504643.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    328. Zacny JP, Bodker BK, de Wit H. Effects of setting on the subjective and behavioral effects of d-amphetamine in humans. Addict Behav. 1992; 17(1):27-33. PMID: 1595423.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    329. Zacny JP, de Wit H. The effects of a restricted feeding regimen on cigarette smoking in humans. Addict Behav. 1992; 17(2):149-57. PMID: 1585842.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    330. Zacny JP, Lichtor JL, Zaragoza JG, de Wit H. Subjective and behavioral responses to intravenous fentanyl in healthy volunteers. Psychopharmacology (Berl). 1992; 107(2-3):319-26. PMID: 1615132.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    331. De Wit H. Preference procedures for testing the abuse liability of drugs in humans. Br J Addict. 1991 Dec; 86(12):1579-86. PMID: 1786490.
      Citations: 4     Fields:    Translation:Humans
    332. de Wit H. Diazepam preference in males with and without an alcoholic first-degree relative. Alcohol Clin Exp Res. 1991 Aug; 15(4):593-600. PMID: 1928632.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    333. de Wit H, Metz J, Wagner N, Cooper M. Effects of diazepam on cerebral metabolism and mood in normal volunteers. Neuropsychopharmacology. 1991 Aug; 5(1):33-41. PMID: 1930609.
      Citations: 1     Fields:    Translation:Humans
    334. Zacny JP, de Wit H. Effects of food deprivation on subjective effects and self-administration of marijuana in humans. Psychol Rep. 1991 Jun; 68(3 Pt 2):1263-74. PMID: 1924625.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    335. de Wit H, Griffiths RR. Testing the abuse liability of anxiolytic and hypnotic drugs in humans. Drug Alcohol Depend. 1991 Jun; 28(1):83-111. PMID: 1679388.
      Citations: 43     Fields:    Translation:Humans
    336. McCracken SG, de Wit H, Uhlenhuth EH, Johanson CE. Preference for diazepam in anxious adults. J Clin Psychopharmacol. 1990 Jun; 10(3):190-6. PMID: 2198297.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    337. de Wit H, Metz J, Wagner N, Cooper M. Behavioral and subjective effects of ethanol: relationship to cerebral metabolism using PET. Alcohol Clin Exp Res. 1990 Jun; 14(3):482-9. PMID: 2198826.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    338. Zacny JP, de Wit H. Effects of a 24-hour fast on cigarette smoking in humans. Br J Addict. 1990 Apr; 85(4):555-60. PMID: 2346795.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    339. de Wit H, McCracken SG. Ethanol self-administration in males with and without an alcoholic first-degree relative. Alcohol Clin Exp Res. 1990 Feb; 14(1):63-70. PMID: 2178475.
      Citations: 27     Fields:    Translation:Humans
    340. de Wit H, Metz J, Cooper M. Effects of ethanol, diazepam and amphetamines on cerebral metabolic rate: PET studies using FDG. NIDA Res Monogr. 1990; 105:61-7. PMID: 1876142.
      Citations:    Fields:    Translation:Humans
    341. Zacny JP, de Wit H. Effects of food deprivation on subjective responses to d-amphetamine in humans. Pharmacol Biochem Behav. 1989 Dec; 34(4):791-5. PMID: 2623032.
      Citations: 3     Fields:    Translation:Humans
    342. de Wit H, Metz J, Cooper M. The effects of 0.8 g.kg ethanol on cerebral metabolism and mood in normal volunteers. NIDA Res Monogr. 1989; 95:450. PMID: 2641027.
      Citations:    Fields:    Translation:Humans
    343. de Wit H, Pierri J, Johanson CE. Assessing pentobarbital preference in normal volunteers using a cumulative dosing procedure. Psychopharmacology (Berl). 1989; 99(3):416-21. PMID: 2594908.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    344. Zacny JP, de Wit H. Effects of food deprivation on responses to marijuana in humans. Behav Pharmacol. 1989; 1(2):177-185. PMID: 11175401.
      Citations: 1     Fields:    
    345. de Wit H, McCracken SM, Uhlenhuth EH, Johanson CE. Diazepam preference in subjects seeking treatment for anxiety. NIDA Res Monogr. 1987; 76:248-54. PMID: 3125453.
      Citations:    Fields:    Translation:Humans
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