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Jayant M. Pinto

TitleProfessor
InstitutionUniversity of Chicago
DepartmentSurgery-Ohns
AddressChicago IL 60637
Email
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    Collapse Overview 
    Collapse overview
    Dr. Pinto's research program has three major thematic goals:

    1) To understand the effect of aging on sinonasal and sensory disorders
    2) To determine how genetics, the environment, and social context (and their interaction) modulate susceptibility to these conditions
    3) To use this information to develop and test novel treatments for these and other common conditions of the ear, nose, and throat

    He utilizes tools from the fields of demography, genetic epidemiology, genomics, public health and sociology to accomplish these goals. Dr. Pinto's research is funded by the National Institute on Aging and the National Institute of Allergy and Infectious Disease.

    Research Projects:

    Epidemiology of Presbyosmia (Age-Related Olfactory Decline)
    We are exploiting data from the National Social Life, Health, and Aging Project (NSHAP) (led by Linda Waite in Sociology), to study the demographic and other non-genetic factors that are associated with olfactory decline in aging. We have identified race as a key factor that is independently associated with olfactory function and demonstrated that anosmia predicts five year all cause mortality in US adults, providing some the first nationally representative data on this condition. We are also examining the rich array of health and social measures available in NSHAP, including state of the art biomeasures to determine underlying biological mechanisms and environmental determinants. Additional members of the Olfactory Research Group (the ORG) include Martha McClintock in Psychology and William Dale in Geriatric and Palliative Medicine, along with statisticians Kristin Wroblewski and Philip Schumm in Public Health Studies.

    Genetics of Presbyosmia
    ?We are employing genome wide association studies in a founder population to identify genetic variation that underlies age-related olfactory loss using quantitative trait loci mapping in collaboration with Carole Ober in Human Genetics. We published the first successful linkage study for an olfactory trait in humans and are pursuing other collaborations (David Bennett, Rush University) to identify genetic contributions to this important disorder.

    Genetics of Chronic Rhinosinusitis
    We are performing state of the art genetic, epigenetic, and genomic studies of CRS as part of the Chronic Rhinosinusitis Integrated Studies Program, a U19 award from the National Institute of Allergy and Infectious Disease in collaboration with Northwestern University (Robert Schleimer) and Johns Hopkins University/Geisinger Health System (Brian Schwartz). The project at The University of Chicago, in partnership with Carole Ober, focuses on genetic variation in pathogen response. Our project is the only National Institutes of Health-funded project on the genetics of this disorder.

    The Upper Airway Microbiome
    We have shown that the microbial ecology in the middle meatus of the sinuses is altered in allergic subjects, potentially predisposing to disease. We have several ongoing investigations into how the sinonasal microbiome predicts physiological changes in both the upper and lower airway, as well as factors that affect its composition and function. Collaborating on these projects are Robert Naclerio and Fuad Baroody in OHNS, along with Carole Ober and Yoav Gilad in Human Genetics.

    Rhinology Clinical Trials and Translational Research
    The Nasal Physiology Laboratory, a joint endeavor with Robert Naclerio and Fuad Baroody, runs ongoing clinical trials and translational studies of conditions such as allergic and non-allergic rhinitis, chronic rhinosinusitis, nasal polyposis, and other common conditions. Call 773-702-5889 for details on our current projects.


    Collapse Biography 
    Collapse education and training
    University of Chicago, ILResearch FellowshipSection of OHNS, Department of Human Genetics, Section of Pulmonary/Critical Care Medicine
    University of Chicago, ILResidencySection of OHNS
    University of Chicago, ILInternshipDepartment of Surgery
    Stanford University School of Medicine, CAMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Hirsch AG, Nordberg C, Bandeen-Roche K, Tan BK, Schleimer RP, Kern RC, Sundaresan A, Pinto JM, Kennedy TL, Greene JS, Kuiper JR, Schwartz BS. Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample. Allergy. 2019 Nov 11. PMID: 31713250.
      View in: PubMed
    2. Siegel JK, Wroblewski KE, McClintock MK, Pinto JM. Olfactory dysfunction persists after smoking cessation and signals increased cardiovascular risk. Int Forum Allergy Rhinol. 2019 Sep; 9(9):977-985. PMID: 31365791.
      View in: PubMed
    3. Liu B, Luo Z, Pinto JM, Shiroma EJ, Tranah GJ, Wirdefeldt K, Fang F, Harris TB, Chen H. Relationship Between Poor Olfaction and Mortality Among Community-Dwelling Older Adults: A Cohort Study. Ann Intern Med. 2019 May 21; 170(10):673-681. PMID: 31035288.
      View in: PubMed
    4. Yao L, Yi X, Pinto JM, Yuan X, Guo Y, Liu Y, Wei Y. Olfactory cortex and Olfactory bulb volume alterations in patients with post-infectious Olfactory loss. Brain Imaging Behav. 2018 Oct; 12(5):1355-1362. PMID: 29234959.
      View in: PubMed
    5. Pinto JM, Baroody FM, Naclerio RM. Uncharted Waters: Challenges in the Era of Biologic Therapies for Nasal Polyposis. J Allergy Clin Immunol Pract. 2019 01; 7(1):68-70. PMID: 30217628.
      View in: PubMed
    6. Dale W, Kotwal AA, Shega JW, Schumm LP, Kern DW, Pinto JM, Pudelek KM, Waite LJ, McClintock MK. Cognitive Function and its Risk Factors Among Older US Adults Living at Home. Alzheimer Dis Assoc Disord. 2018 Jul-Sep; 32(3):207-213. PMID: 29334499.
      View in: PubMed
    7. Liu J, Pinto JM, Yang L, Yao L, Miao X, Wei Y. Evaluation of idiopathic olfactory loss with chemosensory event-related potentials and magnetic resonance imaging. Int Forum Allergy Rhinol. 2018 11; 8(11):1315-1322. PMID: 29782071.
      View in: PubMed
    8. Chiu BL, Pinto JM. Aging in the United States: Opportunities and Challenges for Otolaryngology-Head and Neck Surgery. Otolaryngol Clin North Am. 2018 Aug; 51(4):697-704. PMID: 29779618.
      View in: PubMed
    9. Sun ZF, Gao X, Pinto JM, He Y, Yang Q, Tian J, Lv QW, Wei YX. Morphological evaluation using MRI of the olfactory filaments (fila) in a post-traumatic olfactory rat model. World J Otorhinolaryngol Head Neck Surg. 2018 Mar; 4(1):50-56. PMID: 30035262.
      View in: PubMed
    10. Zhan X, Fang F, Wu C, Pinto JM, Wei Y. A Retrospective Study to Compare the Use of the Mean Apnea-Hypopnea Duration and the Apnea-Hypopnea Index with Blood Oxygenation and Sleep Patterns in Patients with Obstructive Sleep Apnea Diagnosed by Polysomnography. Med Sci Monit. 2018 Mar 31; 24:1887-1893. PMID: 29603712.
      View in: PubMed
    11. Zhong S, Pinto JM, Wroblewski KE, McClintock MK. Sensory Dysfunction and Sexuality in the U.S. Population of Older Adults. J Sex Med. 2018 04; 15(4):502-509. PMID: 29501426.
      View in: PubMed
    12. Soneru CP, Pinto JM. Patient and surgeon factors explain variation in the frequency of frontal sinus surgery. Laryngoscope. 2018 09; 128(9):2008-2014. PMID: 29417575.
      View in: PubMed
    13. Wu C, Wei YX, Pinto JM, Tian J, Yuan XD, Zhan XJ. [Effects of ginkgo biloba extract combined with glucocorticoid on olfactory function and inflammatory cytokines in mice with allergic rhinitis]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jan 20; 32(2):113-117. PMID: 29757557.
      View in: PubMed
    14. Naclerio RM, Baroody FM, Pinto JM. Nasal Polyps and Biomarkers. J Allergy Clin Immunol Pract. 2017 Nov - Dec; 5(6):1589-1590. PMID: 29122157.
      View in: PubMed
    15. Adams DR, Kern DW, Wroblewski KE, McClintock MK, Dale W, Pinto JM. Olfactory Dysfunction Predicts Subsequent Dementia in Older U.S. Adults. J Am Geriatr Soc. 2018 01; 66(1):140-144. PMID: 28944467.
      View in: PubMed
    16. Pinto JM, Wroblewski KE, Huisingh-Scheetz M, Correia C, Lopez KJ, Chen RC, Kern DW, Schumm PL, Dale W, McClintock MK. Global Sensory Impairment Predicts Morbidity and Mortality in Older U.S. Adults. J Am Geriatr Soc. 2017 Dec; 65(12):2587-2595. PMID: 28942611.
      View in: PubMed
    17. Lim S, Ramirez MV, Garneau JC, Ford MK, McKeough K, Ginat DT, Baroody FM, Armato SG, Pinto JM. Three-dimensional image analysis for staging chronic rhinosinusitis. Int Forum Allergy Rhinol. 2017 11; 7(11):1052-1057. PMID: 28941169.
      View in: PubMed
    18. Ajmani GS, Liederbach E, Kyrillos A, Wang CH, Pinto JM, Bhayani MK. Adjuvant radiation and survival following surgical resection of sinonasal melanoma. Am J Otolaryngol. 2017 Nov - Dec; 38(6):663-667. PMID: 28877859.
      View in: PubMed
    19. Dong J, Pinto JM, Guo X, Alonso A, Tranah G, Cauley JA, Garcia M, Satterfield S, Huang X, Harris T, Mosley TH, Chen H. The Prevalence of Anosmia and Associated Factors Among U.S. Black and White Older Adults. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1080-1086. PMID: 28498937.
      View in: PubMed
    20. McSorley VE, Pinto J, Schumm LP, Wroblewski K, Kern D, McClintock M, Lauderdale DS. Sleep and Olfaction among Older Adults. Neuroepidemiology. 2017; 48(3-4):147-154. PMID: 28743111.
      View in: PubMed
    21. Ajmani GS, Suh HH, Wroblewski KE, Pinto JM. Smoking and olfactory dysfunction: A systematic literature review and meta-analysis. Laryngoscope. 2017 08; 127(8):1753-1761. PMID: 28561327.
      View in: PubMed
    22. Hummel T, Whitcroft KL, Andrews P, Altundag A, Cinghi C, Costanzo RM, Damm M, Frasnelli J, Gudziol H, Gupta N, Haehne A, Holbrook E, Hong SC, Hornung D, Hüttenbrink KB, Kamel R, Kobayashi M, Konstantinidis I, Landis BN, Leopold DA, Macchi A, Miwa T, Moesges R, Mullol J, Mueller CA, Ottaviano G, Passali GC, Philpott C, Pinto JM, Ramakrishnan VJ, Rombaux P, Roth Y, Schlosser RA, Shu B, Soler G, Stjärne P, Stuck BA, Vodicka J, Welge-Luessen A. Position paper on olfactory dysfunction. Rhinol Suppl. 2017 03; 54(26):1-30. PMID: 29528615.
      View in: PubMed
    23. Adams DR, Wroblewski KE, Kern DW, Kozloski MJ, Dale W, McClintock MK, Pinto JM. Factors Associated with Inaccurate Self-Reporting of Olfactory Dysfunction in Older US Adults. Chem Senses. 2017 03 01; 42(3):223-231. PMID: 28007787.
      View in: PubMed
    24. Igartua C, Davenport ER, Gilad Y, Nicolae DL, Pinto J, Ober C. Host genetic variation in mucosal immunity pathways influences the upper airway microbiome. Microbiome. 2017 02 01; 5(1):16. PMID: 28143570.
      View in: PubMed
    25. Dong J, Wyss A, Yang J, Price TR, Nicolas A, Nalls M, Tranah G, Franceschini N, Xu Z, Schulte C, Alonso A, Cummings SR, Fornage M, Zaykin D, Li L, Huang X, Kritchevsky S, Liu Y, Gasser T, Wilson RS, De Jager PL, Singleton AB, Pinto JM, Harris T, Mosley TH, Bennett DA, London S, Yu L, Chen H. Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. Mol Neurobiol. 2017 Dec; 54(10):8021-8032. PMID: 27878761.
      View in: PubMed
    26. Pinto JM, Salvador R, Naclerio RM. Choice of Analgesics After Adenotonsillectomy: Are We Between a Rock and a Hard Place? JAMA Otolaryngol Head Neck Surg. 2016 11 01; 142(11):1041-1042. PMID: 27768163.
      View in: PubMed
    27. Ajmani GS, Wroblewski KE, Baroody FM, Naclerio RM, Pinto JM. Allergy and asthma medication use in home-dwelling U.S. older adults. Int Forum Allergy Rhinol. 2017 02; 7(2):192-198. PMID: 27696770.
      View in: PubMed
    28. Ajmani GS, Suh HH, Wroblewski KE, Kern DW, Schumm LP, McClintock MK, Yanosky JD, Pinto JM. Fine particulate matter exposure and olfactory dysfunction among urban-dwelling older US adults. Environ Res. 2016 Nov; 151:797-803. PMID: 27692900.
      View in: PubMed
    29. Adams DR, Ajmani GS, Pun VC, Wroblewski KE, Kern DW, Schumm LP, McClintock MK, Suh HH, Pinto JM. Nitrogen dioxide pollution exposure is associated with olfactory dysfunction in older U.S. adults. Int Forum Allergy Rhinol. 2016 12; 6(12):1245-1252. PMID: 27620703.
      View in: PubMed
    30. Olender T, Keydar I, Pinto JM, Tatarskyy P, Alkelai A, Chien MS, Fishilevich S, Restrepo D, Matsunami H, Gilad Y, Lancet D. The human olfactory transcriptome. BMC Genomics. 2016 08 11; 17(1):619. PMID: 27515280.
      View in: PubMed
    31. Tian J, Pinto JM, Cui X, Zhang H, Li L, Liu Y, Wu C, Wei Y. Sendai Virus Induces Persistent Olfactory Dysfunction in a Murine Model of PVOD via Effects on Apoptosis, Cell Proliferation, and Response to Odorants. PLoS One. 2016; 11(7):e0159033. PMID: 27428110.
      View in: PubMed
    32. Paz Lansberg M, DeTineo M, Lane J, Pinto JM, Baroody FM, Naclerio RM. A clinical trial of a microcrystalline cellulose topical nasal spray on the acute response to allergen challenge. Am J Rhinol Allergy. 2016 Jul; 30(4):269-73. PMID: 27456597.
      View in: PubMed
    33. Ajmani GS, Suh HH, Pinto JM. Effects of Ambient Air Pollution Exposure on Olfaction: A Review. Environ Health Perspect. 2016 Nov; 124(11):1683-1693. PMID: 27285588.
      View in: PubMed
    34. Wali E, Pinto JM, Cappaert M, Lambrix M, Blood AD, Blair EA, Small SD. Teaching professionalism in graduate medical education: What is the role of simulation? Surgery. 2016 09; 160(3):552-64. PMID: 27206333.
      View in: PubMed
    35. Liu J, Pinto JM, Yang L, Li L, Sun J, Miao X, Li K, Chen G, Wei Y. Gender difference in Chinese adults with post-viral olfactory disorder:a hospital-based study. Acta Otolaryngol. 2016 Sep; 136(9):976-81. PMID: 27118446.
      View in: PubMed
    36. Yang J, Pinto JM. The Epidemiology of Olfactory Disorders. Curr Otorhinolaryngol Rep. 2016 May; 4(2):130-141. PMID: 30613439.
      View in: PubMed
    37. Igartua C, Davenport ER, Chupp GL, Elias JA, Gilad Y, Ober C, Pinto JM. Nasal Microbiome Composition Is Associated with Chitotriosidase (Chit1) Activity in Adult Hutterites. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S100-1. PMID: 27027937.
      View in: PubMed
    38. Correia C, Lopez KJ, Wroblewski KE, Huisingh-Scheetz M, Kern DW, Chen RC, Schumm LP, Dale W, McClintock MK, Pinto JM. Global Sensory Impairment in Older Adults in the United States. J Am Geriatr Soc. 2016 Feb; 64(2):306-313. PMID: 26889840.
      View in: PubMed
    39. Hummel T, Whitcroft KL, Andrews P, Altundag A, Cinghi C, Costanzo RM, Damm M, Frasnelli J, Gudziol H, Gupta N, Haehner A, Holbrook E, Hong SC, Hornung D, Hüttenbrink KB, Kamel R, Kobayashi M, Konstantinidis I, Landis BN, Leopold DA, Macchi A, Miwa T, Moesges R, Mullol J, Mueller CA, Ottaviano G, Passali GC, Philpott C, Pinto JM, Ramakrishnan VJ, Rombaux P, Roth Y, Schlosser RA, Shu B, Soler G, Stjärne P, Stuck BA, Vodicka J, Welge-Luessen A. Position paper on olfactory dysfunction. Rhinology. 2016 Jan 31; 56(1):1-30. PMID: 28623665.
      View in: PubMed
    40. Sivam A, Wroblewski KE, Alkorta-Aranburu G, Barnes LL, Wilson RS, Bennett DA, Pinto JM. Olfactory Dysfunction in Older Adults is Associated with Feelings of Depression and Loneliness. Chem Senses. 2016 05; 41(4):293-9. PMID: 26809485.
      View in: PubMed
    41. Zhan X, Li L, Wang N, Ge X, Pinto JM, Wu X, Wei Y. Can upper airway surgery for OSA protect against cardiovascular sequelae via effects on coagulation? Acta Otolaryngol. 2016; 136(3):293-7. PMID: 26595664.
      View in: PubMed
    42. Dong J, Yang J, Tranah G, Franceschini N, Parimi N, Alkorta-Aranburu G, Xu Z, Alonso A, Cummings SR, Fornage M, Huang X, Kritchevsky S, Liu Y, London S, Niu L, Wilson RS, De Jager PL, Yu L, Singleton AB, Harris T, Mosley TH, Pinto JM, Bennett DA, Chen H. Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults. Medicine (Baltimore). 2015 Nov; 94(47):e1892. PMID: 26632684.
      View in: PubMed
    43. Pinto JM, Wroblewski KE, Kern DW, Schumm LP, McClintock MK. The Rate of Age-Related Olfactory Decline Among the General Population of Older U.S. Adults. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1435-41. PMID: 26253908.
      View in: PubMed
    44. Tian J, Pinto JM, Xin Y, Zhang H, Li L, Sun Z, Wei Y. Dexamethasone affects mouse olfactory mucosa gene expression and attenuates genes related to neurite outgrowth. Int Forum Allergy Rhinol. 2015 Oct; 5(10):907-18. PMID: 26140380.
      View in: PubMed
    45. Paz Silva M, Pinto JM, Corey JP, Mhoon EE, Baroody FM, Naclerio RM. Diagnostic algorithm for unilateral sinus disease: a 15-year retrospective review. Int Forum Allergy Rhinol. 2015 Jul; 5(7):590-6. PMID: 25880633.
      View in: PubMed
    46. Garneau J, Ramirez M, Armato SG, Sensakovic WF, Ford MK, Poon CS, Ginat DT, Starkey A, Baroody FM, Pinto JM. Computer-assisted staging of chronic rhinosinusitis correlates with symptoms. Int Forum Allergy Rhinol. 2015 Jul; 5(7):637-642. PMID: 25854318.
      View in: PubMed
    47. Kern DW, Schumm LP, Wroblewski KE, Pinto JM, Hummel T, McClintock MK. Olfactory thresholds of the U.S. Population of home-dwelling older adults: development and validation of a short, reliable measure. PLoS One. 2015; 10(3):e0118589. PMID: 25768291.
      View in: PubMed
    48. Mahdavinia M, Hsu J, Norton JE, Carter RG, Simon P, Siebert J, Cheatem L, Suh LA, Peters AT, Grammer LC, Kato A, Tan BK, Conley DB, Avila PC, Kern RC, Pinto JM, Ober C, Schleimer RP. Association of common filaggrin null mutations with atopy but not chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2015 May; 114(5):420-421. PMID: 25747786.
      View in: PubMed
    49. Li L, Zhan X, Wang N, Pinto JM, Ge X, Wang C, Tian J, Wei Y. Does airway surgery lower serum lipid levels in obstructive sleep apnea patients? A retrospective case review. Med Sci Monit. 2014 Dec 13; 20:2651-7. PMID: 25503376.
      View in: PubMed
    50. Yuan X, Fang J, Wang L, Yao L, Li L, Zhan X, Wu H, Pinto JM, Wei Y. Adequate continuous positive airway pressure therapy reduces mortality in Chinese patients with obstructive sleep apnea. Sleep Breath. 2015 Sep; 19(3):911-20. PMID: 25487312.
      View in: PubMed
    51. Kern DW, Wroblewski KE, Schumm LP, Pinto JM, Chen RC, McClintock MK. Olfactory function in Wave 2 of the National Social Life, Health, and Aging Project. J Gerontol B Psychol Sci Soc Sci. 2014 Nov; 69 Suppl 2:S134-43. PMID: 25360014.
      View in: PubMed
    52. Pinto JM, Kern DW, Wroblewski KE, Chen RC, Schumm LP, McClintock MK. Sensory function: insights from Wave 2 of the National Social Life, Health, and Aging Project. J Gerontol B Psychol Sci Soc Sci. 2014 Nov; 69 Suppl 2:S144-53. PMID: 25360015.
      View in: PubMed
    53. Pinto JM, Wroblewski KE, Kern DW, Schumm LP, McClintock MK. Olfactory dysfunction predicts 5-year mortality in older adults. PLoS One. 2014; 9(10):e107541. PMID: 25271633.
      View in: PubMed
    54. Kern DW, Wroblewski KE, Schumm LP, Pinto JM, McClintock MK. Field Survey Measures of Olfaction: The Olfactory Function Field Exam (OFFE). Field methods. 2014 Nov; 26(4):421-434. PMID: 27226782.
      View in: PubMed
    55. Yao L, Pinto JM, Yi X, Li L, Peng P, Wei Y. Gray matter volume reduction of olfactory cortices in patients with idiopathic olfactory loss. Chem Senses. 2014 Nov; 39(9):755-60. PMID: 25240014.
      View in: PubMed
    56. Naclerio RM, Pinto JM, Baroody FM. Drowning in applications for residency training: a program's perspective and simple solutions. JAMA Otolaryngol Head Neck Surg. 2014 Aug; 140(8):695-6. PMID: 24993023.
      View in: PubMed
    57. Choi CH, Poroyko V, Watanabe S, Jiang D, Lane J, deTineo M, Baroody FM, Naclerio RM, Pinto JM. Seasonal allergic rhinitis affects sinonasal microbiota. Am J Rhinol Allergy. 2014 Jul-Aug; 28(4):281-6. PMID: 25197913.
      View in: PubMed
    58. Fu D, Pinto JM, Wang L, Chen G, Zhan X, Wei Y. The effect of nasal structure on olfactory function in patients with OSA. Eur Arch Otorhinolaryngol. 2015 Feb; 272(2):357-62. PMID: 24890976.
      View in: PubMed
    59. Watanabe S, Pinto JM, Bashir ME, De Tineo M, Suzaki H, Baroody FM, Naclerio RM, Sharma S. Effect of prednisone on nasal symptoms and peripheral blood T-cell function in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2014 Aug; 4(8):609-16. PMID: 24753507.
      View in: PubMed
    60. Naclerio RM, Pinto J, Baroody F. Evidence-based approach to medical and surgical treatment of nasal polyposis. J Allergy Clin Immunol. 2013 Dec; 132(6):1461-1462.e3. PMID: 24286725.
      View in: PubMed
    61. Patel RM, Pinto JM. Olfaction: anatomy, physiology, and disease. Clin Anat. 2014 Jan; 27(1):54-60. PMID: 24272785.
      View in: PubMed
    62. Pinto JM, Schumm LP, Wroblewski KE, Kern DW, McClintock MK. Racial disparities in olfactory loss among older adults in the United States. J Gerontol A Biol Sci Med Sci. 2014 Mar; 69(3):323-9. PMID: 23689829.
      View in: PubMed
    63. Naclerio RM, Baroody FM, Pinto JM. Should clinicians use omalizumab for the treatment of nasal polyps? J Allergy Clin Immunol. 2013 Jul; 132(1):247. PMID: 23684073.
      View in: PubMed
    64. Hsu J, Avila PC, Kern RC, Hayes MG, Schleimer RP, Pinto JM. Genetics of chronic rhinosinusitis: state of the field and directions forward. J Allergy Clin Immunol. 2013 Apr; 131(4):977-93, 993.e1-5. PMID: 23540616.
      View in: PubMed
    65. Keydar I, Ben-Asher E, Feldmesser E, Nativ N, Oshimoto A, Restrepo D, Matsunami H, Chien MS, Pinto JM, Gilad Y, Olender T, Lancet D. General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations. Hum Mutat. 2013 Jan; 34(1):32-41. PMID: 22936402.
      View in: PubMed
    66. Sharma S, Watanabe S, Sivam A, Wang J, Neuwirth SJ, Perez RI, De Tineo M, Baroody FM, Naclerio RM, Pinto JM. Peripheral blood and tissue T regulatory cells in chronic rhinosinusitis. Am J Rhinol Allergy. 2012 Sep-Oct; 26(5):371-9. PMID: 23168151.
      View in: PubMed
    67. Andrews JD, Nocon CC, Small SM, Pinto JM, Blair EA. Emergency airway management: training and experience of chief residents in otolaryngology and anesthesiology. Head Neck. 2012 Dec; 34(12):1720-6. PMID: 22287361.
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    68. Song JE, Tanaka SM, Pinto JM, Rasmussen B, Ferro LM, Saadia-Redleaf MI. Long-term effects of hearing aids on word recognition scores. Ann Otol Rhinol Laryngol. 2011 May; 120(5):314-9. PMID: 21675587.
      View in: PubMed
    69. Pinto JM. Olfaction. Proc Am Thorac Soc. 2011 Mar; 8(1):46-52. PMID: 21364221.
      View in: PubMed
    70. Sharma S, Vasnani R, De Tineo M, Du G, Pinto JM, Baroody FM, Naclerio RM. Recruitment factors which affect the outcome of a seasonal allergic rhinitis trial. Allergy Asthma Proc. 2011 Jan-Feb; 32(1):55-63. PMID: 21262099.
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    71. Marcet MM, Setabutr P, Lemke BN, Collins ME, Fleming JC, Wesley RE, Pinto JM, Putterman AM. Surgical microanatomy of the müller muscle-conjunctival resection ptosis procedure. Ophthalmic Plast Reconstr Surg. 2010 Sep-Oct; 26(5):360-4. PMID: 20622700.
      View in: PubMed
    72. Pinto JM, Mehta N, DiTineo M, Wang J, Baroody FM, Naclerio RM. A randomized, double-blind, placebo-controlled trial of anti-IgE for chronic rhinosinusitis. Rhinology. 2010 Sep; 48(3):318-24. PMID: 21038023.
      View in: PubMed
    73. Sivam A, Jeswani S, Reder L, Wang J, DeTineo M, Taxy J, Baroody FM, Naclerio RM, Pinto JM. Olfactory cleft inflammation is present in seasonal allergic rhinitis and is reduced with intranasal steroids. Am J Rhinol Allergy. 2010 Jul-Aug; 24(4):286-90. PMID: 20819468.
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    74. Pinto JM, Jeswani S. Rhinitis in the geriatric population. Allergy Asthma Clin Immunol. 2010 May 13; 6(1):10. PMID: 20465792.
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    75. Thompson EE, Haller G, Pinto JM, Sun Y, Zelano B, Jacob S, McClintock MK, Nicolae DL, Ober C. Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors. Hum Immunol. 2010 Jan; 71(1):100-3. PMID: 19833159.
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    76. Chun RH, Pinto JM, Blankenhorn R, Dayal VS. Recovery of otoacoustic emission function in luetic endolymphatic hydrops: a possible measure of improvement in cochlear function. Int J Otolaryngol. 2009; 2009:942096. PMID: 20111587.
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    77. Pinto JM, Hayes MG, Schneider D, Naclerio RM, Ober C. A genomewide screen for chronic rhinosinusitis genes identifies a locus on chromosome 7q. Laryngoscope. 2008 Nov; 118(11):2067-72. PMID: 18622306.
      View in: PubMed
    78. Baroody FM, Pinto JM, Naclerio RM. Otolaryngology (urban) legend: the more programs to which you apply, the better the chances of matching. Arch Otolaryngol Head Neck Surg. 2008 Oct; 134(10):1038. PMID: 18936346.
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    79. Sahin-Yilmaz A, Baroody FM, DeTineo M, Cuttance G, Makinson D, Pinto JM, Naureckas ET, Naclerio RM. Effect of changing airway pressure on the ability of the human nose to warm and humidify air. Ann Otol Rhinol Laryngol. 2008 Jul; 117(7):501-5. PMID: 18700424.
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    80. Pinto JM, Schneider J, Perez R, DeTineo M, Baroody FM, Naclerio RM. Serum 25-hydroxyvitamin D levels are lower in urban African American subjects with chronic rhinosinusitis. J Allergy Clin Immunol. 2008 Aug; 122(2):415-7. PMID: 18585770.
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    81. Redleaf MI, Pinto JM, Klemens JJ. Imaging case study: enlarged superior vestibular nerve canal with sensorineural hearing loss. J Laryngol Otol. 2009 May; 123(5):572-4. PMID: 18501037.
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    82. Pinto JM, Thanaviratananich S, Hayes MG, Naclerio RM, Ober C. A genome-wide screen for hyposmia susceptibility Loci. Chem Senses. 2008 Apr; 33(4):319-29. PMID: 18245794.
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    83. Naclerio RM, Pinto J, deTineo M, Baroody FM. Elucidating the mechanism underlying the ocular symptoms associated with allergic rhinitis. Allergy Asthma Proc. 2008 Jan-Feb; 29(1):24-8. PMID: 18302834.
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    84. Sahin-Yilmaz A, Pinto JM, de Tineo M, Elwany S, Naclerio RM. Familial aggregation of nasal conditioning capacity. J Appl Physiol (1985). 2007 Sep; 103(3):1078-81. PMID: 17641214.
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    85. Naclerio RM, Pinto J, Assanasen P, Baroody FM. Observations on the ability of the nose to warm and humidify inspired air. Rhinology. 2007 Jun; 45(2):102-11. PMID: 17708456.
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    86. Mucha SM, Song DH, Pinto JM. Delayed maxillary sinusitis after orbital floor repair. Otolaryngol Head Neck Surg. 2007 Mar; 136(3):508-9. PMID: 17321894.
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    87. Zhang X, De la Cruz O, Pinto JM, Nicolae D, Firestein S, Gilad Y. Characterizing the expression of the human olfactory receptor gene family using a novel DNA microarray. Genome Biol. 2007; 8(5):R86. PMID: 17509148.
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    88. Sigari F, Schneider J, Pinto JM. Use of a mobile operative unit for in-patient otolaryngology procedures. Otolaryngol Head Neck Surg. 2007 Jan; 136(1):125-7. PMID: 17210347.
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    89. Pinto JM, Naclerio RM. Environmental and allergic factors in chronic rhinosinusitis. Clin Allergy Immunol. 2007; 20:25-49. PMID: 17534044.
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    90. Pinto JM, Elwany S, Baroody FM, Naclerio RM. Effects of saline sprays on symptoms after endoscopic sinus surgery. Am J Rhinol. 2006 Mar-Apr; 20(2):191-6. PMID: 16686387.
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    91. Shilling RA, Pinto JM, Decker DC, Schneider DH, Bandukwala HS, Schneider JR, Camoretti-Mercado B, Ober C, Sperling AI. Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production. J Immunol. 2005 Aug 15; 175(4):2061-5. PMID: 16081771.
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    92. Pinto JM, Assanasen P, Baroody FM, Naureckas E, Naclerio RM. Alpha-adrenoreceptor blockade with phenoxybenzamine does not affect the ability of the nose to condition air. J Appl Physiol (1985). 2005 Jul; 99(1):128-33. PMID: 15746297.
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    93. Pinto JM, Assanasen P, Baroody FM, Naureckas E, Solway J, Naclerio RM. Treatment of nasal inflammation decreases the ability of subjects with asthma to condition inspired air. Am J Respir Crit Care Med. 2004 Oct 15; 170(8):863-9. PMID: 15172894.
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    94. Pinto JM, Baroody FM. Chronic sinusitis and allergic rhinitis: at the nexus of sinonasal inflammatory disease. J Otolaryngol. 2002 Aug; 31 Suppl 1:S10-7. PMID: 12243237.
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    95. Pinto JM, Ansley J, Baroody FM. Lack of utility of postoperative chest radiograph in pediatric tracheotomy. Otolaryngol Head Neck Surg. 2001 Sep; 125(3):241-4. PMID: 11555760.
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    96. López-Beret P, Pinto JM, Romero A, Orgaz A, Fontcuberta J, Oblas M. Systematic study of occult pulmonary thromboembolism in patients with deep venous thrombosis. J Vasc Surg. 2001 Mar; 33(3):515-21. PMID: 11241121.
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    97. Céspedes M, Saez A, Rodríguez I, Pinto JM, Rodríguez R. Chronic anisakiasis presenting as a mesenteric mass. Abdom Imaging. 2000 Sep-Oct; 25(5):548-50. PMID: 10931996.
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    98. Pinto JM, Boyden PA. Electrical remodeling in ischemia and infarction. Cardiovasc Res. 1999 May; 42(2):284-97. PMID: 10533567.
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    99. Pinto JM, Boyden PA. Reduced inward rectifying and increased E-4031-sensitive K+ current density in arrhythmogenic subendocardial purkinje myocytes from the infarcted heart. J Cardiovasc Electrophysiol. 1998 Mar; 9(3):299-311. PMID: 9554735.
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    100. Kirby DA, Pinto JM, Weiss JW, Garpestad E, Zinkovska S. Effects of beta adrenergic receptor blockade on hemodynamic changes associated with obstructive sleep apnea. Physiol Behav. 1995 Nov; 58(5):919-23. PMID: 8577888.
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    101. Boyden PA, Pinto JM. Reduced calcium currents in subendocardial Purkinje myocytes that survive in the 24- and 48-hour infarcted heart. Circulation. 1994 Jun; 89(6):2747-59. PMID: 8205689.
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    102. Zhao S, Pinto JM, Bergau D, Lown B, Kirby DA. Plasma norepinephrine changes after arousal and exercise were enhanced in conscious pigs with perinephritic hypertension. Am J Hypertens. 1993 Oct; 6(10):844-50. PMID: 8267940.
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    103. Pinto JM, Garpestad E, Weiss JW, Bergau DM, Kirby DA. Hemodynamic changes associated with obstructive sleep apnea followed by arousal in a porcine model. J Appl Physiol (1985). 1993 Oct; 75(4):1439-43. PMID: 8282587.
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    104. Pinto JM, Lown B, Fujii AM, Kirby DA. Transient coronary stenosis associated with arrhythmia and ischemia 24 hours after reperfusion. Am Heart J. 1992 Sep; 124(3):565-70. PMID: 1381141.
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    105. Johnson DA, Pinto JM, Kirby DA, Lown B. Catecholamines in cerebrospinal fluid are increased by behavioral arousal and myocardial ischemia. Am J Physiol. 1992 Jul; 263(1 Pt 2):H83-7. PMID: 1636775.
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    106. Kirby DA, Pinto JM, Hottinger S, Johnson DA, Lown B. Behavioral arousal enhances inducibility and rate of ventricular tachycardia. Am J Physiol. 1991 Dec; 261(6 Pt 2):H1734-9. PMID: 1661087.
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    107. Pinto JM, Kirby DA, Lown B. Decrease in repetitive extrasystole threshold during epinephrine infusion is enhanced in conscious dogs with perinephritic hypertension. Physiol Behav. 1991 Feb; 49(2):383-6. PMID: 1712113.
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    108. Pinto JM, Kirby DA, Maher TJ, Lown B. Decreases in repetitive extrasystole threshold in the conscious pig with myocardial infarct were reversed by tyrosine. Life Sci. 1991; 49(6):419-26. PMID: 1714030.
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    109. Pinto JM, Kirby DA, Johnson DA, Lown B. Diazepam administered prior to coronary artery occlusion increases latency to ventricular fibrillation. Life Sci. 1991; 49(8):587-94. PMID: 1865752.
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    110. Kirby DA, Pinto JM, Lown B. Changes in ventricular fibrillation threshold during the development of perinephritic hypertension. Am J Hypertens. 1990 Oct; 3(10):741-8. PMID: 2145866.
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    111. Pinto JM, Kirby DA, Lown B. Epinephrine-induced decrease in repetitive extrasystole threshold is reversed by tyrosine in conscious dogs. Life Sci. 1990; 47(11):917-23. PMID: 1699105.
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    112. Pinto JM, Kirby DA, Verrier RL. Abolition of clonidine's effects on ventricular refractoriness by naloxone in the conscious dog. Life Sci. 1989; 45(5):413-20. PMID: 2770406.
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    113. Desai PB, Vyas JJ, Sharma S, Advani SH, Gopal R, Saikia TK, Dinshaw KA, Pinto JM, Swaroop VS. The impact of combined therapeutic modalities in head, neck, and esophageal cancer. Semin Surg Oncol. 1985; 1(3):116-31. PMID: 2414837.
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    114. Gohokar D, Pai VR, Kurkure PA, Pinto JM, Shetty PA. Ewing's sarcoma--5 years experience with chemotherapy. Indian J Cancer. 1984 Nov-1985 Jan; 21(5-6):203-6. PMID: 6545235.
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    115. Dinshaw KA, Pinto JM. Current status of lymphography in the management of lymphomas. Indian J Cancer. 1977 Sep; 14(3):256-61. PMID: 924508.
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    116. Sharma OP, Pinto JM, Hingorani CB. Chondrosarcoma--a roentgenographic and follow-up study. Indian J Cancer. 1974 Sep; 11(3):326-35. PMID: 4442924.
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