Anti-PD1 prolongs the response of PI3K and farnesyl transferase inhibition in HRAS- and PIK3CA-mutant head and neck cancers.

Anti-PD1 prolongs the response of PI3K and farnesyl transferase inhibition in HRAS- and PIK3CA-mutant head and neck cancers. Neoplasia. 2025 05; 63:101157.

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subject areas

Animals
CD8-Positive T-Lymphocytes
Cell Line, Tumor
Class I Phosphatidylinositol 3-Kinases
Disease Models, Animal
Farnesyltranstransferase
Female
Head and Neck Neoplasms
Humans
Mice
Mutation
Programmed Cell Death 1 Receptor
Proto-Oncogene Proteins p21(ras)
Quinolones
Signal Transduction
Thiazoles
Xenograft Model Antitumor Assays

authors with profiles

Ari Rosenberg