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Kelly Hynes

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentOrthopedic Surgery and Rehabilitation Medicine
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Kelly Hynes specializes in the diagnosis and treatment of all Orthopaedic foot and ankle conditions, including trauma, sports injuries (including foot and ankle arthroscopy), forefoot deformity (such as bunions) and degenerative disease (including total ankle arthroplasty). She provides skilled, compassionate care to treat pain and restore function for a broad range of common and complex foot and ankle disorders.

    Dr. Hynes has an interest in health care delivery and biomedical informatics. She is the Ambulatory Medical Director for the department of Orthopaedic Surgery and Rehabilitation Medicine as well as a Medical Director of Informatics for UChicago Medicine. She is also committed to the education of future generations of Orthopaedic surgeons and teaches at regional and international courses.


    Collapse Biography 
    Collapse education and training
    University of British ColumbiaFellowship
    University of OttawaResidency
    Memorial University of Newfoundland and LabradorMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Polachek WS, Baker HP, Dahm JS, Strelzow JA, Hynes KK. Diabetic Kidney Disease Is Associated With Increased Complications Following Operative Management of Ankle Fractures. Foot Ankle Orthop. 2022 Jul; 7(3):24730114221112106. PMID: 35898793.
      View in: PubMed
    2. Baker HP, Portney DA, Schroedl LM, Strelzow JA, Hynes K, Dillman DB. The Effect of Fascia Iliaca Compartment Blockade on Mortality in Patients With Hip Fractures: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Am Acad Orthop Surg. 2022 Feb 01; 30(3):e384-e394. PMID: 35772091.
      View in: PubMed
    3. Polachek WS, Baker HP, Dahm JS, Strelzow J, Hynes KK. Diabetic Kidney Disease is Associated with Increased Complications Following Operative Management of Ankle Fractures. Foot Ankle Orthop. 2022 Jan; 7(1):2473011421S00399. PMID: 35097886.
      View in: PubMed
    4. Polachek WS, Lee C, Scott BL, Hynes KK. Preoperative Opioid Prescription is a Risk Factor for Extended Opioid Filling After Ankle Arthroscopy. Foot Ankle Orthop. 2022 Jan; 7(1):2473011421S00400. PMID: 35097887.
      View in: PubMed
    5. Zhao X, Huang B, Wang H, Ni N, He F, Liu Q, Shi D, Chen C, Zhao P, Wang X, Wagstaff W, Pakvasa M, Tucker AB, Lee MJ, Wolf JM, Reid RR, Hynes K, Strelzow J, Ho SH, Yu T, Yang J, Shen L, He TC, Zhang Y. A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs). Am J Transl Res. 2021; 13(5):4233-4250. PMID: 34150011.
      View in: PubMed
    6. Zhao X, Hu DA, Wu D, He F, Wang H, Huang L, Shi D, Liu Q, Ni N, Pakvasa M, Zhang Y, Fu K, Qin KH, Li AJ, Hagag O, Wang EJ, Sabharwal M, Wagstaff W, Reid RR, Lee MJ, Wolf JM, El Dafrawy M, Hynes K, Strelzow J, Ho SH, He TC, Athiviraham A. Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering. Front Bioeng Biotechnol. 2021; 9:603444. PMID: 33842441.
      View in: PubMed
    7. Zhang Y, Wu D, Zhao X, Pakvasa M, Tucker AB, Luo H, Qin KH, Hu DA, Wang EJ, Li AJ, Zhang M, Mao Y, Sabharwal M, He F, Niu C, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Chen C, Wagstaff W, Reid RR, Athiviraham A, Ho S, Lee MJ, Hynes K, Strelzow J, He TC, El Dafrawy M. Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine. Front Bioeng Biotechnol. 2020; 8:598607. PMID: 33381499.
      View in: PubMed
    8. He F, Ni N, Zeng Z, Wu D, Feng Y, Li AJ, Luu B, Li AF, Qin K, Wang E, Wang X, Wu X, Luo H, Zhang J, Zhang M, Mao Y, Pakvasa M, Wagstaff W, Zhang Y, Niu C, Wang H, Huang L, Shi D, Liu Q, Zhao X, Fu K, Reid RR, Wolf JM, Lee MJ, Hynes K, Strelzow J, El Dafrawy M, Gan H, He TC, Fan J. FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells. Mol Ther Nucleic Acids. 2020 Dec 04; 22:885-899. PMID: 33230483.
      View in: PubMed
    9. Rizzi AM, Polachek WS, Dulas M, Strelzow JA, Hynes KK. The new 'normal': Rapid adoption of telemedicine in orthopaedics during the COVID-19 pandemic. Injury. 2020 Dec; 51(12):2816-2821. PMID: 32951916.
      View in: PubMed
    10. Wang X, Zhao L, Wu X, Luo H, Wu D, Zhang M, Zhang J, Pakvasa M, Wagstaff W, He F, Mao Y, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Hynes K, Strelzow J, El Dafrawy M, He TC, Qi H, Zeng Z. Development of a simplified and inexpensive RNA depletion method for plasmid DNA purification using size selection magnetic beads (SSMBs). Genes Dis. 2021 May; 8(3):298-306. PMID: 33997177.
      View in: PubMed
    11. Pakvasa M, Haravu P, Boachie-Mensah M, Jones A, Coalson E, Liao J, Zeng Z, Wu D, Qin K, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Lee MJ, Wolf JM, Athiviraham A, Ho SS, He TC, Hynes K, Strelzow J, El Dafrawy M, Reid RR. Notch signaling: Its essential roles in bone and craniofacial development. Genes Dis. 2021 Jan; 8(1):8-24. PMID: 33569510.
      View in: PubMed
    12. Zhang B, Yang L, Zeng Z, Feng Y, Wang X, Wu X, Luo H, Zhang J, Zhang M, Pakvasa M, Wagstaff W, He F, Mao Y, Qin K, Ding H, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Athiviraham A, Moriatis Wolf J, Lee MJ, Hynes K, Strelzow J, El Dafrawy M, Xia Y, He TC. Leptin Potentiates BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Through the Activation of JAK/STAT Signaling. Stem Cells Dev. 2020 04 15; 29(8):498-510. PMID: 32041483.
      View in: PubMed
    13. Lee CS, Divi SN, Dirschl DR, Hynes KK. Financial Impact of Magnetic Resonance Imaging in the Surgical Treatment of Foot and Ankle Osteomyelitis. J Foot Ankle Surg. 2020 Jan - Feb; 59(1):69-74. PMID: 31882152.
      View in: PubMed
    14. Mostafa S, Pakvasa M, Coalson E, Zhu A, Alverdy A, Castillo H, Fan J, Li A, Feng Y, Wu D, Bishop E, Du S, Spezia M, Li A, Hagag O, Deng A, Liu W, Li M, Ho SS, Athiviraham A, Lee MJ, Wolf JM, Ameer GA, Luu HH, Haydon RC, Strelzow J, Hynes K, He TC, Reid RR. The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine. Genes Dis. 2019 Sep; 6(3):201-223. PMID: 32042861.
      View in: PubMed
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