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Kelly Hynes

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentOrthopedic Surgery and Rehabilitation Medicine
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Kelly Hynes specializes in the diagnosis and treatment of all Orthopaedic foot and ankle conditions, including trauma, sports injuries (including foot and ankle arthroscopy), forefoot deformity (such as bunions) and degenerative disease (including total ankle arthroplasty). She provides skilled, compassionate care to treat pain and restore function for a broad range of common and complex foot and ankle disorders.

    Dr. Hynes has an interest in health care delivery and biomedical informatics. She is the Ambulatory Medical Director for the department of Orthopaedic Surgery and Rehabilitation Medicine as well as a Medical Director of Informatics for UChicago Medicine. She is also committed to the education of future generations of Orthopaedic surgeons and teaches at regional and international courses.

    Collapse Biography 
    Collapse education and training
    University of British ColumbiaFellowship
    University of OttawaResidency
    Memorial University of Newfoundland and LabradorMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nair V, Mirle V, Hynes K, Strelzow J. Efficacy of post-operative X-rays after operatively treated ankle fractures: What is their role? Injury. 2024 Jun; 55(6):111595. PMID: 38703573.
      Citations:    Fields:    Translation:Humans
    2. Liu AM, Mirle V, Lee C, Hynes K, Dirschl DR, Strelzow J. Forgetting the Frail: National Trends in Vitamin D Prescription After Fragility Fracture-A Large Insurance Claims Database Study. J Am Acad Orthop Surg. 2024 May 15; 32(10):464-471. PMID: 38484091.
      Citations:    Fields:    Translation:Humans
    3. Liu C, Kumar M, Liu A, Erdman MK, Christiano A, Lee A, Hynes K, Strelzow J. Civilian Ballistic Arthrotomies: Infection Rates and Operative Versus Nonoperative Management. J Orthop Trauma. 2024 Feb 01; 38(2):102-108. PMID: 38031279.
      Citations:    Fields:    Translation:Humans
    4. Chen K, Hynes KK, Dirschl D, Wolf JM, Strelzow JA. Depression, anxiety, and post-traumatic stress disorder following upper versus lower extremity fractures. Injury. 2024 Mar; 55(3):111242. PMID: 38044162.
      Citations:    Fields:    Translation:Humans
    5. Baker HP, Dwyer E, Kalidoss S, Hynes K, Wolf J, Strelzow JA. ChatGPT's Ability to Assist with Clinical Documentation: A Randomized Controlled Trial. J Am Acad Orthop Surg. 2024 Feb 01; 32(3):123-129. PMID: 37976385.
      Citations: 5     Fields:    Translation:Humans
    6. Litvak AL, Lin NA, Hynes KK, Strelzow JA, Conti Mica MA, Stepan JG. Are Social Deprivation and Low Traditional Health Literacy Associated With Higher PROMIS CAT Completion in Orthopaedic Surgery? Clin Orthop Relat Res. 2024 Mar 01; 482(3):442-454. PMID: 37732819; PMCID: PMC10871763.
      Citations:    Fields:    Translation:Humans
    7. Nair V, Lewis J, Daccarett M, Dirschl D, Hynes K, Strelzow J. Efficacy of Postoperative Radiographs After Intramedullary Nailing of the Tibia and Femur: When Are They Useful? J Am Acad Orthop Surg Glob Res Rev. 2023 06 01; 7(6). PMID: 37285510; PMCID: PMC10247209.
      Citations:    Fields:    Translation:Humans
    8. Baker HP, Muriuki MG, Straszewski AJ, Johnson C, Krishnan P, Hynes K, Strelzow JA, Havey RM, Dillman DB. Comparison of a Novel Modified All-Suture Construct versus Suspensory Suture-button Fixation in a Syndesmotic Injury Model. J Orthop Trauma. 2023 03 01; 37(3):e104-e110. PMID: 36219777.
      Citations:    Fields:    Translation:Humans
    9. Goldberg EM, Polachek WS, Hynes K. Ankle Fractures in Diabetic Patients: A Critical Analysis. JBJS Rev. 2023 03 01; 11(3). PMID: 36927706.
      Citations:    Fields:    Translation:Humans
    10. Cohen-Rosenblum AR, Somogyi JR, Hynes KK, Guevara ME. Orthopaedic Management of Gout. J Am Acad Orthop Surg Glob Res Rev. 2022 11 01; 6(11). PMID: 36346841; PMCID: PMC9645791.
      Citations: 1     Fields:    Translation:Humans
    11. Polachek WS, Baker HP, Dahm JS, Strelzow JA, Hynes KK. Diabetic Kidney Disease Is Associated With Increased Complications Following Operative Management of Ankle Fractures. Foot Ankle Orthop. 2022 Jul; 7(3):24730114221112106. PMID: 35898793; PMCID: PMC9309779.
    12. Kingston KA, Lin Y, Bradley AT, Strelzow J, Hynes K, Toolan BC. Salvage of Chronic Syndesmosis Instability: A Retrospective Review With Mid-Term Follow-Up. J Foot Ankle Surg. 2023 Mar-Apr; 62(2):210-217. PMID: 35927153.
      Citations: 1     Fields:    Translation:Humans
    13. Baker HP, Portney DA, Schroedl LM, Strelzow JA, Hynes K, Dillman DB. The Effect of Fascia Iliaca Compartment Blockade on Mortality in Patients With Hip Fractures: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Am Acad Orthop Surg. 2022 Feb 01; 30(3):e384-e394. PMID: 35772091.
      Citations:    Fields:    Translation:Humans
    14. Polachek WS, Baker HP, Dahm JS, Strelzow J, Hynes KK. Diabetic Kidney Disease is Associated with Increased Complications Following Operative Management of Ankle Fractures. Foot Ankle Orthop. 2022 Jan; 7(1):2473011421S00399. PMID: 35097886.
    15. Polachek WS, Lee C, Scott BL, Hynes KK. Preoperative Opioid Prescription is a Risk Factor for Extended Opioid Filling After Ankle Arthroscopy. Foot Ankle Orthop. 2022 Jan; 7(1):2473011421S00400. PMID: 35097887.
    16. Zhao X, Huang B, Wang H, Ni N, He F, Liu Q, Shi D, Chen C, Zhao P, Wang X, Wagstaff W, Pakvasa M, Tucker AB, Lee MJ, Wolf JM, Reid RR, Hynes K, Strelzow J, Ho SH, Yu T, Yang J, Shen L, He TC, Zhang Y. A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs). Am J Transl Res. 2021; 13(5):4233-4250. PMID: 34150011; PMCID: PMC8205769.
      Citations: 7     
    17. Zhao X, Hu DA, Wu D, He F, Wang H, Huang L, Shi D, Liu Q, Ni N, Pakvasa M, Zhang Y, Fu K, Qin KH, Li AJ, Hagag O, Wang EJ, Sabharwal M, Wagstaff W, Reid RR, Lee MJ, Wolf JM, El Dafrawy M, Hynes K, Strelzow J, Ho SH, He TC, Athiviraham A. Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering. Front Bioeng Biotechnol. 2021; 9:603444. PMID: 33842441; PMCID: PMC8026885.
      Citations: 24     
    18. Zhang Y, Wu D, Zhao X, Pakvasa M, Tucker AB, Luo H, Qin KH, Hu DA, Wang EJ, Li AJ, Zhang M, Mao Y, Sabharwal M, He F, Niu C, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Chen C, Wagstaff W, Reid RR, Athiviraham A, Ho S, Lee MJ, Hynes K, Strelzow J, He TC, El Dafrawy M. Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine. Front Bioeng Biotechnol. 2020; 8:598607. PMID: 33381499; PMCID: PMC7767872.
      Citations: 31     
    19. He F, Ni N, Zeng Z, Wu D, Feng Y, Li AJ, Luu B, Li AF, Qin K, Wang E, Wang X, Wu X, Luo H, Zhang J, Zhang M, Mao Y, Pakvasa M, Wagstaff W, Zhang Y, Niu C, Wang H, Huang L, Shi D, Liu Q, Zhao X, Fu K, Reid RR, Wolf JM, Lee MJ, Hynes K, Strelzow J, El Dafrawy M, Gan H, He TC, Fan J. FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells. Mol Ther Nucleic Acids. 2020 Dec 04; 22:885-899. PMID: 33230483; PMCID: PMC7658575.
      Citations: 13     
    20. Rizzi AM, Polachek WS, Dulas M, Strelzow JA, Hynes KK. The new 'normal': Rapid adoption of telemedicine in orthopaedics during the COVID-19 pandemic. Injury. 2020 Dec; 51(12):2816-2821. PMID: 32951916; PMCID: PMC7493795.
      Citations: 29     Fields:    Translation:HumansPHPublic Health
    21. Wang X, Zhao L, Wu X, Luo H, Wu D, Zhang M, Zhang J, Pakvasa M, Wagstaff W, He F, Mao Y, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Hynes K, Strelzow J, El Dafrawy M, He TC, Qi H, Zeng Z. Development of a simplified and inexpensive RNA depletion method for plasmid DNA purification using size selection magnetic beads (SSMBs). Genes Dis. 2021 May; 8(3):298-306. PMID: 33997177; PMCID: PMC8093646.
      Citations: 11     
    22. Pakvasa M, Haravu P, Boachie-Mensah M, Jones A, Coalson E, Liao J, Zeng Z, Wu D, Qin K, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Lee MJ, Wolf JM, Athiviraham A, Ho SS, He TC, Hynes K, Strelzow J, El Dafrawy M, Reid RR. Notch signaling: Its essential roles in bone and craniofacial development. Genes Dis. 2021 Jan; 8(1):8-24. PMID: 33569510; PMCID: PMC7859553.
      Citations: 24     
    23. Zhang B, Yang L, Zeng Z, Feng Y, Wang X, Wu X, Luo H, Zhang J, Zhang M, Pakvasa M, Wagstaff W, He F, Mao Y, Qin K, Ding H, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Athiviraham A, Moriatis Wolf J, Lee MJ, Hynes K, Strelzow J, El Dafrawy M, Xia Y, He TC. Leptin Potentiates BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Through the Activation of JAK/STAT Signaling. Stem Cells Dev. 2020 04 15; 29(8):498-510. PMID: 32041483; PMCID: PMC7153647.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    24. Lee CS, Divi SN, Dirschl DR, Hynes KK. Financial Impact of Magnetic Resonance Imaging in the Surgical Treatment of Foot and Ankle Osteomyelitis. J Foot Ankle Surg. 2020 Jan - Feb; 59(1):69-74. PMID: 31882152.
      Citations:    Fields:    Translation:Humans
    25. Mostafa S, Pakvasa M, Coalson E, Zhu A, Alverdy A, Castillo H, Fan J, Li A, Feng Y, Wu D, Bishop E, Du S, Spezia M, Li A, Hagag O, Deng A, Liu W, Li M, Ho SS, Athiviraham A, Lee MJ, Wolf JM, Ameer GA, Luu HH, Haydon RC, Strelzow J, Hynes K, He TC, Reid RR. The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine. Genes Dis. 2019 Sep; 6(3):201-223. PMID: 32042861; PMCID: PMC6997590.
      Citations: 53     
    26. Beaulé PE, Hynes K, Parker G, Kemp KA. Can the alpha angle assessment of cam impingement predict acetabular cartilage delamination? Clin Orthop Relat Res. 2012 Dec; 470(12):3361-7. PMID: 23001504; PMCID: PMC3492595.
      Citations: 47     Fields:    Translation:Humans
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