"Amitriptyline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
| Descriptor ID |
D000639
|
| MeSH Number(s) |
D02.455.426.559.847.181.384.100 D04.615.181.384.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Amitriptyline".
Below are MeSH descriptors whose meaning is more specific than "Amitriptyline".
This graph shows the total number of publications written about "Amitriptyline" by people in this website by year, and whether "Amitriptyline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amitriptyline" by people in Profiles.
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Amitriptyline-induced ventricular tachycardia: a case report. BMC Res Notes. 2017 Jul 14; 10(1):286.
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Medication effects on periurethral sensation and urethral sphincter activity. Female Pelvic Med Reconstr Surg. 2015 Mar-Apr; 21(2):77-82.
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Treatment modalities, health care resource utilization, and costs in patients diagnosed with interstitial cystitis. Am J Obstet Gynecol. 2008 Jul; 199(1):71.e1-10.
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The effects of antidepressants on obstructed and unobstructed gait in healthy elderly people. J Gerontol A Biol Sci Med Sci. 2001 Jan; 56(1):M36-41.
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Treatment of ciguatera fish poisoning with amitriptyline and nifedipine. J Toxicol Clin Toxicol. 1987; 25(5):423-8.
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Failure of urinary MHPG levels to predict treatment response in patients with unipolar depression. Am J Psychiatry. 1986 Nov; 143(11):1398-402.
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A placebo-controlled, double-blind trial of amitriptyline in bulimia. J Clin Psychopharmacol. 1984 Aug; 4(4):186-93.
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Effect of alcohol consumption and cigarette smoking on antidepressant levels of depressed patients. Am J Psychiatry. 1981 Jun; 138(6):841-2.
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Prediction of tricyclic antidepressant response: a critical review. Arch Gen Psychiatry. 1976 Dec; 33(12):1479-89.
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Catecholamine metabolism in affective disorders. IV. Preliminary studies of norepinephrine metabolism in depressed patients treated with amitriptyline. J Psychiatr Res. 1972 Sep; 9(3):173-85.