"Antigenic Variation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Change in the surface ANTIGEN of a microorganism. There are two different types. One is a phenomenon, especially associated with INFLUENZA VIRUSES, where they undergo spontaneous variation both as slow antigenic drift and sudden emergence of new strains (antigenic shift). The second type is when certain PARASITES, especially trypanosomes, PLASMODIUM, and BORRELIA, survive the immune response of the host by changing the surface coat (antigen switching). (From Herbert et al., The Dictionary of Immunology, 4th ed)
| Descriptor ID |
D000940
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| MeSH Number(s) |
G05.365.073 G12.500.249
|
| Concept/Terms |
Antigenic Variation- Antigenic Variation
- Antigenic Variability
- Variability, Antigenic
- Variation, Antigenic
- Antigen Variation
- Variation, Antigen
Antigen Switching- Antigen Switching
- Switching, Antigen
- Switching, Antigenic
- Antigenic Switching
|
Below are MeSH descriptors whose meaning is more general than "Antigenic Variation".
Below are MeSH descriptors whose meaning is more specific than "Antigenic Variation".
This graph shows the total number of publications written about "Antigenic Variation" by people in this website by year, and whether "Antigenic Variation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antigenic Variation" by people in Profiles.
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A speed limit on serial strain replacement from original antigenic sin. Proc Natl Acad Sci U S A. 2024 Jun 18; 121(25):e2400202121.
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An antigenic diversification threshold for falciparum malaria transmission at high endemicity. PLoS Comput Biol. 2021 02; 17(2):e1008729.
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Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in Plasmodium falciparum. PLoS Biol. 2019 06; 17(6):e3000336.
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Estimating Vaccine-Driven Selection in Seasonal Influenza. Viruses. 2018 09 18; 10(9).
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Identifying functional groups among the diverse, recombining antigenic var genes of the malaria parasite Plasmodium falciparum from a local community in Ghana. PLoS Comput Biol. 2018 06; 14(6):e1006174.
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Harnessing immune history to combat influenza viruses. Curr Opin Immunol. 2018 08; 53:187-195.
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From Original Antigenic Sin to the Universal Influenza Virus Vaccine. Trends Immunol. 2018 01; 39(1):70-79.
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Explaining the geographical origins of seasonal influenza A (H3N2). Proc Biol Sci. 2016 09 14; 283(1838).
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Selection of antigenically advanced variants of seasonal influenza viruses. Nat Microbiol. 2016 05 23; 1(6):16058.
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Tumor Heterogeneity and Tumor Immunity: A Chicken-and-Egg Problem. Trends Immunol. 2016 06; 37(6):349-351.