Carbamoyl-Phosphate Synthase (Ammonia)
"Carbamoyl-Phosphate Synthase (Ammonia)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle. Absence or lack of this enzyme may cause CARBAMOYL-PHOSPHATE SYNTHASE I DEFICIENCY DISEASE. EC 6.3.4.16.
Descriptor ID |
D002222
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MeSH Number(s) |
D08.811.464.259.350
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Concept/Terms |
Carbamoyl-Phosphate Synthase (Ammonia)- Carbamoyl-Phosphate Synthase (Ammonia)
- Carbamyl Phosphate Synthase (Ammonia)
- Carbamyl-Phosphate Synthase (Ammonia)
- Carbamoyl-Phosphate Synthetase I
- Synthetase I, Carbamoyl-Phosphate
- Carbamoyl-Phosphate Synthetase (Ammonia)
- Carbamoyl Phosphate Synthetase I
- Carbamoylphosphate Synthetase I
- Synthetase I, Carbamoylphosphate
- CP Synthase I
- Synthase I, CP
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Below are MeSH descriptors whose meaning is more general than "Carbamoyl-Phosphate Synthase (Ammonia)".
Below are MeSH descriptors whose meaning is more specific than "Carbamoyl-Phosphate Synthase (Ammonia)".
This graph shows the total number of publications written about "Carbamoyl-Phosphate Synthase (Ammonia)" by people in this website by year, and whether "Carbamoyl-Phosphate Synthase (Ammonia)" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carbamoyl-Phosphate Synthase (Ammonia)" by people in Profiles.
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CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells. Nature. 2017 06 01; 546(7656):168-172.
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Lysine glutarylation is a protein posttranslational modification regulated by SIRT5. Cell Metab. 2014 Apr 01; 19(4):605-17.
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Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science. 2011 Nov 11; 334(6057):806-9.
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Liver transplantation for the treatment of urea cycle disorders. J Inherit Metab Dis. 1998; 21 Suppl 1:112-8.
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Neurologic outcome in children with inborn errors of urea synthesis. Outcome of urea-cycle enzymopathies. N Engl J Med. 1984 Jun 07; 310(23):1500-5.