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Thomas Chen

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Hospital Medicine
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Chen is interested in pharmacogenomics, medical education, and hospital medicine. He has a particular interest in the medication reconciliation process, prescribing, and quality improvements that decrease costs of care and improve health outcomes. He is also Co-Director of the Personalized Therapeutics Clinic.

    Collapse Biography 
    Collapse education and training
    University of Illinois at Chicago, ChicagoPharmD05/2009
    University of Illinois at Chicago, ChicagoMD05/2014
    Johns Hopkins Hospital, BaltimoreResidency06/2017Internal Medicine

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Huang Z, O'Leary KJ, Nutescu EA, Jack M, Chen T, Ruhnke GW, Lee JC, George D, House LK, Knoebel R, Rasmussen LV, Hartman S, Choksi A, Yeo KJ, Perera MA, Ratain MJ, Meltzer DO, O'Donnell PH. Results of the ACCOuNT Trial: A Multi-Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients. Clin Pharmacol Ther. 2026 01; 119(1):109-119. PMID: 40847467; PMCID: PMC12746525.
      Citations:    Fields:    Translation:Humans
    2. Huang Z, Jack M, O'Leary KJ, Nutescu EA, Chen T, Ruhnke GW, George D, House LK, Knoebel R, Hartman S, Choksi A, Yeo KJ, Perera MA, Ratain MJ, Meltzer DO, O'Donnell PH. Care Team Attributes Predict Likelihood of Utilizing Pharmacogenomic Information During Inpatient Prescribing. Clin Transl Sci. 2025 04; 18(4):e70193. PMID: 40259529; PMCID: PMC12011642.
      Citations: 1     Fields:    Translation:Humans
    3. Virgilio MC, Ramnani B, Chen T, Disbennett WM, Lubow J, Welch JD, Collins KL. HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages. Nat Commun. 2024 06 29; 15(1):5514. PMID: 38951492; PMCID: PMC11217462.
      Citations: 7     Fields:    Translation:HumansCells
    4. Shiroishi MS, Weinert D, Cen SY, Varghese B, Dondlinger T, Prah M, Mendoza J, Nazemi S, Ameli N, Amini N, Shohas S, Chen S, Bigjahan B, Zada G, Chen T, Neman-Ebrahim J, Chang EL, Chow FE, Fan Z, Yang W, Attenello FJ, Ye J, Kim PE, Patel VN, Lerner A, Acharya J, Hu LS, Quarles CC, Boxerman JL, Wu O, Schmainda KM. A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength. Front Oncol. 2023; 13:1156843. PMID: 37799462; PMCID: PMC10548232.
      Citations: 5     
    5. Hopkins BS, Cloney MB, Dhillon ES, Texakalidis P, Dallas J, Nguyen VN, Ordon M, Tecle NE, Chen TC, Hsieh PC, Liu JC, Koski TR, Dahdaleh NS. Using machine learning and big data for the prediction of venous thromboembolic events after spine surgery: A single-center retrospective analysis of multiple models on a cohort of 6869 patients. J Craniovertebr Junction Spine. 2023 Jul-Sep; 14(3):221-229. PMID: 37860027; PMCID: PMC10583792.
      Citations: 2     
    6. Chen T, O'Donnell PH, Middlestadt M, Ruhnke GW, Danahey K, van Wijk XMR, Choksi A, Knoebel R, Hartman S, Yeo KJ, Friedman PN, Ratain MJ, Nutescu EA, O'Leary KJ, Perera MA, Meltzer DO. Implementation of pharmacogenomics into inpatient general medicine. Pharmacogenet Genomics. 2023 02 01; 33(2):19-23. PMID: 36729768.
      Citations: 9     Fields:    Translation:Humans
    7. Saulsberry L, Danahey K, Middlestadt M, O'Leary KJ, Nutescu EA, Chen T, Lee JC, Ruhnke GW, George D, House L, van Wijk XMR, Yeo KJ, Choksi A, Hartman SW, Knoebel RW, Friedman PN, Rasmussen LV, Ratain MJ, Perera MA, Meltzer DO, O'Donnell PH. Applicability of Pharmacogenomically Guided Medication Treatment during Hospitalization of At-Risk Minority Patients. J Pers Med. 2021 Dec 10; 11(12). PMID: 34945816; PMCID: PMC8709436.
      Citations: 3     
    8. Choksi TT, Zhang H, Chen T, Malhotra N. Outcomes of Hospitalized COVID-19 Patients Receiving Renin Angiotensin System Blockers and Calcium Channel Blockers. Am J Nephrol. 2021; 52(3):250-260. PMID: 33827074; PMCID: PMC8089461.
      Citations: 10     Fields:    Translation:Humans
    9. Barkoudah E, Piazza G, Hecht TEH, Grant P, Deitelzweig S, Fang MC, Fanikos J, Kao CK, Barnes GD, Chen T, Schnipper JL, Goldstein JN, Ruff CT, Kaatz S, Schwartz A, Connors JM, Goldhaber SZ, Ramishvili T. Extended Venous Thromboembolism Prophylaxis in Medically Ill Patients: An NATF Anticoagulation Action Initiative. Am J Med. 2020 05; 133 Suppl 1:1-27. PMID: 32362349.
      Citations: 13     Fields:    Translation:Humans
    10. Danilov CA, Gu Y, Punj V, Wu Z, Steward O, Schönthal AH, Tahara SM, Hofman FM, Chen TC. Intravenous delivery of microRNA-133b along with Argonaute-2 enhances spinal cord recovery following cervical contusion in mice. Spine J. 2020 07; 20(7):1138-1151. PMID: 32145360.
      Citations: 11     Fields:    Translation:Animals
    11. Chen SH, Sun JM, Chen BM, Lin SC, Chang HF, Collins S, Chang D, Wu SF, Lu YC, Wang W, Chen TC, Kasahara N, Wang HE, Tai CK. Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model. Int J Mol Sci. 2020 Feb 20; 21(4). PMID: 32093290; PMCID: PMC7073086.
      Citations: 7     Fields:    Translation:AnimalsCells
    12. Wu AH, Wu J, Tseng C, Yang J, Shariff-Marco S, Fruin S, Larson T, Setiawan VW, Masri S, Porcel J, Jain J, Chen TC, Stram DO, Marchand LL, Ritz B, Cheng I. Association Between Outdoor Air Pollution and Risk of Malignant and Benign Brain Tumors: The Multiethnic Cohort Study. JNCI Cancer Spectr. 2020 Apr; 4(2):pkz107. PMID: 32211584; PMCID: PMC7083235.
      Citations: 13     Fields:    
    13. Song X, Liu L, Chang M, Geng X, Wang X, Wang W, Chen TC, Xie L, Song X. NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer. J Exp Clin Cancer Res. 2019 Jun 07; 38(1):239. PMID: 31174569; PMCID: PMC6554966.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    14. Taphoorn MJB, Dirven L, Kanner AA, Lavy-Shahaf G, Weinberg U, Taillibert S, Toms SA, Honnorat J, Chen TC, Sroubek J, David C, Idbaih A, Easaw JC, Kim CY, Bruna J, Hottinger AF, Kew Y, Roth P, Desai R, Villano JL, Kirson ED, Ram Z, Stupp R. Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2018 Apr 01; 4(4):495-504. PMID: 29392280; PMCID: PMC5885193.
      Citations: 116     Fields:    Translation:HumansCTClinical Trials
    15. Kushal S, Wang W, Vaikari VP, Kota R, Chen K, Yeh TS, Jhaveri N, Groshen SL, Olenyuk BZ, Chen TC, Hofman FM, Shih JC. Monoamine oxidase A (MAO A) inhibitors decrease glioma progression. Oncotarget. 2016 Mar 22; 7(12):13842-53. PMID: 26871599; PMCID: PMC4924682.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    16. Stupp R, Taillibert S, Kanner AA, Kesari S, Steinberg DM, Toms SA, Taylor LP, Lieberman F, Silvani A, Fink KL, Barnett GH, Zhu JJ, Henson JW, Engelhard HH, Chen TC, Tran DD, Sroubek J, Tran ND, Hottinger AF, Landolfi J, Desai R, Caroli M, Kew Y, Honnorat J, Idbaih A, Kirson ED, Weinberg U, Palti Y, Hegi ME, Ram Z. Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial. JAMA. 2015 Dec 15; 314(23):2535-43. PMID: 26670971.
      Citations: 681     Fields:    Translation:HumansCTClinical Trials
    17. Chen T, Meng X, Zhang H, Tsang RW, Tsang TK. Comparing Multiplex PCR and Rapid Urease Test in the Detection of H. pylori in Patients on Proton Pump Inhibitors. Gastroenterol Res Pract. 2012; 2012:898276. PMID: 23319944; PMCID: PMC3540742.
      Citations: 10     
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