Glomerulosclerosis, Focal Segmental
"Glomerulosclerosis, Focal Segmental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
| Descriptor ID |
D005923
|
| MeSH Number(s) |
C12.777.419.570.363.660 C13.351.968.419.570.363.640
|
| Concept/Terms |
Glomerulosclerosis, Focal Segmental- Glomerulosclerosis, Focal Segmental
- Segmental Glomerulosclerosis, Focal
- Glomerulosclerosis, Focal
- Focal Glomerulosclerosis
- Focal Segmental Glomerulosclerosis
- Glomerulonephritis, Focal Sclerosing
- Focal Sclerosing Glomerulonephritides
- Focal Sclerosing Glomerulonephritis
- Glomerulonephritides, Focal Sclerosing
- Sclerosing Glomerulonephritides, Focal
- Sclerosing Glomerulonephritis, Focal
Hyalinosis, Segmental Glomerular- Hyalinosis, Segmental Glomerular
- Glomerular Hyalinosis, Segmental
- Segmental Glomerular Hyalinosis
- Hyalinosis, Segmental
- Segmental Hyalinosis
|
Below are MeSH descriptors whose meaning is more general than "Glomerulosclerosis, Focal Segmental".
Below are MeSH descriptors whose meaning is more specific than "Glomerulosclerosis, Focal Segmental".
This graph shows the total number of publications written about "Glomerulosclerosis, Focal Segmental" by people in this website by year, and whether "Glomerulosclerosis, Focal Segmental" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glomerulosclerosis, Focal Segmental" by people in Profiles.
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Podocyte injury at young age causes premature senescence and worsens glomerular aging. Am J Physiol Renal Physiol. 2024 01 01; 326(1):F120-F134.
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Upregulated PD-1 signaling antagonizes glomerular health in aged kidneys and disease. J Clin Invest. 2022 08 15; 132(16).
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Digital spatial profiling of collapsing glomerulopathy. Kidney Int. 2022 05; 101(5):1017-1026.
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Quantification of Glomerular Structural Lesions: Associations With Clinical Outcomes and Transcriptomic Profiles in Nephrotic Syndrome. Am J Kidney Dis. 2022 06; 79(6):807-819.e1.
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The Importance of Nephropathology in Kidney Cancer. Semin Nephrol. 2020 01; 40(1):69-75.
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Differential expression of parietal epithelial cell and podocyte extracellular matrix proteins in focal segmental glomerulosclerosis and diabetic nephropathy. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1680-F1694.
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Cryptococcal cellulitis on the shin of an immunosuppressed patient. Dermatol Online J. 2016 Jun 15; 22(6).
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Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS. J Am Soc Nephrol. 2014 Nov; 25(11):2459-70.
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Hypoxia-inducible factor-2a and TGF-ß signaling interact to promote normoxic glomerular fibrogenesis. Am J Physiol Renal Physiol. 2013 Nov 01; 305(9):F1323-31.
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A study of interobserver reproducibility of morphologic lesions of focal segmental glomerulosclerosis. Virchows Arch. 2013 Feb; 462(2):229-37.