An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)

Descriptor ID	D004402
MeSH Number(s)	C10.177.575.300 C10.500.310.309 C10.574.500.496.250 C10.668.829.800.175.250 C16.131.666.310.309 C16.320.400.415.309
Concept/Terms	Dysautonomia, Familial Dysautonomia, Familial HSAN Type III Riley-Day Syndrome Riley Day Syndrome Hereditary-Sensory and Autonomic Neuropathy Type III Hereditary Sensory and Autonomic Neuropathy Type III Neuropathy, Hereditary and Autonomic, Type III Dominant Hereditary Sensory Neuropathy, Type III Hereditary Sensory Neuropathy, Dominant, Type 3 Hereditary Sensory Neuropathy, Dominant, Type III HSN-III HSAN (Hereditary Sensory and Autonomic Neuropathy) Type III Type III Hereditary Sensory Neuropathy, Dominant Type 3 Hereditary Sensory Neuropathy, Dominant HSAN 3 Hereditary Sensory Neuropathy Type 3 Hereditary Sensory and Autonomic Neuropathy 3 HSAN III Familial Dysautonomia HSAN3 Neuropathy, Hereditary Sensory And Autonomic, Type III Hereditary Sensory Neuropathy, Type 3, Dominant

Below are MeSH descriptors whose meaning is more general than "Dysautonomia, Familial".

Below are MeSH descriptors whose meaning is related to "Dysautonomia, Familial".

Below are MeSH descriptors whose meaning is more specific than "Dysautonomia, Familial".