"Freeze Etching" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A replica technique in which cells are frozen to a very low temperature and cracked with a knife blade to expose the interior surfaces of the cells or cell membranes. The cracked cell surfaces are then freeze-dried to expose their constituents. The surfaces are now ready for shadowing to be viewed using an electron microscope. This method differs from freeze-fracturing in that no cryoprotectant is used and, thus, allows for the sublimation of water during the freeze-drying process to etch the surfaces.
| Descriptor ID |
D005613
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| MeSH Number(s) |
E01.370.225.500.620.620.260.400 E01.370.225.750.600.620.260.400 E05.200.500.620.620.260.400 E05.200.750.600.620.260.400
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Freeze Etching".
Below are MeSH descriptors whose meaning is more specific than "Freeze Etching".
This graph shows the total number of publications written about "Freeze Etching" by people in this website by year, and whether "Freeze Etching" was a major or minor topic of these publications.
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Below are the most recent publications written about "Freeze Etching" by people in Profiles.
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Ultrastructural characterization of proteins at the natural surfaces of the red cell membrane. Prog Clin Biol Res. 1978; 21:413-29.
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Inside-out red cell membrane vesicles: preparation and purification. Science. 1970 Apr 10; 168(3928):255-7.