"Galactosylceramidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that hydrolyzes galactose from ceramide monohexosides. Deficiency of this enzyme may cause globoid cell leukodystrophy (LEUKODYSTROPHY, GLOBOID CELL). EC 3.2.1.46.
| Descriptor ID |
D005698
|
| MeSH Number(s) |
D08.811.277.450.410.120
|
| Concept/Terms |
Galactosylceramidase- Galactosylceramidase
- Galactosylcerebroside beta-Galactosidase
- beta-Galactosidase, Galactosylcerebroside
- Galactosylceramide Galactosidase
- Galactosidase, Galactosylceramide
- Galactocerebrosidase
- Galactosylceramide beta-Galactosidase
- beta-Galactosidase, Galactosylceramide
|
Below are MeSH descriptors whose meaning is more general than "Galactosylceramidase".
Below are MeSH descriptors whose meaning is more specific than "Galactosylceramidase".
This graph shows the total number of publications written about "Galactosylceramidase" by people in this website by year, and whether "Galactosylceramidase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Galactosylceramidase" by people in Profiles.
-
Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease. Mol Ther. 2021 05 05; 29(5):1883-1902.
-
Twitcher mice with only a single active galactosylceramide synthase gene exhibit clearly detectable but therapeutically minor phenotypic improvements. J Neurosci Res. 2000 Jan 15; 59(2):179-87.
-
Biochemistry and neuropathology of mice doubly deficient in synthesis and degradation of galactosylceramide. J Neurosci Res. 2000 Jan 15; 59(2):170-8.
-
Correction of the galactocerebrosidase deficiency in globoid cell leukodystrophy-cultured cells by SL3-3 retroviral-mediated gene transfer. Biochem Biophys Res Commun. 1996 Jan 26; 218(3):766-71.