Immunoglobulin gamma-Chains
"Immunoglobulin gamma-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.
Descriptor ID |
D007142
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MeSH Number(s) |
D12.776.124.486.485.114.619.393.522 D12.776.124.486.485.705.500.380 D12.776.124.790.651.114.619.393.522 D12.776.124.790.651.705.500.380 D12.776.377.715.548.114.619.393.522 D12.776.377.715.548.705.500.380
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Concept/Terms |
Immunoglobulin gamma-Chains- Immunoglobulin gamma-Chains
- Immunoglobulin gamma Chains
- gamma-Chains, Immunoglobulin
- Immunoglobulins, gamma-Chain
- Immunoglobulins, gamma Chain
- gamma-Chain Immunoglobulins
- gamma Chain Immunoglobulins
- Immunoglobulin gamma-Chain
- Immunoglobulin gamma Chain
- gamma-Chain, Immunoglobulin
- gamma Immunoglobulin Heavy Chain
- gamma Immunoglobulin Heavy Chains
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin gamma-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin gamma-Chains".
This graph shows the total number of publications written about "Immunoglobulin gamma-Chains" by people in this website by year, and whether "Immunoglobulin gamma-Chains" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1997 | 0 | 1 | 1 |
1999 | 1 | 0 | 1 |
2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin gamma-Chains" by people in Profiles.
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Induced expression of murine gamma2a by CD40 ligation independently of IFN-gamma. J Immunol. 2006 Oct 15; 177(8):5414-9.
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The C(H)1 and transmembrane domains of mu in the context of a gamma2b transgene do not suffice to promote B cell maturation. Int Immunol. 1999 Oct; 11(10):1663-71.
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Gamma 2b provides only some of the signals normally given via mu in B cell development. Int Immunol. 1997 Mar; 9(3):415-26.
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lambda 5, but not mu, is required for B cell maturation in a unique gamma 2b transgenic mouse line. J Exp Med. 1995 Mar 01; 181(3):1059-70.
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Delay of early B-lymphocyte development by gamma 2b immunoglobulin transgene: effect on differentiation-specific molecules. Dev Immunol. 1990; 1(2):105-12.
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Isoelectric focusing studies of serum and cerebrospinal fluid in patients with antecedent poliomyelitis. Ann Neurol. 1989 Dec; 26(6):709-13.
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Oligoclonal IgG bands in cerebrospinal fluid and serum during asymptomatic human immunodeficiency virus infection. Ann Neurol. 1988 Aug; 24(2):277-9.
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An isoelectric focusing study in herpes simplex virus encephalitis. Ann Neurol. 1988 Aug; 24(2):227-32.
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Cloning of a gamma 2b gene encoding anti-Pseudomonas aeruginosa H chains and its introduction into the germ line of mice. J Immunol. 1988 Jul 01; 141(1):308-14.
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Immunoglobulin mu- and gamma-ribonucleic acid sequences in thymocytes and splenocytes from normal and hyperimmune mice. Biochemistry. 1981 Apr 28; 20(9):2386-94.