"Lipoproteins, LDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.
| Descriptor ID |
D008077
|
| MeSH Number(s) |
D10.532.515 D12.776.521.550
|
| Concept/Terms |
Lipoproteins, LDL- Lipoproteins, LDL
- LDL Lipoproteins
- Low-Density Lipoproteins
- Lipoproteins, Low-Density
- Low Density Lipoproteins
- beta-Lipoproteins
- beta Lipoproteins
LDL-1- LDL-1
- LDL1
- Low-Density Lipoprotein 1
- Low Density Lipoprotein 1
- LDL(1)
LDL-2- LDL-2
- LDL2
- Low-Density Lipoprotein 2
- Low Density Lipoprotein 2
- LDL(2)
|
Below are MeSH descriptors whose meaning is more general than "Lipoproteins, LDL".
Below are MeSH descriptors whose meaning is more specific than "Lipoproteins, LDL".
This graph shows the total number of publications written about "Lipoproteins, LDL" by people in this website by year, and whether "Lipoproteins, LDL" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 1 | 3 |
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 3 | 0 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 2 | 2 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 4 | 6 |
| 2009 | 2 | 1 | 3 |
| 2010 | 1 | 2 | 3 |
| 2011 | 2 | 3 | 5 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 3 | 1 | 4 |
| 2017 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Lipoproteins, LDL" by people in Profiles.
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High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity. J Am Heart Assoc. 2023 02 07; 12(3):e8145.
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Tumor-Activatable Nanoparticles Target Low-Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy. Adv Sci (Weinh). 2022 08; 9(24):e2201614.
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A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis. Nat Genet. 2020 11; 52(11):1239-1246.
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Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. Atherosclerosis. 2019 10; 289:184-194.
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Opportunities and challenges for transcriptome-wide association studies. Nat Genet. 2019 04; 51(4):592-599.
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Occupational Exposures and Metabolic Syndrome Among Hispanics/Latinos: Cross-Sectional Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). J Occup Environ Med. 2017 11; 59(11):1047-1055.
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Proatherogenic Flow Increases Endothelial Stiffness via Enhanced CD36-Mediated Uptake of Oxidized Low-Density Lipoproteins. Arterioscler Thromb Vasc Biol. 2018 01; 38(1):64-75.
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The effect of omega-3 carboxylic acids on apolipoprotein CIII-containing lipoproteins in severe hypertriglyceridemia. J Clin Lipidol. 2016 Nov - Dec; 10(6):1442-1451.e4.
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Enzymatically Modified Low-Density Lipoprotein Promotes Foam Cell Formation in Smooth Muscle Cells via Macropinocytosis and Enhances Receptor-Mediated Uptake of Oxidized Low-Density Lipoprotein. Arterioscler Thromb Vasc Biol. 2016 06; 36(6):1101-13.
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Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation. J Lipid Res. 2016 05; 57(5):791-808.