"Lipoproteins, LDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.
| Descriptor ID |
D008077
|
| MeSH Number(s) |
D10.532.515 D12.776.521.550
|
| Concept/Terms |
Lipoproteins, LDL- Lipoproteins, LDL
- LDL Lipoproteins
- Low-Density Lipoproteins
- Lipoproteins, Low-Density
- Low Density Lipoproteins
- beta-Lipoproteins
- beta Lipoproteins
LDL-1- LDL-1
- LDL1
- Low-Density Lipoprotein 1
- Low Density Lipoprotein 1
- LDL(1)
LDL-2- LDL-2
- LDL2
- Low-Density Lipoprotein 2
- Low Density Lipoprotein 2
- LDL(2)
|
Below are MeSH descriptors whose meaning is more general than "Lipoproteins, LDL".
Below are MeSH descriptors whose meaning is more specific than "Lipoproteins, LDL".
This graph shows the total number of publications written about "Lipoproteins, LDL" by people in this website by year, and whether "Lipoproteins, LDL" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 3 | 0 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 2 | 2 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 4 | 6 |
| 2009 | 2 | 1 | 3 |
| 2010 | 1 | 2 | 3 |
| 2011 | 3 | 3 | 6 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 3 | 0 | 3 |
| 2017 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
| 2026 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Lipoproteins, LDL" by people in Profiles.
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The LOX-1 scavenger receptor plays a central role in multiple positive feedback loops driving the escalation of oxLDL uptake by macrophages. FEBS Lett. 2026 03; 600(5):669-679.
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LDL-binding IL-10 reduces vascular inflammation in atherosclerotic mice. Nat Biomed Eng. 2026 Sep; 10(9):1843-1854.
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Inhibition of oxidized low-density lipoprotein with orticumab inhibits coronary inflammation and reduces residual inflammatory risk in psoriasis: a pilot randomized, double-blind placebo-controlled trial. Cardiovasc Res. 2024 05 29; 120(7):678-680.
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Greater sleep variability is associated with higher systemic inflammation in type 2 diabetes. J Sleep Res. 2024 05; 33(3):e13989.
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High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity. J Am Heart Assoc. 2023 02 07; 12(3):e8145.
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Tumor-Activatable Nanoparticles Target Low-Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy. Adv Sci (Weinh). 2022 08; 9(24):e2201614.
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A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis. Nat Genet. 2020 11; 52(11):1239-1246.
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Mulberry Fruit Extract Promotes Serum HDL-Cholesterol Levels and Suppresses Hepatic microRNA-33 Expression in Rats Fed High Cholesterol/Cholic Acid Diet. Nutrients. 2020 May 21; 12(5).
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Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. Atherosclerosis. 2019 10; 289:184-194.
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Opportunities and challenges for transcriptome-wide association studies. Nat Genet. 2019 04; 51(4):592-599.