"Phosphoramide Mustards" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of nitrogen mustard compounds which are substituted with a phosphoramide group or its derivatives. They are usually cytotoxic and used as antineoplastic agents.
| Descriptor ID |
D010752
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| MeSH Number(s) |
D02.455.526.728.650.730 D02.705.672.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phosphoramide Mustards".
Below are MeSH descriptors whose meaning is more specific than "Phosphoramide Mustards".
This graph shows the total number of publications written about "Phosphoramide Mustards" by people in this website by year, and whether "Phosphoramide Mustards" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphoramide Mustards" by people in Profiles.
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Population pharmacokinetics of cyclophosphamide and metabolites in children with neuroblastoma: a report from the Children's Oncology Group. J Clin Pharmacol. 2009 Jan; 49(1):88-102.
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1,3- vs 1,5-intramolecular alkylation reactions in isophosphoramide and phosphoramide mustards. Chem Res Toxicol. 2004 Sep; 17(9):1217-26.
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Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells. Mol Cancer Ther. 2001 Nov; 1(1):21-8.
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Synthesis and evaluation of pteroic acid-conjugated nitroheterocyclic phosphoramidates as folate receptor-targeted alkylating agents. J Med Chem. 2001 Jan 04; 44(1):69-73.
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Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity. Cancer Res. 1999 Jul 01; 59(13):3059-63.