"Methyl Methanesulfonate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkylating agent in cancer therapy that may also act as a mutagen by interfering with and causing damage to DNA.
| Descriptor ID |
D008741
|
| MeSH Number(s) |
D02.455.326.146.100.050.500.500 D02.886.645.600.055.050.510.500
|
| Concept/Terms |
Methyl Methanesulfonate- Methyl Methanesulfonate
- Methanesulfonate, Methyl
- Methyl Methylenesulfonate
- Methylmesilate
- Methylmethane Sulfonate
- Mesilate, Methyl
- Methyl Mesilate
- Methyl Mesylate
- Mesylate, Methyl
|
Below are MeSH descriptors whose meaning is more general than "Methyl Methanesulfonate".
Below are MeSH descriptors whose meaning is more specific than "Methyl Methanesulfonate".
This graph shows the total number of publications written about "Methyl Methanesulfonate" by people in this website by year, and whether "Methyl Methanesulfonate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methyl Methanesulfonate" by people in Profiles.
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Catalytic and non-catalytic roles of DNA polymerase ? in the protection of human cells against genotoxic stresses. Environ Mol Mutagen. 2015 Oct; 56(8):650-62.
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Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR. Genetics. 2003 Jun; 164(2):589-601.
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Vertebrate cells lacking FEN-1 endonuclease are viable but hypersensitive to methylating agents and H2O2. Nucleic Acids Res. 2002 Jul 15; 30(14):3273-7.
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Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy. Biochemistry. 2002 Jan 22; 41(3):797-808.
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Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene. 2000 Apr 13; 19(16):1975-81.
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Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms. J Biol Chem. 1996 Sep 27; 271(39):23775-9.
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Irreversible inhibition of the human placental NADP-linked 15-hydroxyprostaglandin dehydrogenase/9-ketoprostaglandin reductase by glutathione thiosulfonate. Prostaglandins. 1987 Mar; 33(3):391-402.