SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells.

SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells. Clin Cancer Res. 2017 Sep 01; 23(17):5162-5175.

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subject areas

Aged
Animals
Antibodies, Monoclonal, Humanized
Cell Line, Tumor
Cetuximab
Drug Resistance, Neoplasm
ErbB Receptors
Female
Gene Expression Regulation, Neoplastic
Head and Neck Neoplasms
Humans
MAP Kinase Kinase 1
Mice
Middle Aged
Neoplasm Recurrence, Local
Papillomaviridae
Protein Kinase Inhibitors
Smad4 Protein
Xenograft Model Antitumor Assays

authors with profiles

Evgeny Izumchenko