"Pepsin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
| Descriptor ID |
D010434
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| MeSH Number(s) |
D08.811.277.656.074.500.700 D08.811.277.656.300.048.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pepsin A".
Below are MeSH descriptors whose meaning is more specific than "Pepsin A".
This graph shows the total number of publications written about "Pepsin A" by people in this website by year, and whether "Pepsin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pepsin A" by people in Profiles.
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Optimization of Enzymatic Antibody Fragmentation for Yield, Efficiency, and Binding Affinity. Bioconjug Chem. 2019 03 20; 30(3):800-807.
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OKT3 F(ab')2 fragments--retention of the immunosuppressive properties of whole antibody with marked reduction in T cell activation and lymphokine release. Transplantation. 1991 Aug; 52(2):354-60.
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Intermolecular interaction studies on native and enzyme-treated acid-soluble collagen. Biochim Biophys Acta. 1978 Feb 15; 532(2):305-14.
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Immunological enhancement of renal allografts. Transplant Proc. 1974 Dec; 6(4 Suppl 1):53-8.
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Renal transplantation in the rabbit. I. Development of a model for study of hyperacute rejection and immunological enhancement. Transplantation. 1972 Mar; 13(3):244-9.
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Pseudomonas denitrificans cytochrome cc'. Arch Biochem Biophys. 1970 Dec; 141(2):557-70.
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Cytochrome c2 of Rhodospirillum rubrum. II. Complete amino acid sequence and phylogenetic relationships. J Biol Chem. 1968 Oct 25; 243(20):5507-18.