Neuroleptic Malignant Syndrome
"Neuroleptic Malignant Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Descriptor ID |
D009459
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| MeSH Number(s) |
C10.228.140.079.737 C10.720.737 C25.723.705.600
|
| Concept/Terms |
Neuroleptic Malignant Syndrome- Neuroleptic Malignant Syndrome
- Neuroleptic Malignant Syndromes
- Syndrome, Neuroleptic Malignant
- Syndromes, Neuroleptic Malignant
- NMS (Neuroleptic Malignant Syndrome)
- NMSs (Neuroleptic Malignant Syndrome)
Neuroleptic-Induced Neuroleptic Malignant Syndrome- Neuroleptic-Induced Neuroleptic Malignant Syndrome
- Neuroleptic Induced Neuroleptic Malignant Syndrome
- Neuroleptic-Malignant Syndrome, Neuroleptic Induced
- Neuroleptic Malignant Syndrome, Neuroleptic Induced
|
Below are MeSH descriptors whose meaning is more general than "Neuroleptic Malignant Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Neuroleptic Malignant Syndrome".
This graph shows the total number of publications written about "Neuroleptic Malignant Syndrome" by people in this website by year, and whether "Neuroleptic Malignant Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neuroleptic Malignant Syndrome" by people in Profiles.
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Aripiprazole and atypical neuroleptic malignant syndrome. J Am Acad Child Adolesc Psychiatry. 2004 Dec; 43(12):1457-8.
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Structural change in dopamine D2 receptor gene in a patient with neuroleptic malignant syndrome. Am J Med Genet. 1995 Jun 19; 60(3):228-30.
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The neuroleptic malignant syndrome and acute renal failure. J Am Soc Nephrol. 1994 Jan; 4(7):1406-12.
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Treatment of neuroleptic malignant syndrome with diphenhydramine. Vet Hum Toxicol. 1988 Feb; 30(1):58-9.