"L-Lactate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
| Descriptor ID |
D007770
|
| MeSH Number(s) |
D08.811.682.047.551.400 D08.811.682.047.820.493
|
| Concept/Terms |
L-Lactate Dehydrogenase- L-Lactate Dehydrogenase
- Dehydrogenase, L-Lactate
- L Lactate Dehydrogenase
- Lactate Dehydrogenase
- Dehydrogenase, Lactate
|
Below are MeSH descriptors whose meaning is more general than "L-Lactate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "L-Lactate Dehydrogenase".
This graph shows the total number of publications written about "L-Lactate Dehydrogenase" by people in this website by year, and whether "L-Lactate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 1 | 1 | 2 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 3 | 3 |
| 2014 | 2 | 2 | 4 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 2 | 2 |
| 2018 | 1 | 2 | 3 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "L-Lactate Dehydrogenase" by people in Profiles.
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Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression. Nat Commun. 2024 Mar 05; 15(1):1987.
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Reducing Specimen Rejection Rates Using Concentration-Dependent Hemolysis Rejection Thresholds. J Appl Lab Med. 2023 03 06; 8(2):285-295.
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A nomogram of clinical and biologic factors to predict survival in children newly diagnosed with high-risk neuroblastoma: An International Neuroblastoma Risk Group project. Pediatr Blood Cancer. 2021 03; 68(3):e28794.
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The prognostic strength of serum LDH and serum ferritin in children with neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project. Pediatr Blood Cancer. 2020 08; 67(8):e28359.
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Understanding the Value of Tumor Markers in Pediatric Ovarian Neoplasms. J Pediatr Surg. 2020 Jan; 55(1):122-125.
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Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells. J Clin Invest. 2019 03 01; 129(3):1030-1046.
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A tale of the twist in the outflow graft: An analysis from the MOMENTUM 3 trial. J Heart Lung Transplant. 2018 11; 37(11):1281-1284.
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Enhancement of mitochondrial biogenesis and paradoxical inhibition of lactate dehydrogenase mediated by 14-3-3? in oncocytomas. J Pathol. 2018 07; 245(3):361-372.
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In Vitro and In Vivo Characterization of a Preclinical Irradiation-Adapted Model for Ewing Sarcoma. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):118-127.
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Early intervention for lactate dehydrogenase elevation improves clinical outcomes in patients with the HeartMate II left ventricular assist device: Insights from the PREVENT study. J Heart Lung Transplant. 2018 01; 37(1):25-32.