"Pentylenetetrazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
| Descriptor ID |
D010433
|
| MeSH Number(s) |
D03.383.066.600
|
| Concept/Terms |
Pentylenetetrazole- Pentylenetetrazole
- Pentylenetetrazol
- Pentetrazole
- Leptazole
- Pentamethylenetetrazole
Corasol- Corasol
- Corazole
- Korazole
- Corazol
- Korazol
|
Below are MeSH descriptors whose meaning is more general than "Pentylenetetrazole".
Below are MeSH descriptors whose meaning is more specific than "Pentylenetetrazole".
This graph shows the total number of publications written about "Pentylenetetrazole" by people in this website by year, and whether "Pentylenetetrazole" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentylenetetrazole" by people in Profiles.
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Downregulation of CD40L-CD40 attenuates seizure susceptibility and severity of seizures. Sci Rep. 2021 08 26; 11(1):17262.
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Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene. Hippocampus. 2002; 12(2):258-68.
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Role of tissue hypoxia in local regulation of cerebral microcirculation. Am J Physiol. 1978 May; 234(5):H582-91.