Raghu Mirmira to Insulin
This is a "connection" page, showing publications Raghu Mirmira has written about Insulin.
Connection Strength
4.683
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Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes. Diabetes. 2015 Nov; 64(11):3867-72.
Score: 0.354
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Achieving "PeaK-A" insulin secretion. Diabetes. 2013 May; 62(5):1389-90.
Score: 0.303
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Development of insulin-producing cells from primitive biologic precursors. Curr Opin Organ Transplant. 2009 Feb; 14(1):56-63.
Score: 0.226
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Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene. J Biol Chem. 2008 Mar 28; 283(13):8164-72.
Score: 0.211
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Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets. Diabetes. 2007 Mar; 56(3):827-35.
Score: 0.197
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Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1. Mol Endocrinol. 2006 Dec; 20(12):3133-45.
Score: 0.190
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Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem. 2005 Oct 28; 280(43):36244-53.
Score: 0.178
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The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter. Biochemistry. 2005 Aug 23; 44(33):11269-78.
Score: 0.178
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Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem. 2005 Apr 29; 280(17):16798-807.
Score: 0.172
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Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells. J Biol Chem. 2003 Jun 27; 278(26):23617-23.
Score: 0.151
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Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice. J Diabetes Complications. 2021 02; 35(2):107795.
Score: 0.128
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Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes. Clin Epigenetics. 2020 07 31; 12(1):116.
Score: 0.125
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Nanomedicine-Based Strategies for Diabetes: Diagnostics, Monitoring, and Treatment. Trends Endocrinol Metab. 2020 06; 31(6):448-458.
Score: 0.122
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Circulating Unmethylated Insulin DNA As a Biomarker of Human Beta Cell Death: A Multi-laboratory Assay Comparison. J Clin Endocrinol Metab. 2020 03 01; 105(3).
Score: 0.122
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Combined Analysis of GAD65, miR-375, and Unmethylated Insulin DNA Following Islet Transplantation in Patients With T1D. J Clin Endocrinol Metab. 2019 02 01; 104(2):451-460.
Score: 0.113
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Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes. Diabetes Obes Metab. 2019 01; 21(1):95-102.
Score: 0.109
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1,25-Dihydroxyvitamin D3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vitamin D receptor. J Steroid Biochem Mol Biol. 2019 01; 185:17-26.
Score: 0.109
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Elevated unmethylated and methylated insulin DNA are unique markers of A+ß+ ketosis prone diabetes. J Diabetes Complications. 2018 02; 32(2):193-195.
Score: 0.103
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12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets. J Clin Endocrinol Metab. 2017 08 01; 102(8):2789-2797.
Score: 0.102
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Loss of mTORC1 signalling impairs ß-cell homeostasis and insulin processing. Nat Commun. 2017 07 12; 8:16014.
Score: 0.101
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Peroxisome Proliferator-activated Receptor-? Activation Augments the ß-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and ß Cell Death in Non-obese Diabetic Mice. J Biol Chem. 2016 Oct 21; 291(43):22524-22533.
Score: 0.096
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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion. Mol Endocrinol. 2015 Jul; 29(7):1055-66.
Score: 0.088
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.
Score: 0.081
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Palmitate induces mRNA translation and increases ER protein load in islet ß-cells via activation of the mammalian target of rapamycin pathway. Diabetes. 2014 Oct; 63(10):3404-15.
Score: 0.081
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Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus. J Clin Endocrinol Metab. 2014 May; 99(5):E866-70.
Score: 0.080
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Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes. J Biol Chem. 2013 Dec 20; 288(51):36226-35.
Score: 0.078
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Detection of islet ß-cell death in vivo by multiplex PCR analysis of differentially methylated DNA. Endocrinology. 2013 Sep; 154(9):3476-81.
Score: 0.077
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Translational control of inducible nitric oxide synthase by p38 MAPK in islet ß-cells. Mol Endocrinol. 2013 Feb; 27(2):336-49.
Score: 0.074
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Disposition of the phenylalanine B25 side chain during insulin-receptor and insulin-insulin interactions. Biochemistry. 1991 Aug 20; 30(33):8222-9.
Score: 0.067
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Importance of the character and configuration of residues B24, B25, and B26 in insulin-receptor interactions. J Biol Chem. 1991 Jan 25; 266(3):1428-36.
Score: 0.065
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AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. Mol Cell Endocrinol. 2010 Jul 29; 323(2):246-55.
Score: 0.061
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Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation. J Biol Chem. 1989 Apr 15; 264(11):6349-54.
Score: 0.057
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Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure. Mol Cell Biol. 2009 Apr; 29(8):2053-67.
Score: 0.057
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Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets. Diabetes. 2008 Feb; 57(2):424-31.
Score: 0.052
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The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells. Proc Natl Acad Sci U S A. 2005 May 17; 102(20):7297-302.
Score: 0.044
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The role of beta-cell dysfunction in early type 1 diabetes. Curr Opin Endocrinol Diabetes Obes. 2020 08; 27(4):215-224.
Score: 0.031
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Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains. J Biol Chem. 2000 May 12; 275(19):14743-51.
Score: 0.031
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The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter. Mol Cell Biol. 2000 Feb; 20(3):900-11.
Score: 0.030
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Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264. Diabetes Care. 2019 05; 42(5):e85-e86.
Score: 0.029
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Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care. 2019 02; 42(2):258-264.
Score: 0.028
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Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function. PLoS One. 2018; 13(5):e0197080.
Score: 0.027
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Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. Diabetologia. 2016 Jan; 59(1):151-160.
Score: 0.023
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Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes. Sci Signal. 2015 Jan 27; 8(361):ra10.
Score: 0.021
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Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One. 2013; 8(2):e56763.
Score: 0.019
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Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors. J Biol Chem. 1993 Feb 15; 268(5):3044-7.
Score: 0.019
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Oscillatory glucose flux in INS 1 pancreatic ß cells: a self-referencing microbiosensor study. Anal Biochem. 2011 Apr 15; 411(2):185-93.
Score: 0.016
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An insulin-like growth factor I/insulin hybrid exhibiting high potency for interaction with the type I insulin-like growth factor and insulin receptors of placental plasma membranes. J Biol Chem. 1990 Oct 15; 265(29):17820-5.
Score: 0.016
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The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Mol Endocrinol. 2010 Jul; 24(7):1423-33.
Score: 0.015
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Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling. J Biol Chem. 2010 Feb 19; 285(8):5392-404.
Score: 0.015
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Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. Mol Cell Biol. 2008 May; 28(10):3465-76.
Score: 0.013