"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 17 | 11 | 28 |
| 1997 | 12 | 11 | 23 |
| 1998 | 13 | 4 | 17 |
| 1999 | 5 | 15 | 20 |
| 2000 | 18 | 11 | 29 |
| 2001 | 10 | 10 | 20 |
| 2002 | 12 | 10 | 22 |
| 2003 | 10 | 9 | 19 |
| 2004 | 12 | 12 | 24 |
| 2005 | 14 | 9 | 23 |
| 2006 | 14 | 9 | 23 |
| 2007 | 12 | 13 | 25 |
| 2008 | 11 | 15 | 26 |
| 2009 | 14 | 22 | 36 |
| 2010 | 15 | 14 | 29 |
| 2011 | 9 | 6 | 15 |
| 2012 | 10 | 9 | 19 |
| 2013 | 13 | 19 | 32 |
| 2014 | 16 | 16 | 32 |
| 2015 | 18 | 16 | 34 |
| 2016 | 8 | 10 | 18 |
| 2017 | 19 | 8 | 27 |
| 2018 | 14 | 21 | 35 |
| 2019 | 8 | 12 | 20 |
| 2020 | 7 | 9 | 16 |
| 2021 | 7 | 16 | 23 |
| 2022 | 0 | 10 | 10 |
| 2023 | 3 | 11 | 14 |
| 2024 | 4 | 2 | 6 |
| 2025 | 6 | 5 | 11 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Regulatory Roles of IGF2R in Insulin Secretion and Adaptive ß-Cell Proliferation. Diabetes. 2025 Dec 01; 74(12):2351-2364.
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Genome-wide CRISPR Screen Identifies Sec31A as a Key Regulator of Alpha Cell Survival. Nat Commun. 2025 Oct 15; 16(1):9159.
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Predictors of Diabetes Outcomes at 1 Year After Islet Autotransplantation: Data From a Multicenter Cohort Study. Diabetes Care. 2025 Sep 01; 48(9):1493-1501.
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Smaller Pancreas Volume in Insulin-Dependent Monogenic Diabetes. Diabetes. 2025 Aug 01; 74(8):1411-1416.
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Metabolic Models, in Silico Trials, and Algorithms. J Diabetes Sci Technol. 2025 Jul; 19(4):895-907.
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Research Gaps, Challenges, and Opportunities in Automated Insulin Delivery Systems. J Diabetes Sci Technol. 2025 Jul; 19(4):937-949.
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Research Gaps, Challenges, and Opportunities in Automated Insulin Delivery Systems. Diabetes Technol Ther. 2025 Jul; 27(S3):S60-S71.
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Metabolic Models, in Silico Trials, and Algorithms. Diabetes Technol Ther. 2025 Jul; 27(S3):S21-S32.
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Approach to the Patient Using Diabetes Technology in Pregnancy. J Clin Endocrinol Metab. 2025 Jun 17; 110(7):e2317-e2326.
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The Role, Potential Benefits and Cost-effectiveness of Digital Tools for Diabetes Management. Clin Ther. 2025 Aug; 47(8):638-648.