"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 9 | 11 | 20 |
| 1996 | 17 | 10 | 27 |
| 1997 | 12 | 11 | 23 |
| 1998 | 13 | 4 | 17 |
| 1999 | 5 | 15 | 20 |
| 2000 | 16 | 11 | 27 |
| 2001 | 10 | 10 | 20 |
| 2002 | 12 | 10 | 22 |
| 2003 | 10 | 9 | 19 |
| 2004 | 12 | 12 | 24 |
| 2005 | 14 | 8 | 22 |
| 2006 | 14 | 9 | 23 |
| 2007 | 11 | 13 | 24 |
| 2008 | 11 | 15 | 26 |
| 2009 | 13 | 22 | 35 |
| 2010 | 15 | 13 | 28 |
| 2011 | 8 | 6 | 14 |
| 2012 | 11 | 9 | 20 |
| 2013 | 13 | 20 | 33 |
| 2014 | 14 | 16 | 30 |
| 2015 | 18 | 16 | 34 |
| 2016 | 8 | 10 | 18 |
| 2017 | 18 | 8 | 26 |
| 2018 | 14 | 21 | 35 |
| 2019 | 8 | 12 | 20 |
| 2020 | 7 | 8 | 15 |
| 2021 | 7 | 15 | 22 |
| 2022 | 0 | 9 | 9 |
| 2023 | 3 | 11 | 14 |
| 2024 | 4 | 1 | 5 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic ß-cell function in obese male mice. Nat Commun. 2025 May 21; 16(1):4714.
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Analysis of the Dynamics of a Complex, Multipathway Reaction: Insulin Dimer Dissociation. J Phys Chem B. 2024 Dec 26; 128(51):12728-12740.
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Consensus Report on Glucagon-Like Peptide-1 Receptor Agonists as Adjunctive Treatment for Individuals With Type 1 Diabetes Using an Automated Insulin Delivery System. J Diabetes Sci Technol. 2025 Jan; 19(1):191-216.
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Food Insecurity and Hypoglycemia among Older Patients with Type 2 Diabetes Treated with Insulin or Sulfonylureas: The Diabetes & Aging Study. J Gen Intern Med. 2024 Oct; 39(13):2400-2406.
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SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes. J Clin Invest. 2024 May 07; 134(12).
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INTERACTIONS OF METFORMIN AND OTHER MEDICATIONS IN REDUCING THE ODDS OF AGE-RELATED MACULAR DEGENERATION IN A COHORT OF PATIENTS WITH DIABETES. Retina. 2024 02 01; 44(2):197-204.
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Geometric and topological characterization of the cytoarchitecture of islets of Langerhans. PLoS Comput Biol. 2023 Nov; 19(11):e1011617.
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Multivariable Automated Insulin Delivery System for Handling Planned and Spontaneous Physical Activities. J Diabetes Sci Technol. 2023 11; 17(6):1456-1469.
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Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. Diabetes Care. 2023 10 01; 46(10):1740-1746.
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Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. Diabetes Care. 2023 10 01; 46(10):e151-e199.