"Sphingomyelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of sphingolipids found largely in the brain and other nervous tissue. They contain phosphocholine or phosphoethanolamine as their polar head group so therefore are the only sphingolipids classified as PHOSPHOLIPIDS.
| Descriptor ID |
D013109
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| MeSH Number(s) |
D09.400.410.420.525.870 D10.390.470.675.870 D10.570.755.893 D10.570.877.360.612.870
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sphingomyelins".
Below are MeSH descriptors whose meaning is more specific than "Sphingomyelins".
This graph shows the total number of publications written about "Sphingomyelins" by people in this website by year, and whether "Sphingomyelins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sphingomyelins" by people in Profiles.
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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. Cell Rep. 2021 11 02; 37(5):109957.
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CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field. J Chem Theory Comput. 2016 Jan 12; 12(1):405-13.
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Multiple sphingolipid abnormalities following cerebral microendothelial hypoxia. J Neurochem. 2014 Nov; 131(4):530-40.
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CHARMM all-atom additive force field for sphingomyelin: elucidation of hydrogen bonding and of positive curvature. Biophys J. 2014 Jul 01; 107(1):134-45.
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Evidence for coordination of lysosomal (ASMase) and plasma membrane (NSMase2) forms of sphingomyelinase from mutant mice. FEBS Lett. 2012 Nov 16; 586(22):4002-9.
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Differential regulation of sphingomyelin synthesis and catabolism in oligodendrocytes and neurons. J Neurochem. 2008 Aug; 106(4):1745-57.
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Cellular sphingolipids regulate macrophage apolipoprotein E secretion. Biochemistry. 2007 Oct 02; 46(39):11196-204.
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Caveolin-1 in extracellular matrix vesicles secreted from osteoblasts. Bone. 2007 Jul; 41(1):52-8.
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Scrambling of phospholipids activates red cell membrane cholesterol. Biochemistry. 2007 Feb 27; 46(8):2233-8.
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Protection of membrane cholesterol by sphingomyelin against free radical-mediated oxidation. Free Radic Biol Med. 2006 Jun 15; 40(12):2092-102.