"Trifluridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)
| Descriptor ID |
D014271
|
| MeSH Number(s) |
D03.383.742.680.705.900 D13.570.230.855.900 D13.570.685.705.900
|
| Concept/Terms |
Trifluridine- Trifluridine
- Trifluorothymidine
- 2'-deoxy-5-(trifluoromethyl)uridine
- Trifluoridine
- 5-Trifluoromethyl-2'-deoxyuridine
- 5 Trifluoromethyl 2' deoxyuridine
|
Below are MeSH descriptors whose meaning is more general than "Trifluridine".
Below are MeSH descriptors whose meaning is more specific than "Trifluridine".
This graph shows the total number of publications written about "Trifluridine" by people in this website by year, and whether "Trifluridine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trifluridine" by people in Profiles.
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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study. Lancet. 2023 07 01; 402(10395):41-53.
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Trifluridine/tipiracil versus placebo for third or later lines of treatment in metastatic gastric cancer: an exploratory subgroup analysis from the TAGS study. ESMO Open. 2021 08; 6(4):100200.
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Efficacy and Safety of Trifluridine/Tipiracil Treatment in Patients With Metastatic Gastric Cancer Who Had Undergone Gastrectomy: Subgroup Analyses of a Randomized Clinical Trial. JAMA Oncol. 2020 Jan 01; 6(1):e193531.
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Pediatric herpes simplex of the anterior segment: characteristics, treatment, and outcomes. Ophthalmology. 2012 Oct; 119(10):2003-8.
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Quantitative 19F NMR study of trifluorothymidine metabolism in rat brain. NMR Biomed. 1999 Oct; 12(6):373-80.
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Pilot study of topical trifluridine for the treatment of acyclovir-resistant mucocutaneous herpes simplex disease in patients with AIDS (ACTG 172). AIDS Clinical Trials Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Jun 01; 12(2):147-52.
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Herpes simplex keratitis in patients with acquired immune deficiency syndrome. Ophthalmology. 1989 Oct; 96(10):1476-9.
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Trifluridine decreases ocular HSV-1 recovery, but not herpetic lesions after timolol iontophoresis. Invest Ophthalmol Vis Sci. 1989 Apr; 30(4):678-83.
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Therapy for human herpesvirus infections. A perspective. Ala J Med Sci. 1985 Apr; 22(2):193-207.
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Current status of antiviral chemotherapy. South Med J. 1978 Sep; 71(9):1134-40.