"Vaccines, Attenuated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity.
| Descriptor ID |
D014613
|
| MeSH Number(s) |
D20.215.894.811
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Vaccines, Attenuated".
Below are MeSH descriptors whose meaning is more specific than "Vaccines, Attenuated".
This graph shows the total number of publications written about "Vaccines, Attenuated" by people in this website by year, and whether "Vaccines, Attenuated" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 4 | 4 |
| 2014 | 0 | 3 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 3 | 3 |
| 2021 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Vaccines, Attenuated" by people in Profiles.
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Development and preclinical evaluation of next-generation ?sigH-based live candidate vaccines. JCI Insight. 2025 Oct 08; 10(19).
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Prevention of tuberculosis in cynomolgus macaques by an attenuated Mycobacterium tuberculosis vaccine candidate. Nat Commun. 2025 Feb 25; 16(1):1957.
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Mpox Clinical Presentation, Diagnostic Approaches, and Treatment Strategies: A Review. JAMA. 2024 11 19; 332(19):1652-1662.
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Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine. JCI Insight. 2024 Apr 30; 9(11).
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Teach 'em young: Influenza vaccines induce broadly neutralizing antibodies in children. Cell Rep Med. 2022 02 15; 3(2):100531.
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Old vaccines for new infections: Exploiting innate immunity to control COVID-19 and prevent future pandemics. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial. Lancet Infect Dis. 2020 01; 20(1):80-91.
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Rough Brucella neotomae provides protection against Brucella suis challenge in mice. Vet Microbiol. 2019 Dec; 239:108447.
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Cell-mediated immune responses to different formulations of a live-attenuated tetravalent dengue vaccine candidate in subjects living in dengue endemic and non-endemic regions. Hum Vaccin Immunother. 2019; 15(9):2090-2105.
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Development of an auxotrophic, live-attenuated Brucella suis vaccine strain capable of expressing multimeric GnRH. Vaccine. 2019 02 08; 37(7):910-914.