"Cytochalasin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
| Descriptor ID |
D015638
|
| MeSH Number(s) |
D03.633.100.473.231.450 D23.946.587.370.450
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cytochalasin D".
Below are MeSH descriptors whose meaning is more specific than "Cytochalasin D".
This graph shows the total number of publications written about "Cytochalasin D" by people in this website by year, and whether "Cytochalasin D" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochalasin D" by people in Profiles.
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A mechanism for actin filament severing by malaria parasite actin depolymerizing factor 1 via a low affinity binding interface. J Biol Chem. 2014 Feb 14; 289(7):4043-54.
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Independent migration of cell populations in the early gastrulation of the amphipod crustacean Parhyale hawaiensis. Dev Biol. 2012 Nov 01; 371(1):94-109.
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Role of cytoskeleton in controlling the disorder strength of cellular nanoscale architecture. Biophys J. 2010 Aug 04; 99(3):989-96.
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The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility. Traffic. 2010 Jun; 11(6):782-99.
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Role of membrane microdomains in PTH-mediated down-regulation of NaPi-IIa in opossum kidney cells. Kidney Int. 2005 Sep; 68(3):1137-47.
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Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration. Mol Cell Biol. 2004 Feb; 24(4):1628-39.
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Rho kinase inhibition initiates apoptosis in human airway epithelial cells. Am J Respir Cell Mol Biol. 2004 Mar; 30(3):379-87.
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Initiation of apoptosis by actin cytoskeletal derangement in human airway epithelial cells. Am J Respir Cell Mol Biol. 2001 Mar; 24(3):282-94.
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Neuroprotection mediated by changes in the endothelial actin cytoskeleton. J Clin Invest. 2000 Jul; 106(1):15-24.
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Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins. J Biol Chem. 1999 Nov 19; 274(47):33522-30.