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Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5.
Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors.
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Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5.
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. Science. 2021 06 04; 372(6546):1085-1091.
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PubMed
subject areas
Adipose Tissue
Alleles
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Animals
Brain
Cell Line
Chromatin
Embryonic Development
Enhancer Elements, Genetic
Feeding Behavior
Food Preferences
Gene Expression Regulation
Haplotypes
Homeodomain Proteins
Humans
Male
Mice
Mice, Inbred C57BL
Neurons
Obesity
Polymorphism, Single Nucleotide
Transcription Factors
authors with profiles
Noboru Sakabe
Carole Ober
Marcelo A. Nobrega