"Saposins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of four homologous sphingolipid activator proteins that are formed from proteolytic cleavage of a common protein precursor molecule referred to as prosaposin.
Descriptor ID |
D049231
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MeSH Number(s) |
D08.211.790.500
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Concept/Terms |
Saposin B- Saposin B
- Sphingolipid Activator Protein 1
- Sphingolipid Activator Protein-1
- SAP-1 Sphingolipid Activator
- SAP 1 Sphingolipid Activator
- Sphingolipid Activator, SAP-1
Saposin C- Saposin C
- beta-Glucosidase Stimulating Protein
- beta Glucosidase Stimulating Protein
- Co-beta-Glucosidase
- Co beta Glucosidase
- Sphingolipid Activator Protein 2
- Gaucher Activator Protein
- Glucosylceramidase Activator
- SAP-C Protein
- SAP C Protein
- beta-Glucosidase Activator Protein
- beta Glucosidase Activator Protein
- Coglucosidase
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Below are MeSH descriptors whose meaning is more general than "Saposins".
Below are MeSH descriptors whose meaning is more specific than "Saposins".
This graph shows the total number of publications written about "Saposins" by people in this website by year, and whether "Saposins" was a major or minor topic of these publications.
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Below are the most recent publications written about "Saposins" by people in Profiles.
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Alpha anomers of iGb3 and Gb3 stimulate cytokine production by natural killer T cells. ACS Chem Biol. 2009 Mar 20; 4(3):199-208.
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Lysosomal glycosphingolipid recognition by NKT cells. Science. 2004 Dec 03; 306(5702):1786-9.
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Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science. 2004 Jan 23; 303(5657):523-7.
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Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids. Hum Mol Genet. 1996 Jun; 5(6):711-25.