Receptors, Polymeric Immunoglobulin
"Receptors, Polymeric Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
| Descriptor ID |
D019056
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| MeSH Number(s) |
D12.776.543.750.705.871.700
|
| Concept/Terms |
Receptors, Polymeric Immunoglobulin- Receptors, Polymeric Immunoglobulin
- Polymeric Immunoglobulin Receptors
- Immunoglobulin Receptors, Polymeric
- Receptor, Polyimmunoglobulin
- Receptor, Polymeric Ig
- Poly-Ig Receptor
- Poly Ig Receptor
- Receptor, Poly-Ig
- Polyimmunoglobulin Receptor
- Polymeric Immunoglobulin Receptor
- Immunoglobulin Receptor, Polymeric
- Receptor, Polymeric Immunoglobulin
- Polymeric Ig Receptor
- Ig Receptor, Polymeric
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Polymeric Immunoglobulin".
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This graph shows the total number of publications written about "Receptors, Polymeric Immunoglobulin" by people in this website by year, and whether "Receptors, Polymeric Immunoglobulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Polymeric Immunoglobulin" by people in Profiles.
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Identification of the Fc-alpha/mu receptor in Xenopus provides insight into the emergence of the poly-Ig receptor (pIgR) and mucosal Ig transport. Eur J Immunol. 2021 11; 51(11):2590-2606.
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Putting J chain back on the map: how might its expression define plasma cell development? J Immunol. 2014 Oct 01; 193(7):3248-55.
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Protection from Clostridium difficile infection in CD4 T Cell- and polymeric immunoglobulin receptor-deficient mice. Infect Immun. 2014 Feb; 82(2):522-31.
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Cranberry proanthocyanidins improve intestinal sIgA during elemental enteral nutrition. JPEN J Parenter Enteral Nutr. 2014 Jan; 38(1):107-14.
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Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides. Mucosal Immunol. 2012 Sep; 5(5):501-12.
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Polymeric immunoglobulin receptor in intestinal immune defense against the lumen-dwelling protozoan parasite Giardia. J Immunol. 2006 Nov 01; 177(9):6281-90.
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Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients. J Hum Genet. 2003; 48(6):293-299.