Heparan Sulfate Proteoglycans
"Heparan Sulfate Proteoglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)
| Descriptor ID |
D019812
|
| MeSH Number(s) |
D09.698.373.425.500 D09.698.735.400 D12.776.395.650.350
|
| Concept/Terms |
Heparan Sulfate Proteoglycans- Heparan Sulfate Proteoglycans
- Proteoglycans, Heparan Sulfate
- Sulfate Proteoglycans, Heparan
- HSPG
- Proteoheparan Sulfate
- Heparan Sulfate Proteoglycan
- Proteoglycan, Heparan Sulfate
|
Below are MeSH descriptors whose meaning is more general than "Heparan Sulfate Proteoglycans".
Below are MeSH descriptors whose meaning is more specific than "Heparan Sulfate Proteoglycans".
This graph shows the total number of publications written about "Heparan Sulfate Proteoglycans" by people in this website by year, and whether "Heparan Sulfate Proteoglycans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 2000 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heparan Sulfate Proteoglycans" by people in Profiles.
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Mapping Proteoglycan Function Using Novel Genetic Strategies. Methods Mol Biol. 2022; 2303:731-752.
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Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing. Nat Biomed Eng. 2020 04; 4(4):463-475.
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Dynamic regulation of basement membrane protein levels promotes egg chamber elongation in Drosophila. Dev Biol. 2015 Oct 15; 406(2):212-21.
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Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infect Immun. 2015 Sep; 83(9):3648-56.
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The polybasic insertion in autotaxin a confers specific binding to heparin and cell surface heparan sulfate proteoglycans. J Biol Chem. 2013 Jan 04; 288(1):510-9.
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Heparan sulfate sulfatase SULF2 regulates PDGFRa signaling and growth in human and mouse malignant glioma. J Clin Invest. 2012 Mar; 122(3):911-22.
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Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis. Diabetologia. 2011 Jun; 54(6):1527-38.
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Stromal endothelial cells directly influence cancer progression. Sci Transl Med. 2011 Jan 19; 3(66):66ra5.
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Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate. Development. 2009 May; 136(10):1697-706.
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Role of cellular heparan sulfate proteoglycans in infection of human adenovirus serotype 3 and 35. PLoS Pathog. 2008 Oct; 4(10):e1000189.