"Endocardial Cushions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fetal heart structure that is the bulging areas in the cardiac septum between the HEART ATRIA and the HEART VENTRICLES. During development, growth and fusion of endocardial cushions at midline forms the two atrioventricular canals, the sites for future TRICUSPID VALVE and BICUSPID VALVE.
| Descriptor ID |
D054089
|
| MeSH Number(s) |
A07.541.459.374 A16.378.303.662
|
| Concept/Terms |
Endocardial Cushions- Endocardial Cushions
- Endocardial Cushion
- Atrioventricular Canal Cushions
- Atrioventricular Canal Cushion
|
Below are MeSH descriptors whose meaning is more general than "Endocardial Cushions".
Below are MeSH descriptors whose meaning is more specific than "Endocardial Cushions".
This graph shows the total number of publications written about "Endocardial Cushions" by people in this website by year, and whether "Endocardial Cushions" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endocardial Cushions" by people in Profiles.
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ß-Catenin regulates endocardial cushion growth by suppressing p21. Life Sci Alliance. 2023 09; 6(9).
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FRS2a-dependent cell fate transition during endocardial cushion morphogenesis. Dev Biol. 2020 02 01; 458(1):88-97.
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Myocardial ß-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation. J Mol Cell Cardiol. 2018 10; 123:150-158.
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BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling. Dev Biol. 2017 10 01; 430(1):113-128.
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Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis. Development. 2013 Aug; 140(15):3176-87.
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Nfatc1 directs the endocardial progenitor cells to make heart valve primordium. Trends Cardiovasc Med. 2013 Nov; 23(8):294-300.
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The secondary heart field is a new site of calcineurin/Nfatc1 signaling for semilunar valve development. J Mol Cell Cardiol. 2012 May; 52(5):1096-102.
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Cell autonomous requirement of endocardial Smad4 during atrioventricular cushion development in mouse embryos. Dev Dyn. 2011 Jan; 240(1):211-20.