"Photobleaching" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Light-induced change in a chromophore, resulting in the loss of its absorption of light of a particular wave length. The photon energy causes a conformational change in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS in the CELL MEMBRANE.
| Descriptor ID |
D038761
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| MeSH Number(s) |
G02.740.680
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Photobleaching".
Below are MeSH descriptors whose meaning is more specific than "Photobleaching".
This graph shows the total number of publications written about "Photobleaching" by people in this website by year, and whether "Photobleaching" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Photobleaching" by people in Profiles.
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Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9365-9376.
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4D Microscopy of Yeast. J Vis Exp. 2019 04 28; (146).
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A microfluidic device for measuring cell migration towards substrate-bound and soluble chemokine gradients. Sci Rep. 2016 11 07; 6:36440.
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Skeletal light-scattering accelerates bleaching response in reef-building corals. BMC Ecol. 2016 Mar 21; 16:10.
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Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):4121-6.
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Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios. Biophys J. 2010 Nov 17; 99(10):L81-3.
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The use of fluorescence redistribution after photobleaching for analysis of cellular microtubule dynamics. Methods Cell Biol. 2010; 97:35-52.
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Nanometer-localized multiple single-molecule fluorescence microscopy. Proc Natl Acad Sci U S A. 2004 Aug 03; 101(31):11298-303.