Cleavage Stimulation Factor
"Cleavage Stimulation Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
| Descriptor ID |
D039241
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| MeSH Number(s) |
D12.776.157.725.124.249 D12.776.664.962.444.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cleavage Stimulation Factor".
Below are MeSH descriptors whose meaning is more specific than "Cleavage Stimulation Factor".
This graph shows the total number of publications written about "Cleavage Stimulation Factor" by people in this website by year, and whether "Cleavage Stimulation Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cleavage Stimulation Factor" by people in Profiles.
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Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer. Clin Cancer Res. 2011 Sep 15; 17(18):5889-900.