"Stem Cell Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hematopoietic growth factor and the ligand of the cell surface c-kit protein (PROTO-ONCOGENE PROTEINS C-KIT). It is expressed during embryogenesis and is a growth factor for a number of cell types including the MAST CELLS and the MELANOCYTES in addition to the HEMATOPOIETIC STEM CELLS.
| Descriptor ID |
D019089
|
| MeSH Number(s) |
D12.644.276.374.410.800 D12.776.467.374.410.800 D23.529.374.410.800
|
| Concept/Terms |
Stem Cell Factor- Stem Cell Factor
- Steel Factor
- Mast Cell Growth Factor
- c-kit Ligand
- c kit Ligand
- kit Ligand
|
Below are MeSH descriptors whose meaning is more general than "Stem Cell Factor".
Below are MeSH descriptors whose meaning is more specific than "Stem Cell Factor".
This graph shows the total number of publications written about "Stem Cell Factor" by people in this website by year, and whether "Stem Cell Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Stem Cell Factor" by people in Profiles.
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Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity. Arthritis Rheumatol. 2016 10; 68(10):2492-502.
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Stem cell factor expression in B cell malignancies is influenced by the niche. Leuk Lymphoma. 2013 Oct; 54(10):2274-80.
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Distinct functions of erythropoietin and stem cell factor are linked to activation of mTOR kinase signaling pathway in human erythroid progenitors. Cytokine. 2013 Jan; 61(1):329-35.
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SALL4, a stem cell factor, affects the side population by regulation of the ATP-binding cassette drug transport genes. PLoS One. 2011 Apr 19; 6(4):e18372.
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Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science. 2008 Dec 19; 322(5909):1861-5.
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Osteopontin regulates actin cytoskeleton and contributes to cell proliferation in primary erythroblasts. J Biol Chem. 2008 Mar 14; 283(11):6997-7006.
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Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells. Oncogene. 2002 Feb 28; 21(10):1556-62.
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Optimization of culture conditions to enhance transfection of human CD34+ cells by electroporation. Bone Marrow Transplant. 2001 Jun; 27(11):1201-9.
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Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors. Biochem Biophys Res Commun. 2000 Aug 18; 275(1):16-9.
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Interferon gamma delays apoptosis of mature erythroid progenitor cells in the absence of erythropoietin. Blood. 2000 Jun 15; 95(12):3742-9.