"Receptor, EphB4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eph family receptor found in a variety of adult and embryonic tissues. Unlike the majority of proteins in this class there is little or no expression of EphB4 receptor in the BRAIN. It has been found at high levels in developing mammary glands and in invasive mammary tumors.
| Descriptor ID |
D036224
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.850.750 D12.776.543.750.630.500.781
|
| Concept/Terms |
Receptor, EphB4- Receptor, EphB4
- EPHB4 Protein
- Hepatoma Transmembrane Kinase
- Kinase, Hepatoma Transmembrane
- Transmembrane Kinase, Hepatoma
- EphB4 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, EphB4".
Below are MeSH descriptors whose meaning is more specific than "Receptor, EphB4".
This graph shows the total number of publications written about "Receptor, EphB4" by people in this website by year, and whether "Receptor, EphB4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, EphB4" by people in Profiles.
-
EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells. Cell Death Dis. 2019 10 22; 10(11):801.
-
EphB4: A promising target for upper aerodigestive malignancies. Biochim Biophys Acta Rev Cancer. 2018 Apr; 1869(2):128-137.
-
Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer. Sci Rep. 2015 Jun 15; 5:10641.
-
Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition. Growth Factors. 2014 Dec; 32(6):202-6.
-
The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target. PLoS One. 2013; 8(7):e67668.
-
EphB4 as a therapeutic target in mesothelioma. BMC Cancer. 2013 May 30; 13:269.
-
Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers. Cancer Res. 2013 Jan 01; 73(1):184-94.
-
Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants. Genesis. 2010 Mar; 48(3):146-50.
-
Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels. Blood. 2004 Jan 01; 103(1):100-9.