"Tissue Distribution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
| Descriptor ID |
D014018
|
| MeSH Number(s) |
G03.787.917 G07.690.725.949
|
| Concept/Terms |
Tissue Distribution- Tissue Distribution
- Distribution, Tissue
- Distributions, Tissue
- Tissue Distributions
|
Below are MeSH descriptors whose meaning is more general than "Tissue Distribution".
Below are MeSH descriptors whose meaning is more specific than "Tissue Distribution".
This graph shows the total number of publications written about "Tissue Distribution" by people in this website by year, and whether "Tissue Distribution" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 12 | 12 |
| 1995 | 0 | 11 | 11 |
| 1996 | 0 | 6 | 6 |
| 1997 | 0 | 4 | 4 |
| 1998 | 0 | 5 | 5 |
| 1999 | 0 | 8 | 8 |
| 2000 | 0 | 11 | 11 |
| 2001 | 0 | 8 | 8 |
| 2002 | 0 | 10 | 10 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 10 | 10 |
| 2005 | 0 | 9 | 9 |
| 2006 | 0 | 8 | 8 |
| 2007 | 0 | 10 | 10 |
| 2008 | 0 | 6 | 6 |
| 2009 | 0 | 6 | 6 |
| 2010 | 0 | 8 | 8 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 8 | 8 |
| 2014 | 0 | 10 | 10 |
| 2015 | 0 | 8 | 8 |
| 2016 | 0 | 5 | 5 |
| 2017 | 0 | 5 | 5 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 8 | 8 |
| 2020 | 0 | 5 | 5 |
| 2021 | 0 | 4 | 4 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tissue Distribution" by people in Profiles.
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Head-to-head comparison of three chelates reveals DOTAGA promising for 225 Ac labeling of anti-FZD10 antibody OTSA101. Cancer Sci. 2023 Dec; 114(12):4677-4690.
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Linking Body Composition and Nutritional Status with CAR T-cell Efficacy. Cancer Immunol Res. 2023 06 02; 11(6):704.
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A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer. Nat Commun. 2022 08 17; 13(1):4829.
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FZD10-targeted a-radioimmunotherapy with 225 Ac-labeled OTSA101 achieves complete remission in a synovial sarcoma model. Cancer Sci. 2022 Feb; 113(2):721-732.
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The Use of Contrast Agents in Interventional Pain Procedures: A Multispecialty and Multisociety Practice Advisory on Nephrogenic Systemic Fibrosis, Gadolinium Deposition in the Brain, Encephalopathy After Unintentional Intrathecal Gadolinium Injection, and Hypersensitivity Reactions. Anesth Analg. 2021 08 01; 133(2):535-552.
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Near-Equivalence: Generating Evidence to Support Alternative Cost-Effective Treatments. J Clin Oncol. 2021 03 20; 39(9):950-955.
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Assessment of Brain Glucose Metabolism Following Cardiac Arrest by [18F]FDG Positron Emission Tomography. Neurocrit Care. 2021 02; 34(1):64-72.
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Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J Med Chem. 2020 07 09; 63(13):7186-7210.
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Iron kinetics following treatment with sucroferric oxyhydroxide or ferric citrate in healthy rats and models of anaemia, iron overload or inflammation. Nephrol Dial Transplant. 2020 06 01; 35(6):946-954.
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Clinical Activity and Safety of Atezolizumab in a Phase 1 Study of Patients With Relapsed/Refractory Small-Cell Lung Cancer. Clin Lung Cancer. 2020 09; 21(5):455-463.e4.