"Freeze Substitution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A modification of the freeze-drying method in which the ice within the frozen tissue is replaced by alcohol or other solvent at a very low temperature.
Descriptor ID |
D017110
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MeSH Number(s) |
E01.370.225.500.620.760.160.260.270 E01.370.225.750.600.760.160.260.270 E02.792.156.260.270 E05.200.500.620.760.160.260.270 E05.200.750.600.760.160.260.270 E05.760.156.260.270
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Freeze Substitution".
Below are MeSH descriptors whose meaning is more specific than "Freeze Substitution".
This graph shows the total number of publications written about "Freeze Substitution" by people in this website by year, and whether "Freeze Substitution" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Freeze Substitution" by people in Profiles.
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High-pressure freezing and freeze substitution of Arabidopsis for electron microscopy. Methods Mol Biol. 2014; 1062:473-86.
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Electron tomographic analysis of somatic cell plate formation in meristematic cells of Arabidopsis preserved by high-pressure freezing. Plant Cell. 2004 Apr; 16(4):836-56.