Leukocyte Common Antigens
"Leukocyte Common Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
| Descriptor ID |
D017493
|
| MeSH Number(s) |
D08.811.277.352.650.775.400.100.500 D12.644.360.587.100.500 D12.776.476.592.100.500 D12.776.543.733.937.500
|
| Concept/Terms |
Leukocyte Common Antigens- Leukocyte Common Antigens
- Antigens, Leukocyte Common
- CD45 Antigens
- Antigens, CD45
- Protein Tyrosine Phosphatase, Receptor Type, C
- L-CA Antigens
- Antigens, L-CA
- L CA Antigens
- Leukocyte Common Antigen
- Antigen, Leukocyte Common
- CD45 Antigen
- Antigen, CD45
- T200 Antigens
- Antigens, T200
CD45RO Antigens- CD45RO Antigens
- Antigens, CD45RO
- CD45R0 Antigens
- Antigens, CD45R0
B220 Antigens- B220 Antigens
- Antigens, B220
- CD45R Antigens
- Antigens, CD45R
- B220 Antigen
- Antigen, B220
|
Below are MeSH descriptors whose meaning is more general than "Leukocyte Common Antigens".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Common Antigens".
This graph shows the total number of publications written about "Leukocyte Common Antigens" by people in this website by year, and whether "Leukocyte Common Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 0 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 4 | 5 |
| 2003 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 3 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 3 | 3 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukocyte Common Antigens" by people in Profiles.
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Ligand-induced segregation from large cell-surface phosphatases is a critical step in ?d TCR triggering. Cell Rep. 2024 Sep 24; 43(9):114761.
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Physical tuning of galectin-3 signaling. Proc Natl Acad Sci U S A. 2021 05 11; 118(19).
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Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer. Eur J Cancer. 2021 06; 150:83-94.
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Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin. Nat Immunol. 2021 02; 22(2):154-165.
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Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses. Immunity. 2019 07 16; 51(1):155-168.e5.
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Immunofluorescence staining of live lymph node tissue slices. J Immunol Methods. 2019 01; 464:119-125.
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Distinct roles of intracellular heat shock protein 70 in maintaining gastrointestinal homeostasis. Am J Physiol Gastrointest Liver Physiol. 2018 02 01; 314(2):G164-G178.
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Association of synovial inflammation and inflammatory mediators with glenohumeral rotator cuff pathology. J Shoulder Elbow Surg. 2016 Jun; 25(6):989-97.
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Acquisition of Portal Venous Circulating Tumor Cells From Patients With Pancreaticobiliary Cancers by Endoscopic Ultrasound. Gastroenterology. 2015 Dec; 149(7):1794-1803.e4.
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Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry. Am J Clin Pathol. 2015 Apr; 143(4):527-34.