"Chemokine CCL21" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards DENDRITIC CELLS and T-LYMPHOCYTES.
| Descriptor ID |
D054421
|
| MeSH Number(s) |
D12.644.276.374.200.110.890 D12.776.467.374.200.110.890 D23.125.300.110.890 D23.469.200.110.890 D23.529.374.200.110.890
|
| Concept/Terms |
Chemokine CCL21- Chemokine CCL21
- CCL21, Chemokine
- 6Ckine
- SLC Chemokine
- Chemokine, SLC
- Exodus-2 Chemokine
- Chemokine, Exodus-2
- Exodus 2 Chemokine
- Secondary Lymphoid-Tissue Chemokine
- Chemokine, Secondary Lymphoid-Tissue
- Lymphoid-Tissue Chemokine, Secondary
- Secondary Lymphoid Tissue Chemokine
- Thymus-Derived Chemotactic Agent 4
- Thymus Derived Chemotactic Agent 4
- CCL21 Chemokine
- Chemokine, CCL21
|
Below are MeSH descriptors whose meaning is more general than "Chemokine CCL21".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CCL21".
This graph shows the total number of publications written about "Chemokine CCL21" by people in this website by year, and whether "Chemokine CCL21" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 2 | 2 | 4 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chemokine CCL21" by people in Profiles.
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Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma. Sci Transl Med. 2017 Sep 13; 9(407).
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A microfluidic device for measuring cell migration towards substrate-bound and soluble chemokine gradients. Sci Rep. 2016 11 07; 6:36440.
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Tumor-induced stromal reprogramming drives lymph node transformation. Nat Immunol. 2016 09; 17(9):1118-27.
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Immunotherapy and tumor microenvironment. Cancer Lett. 2016 Jan 01; 370(1):85-90.
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Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia. J Immunol. 2013 May 01; 190(9):4608-20.
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Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19. Proc Natl Acad Sci U S A. 2011 Apr 05; 108(14):5614-9.
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Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science. 2010 May 07; 328(5979):749-52.
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Transmural flow modulates cell and fluid transport functions of lymphatic endothelium. Circ Res. 2010 Mar 19; 106(5):920-31.
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In a murine tuberculosis model, the absence of homeostatic chemokines delays granuloma formation and protective immunity. J Immunol. 2009 Dec 15; 183(12):8004-14.
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Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment. J Immunol. 2009 Oct 01; 183(7):4273-83.